KR102427909B1 - Rfume composition for olfactory stimuli and controlling brain waves using natural extracts - Google Patents

Abstract

The present invention relates to a fragrance composition for olfactory stimulation and EEG control comprising a natural extract, and contains a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof, and has excellent EEG control effect by stimulating the sense of smell Thus, there is provided a perfume composition exhibiting an effect of improving concentration and stabilizing the mind and body.

Description

Fragrance composition for olfactory stimulation and brain wave control containing natural extracts

The present invention relates to a fragrance composition for olfactory stimulation and brain wave control comprising a natural extract. More specifically, it relates to a perfume composition comprising a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof, and has excellent brain wave control effect by stimulating the sense of smell, thereby improving concentration and stabilizing mind and body .

The olfactory system is divided into a primary olfactory system and a secondary olfactory system. It is known that the secondary olfactory organ responds to stimulation of liquid particles, and the main olfactory system responds to volatile gas particles. Humans respond to odor substances inhaled through the nose through the main olfactory organ, and the inhaled odor substances come into contact with the olfactory epithelium, which is composed of a number of olfactory sensory cells. The olfactory sensory cells that have received the odor stimulus transmit a signal to the mitral cells through the glomerulus, and this electrical stimulation is transmitted to various parts of the telencephalon through the posterior nerve fibers. In addition, the human sense of smell is a sophisticated sensory organ that can distinguish thousands of organic compounds, and it is known that the sense of smell is closely related to emotions. A number of researchers are using the EEG technique to objectify changes in sensitivity and sensation caused by olfactory stimulation.

Neurons that make up the human cerebral cortex are constantly undergoing microscopic electrical activity. EEG is a measurement of potential fluctuations occurring for the scalp through the tissues covering the cerebral cortex, the skull, and the scalp. To measure EEG, electrodes are attached to the scalp and electrical signals generated from the brain are input to the EEG to record potentials over time. The result obtained in this way is called an EEG or electroencephalogram (EEG). EEG has the advantage of being able to record temporally and spatially and temporally changing brain activity fluctuations and non-invasively and continuously and simply measure brain function. It is widely used and known to be used in cognitive science, medicine, and pharmaceutical fields.

When plant essential oil is inhaled, volatile aromatic compounds contained in essential oil reach the olfactory epithelium through the nasal passages, and the olfactory nerve cells in the olfactory epithelium sense it and transmit an electrical signal to the brain. It is known that each essential oil generates a unique brain wave.

Accordingly, there is a growing interest in aroma therapy using plant essential oils, and the discovery of functional plant essential oils is required due to its high utility in various fields such as cosmetics, cosmetics and health and hygiene products.

KR 10-2019-0119824 A

An object of the present invention is to provide a fragrance composition for olfactory stimulation and brain wave control comprising a natural extract.

Another object of the present invention is to provide a fragrance composition comprising a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof, and has excellent EEG control effect by stimulating the sense of smell, thereby improving concentration and stabilizing mind and body. will provide

In order to achieve the above object, the perfume composition according to an embodiment of the present invention contains a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof, and has excellent brain wave control effect by stimulating the sense of smell .

The EEG control effect is to decrease the beta wave (bata(β) wave) and increase the alpha wave (alph(α) wave).

The composition further comprises a natural extract, wherein the natural extract further comprises selected from the group consisting of carob extract (Ceratonia siliqua), calluna extract (Calluna vulgaris), black seed extract (Nigella sativa), and mixtures thereof do.

The extract is extracted using an extraction solvent selected from the group consisting of water, C ₁ to C ₆ lower alcohols, and mixtures thereof.

The perfume composition is excellent in concentration enhancement, mental and physical stability and stress relief effect.

A skin home care product according to another embodiment of the present invention is prepared by using the perfume composition.

A personal care product according to another embodiment of the present invention is prepared by using the perfume composition.

Hereinafter, the present invention will be described in more detail.

As used herein, the term 'extract' has the meaning commonly used as a crude extract in the art as described above, but in a broad sense also includes a fraction obtained by additionally fractionating the extract. That is, the extract includes not only those obtained using the above-described extraction solvent, but also those obtained by additionally applying a purification process thereto. For example, a fraction obtained by passing the extract through an ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography (prepared for separation according to size, charge, hydrophobicity or affinity), etc. The fraction obtained through the purification method is also included in the extract of the present invention.

The fragrance composition according to an embodiment of the present invention contains a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof, and has excellent EEG control effect by stimulating the sense of smell.

Herbal plants are herbaceous plants whose flowers, seeds, stems, leaves, and roots are useful for humans. Since ancient times, they have played an important role as medicinal herbs for pain relief and sedation, as well as for antiseptic and insecticidal properties. It is a natural material that is attracting more and more attention due to the toxicity of the material, concerns about environmental pollution, and its excellent efficacy.

Rose geranium (Pelargonium rosium) is a cultivar of herbal geranium that is native to Egypt, and is characterized by a rose scent from leaves and stems. The genus name, pelargonium, comes from the Latin word pelargos, meaning 'Stork', because the seed resembles the beak of a stork. It is also called Gumuncho because its unique scent repels mosquitoes. Grows to 30-60 cm in height. Stems are straight, unbranched and covered with hairs. The leaves are pinnate compound leaves (dendritic leaves), which are deeply split, and the split pieces are split again and have sawtooths on the edge. Pink or rosy flowers bloom from April to June and have no fragrance. Petals are covered with fluff and veins are visible. The fruit is in the shape of a pod that looks like a bird's beak, and has five chambers, each containing a seed.

Rosemary is a perennial evergreen deciduous tree in the family Lamiaceae, which usually grows over 1 meter. The narrow, thin needle-shaped leaves have a leather-like quality, are shiny, have a characteristic strong aroma, and are dark green. It has sterilization and disinfection action, so it was used to preserve meat, and it was often used in hospitals or when infectious diseases were prevalent. Rosemary helps to improve memory, revitalizes the symptoms of lethargy, and relieves headaches and migraines. In addition, it has an anti-obesity effect, regenerates the skin, revitalizes the sagging tissue, suppresses the occurrence of edema and dandruff, and promotes hair growth. Rosemary is used for cooking, facial cleansing, and to increase blood pressure when you have low blood pressure.

Lavender is one of the most well-known herbs. It is popular as an ornamental herb because the aromatic oil component makes the leaves and flower surfaces appear shiny, and their splendor shines even more during the flowering period. High-quality lavender is used for many purposes, especially flowers, leaves, stems, and the like, so it is suitable for ornamental purposes as well as potpourri and various cosmetic products. Dried flowers are dried in the morning by cutting the purple buds before flowering and hanging them in the shade with good ventilation. For ornamental use, cut off after the flowers have faded, leaving about 2 stalks. The lotion made with the essential oil of lavender is effective for rough skin because it has a cleansing effect that relaxes and relieves the skin and regenerates it clean and moist. Also, the scent of lavender has a calming effect, so it was put in a pillow and used for sleep. Brewed tea with lavender is effective for sedation, relieves pain and headaches, and helps you sleep better by changing your mood.

The perfume composition comprising a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof according to the present invention, while emitting the original flavor, reduces the absolute value of the overall EEG and increases the relative alpha wave among EEG It can have the function of improving concentration by enabling positive brain activity along with mental and physical relaxation (stabilization).

The EEG control effect is to decrease the beta wave (bata(β) wave) and increase the alpha wave (alph(α) wave).

Depending on the frequency range, EEG is delta wave (0.5~3Hz), theta wave (4~7Hz), alpha wave (8~13Hz), beta wave (14~30Hz) , and gamma waves (30Hz or higher).

Delta wave is a wave with a frequency of less than 4Hz in EEG. In the wake state, like theta wave, delta wave cannot be seen in adults, but appears to some extent in EEG of infants and children. Since delta waves appear even in the moderate and deep sleep phases, as with theta waves, the appearance of delta waves should be judged whether or not pathological by sufficiently considering age and the state at the time of examination. Like theta waves, delta waves have pathological meanings, such as occult lesions such as brain tumors, cerebrovascular disorders, epilepsy, and various symptoms of brain dysfunction such as hypoglycemia or hypoxia.

Theta wave is a wave with a frequency of 4 to 7 Hz in the brain wave, and it passes through when falling asleep. It is associated with a deeply internalized and quiet state of physical, emotional and thought activity, and is not only creative and spontaneous, but also associated with confusion, distraction, daydreaming, depression, and anxiety.

Alpha waves are waves with a frequency of 8 to 13 Hz in EEG, appear most frequently, and occupy most of the resting, arousal, and pulmonary eye of a normal adult. Therefore, it is the brain wave that comes out most when the mind and body are relaxed and feels comfortable, and has a lot to do with meditation and inner stillness or peace.

Beta waves are irregular waves with a frequency of 14 to 30 Hz in brain waves, and are also brain waves that change when sensory stimulation is applied to alpha waves. It appears when performing a normal task or performing a conscious action, and is activated when there is a mental activity such as information processing. In particular, it increases as alpha waves are suppressed by excitement, anxiety, or tension.

Gamma waves come from a state of extreme arousal and excitement.

As described above, olfactory stimulation by odor is transmitted to various parts of the central nervous system and causes a wide range of activity across the forebrain to change brain waves, so it can be analyzed through the degree of brain activation by olfactory stimulation. Therefore, it is possible to improve the stabilization and function of the brain by controlling the EEG.

The composition further comprises a natural extract, wherein the natural extract further comprises selected from the group consisting of carob extract (Ceratonia siliqua), calluna extract (Calluna vulgaris), black seed extract (Nigella sativa), and mixtures thereof do.

Carob (Ceratonia siliqua) is an evergreen broad-leaved shrub up to 10 m tall and drought tolerant. The leaves contain resin. Small, dull greenish-brown flowers bloom in autumn, with long green pods running. These pods turn chocolate when ripe and contain small, shiny hard beans. Carob gum, which softens the skin, is popular as a skin pack and is also used to treat diarrhea.

Calluna vulgaris (Calluna vulgaris) is the only species of the genus Calluna in the monomorphic genus of the Rhododendron family. The place of origin is from Siberia through Turkey and Europe to North Africa and Macaronesia. It is an evergreen small shrub about 60 cm tall and has strong cold resistance. The branches spread sideways and grow densely. The leaves are scale-like, about 2-3 mm, and they are densely attached to the branches and face each other. The flowers are small bell-shaped in June-September, closely attached to the m part from the middle of the branch, and there are horticultural varieties of various colors based on white and pink colors.

Nigella sativa is an annual or biennial plant of the dicotyledonous plant Heterinaceae. It is an annual plant that grows about 50-80cm, and the leaves are divided 3 or 4 times into an upper right corner and have a glossy appearance in the shape of a cosmos leaf. Flowers hang one at the end of branches in light purple color in June-July. The fruits are plump and spherical, and the seeds are small and black and ripen in August-September. It is called black seed plant because the seeds are black, and it is native to southern Europe. Strawberry-flavored black seed seed has a spicy nutmeg flavor that is widespread in India, Egypt, Greece, and Turkey. Raw and dried seeds add flavor to curry, vegetable and bean dishes.

When the natural extract is further included, the EEG control effect due to the olfactory stimulation is excellent, so that it reduces the beta wave (bata(β) wave) and increases the alpha wave (alph(α) wave), so that it has excellent concentration It can be provided as a perfume composition exhibiting an improvement and mental and physical stabilization effect.

In addition, as the carob extract (Ceratonia siliqua), calluna extract (Calluna vulgaris), and black seed extract (Nigella sativa) are additionally used in combination, the fragrance is stronger than when using only rose geranium, rosemary and lavender extracts. The preference for the perfume increases, making it possible to provide a perfume composition with high preference.

Preferably, the composition of the present invention is based on 100 parts by weight of the rose geranium extract, 100 parts by weight of the rosemary extract, 100 parts by weight of the lavender extract, 20 to 40 parts by weight of the carob extract, 20 to 40 parts by weight of the caluna extract, and 20 to 40 parts by weight of the black seed extract. It may be included in 40 parts by weight. When used as a complex extract within the above range, it is possible to provide an excellent EEG control effect due to olfactory stimulation, and to provide a fragrance composition with excellent fragrance preference.

The extract is extracted using an extraction solvent selected from the group consisting of water, C ₁ to C ₆ lower alcohols, and mixtures thereof.

Specifically, pulverizing a natural product to prepare a natural extract; leaching the pulverized product using an organic solvent; drying the sample after leaching; re-leaching the dried sample using an organic solvent; drying the sample after leaching; leaching with water; And including the step of leaching, it is possible to obtain a natural extract.

The natural extract extracted using the organic solvent may further include the step of performing fractionation using an organic solvent.

The extraction solvent may be used in an amount of 2 to 50 times, more specifically, 2 to 20 times, based on the weight of the sample. For extraction, the sample may be left for 1 to 72 hours for leaching in the extraction solvent, and more specifically, for 24 to 48 hours.

The extract may be prepared in a powder state by additional processes such as vacuum distillation and freeze drying or spray drying, and is obtained by an extraction method selected from the group consisting of solvent extraction method, ultrasonic extraction method, reflux extraction method, leaching method, fermentation method and foaming method. include that

In the ultrasonic extraction method, the reaction is performed at 30 to 50° C. for 0.5 to 2.5 hours, and the extraction solvent is water or 50 to 100% alcohol having 1 to 6 carbon atoms. Specifically, extraction is performed at 40 to 50° C. for 1 to 2.5 hours, and the extraction solvent is water or 70 to 80% alcohol having 1 to 6 carbon atoms.

The reflux extraction method is based on 100 mL of water, an alcohol having 1 to 6 carbon atoms, 10 to 30 g of a pulverized product of a natural product, a reflux time of 1 to 3 hours, and 50 to 100% alcohol or water having 1 to 6 carbon atoms. More specifically, based on 100 mL of alcohol having 1 to 6 carbon atoms or 100 mL of water, 10 to 20 g of a pulverized product of natural products, 1 to 2 hours reflux, and 70 to 90% alcohol or water having 1 to 4 carbon atoms.

The leaching method is carried out at 15 to 30° C. for 24 to 72 hours, and water or 50 to 100% alcohol having 1 to 6 carbon atoms is used as an extraction solvent. More specifically, the process is carried out at 20 to 25° C. for 30 to 54 hours, and the extraction solvent is water or 70 to 80% alcohol having 1 to 6 carbon atoms.

After extraction, the extract may be fractionated by sequentially applying a fresh fractionation solvent. The fractionation solvent used for fractionation is any one or more selected from the group consisting of water, hexane, butanol, ethyl acetic acid, ethyl acetate, methylene chloride and mixtures thereof, preferably ethyl acetate or methylene chloride.

The perfume composition according to the present invention, while emitting the original flavor, reduces the absolute value of the overall brain wave and increases the relative alpha wave among the brain waves, thereby improving concentration by enabling positive brain activity as well as mental and physical relaxation (stabilization). Because it has functionality, it can be used not only as a conventional perfume and incense, but also can be used for aromatherapy for tension relief, stress relief, psychological stability and concentration enhancement.

The perfume composition is excellent in concentration enhancement, mental and physical stability and stress relief effect.

A skin home care product according to another embodiment of the present invention is prepared by using the perfume composition.

As another aspect of the present invention, there is provided a home care product for suppressing off-flavor comprising the perfume composition.

In the present invention, "home care products" refer to products used for household use for cleaning surfaces or maintaining sanitary conditions, such as in kitchens and bathrooms (eg, hard surface cleaners, manual and automatic dish care, toilet bowl cleaners and disinfectants, dishwashing detergent), products intended for use in laundry products such as textile care and cleaning (e.g. detergents, fabric softeners, pre-stain removers), release fragrances to remove odors, and in some cases used as perfume replacements including, but not limited to, a fragrance, and the like, and may be applied to all home care compositions in which fragrance is added.

Specifically, home care products include laundry detergents, laundry detergent additives, laundry bars, fabric softeners, dishwashing agents, wood and furniture polishes, floor polishes, bathtub and tile cleaners, toilet seat cleaners, hard surface cleaners, window cleaners, antifogging agents, drain cleaners, self-dishwashers and sheeting agents, carpet cleaners, prewash spotters, rust stain cleaners, scale removers, deodorants and air fresheners.

The home care product of the present invention, such as a product for use in laundry products, may be, but is not limited to, a textile care product comprising the perfume composition and a cationic polymer, an amphoteric surfactant, or a mixture thereof. The cationic polymer used in the textile care product is cationic guar, cationic cellulose, dimethyldiallylammonium chloride polymer, acrylamide-dimethyldiallylammonium chloride copolymer, PVP-dimethylaminoethylmethacrylate copolymer, acrylic acid- Any one or more selected from the group consisting of dimethyldiallylammonium chloride copolymer, acrylamide-dimethylamino ethyl methacrylate methyl chloride copolymer, and trimethylaminoethyl methacrylate polymer may be used, but is not limited thereto. The amphoteric surfactant used in textile care products is selected from the group consisting of alkylamidopropylbetaine, alkyldimethylbetaine, alkylmonoamphoacetate, cocoamphocarboxy glycinate, sarcosinate and alkylamphodiacetate. Any one or more selected may be used, but is not limited thereto.

The home care product of the present invention, such as a product for use in laundry products, may be, but is not limited to, a laundry detergent product comprising the perfume composition and a nonionic surfactant, an anionic surfactant, or a mixture thereof. The nonionic surfactant used in laundry detergent products may be at least one selected from the group consisting of fatty acid alkyl polyoxyethylene glycol, fatty acid polyoxyethylene glycol, alkylphenyl polyoxyethylene glycol, polyoxyethylene glycol, and the like. , but not limited.

The anionic surfactant used in the laundry detergent product may be any one or more selected from the group consisting of linear alkylbenzenesulfonate, fatty acid salt, alkylsulfonate, or alpha olefinsulfonate, but is not limited thereto.

While the home care products of the present invention, such as those intended for use in such laundry products, require several cleaning additives, certain simple formulations, such as bleach additives, may require only oxygen bleach and surfactants. The cleaning adducts may include builders, enzymes, bleach, bleach activators, catalyst materials, and the like.

Specifically, the cleaning additive is a foam accelerator, a foam inhibitor (antifoam agent), a dispersant polymer, a color speckle, a silver care agent, an anti-discoloration agent and/or an anti-corrosive agent, a dye, a filler, a bactericide, an alkali source, an aromatic substance, an antioxidant. It may contain various active ingredients or specialized substances such as agents, enzyme stabilizers, pro-flavors, fragrances, solubilizers, carriers, processing aids, pigments, and in the case of liquid formulations, solvents, chelating agents, dye transfer inhibitors, dispersants, brighteners, foam suppressants, dyes, structural elastomeric agents, fabric softeners, anti-wear agents, hydrotropes, processing aids, and other fabric care, surface and skin care agents.

The home care product of the present invention, such as perfume, may be a volatile perfume comprising the perfume composition of the present invention in gel form or solidified form of the present invention, and may be a spray perfume containing the perfume composition of the present invention prepared in a liquid form. have. In addition, the fragrance may include 0.001 to 30% by weight, specifically 1 to 30% by weight, more specifically 1 to 10% by weight of the fragrance composition of the present invention based on the weight of the total product. When the fragrance composition is added in an amount of less than 0.001% by weight of the total composition, it is difficult to appreciate the fragrance due to very low fragrance, and when it is added in an amount of more than 30% by weight, the fragrance is too strong to be used as a fragrance.

When the perfume composition of the present invention is used as a perfume additive, the composition may be added as it is or mixed with optional ingredients useful for flavor or perfume. In particular, they may be admixed with one or more of a wide variety of natural, synthetic, synthetic chemicals, natural fragrances, flavoring substances, flavorings or natural extracts used in the field of perfumery.

In addition, perfumes may include flavoring agents and one or more ingredients or excipients commonly used with perfumes, such as carrier materials, thickeners, flavor enhancers and other adjuvants commonly known and used in the art. can

As another aspect of the present invention, there is provided a personal care product comprising the perfume composition.

In the present invention, "personal care product" refers to cosmetics, hair care products, toiletries, cosmeceuticals, beauty supplements, insect repellents applied to the body including human and animal skin, hair, scalp, and nails. , personal care and cleansing products, but is not limited thereto, and may be applied to all personal care compositions in which fragrance is added.

Specifically, deodorants, antiperspirants, sprays, stick and roll-on products, shaving agents, skin lotions, moisturizers, toners, bath products, cleansing agents, shampoos, conditioners, combined shampoos/conditioners, mousses, styling gels, hair Spray, hair dye, hair colorant, hair bleach, waving agent, hair straightener, nail polish, nail polish remover, nail cream and lotion, keratin emollient, sunscreen, insect repellent, anti-aging agent, lipstick, foundation, face powder, eyeliner , eye shadow, blushes, makeup, mascara, moisturizing preparation, body and hand preparation, skincare preparation, face and neck preparation, tonic, dressing, hair grooming aid, aerosol pixative, fragrance preparation, aftershave, make -Up formulations, soft focus products, night and day skin care formulations, non-pigmented hair formulations, tanning aids, synthetic and non-synthetic soap bars, hand liquids, nose strips, non-woven products for personal care, baby lotions, baby baths and Shampoo, baby conditioner, shaving aid, cue cumber slice, skin pad, makeup remover, facial cleansing agent, cold cream, sunscreen, mousse, spritze, paste mask and mud, face mask, cologne and lotion, hair cuticle Coat, shower gel, face and body wash, personal care rinse-off agent, gel, foam bath, scrubbing cleanser, astringent, nail conditioner, eyeshadow stick, face or eye powder, lip balm, lip gloss, hair care pump spray and more Non-aerosol spray, hair-freeze control gel, hair leave-in conditioner, hair pomade, hair detangling agent, hair fixative, hair bleach, skin lotion, pre-shave and pre-electric shave, dry cream and lotion, oil /water type, water/type, multiple macro and micro emulsion, water resistant cream and lotion, acne skin preparation, mouthwash, massage oil, toothpaste, clear gel and stick, ointment base, topical wound healing agent, aerosol talc, barrier spray, vitamin and anti-aging preparations, herbal extract preparations, bath salts, bath and body milks, hair styling aids, hair-, eye-, nail- and skin-soft products, controlled release personal care agents, hair conditioning mists, skin care moisturizing mists, skin wipes, pore skin wipes, pore cleansers, blemish reducers, skin exfoliators, exfoliators, skin towels and cloths, depilatory agents, personal care lubricants, and nail color aids.

The personal care products of the present invention, such as cosmetics, are solutions, external ointments, creams, foams, nourishing lotions, softening lotions, packs, soft water, emulsions, makeup bases, essences, soaps, liquid detergents, bathing agents, sunscreen creams, sun oils. , suspensions, emulsions, pastes, gels, lotions, powders, soaps, surfactant-containing cleansing, oils, powder foundations, emulsion foundations, wax foundations, patches and sprays, It is not limited thereto.

The cosmetic of the present invention may further include one or more cosmetically acceptable carriers to be formulated in general skin cosmetics, and conventional ingredients include, for example, oil, water, surfactant, humectant, lower alcohol, thickener, chelate. Agents, dyes, preservatives, fragrances and the like may be appropriately mixed, but the present invention is not limited thereto. The cosmetically acceptable carrier included in the cosmetic of the present invention varies depending on the formulation.

When the formulation of the present invention is an ointment, paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide as a carrier component or mixtures thereof may be used.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder or a mixture thereof may be used as a carrier component, and in particular, in the case of a spray, additional chloro propellants such as fluorohydrocarbons, propane/butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butylglycol oil may be used, and in particular, cottonseed oil, peanut oil, corn germ oil, olive oil, castor oil and sesame oil, glycerol fatty ester, fatty acid ester of polyethylene glycol or sorbitan may be used. have.

When the formulation of the present invention is a suspension, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester; Crystalline cellulose, aluminum metahydroxide, bentonite, agar or tracanth may be used.

When the formulation of the present invention is a soap, alkali metal salts of fatty acids, fatty acid hemiester salts, fatty acid protein hydrolysates, isethionate, lanolin derivatives, aliphatic alcohols, vegetable oils, glycerol, sugar, etc. may be used as carrier components. can

In the cosmetic of the present invention, the content of the perfume composition may vary depending on the formulation. For example, wash-off type cosmetics such as makeup removers and detergents in which active ingredients stay on the skin within a short period of time may have a relatively high concentration. On the other hand, in the case of leave-on type cosmetics, such as lotions, emulsions, creams, and essences, where the active ingredient stays on the skin for a long time, it may be ok to include a lower concentration compared to wash-off type cosmetics. .

Personal care products, such as hair care products, of the present invention include shampoos (including complex shampoos such as two-in-one conditioning shampoos), hair conditioners, post-shampoo rinses, hair dyes, setting, styling and style retainers (including setting aids such as gels and sprays, and grooming aids such as pomades, conditioners, perms, and relaxants), hair smoothing products, but are not limited thereto.

The hair care product may include, but is not limited to, the fragrance composition of the present invention and at least one selected from the group consisting of cationic surfactants, amphoteric surfactants, nonionic surfactants, and cationic polymers. The cationic surfactant used in hair care products may be any one or more selected from the group consisting of cetrimonium chloride, stearamidopropyldimethylamine, dicetyldimethylammonium chloride and ester quattro. It is not limited thereto.

The amphoteric surfactant used in the hair care product may be at least one selected from the group consisting of cocamidopropylbetaine, cocoamphocarboxyglycinate and cocoamphocarboxypropionate, but is not limited thereto.

The nonionic surfactant used in hair care products is at least one selected from the group consisting of lauryl acid diethanolamide, palm oil fatty acid diethanolamide, palm oil fatty acid monoethanolamide, lauryl dimethylamine oxide, and palm oil alkyldimethylamine oxide. may be used, but is not limited thereto. The cationic polymer used in hair care products includes a group of natural cationic polymers consisting of guarhydroxypropyltrimonium chloride, hydroxypropylguahydroxypropyltrimonium chloride and quaternary hydroxyethylcellulose; and a synthetic cationic polymer group consisting of dimethyldiallylammonium chloride polymer, crylamide dimethyl allylammonium chloride copolymer, and polyvinylpyrrolidone dimethylaminoethyl methacrylate copolymer; Not limited. The hair dye may be a hair dye including the perfume composition of the present invention, a precursor, and a coupler, but is not limited thereto.

The personal care products, such as body care products, of the present invention may be used as single ingredients for bath and shower additives, formulations containing fragrance and flavoring substances, hair care products, deodorants and antiperspirants, decorative formulations, active ingredient-containing photoprotective formulations and formulations or other It may be used in combination with a stabilizer.

Said body care products include body oils, body lotions, body gels, treatment creams, skin protection ointments, shaving preparations such as shaving foams or gels, skin powders such as baby powder, moisturizing gel, moisturizing spray, revital including, but not limited to, rising body sprays, cellulite gels, and peeling formulations.

Suitable bath and shower additives include shower gels, bath-salts, bubble baths and soaps. Formulations containing fragrance and flavor substances include perfumes, lotions, and shaving lotions (aftershave preparations). The body care product may be in the form of a cream, ointment, paste, foam, gel, lotion, powder, makeup, spray, stick or aerosol, but is not limited thereto.

The body care product may also include, but is not limited to, stabilizing mixtures, and optionally additional UV absorbers, sterically hindered amines, complexing agents, and phenolic or non-phenolic antioxidants.

According to the fragrance composition for olfactory stimulation and EEG control comprising the natural extract of the present invention, a fragrance excellent in EEG control effect by stimulating the sense of smell, including a natural extract selected from the group consisting of rose geranium, rosemary, lavender and mixtures thereof compositions may be provided.

1 is a result of stimulating the sense of smell using a perfume composition according to an embodiment of the present invention, and showing the effect of improving nerve stability and concentration.

Hereinafter, embodiments of the present invention will be described in detail so that those of ordinary skill in the art can easily carry out the present invention. However, the present invention may be embodied in several different forms and is not limited to the embodiments described herein.

[Preparation Example 1: Preparation of Perfume Composition]

1. Preparation of Rose Geranium Extract

The rose geranium was thoroughly washed under running water and then completely air-dried. The dried rose geranium was pulverized with a blender and then prepared into powder. 50% ethanol as an extraction solvent was added to the powder sample at a ratio of 1;10 (w; v), and then completely immersed, and extracted three times for 3 hours while refluxing at 80°C. The extract is Whatman No. 2 filtered with filter paper. The filtrate was concentrated under reduced pressure at 60° C. to prepare a rose geranium extract (PGE).

2. Manufacture of other natural extracts

Using the same method as the production method of the rose geranium extract (PGE), rosemary extract (POE), lavender extract (LOE), carob extract (KH), caluna extract (CE) and black sesame extract (NE) were prepared did.

3. Preparation of perfume composition

The rose geranium extract (PGE), rosemary extract (POE), lavender extract (LOE), carob extract (KH), caluna extract (CE) and black sesame extract (NE) were mixed as shown in Table 1 below to prepare a fragrance composition. prepared.

PX1 PX2 PX3 PX4 PX5 PX6 PGE 100 100 100 100 100 100 POE 100 100 100 100 100 100 LOE 100 100 100 100 100 100 KE - 10 20 30 40 50 CE - 10 20 30 40 50 NE - 10 20 30 40 50

(Unit: parts by weight)

[Experimental Example 1: EEG control effect according to olfactory stimulation]

1. EEG control effect of fragrance composition PX1

In order to confirm the EEG control efficacy of the fragrance composition PX1, a microwave mobile (MindWave Mobile) imported from Neurosky in the United States was used as an EEG measuring device. It was used by wearing it on the head.

This EEG sensor detects beta waves from concentration and excitement and alpha waves from relaxation and stable emotions, and displays attention and meditation values between 0 and 100, respectively.

Seventeen healthy subjects who had never suffered from mental illness were selected and kept calm for 5 minutes. After that, a stomach headset, an EEG measuring device, was placed on the subject's forehead, and the results were obtained after measuring EEG for 2 minutes. After spraying PX1 on the test paper, the subject was allowed to smell for 2 minutes, and EEG was simultaneously measured while smelling. (attention) values were analyzed.

The values of attention and meditation are between 0 and 100, where 0 to 25 is the hypo index (inability to concentrate or distraction), and 25 to 30 is the normal index (normal state). , 50 to 75 indicates the active index (active state), and 75 to 100 indicates the hyper index (exaggerated value).

When measured by EEG response with an EEG meter, the number of times the concentration and meditation levels existed in the 0~25, 25~50, 50~75, and 75~100 areas for a certain period of time is counted. In this experiment, the subject The number of times concentration and meditation were counted in each index area through an EEG while sniffing was subtracted from the number of times concentration and meditation were counted in each index area through an EEG before stimulating the sense of smell with PX1. did.

The results are shown in FIG. 1 below, and the horizontal axis of FIG. 1 represents the 0-25 (hypo), 25-50 (normal), 50-75 (active), 75-100 (hyper) regions of concentration and meditation. respectively, and the vertical axis shows the difference in the number of counts of concentration and meditation in each index area after stimulation of the sense of smell with the PX1 and before stimulation. When the value on the vertical axis is (+), it means that the number of times the EEG stayed in the index area after olfactory stimulation by PX1 is greater, and when the value on the vertical axis is (-), the number of times the EEG stayed in the index area after the olfactory stimulation by PX1 is (-) is rather less. 5 shows the average value of 17 subjects. As a result of stimulating the sense of smell with the fragrance composition, the number of times that both the concentration and meditation values stayed within the normal or activity index range increased more than before stimulation of the sense of smell. EEG control and thus stability and concentration improvement effects were confirmed.

2. EEG control effect of complex fragrance composition

The EEG control effect of the remaining perfume compositions PX2 to PX6 was confirmed in the same manner as the perfume composition PX1, which confirmed the EEG control effect according to the olfactory stimulus.

For the relative evaluation, the degree of anti-inflammatory effect of the perfume composition PX1 was set to an index of 5, and the degree of EEG modulating effect for other complex perfume compositions was described as an index.

EEG control effect results for the complex perfume composition are shown in Table 2 below.

PX1 PX2 PX3 PX4 PX5 PX6 EEG control effect 5 6 8 8 9 7

(Unit: Index)

As shown in Table 2, as a result of comparison with the perfume composition PX1 for the EEG control effect, it was confirmed that PX2 to PX6 exhibited an excellent EEG control effect equal to or greater than that of PX6.

In particular, it exhibited a significantly superior EEG control effect in PX3 to PX6 further containing carob extract (KH), kaluna extract (CE) and black sesame extract (NE).

[Experimental Example 2: Evaluation of Smell Preference]

The olfactory preference through olfactory stimulation was measured for the prepared perfume compositions (PX1 to PX6). Concentrations of all fragrances were measured by XP-329IIIR (COSMOS, japan), and the fragrance composition was sufficiently wetted in square gauze (25cm ² ) at the same concentration and used.

The olfactory stimulation was measured for a total of 7 minutes in the order of 2 minutes of olfactory stimulation and 5 minutes of rest at a position 2 cm in front of the nose by placing the perfume composition in a conical tube, respectively, and repeated measurements for each fragrance 8 times. In order to reduce the olfactory fatigue that can be experienced by subjects who experience various fragrances, on the first day, stimulation with two fragrances was tested and conducted over a total of three days.

The results are expressed as average values, and are expressed as an exponent of 1 to 10. In the index, the higher the number, the better the olfactory preference.

The results are shown in Table 3 below.

PX1 PX2 PX3 PX4 PX5 PX6 olfactory preference 5.4 6.2 6.8 7.2 7.8 6.4

(Unit: Index)

As shown in Table 3, it was confirmed that the complex perfume composition exhibited a relatively higher olfactory preference than that of the perfume composition containing rose geranium, rosemary, and lavender.

In particular, in the case of PX3 to PX5, it was confirmed that the preference for the olfactory stimulus was increased.

Although preferred embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and various modifications and improvements by those skilled in the art using the basic concept of the present invention as defined in the following claims are also provided. is within the scope of the

Claims (7)

It contains rose geranium extract, rosemary extract, lavender extract, carob extract (Ceratonia siliqua), calluna extract (Calluna vulgaris) and black seed extract (Nigella sativa) as active ingredients,
With respect to 100 parts by weight of the rose geranium extract, 100 parts by weight of the rosemary extract, 100 parts by weight of the lavender extract, 20 to 40 parts by weight of the carob extract, 20 to 40 parts by weight of the caluna extract, and the black sesame seeds As comprising the extract in an amount of 20 to 40 parts by weight,
Excellent EEG control effect through olfactory stimulation
perfume composition. The method of claim 1,
The EEG control effect is to decrease the beta wave (Beta (β) wave) and increase the alpha wave (Alpha (α) wave)
perfume composition. delete The method of claim 1,
The extract is extracted using an extraction solvent selected from the group consisting of water, C ₁ to C ₆ lower alcohols and mixtures thereof.
perfume composition. The method of claim 1,
The fragrance composition is excellent in concentration enhancement, mental and physical stability and stress relief effect
perfume composition. Claims 1, 2, 4, 5 comprising the perfume composition according to any one of claims
home care products. Claims 1, 2, 4, 5 comprising the perfume composition according to any one of claims
personal care products.

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