KR20140082699A - 플라빈 아데닌 디뉴클레오티드 또는 그의 염을 유효 성분으로서 함유하는 각막상피세포사의 억제제 - Google Patents
플라빈 아데닌 디뉴클레오티드 또는 그의 염을 유효 성분으로서 함유하는 각막상피세포사의 억제제 Download PDFInfo
- Publication number
- KR20140082699A KR20140082699A KR1020147009783A KR20147009783A KR20140082699A KR 20140082699 A KR20140082699 A KR 20140082699A KR 1020147009783 A KR1020147009783 A KR 1020147009783A KR 20147009783 A KR20147009783 A KR 20147009783A KR 20140082699 A KR20140082699 A KR 20140082699A
- Authority
- KR
- South Korea
- Prior art keywords
- corneal epithelial
- cell death
- epithelial cell
- salt
- adenine dinucleotide
- Prior art date
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JPJP-P-2011-210875 | 2011-09-27 | ||
JP2011210875 | 2011-09-27 | ||
PCT/JP2012/074662 WO2013047567A1 (ja) | 2011-09-27 | 2012-09-26 | フラビンアデニンジヌクレオチドまたはその塩を有効成分として含有する角膜上皮細胞死の抑制剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20140082699A true KR20140082699A (ko) | 2014-07-02 |
Family
ID=47995597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020147009783A KR20140082699A (ko) | 2011-09-27 | 2012-09-26 | 플라빈 아데닌 디뉴클레오티드 또는 그의 염을 유효 성분으로서 함유하는 각막상피세포사의 억제제 |
Country Status (8)
Country | Link |
---|---|
JP (1) | JP5969872B2 (el) |
KR (1) | KR20140082699A (el) |
CN (1) | CN103826642B (el) |
IN (1) | IN2014DN03350A (el) |
MY (1) | MY185239A (el) |
SG (2) | SG10201602401PA (el) |
TW (1) | TWI561238B (el) |
WO (1) | WO2013047567A1 (el) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016046734A2 (en) * | 2014-09-22 | 2016-03-31 | University Of The Western Cape | Compounds and compositions for treatment of tuberculosis |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2773076B1 (fr) * | 1997-12-29 | 2000-05-19 | Chauvin Lab Sa | Utilisation de la flavine-adenine-dinucleotide pour la preparation de compositions ophtalmiques utiles pour le traitement de l'oeil sec |
JP4836401B2 (ja) * | 2002-04-01 | 2011-12-14 | ロート製薬株式会社 | 眼科用組成物 |
JP2004203836A (ja) * | 2002-12-26 | 2004-07-22 | Rohto Pharmaceut Co Ltd | 眼科用局所適用製剤 |
JP2005239622A (ja) * | 2004-02-26 | 2005-09-08 | Rohto Pharmaceut Co Ltd | 角膜障害治療剤 |
JP4999304B2 (ja) * | 2004-09-27 | 2012-08-15 | ロート製薬株式会社 | ヒアルロン酸又はその塩を含有する粘膜適用組成物 |
JP4969052B2 (ja) * | 2005-03-31 | 2012-07-04 | 小林製薬株式会社 | 眼科用組成物 |
CN101301305A (zh) * | 2008-05-14 | 2008-11-12 | 北京润德康医药技术有限公司 | 一种黄素腺嘌呤二核苷酸二钠冻干粉针制剂及其制备方法 |
JP5506357B2 (ja) * | 2009-12-02 | 2014-05-28 | ロート製薬株式会社 | シリコーンハイドロゲルコンタクトレンズ用眼科組成物 |
EP2735303A1 (en) * | 2012-11-23 | 2014-05-28 | Pilosciences | Hair growth compositions and methods |
-
2012
- 2012-09-26 MY MYPI2014000895A patent/MY185239A/en unknown
- 2012-09-26 TW TW101135280A patent/TWI561238B/zh not_active IP Right Cessation
- 2012-09-26 KR KR1020147009783A patent/KR20140082699A/ko not_active Application Discontinuation
- 2012-09-26 WO PCT/JP2012/074662 patent/WO2013047567A1/ja active Application Filing
- 2012-09-26 SG SG10201602401PA patent/SG10201602401PA/en unknown
- 2012-09-26 JP JP2012212575A patent/JP5969872B2/ja active Active
- 2012-09-26 CN CN201280046826.0A patent/CN103826642B/zh not_active Expired - Fee Related
- 2012-09-26 SG SG11201400947XA patent/SG11201400947XA/en unknown
-
2014
- 2014-04-25 IN IN3350DEN2014 patent/IN2014DN03350A/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG10201602401PA (en) | 2016-04-28 |
JP2013082696A (ja) | 2013-05-09 |
SG11201400947XA (en) | 2014-07-30 |
TW201318628A (zh) | 2013-05-16 |
MY185239A (en) | 2021-04-30 |
CN103826642B (zh) | 2016-02-17 |
TWI561238B (en) | 2016-12-11 |
JP5969872B2 (ja) | 2016-08-17 |
CN103826642A (zh) | 2014-05-28 |
IN2014DN03350A (el) | 2015-06-05 |
WO2013047567A1 (ja) | 2013-04-04 |
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