SG10201602401PA - Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient - Google Patents

Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient

Info

Publication number
SG10201602401PA
SG10201602401PA SG10201602401PA SG10201602401PA SG10201602401PA SG 10201602401P A SG10201602401P A SG 10201602401PA SG 10201602401P A SG10201602401P A SG 10201602401PA SG 10201602401P A SG10201602401P A SG 10201602401PA SG 10201602401P A SG10201602401P A SG 10201602401PA
Authority
SG
Singapore
Prior art keywords
salt
active ingredient
cell death
epithelial cell
adenine dinucleotide
Prior art date
Application number
SG10201602401PA
Inventor
Asuka Sakamoto
Masatsugu Nakamura
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of SG10201602401PA publication Critical patent/SG10201602401PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG10201602401PA 2011-09-27 2012-09-26 Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient SG10201602401PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011210875 2011-09-27

Publications (1)

Publication Number Publication Date
SG10201602401PA true SG10201602401PA (en) 2016-04-28

Family

ID=47995597

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602401PA SG10201602401PA (en) 2011-09-27 2012-09-26 Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient
SG11201400947XA SG11201400947XA (en) 2011-09-27 2012-09-26 Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201400947XA SG11201400947XA (en) 2011-09-27 2012-09-26 Corneal epithelial cell death inhibitor containing flavin adenine dinucleotide or salt thereof as active ingredient

Country Status (8)

Country Link
JP (1) JP5969872B2 (en)
KR (1) KR20140082699A (en)
CN (1) CN103826642B (en)
IN (1) IN2014DN03350A (en)
MY (1) MY185239A (en)
SG (2) SG10201602401PA (en)
TW (1) TWI561238B (en)
WO (1) WO2013047567A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016046734A2 (en) * 2014-09-22 2016-03-31 University Of The Western Cape Compounds and compositions for treatment of tuberculosis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2773076B1 (en) * 1997-12-29 2000-05-19 Chauvin Lab Sa USE OF FLAVIN-ADENIN-DINUCLEOTIDE FOR THE PREPARATION OF OPHTHALMIC COMPOSITIONS USEFUL FOR THE TREATMENT OF DRY EYE
JP4836401B2 (en) * 2002-04-01 2011-12-14 ロート製薬株式会社 Ophthalmic composition
JP2004203836A (en) * 2002-12-26 2004-07-22 Rohto Pharmaceut Co Ltd Ophthalmic preparation for topical application
JP2005239622A (en) * 2004-02-26 2005-09-08 Rohto Pharmaceut Co Ltd Therapeutic agent for corneal disorder
JP4999304B2 (en) * 2004-09-27 2012-08-15 ロート製薬株式会社 Mucosal composition containing hyaluronic acid or a salt thereof
JP4969052B2 (en) * 2005-03-31 2012-07-04 小林製薬株式会社 Ophthalmic composition
CN101301305A (en) * 2008-05-14 2008-11-12 北京润德康医药技术有限公司 Flavin adenine dinucleotide disodium salt freeze-dried powder needle preparation and preparation thereof
JP5506357B2 (en) * 2009-12-02 2014-05-28 ロート製薬株式会社 Ophthalmic composition for silicone hydrogel contact lens
EP2735303A1 (en) * 2012-11-23 2014-05-28 Pilosciences Hair growth compositions and methods

Also Published As

Publication number Publication date
JP2013082696A (en) 2013-05-09
SG11201400947XA (en) 2014-07-30
TW201318628A (en) 2013-05-16
MY185239A (en) 2021-04-30
CN103826642B (en) 2016-02-17
TWI561238B (en) 2016-12-11
JP5969872B2 (en) 2016-08-17
CN103826642A (en) 2014-05-28
IN2014DN03350A (en) 2015-06-05
WO2013047567A1 (en) 2013-04-04
KR20140082699A (en) 2014-07-02

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