KR20140034193A - 가와사키병의 진단 마커 및 치료 표적 - Google Patents

가와사키병의 진단 마커 및 치료 표적 Download PDF

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Publication number
KR20140034193A
KR20140034193A KR1020137030334A KR20137030334A KR20140034193A KR 20140034193 A KR20140034193 A KR 20140034193A KR 1020137030334 A KR1020137030334 A KR 1020137030334A KR 20137030334 A KR20137030334 A KR 20137030334A KR 20140034193 A KR20140034193 A KR 20140034193A
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South Korea
Prior art keywords
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biomarker
biomarkers
subject
philamine
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KR1020137030334A
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English (en)
Korean (ko)
Inventor
알렉스 켄트시스
수잔 킴
하노 스틴
Original Assignee
칠드런'즈 메디컬 센터 코포레이션
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Publication of KR20140034193A publication Critical patent/KR20140034193A/ko
Withdrawn legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/328—Vasculitis, i.e. inflammation of blood vessels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020137030334A 2011-04-15 2012-04-13 가와사키병의 진단 마커 및 치료 표적 Withdrawn KR20140034193A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161475936P 2011-04-15 2011-04-15
US61/475,936 2011-04-15
US201161579007P 2011-12-22 2011-12-22
US61/579,007 2011-12-22
PCT/US2012/033514 WO2012142409A2 (en) 2011-04-15 2012-04-13 Diagnostic markers and therapeutic targets of kawasaki disease

Publications (1)

Publication Number Publication Date
KR20140034193A true KR20140034193A (ko) 2014-03-19

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ID=46208753

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137030334A Withdrawn KR20140034193A (ko) 2011-04-15 2012-04-13 가와사키병의 진단 마커 및 치료 표적

Country Status (8)

Country Link
US (1) US9869673B2 (cg-RX-API-DMAC10.html)
EP (2) EP3086121A1 (cg-RX-API-DMAC10.html)
JP (1) JP6072768B2 (cg-RX-API-DMAC10.html)
KR (1) KR20140034193A (cg-RX-API-DMAC10.html)
CN (2) CN106053835A (cg-RX-API-DMAC10.html)
AU (1) AU2012242684B2 (cg-RX-API-DMAC10.html)
CA (1) CA2833257A1 (cg-RX-API-DMAC10.html)
WO (1) WO2012142409A2 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230166380A (ko) * 2022-05-30 2023-12-07 충남대학교산학협력단 가와사키병 진단 및 불응성 가와사키병의 감별 진단을 위한 정보 제공 방법

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015168602A2 (en) * 2014-05-02 2015-11-05 Momenta Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of kawasaki disease
JP6779200B2 (ja) * 2014-07-24 2020-11-04 アカデミア シニカ 川崎病の診断及び治療
KR102056405B1 (ko) 2018-04-05 2019-12-16 (주)메디젠휴먼케어 Ebf2 유전자 다형성을 이용한 가와사키병 발병 예측 방법
CN110763845B (zh) * 2018-07-27 2022-10-28 成都市第三人民医院 一种检测蛋白标志物的配体在制备用于诊断结肠癌的产品中的用途和试剂盒
TWI704349B (zh) * 2019-06-17 2020-09-11 高雄榮民總醫院 蛋白質生物標記用以診斷川崎症的用途
US20230358762A1 (en) * 2020-09-16 2023-11-09 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Diagnostic methods for kawasaki disease
CN114556105A (zh) * 2020-10-02 2022-05-27 国际宇宙医疗株式会社 利用血中外泌体的蛋白质标志物的covid-19重症化预测方法
CN116087519B (zh) * 2021-05-17 2025-03-14 郑州大学第一附属医院 一种用于高危人群贲门腺癌早期筛查的标志物及其应用

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US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US7429466B2 (en) 2000-01-24 2008-09-30 Hypromatrix, Inc Methods and arrays for detecting biological molecules
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7112408B2 (en) 2001-06-08 2006-09-26 The Brigham And Women's Hospital, Inc. Detection of ovarian cancer based upon alpha-haptoglobin levels
US20030013208A1 (en) 2001-07-13 2003-01-16 Milagen, Inc. Information enhanced antibody arrays
WO2007003594A1 (en) * 2005-07-01 2007-01-11 Solvay Pharmaceuticals Gmbh Screening methods for inhibitors of the metalloprotease meprin
JP4795037B2 (ja) 2006-02-01 2011-10-19 財団法人 神戸市地域医療振興財団 川崎病の判定方法及びそのためのキット
EP2180320A1 (en) 2006-06-05 2010-04-28 Shimadzu Corporation Tumor marker and method for determination of the occurence of cancerous disease
CA2660286A1 (en) * 2006-08-09 2008-02-21 Homestead Clinical Corporation Organ-specific proteins and methods of their use
WO2009046267A1 (en) 2007-10-05 2009-04-09 University Of Virginia Patent Foundation Protein-based biomarkers for abdominal aortic aneurysm
US20110311443A1 (en) * 2009-03-06 2011-12-22 Klaus Tschira Stiftung Ggmbh Pharmaceutical composition and method for identifying a cancerous and/or an inflammatory disease in a patient

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230166380A (ko) * 2022-05-30 2023-12-07 충남대학교산학협력단 가와사키병 진단 및 불응성 가와사키병의 감별 진단을 위한 정보 제공 방법

Also Published As

Publication number Publication date
EP3086121A1 (en) 2016-10-26
AU2012242684A1 (en) 2013-10-31
CN103562725B (zh) 2016-08-17
WO2012142409A3 (en) 2013-02-28
WO2012142409A2 (en) 2012-10-18
CN103562725A (zh) 2014-02-05
US20140161791A1 (en) 2014-06-12
JP6072768B2 (ja) 2017-02-01
CN106053835A (zh) 2016-10-26
AU2012242684B2 (en) 2017-04-20
CA2833257A1 (en) 2012-10-18
EP2697653A2 (en) 2014-02-19
US9869673B2 (en) 2018-01-16
EP2697653B1 (en) 2016-03-30
JP2014512014A (ja) 2014-05-19

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Date Code Title Description
PA0105 International application

Patent event date: 20131115

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid