KR20120130758A - 수용체 티로신 키나제 (ｒｔｋ)의 억제제 및 그의 사용 방법 - Google Patents
수용체 티로신 키나제 (ｒｔｋ)의 억제제 및 그의 사용 방법 Download PDFInfo
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- KR20120130758A KR20120130758A KR1020127021221A KR20127021221A KR20120130758A KR 20120130758 A KR20120130758 A KR 20120130758A KR 1020127021221 A KR1020127021221 A KR 1020127021221A KR 20127021221 A KR20127021221 A KR 20127021221A KR 20120130758 A KR20120130758 A KR 20120130758A
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
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- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
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| US61/335,950 | 2010-01-14 | ||
| PCT/US2011/021109 WO2011088196A2 (en) | 2010-01-14 | 2011-01-13 | Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof |
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| KR20120130758A true KR20120130758A (ko) | 2012-12-03 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EA200901646A1 (ru) | 2007-06-05 | 2010-08-30 | Йел Юниверсити | Ингибиторы рецепторных тирозинкиназ и их применение |
| DK2668210T3 (da) | 2011-01-26 | 2020-08-24 | Celldex Therapeutics Inc | Anti-kit antistoffer og anvendelser deraf |
| CN110256559B (zh) | 2012-07-25 | 2023-05-26 | 塞尔德克斯医疗公司 | 抗kit抗体及其用途 |
| CA2898415A1 (en) | 2013-01-16 | 2014-07-24 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | A soluble fibroblast growth factor receptor 3 (fgr3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders |
| WO2014201034A2 (en) * | 2013-06-10 | 2014-12-18 | Ansun Biopharma, Inc. | Treatment for polyomavirus infection |
| ME03476B (me) | 2013-08-01 | 2020-01-20 | Five Prime Therapeutics Inc | Nefukozilisana anti-fgfr2iiib antitijela |
| WO2015057963A1 (en) | 2013-10-18 | 2015-04-23 | Eisai R&D Management Co., Ltd. | Fgfr4 inhibitors |
| CN113908269A (zh) | 2014-05-23 | 2022-01-11 | 塞尔德克斯医疗公司 | 嗜酸性粒细胞或肥大细胞相关病症的治疗 |
| JP6431622B2 (ja) | 2015-04-14 | 2018-11-28 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 結晶性ｆｇｆｒ４阻害剤化合物およびその使用 |
| KR20250034528A (ko) | 2015-11-23 | 2025-03-11 | 파이브 프라임 테라퓨틱스, 인크. | 암 치료에서의 단독의, 또는 면역 자극제와 병용한, fgfr2 억제제 |
| JP7372740B2 (ja) | 2016-05-10 | 2023-11-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 細胞生存性及び／又は細胞増殖を低減するための薬物の組み合わせ |
| CN110218712B (zh) * | 2016-06-02 | 2021-08-03 | 天津科技大学 | 磷脂酶d突变体及其在制备磷脂酸、磷脂酰丝氨酸中的应用 |
| PL3481859T3 (pl) | 2016-07-07 | 2022-07-11 | Pfizer Inc. | Rozpuszczalne polipeptydy receptora 3 czynnika wzrostu fibroblastów (sfgfr3) i ich zastosowania |
| PT3624837T (pt) | 2017-05-16 | 2025-10-01 | Five Prime Therapeutics Inc | Anticorpos anti-fgfr2 em combinação com agentes quimioterapêuticos no tratamento do cancro |
| JP2023538098A (ja) | 2020-08-21 | 2023-09-06 | ジェンザイム・コーポレーション | Ｆｇｆｒ３抗体および使用の方法 |
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| US8426396B2 (en) * | 2008-01-08 | 2013-04-23 | Shriners Hospitals For Children | Treatment for achondroplasia |
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- 2011-01-13 MX MX2012008222A patent/MX2012008222A/es not_active Application Discontinuation
- 2011-01-13 CA CA2786276A patent/CA2786276A1/en not_active Abandoned
- 2011-01-13 AU AU2011205297A patent/AU2011205297A1/en not_active Abandoned
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- 2011-01-13 CN CN2011800061813A patent/CN102762221A/zh active Pending
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- 2011-01-13 US US13/519,837 patent/US20120328599A1/en not_active Abandoned
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- 2011-01-13 SG SG2012045803A patent/SG181850A1/en unknown
- 2011-01-13 IN IN5017DEN2012 patent/IN2012DN05017A/en unknown
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Also Published As
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| IN2012DN05017A (enExample) | 2015-10-02 |
| RU2012134637A (ru) | 2014-02-20 |
| US20120328599A1 (en) | 2012-12-27 |
| WO2011088196A3 (en) | 2011-11-17 |
| SG181850A1 (en) | 2012-08-30 |
| BR112012016992A2 (pt) | 2019-09-24 |
| CN102762221A (zh) | 2012-10-31 |
| IL220206A0 (en) | 2012-07-31 |
| EP2523679A4 (en) | 2013-07-24 |
| CA2786276A1 (en) | 2011-07-21 |
| MX2012008222A (es) | 2012-08-17 |
| AU2011205297A1 (en) | 2012-06-28 |
| WO2011088196A2 (en) | 2011-07-21 |
| JP2013517282A (ja) | 2013-05-16 |
| EP2523679A2 (en) | 2012-11-21 |
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