CA2786276A1 - Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof - Google Patents
Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof Download PDFInfo
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- CA2786276A1 CA2786276A1 CA2786276A CA2786276A CA2786276A1 CA 2786276 A1 CA2786276 A1 CA 2786276A1 CA 2786276 A CA2786276 A CA 2786276A CA 2786276 A CA2786276 A CA 2786276A CA 2786276 A1 CA2786276 A1 CA 2786276A1
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33595010P | 2010-01-14 | 2010-01-14 | |
| US61/335,950 | 2010-01-14 | ||
| PCT/US2011/021109 WO2011088196A2 (en) | 2010-01-14 | 2011-01-13 | Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2786276A1 true CA2786276A1 (en) | 2011-07-21 |
Family
ID=44304965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2786276A Abandoned CA2786276A1 (en) | 2010-01-14 | 2011-01-13 | Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120328599A1 (enExample) |
| EP (1) | EP2523679A4 (enExample) |
| JP (1) | JP2013517282A (enExample) |
| KR (1) | KR20120130758A (enExample) |
| CN (1) | CN102762221A (enExample) |
| AU (1) | AU2011205297A1 (enExample) |
| BR (1) | BR112012016992A2 (enExample) |
| CA (1) | CA2786276A1 (enExample) |
| IL (1) | IL220206A0 (enExample) |
| IN (1) | IN2012DN05017A (enExample) |
| MX (1) | MX2012008222A (enExample) |
| RU (1) | RU2012134637A (enExample) |
| SG (1) | SG181850A1 (enExample) |
| WO (1) | WO2011088196A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2155238B1 (en) | 2007-06-05 | 2016-04-06 | Yale University | Antibody against d4 domain of the kit receptor and use thereor |
| AR085091A1 (es) | 2011-01-26 | 2013-09-11 | Kolltan Pharmaceuticals Inc | Anticuerpos anti-kit y sus usos |
| SG11201500489YA (en) | 2012-07-25 | 2015-02-27 | Kolltan Pharmaceuticals Inc | Anti-kit antibodies and uses thereof |
| EA201591324A1 (ru) | 2013-01-16 | 2016-01-29 | Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль) | Полипептид растворимого рецептора 3 фактора роста фибробластов (fgr3) для применения с целью предотвращения или лечения нарушений, связанных с замедлением роста скелета |
| WO2014201034A2 (en) * | 2013-06-10 | 2014-12-18 | Ansun Biopharma, Inc. | Treatment for polyomavirus infection |
| PE20160190A1 (es) | 2013-08-01 | 2016-04-28 | Five Prime Therapeutics Inc | Anticuerpos anti-fgfr2iiib afucosilados |
| CN110354128A (zh) | 2013-10-18 | 2019-10-22 | 卫材R&D管理有限公司 | 嘧啶fgfr4抑制剂 |
| CN106659782B (zh) | 2014-05-23 | 2021-11-09 | 塞尔德克斯医疗公司 | 一种用于嗜酸性粒细胞或肥大细胞相关病症治疗的抗体 |
| CA2982562C (en) | 2015-04-14 | 2023-06-13 | Eisai R&D Management Co., Ltd. | Crystalline fgfr4 inhibitor compound and uses thereof |
| BR112018010410A8 (pt) | 2015-11-23 | 2019-02-26 | Five Prime Therapeutics Inc | método para tratar câncer em um sujeito, composição e métodos de aumento do número de células nk e de aumento do número de uma ou mais células positivas para pd-l1 |
| JP7372740B2 (ja) | 2016-05-10 | 2023-11-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 細胞生存性及び／又は細胞増殖を低減するための薬物の組み合わせ |
| CN106085984B (zh) * | 2016-06-02 | 2019-07-19 | 天津科技大学 | 一种新型磷脂酶d及其制备磷脂酸、磷脂酰丝氨酸的方法 |
| RU2751483C2 (ru) | 2016-07-07 | 2021-07-14 | Пфайзер Инк. | Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения |
| CN110621336B (zh) | 2017-05-16 | 2024-05-14 | 戊瑞治疗有限公司 | 癌症治疗中抗fgfr2抗体与化学治疗剂的组合 |
| EP4200019A1 (en) | 2020-08-21 | 2023-06-28 | Genzyme Corporation | Fgfr3 antibodies and methods of use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426396B2 (en) * | 2008-01-08 | 2013-04-23 | Shriners Hospitals For Children | Treatment for achondroplasia |
-
2011
- 2011-01-13 WO PCT/US2011/021109 patent/WO2011088196A2/en not_active Ceased
- 2011-01-13 RU RU2012134637/10A patent/RU2012134637A/ru not_active Application Discontinuation
- 2011-01-13 IN IN5017DEN2012 patent/IN2012DN05017A/en unknown
- 2011-01-13 BR BR112012016992A patent/BR112012016992A2/pt not_active IP Right Cessation
- 2011-01-13 SG SG2012045803A patent/SG181850A1/en unknown
- 2011-01-13 US US13/519,837 patent/US20120328599A1/en not_active Abandoned
- 2011-01-13 CA CA2786276A patent/CA2786276A1/en not_active Abandoned
- 2011-01-13 KR KR1020127021221A patent/KR20120130758A/ko not_active Withdrawn
- 2011-01-13 JP JP2012549070A patent/JP2013517282A/ja not_active Withdrawn
- 2011-01-13 MX MX2012008222A patent/MX2012008222A/es not_active Application Discontinuation
- 2011-01-13 AU AU2011205297A patent/AU2011205297A1/en not_active Abandoned
- 2011-01-13 EP EP11733365.8A patent/EP2523679A4/en not_active Withdrawn
- 2011-01-13 CN CN2011800061813A patent/CN102762221A/zh active Pending
-
2012
- 2012-06-06 IL IL220206A patent/IL220206A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2523679A4 (en) | 2013-07-24 |
| MX2012008222A (es) | 2012-08-17 |
| BR112012016992A2 (pt) | 2019-09-24 |
| RU2012134637A (ru) | 2014-02-20 |
| IL220206A0 (en) | 2012-07-31 |
| EP2523679A2 (en) | 2012-11-21 |
| KR20120130758A (ko) | 2012-12-03 |
| IN2012DN05017A (enExample) | 2015-10-02 |
| JP2013517282A (ja) | 2013-05-16 |
| US20120328599A1 (en) | 2012-12-27 |
| AU2011205297A1 (en) | 2012-06-28 |
| CN102762221A (zh) | 2012-10-31 |
| WO2011088196A2 (en) | 2011-07-21 |
| WO2011088196A3 (en) | 2011-11-17 |
| SG181850A1 (en) | 2012-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20150113 |