KR20110043654A - 폰 빌레브란트 인자 또는 제ⅷ 인자 및 혈소판의 억제제에 의하여 유도된 응고장애 치료용 폰 빌레브란트 인자 - Google Patents
폰 빌레브란트 인자 또는 제ⅷ 인자 및 혈소판의 억제제에 의하여 유도된 응고장애 치료용 폰 빌레브란트 인자 Download PDFInfo
- Publication number
- KR20110043654A KR20110043654A KR1020117002934A KR20117002934A KR20110043654A KR 20110043654 A KR20110043654 A KR 20110043654A KR 1020117002934 A KR1020117002934 A KR 1020117002934A KR 20117002934 A KR20117002934 A KR 20117002934A KR 20110043654 A KR20110043654 A KR 20110043654A
- Authority
- KR
- South Korea
- Prior art keywords
- vwf
- fviii
- factor
- platelet
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008032361A DE102008032361A1 (de) | 2008-07-10 | 2008-07-10 | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
| DE102008032361.6 | 2008-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20110043654A true KR20110043654A (ko) | 2011-04-27 |
Family
ID=41171229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117002934A Ceased KR20110043654A (ko) | 2008-07-10 | 2009-07-10 | 폰 빌레브란트 인자 또는 제ⅷ 인자 및 혈소판의 억제제에 의하여 유도된 응고장애 치료용 폰 빌레브란트 인자 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8603979B2 (https=) |
| EP (1) | EP2310043B2 (https=) |
| JP (1) | JP5653916B2 (https=) |
| KR (1) | KR20110043654A (https=) |
| CN (1) | CN102088999A (https=) |
| AU (1) | AU2009268289B2 (https=) |
| CA (1) | CA2730290C (https=) |
| DE (1) | DE102008032361A1 (https=) |
| DK (1) | DK2310043T4 (https=) |
| ES (1) | ES2395855T5 (https=) |
| PL (1) | PL2310043T5 (https=) |
| RU (1) | RU2563236C2 (https=) |
| WO (1) | WO2010003687A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11197916B2 (en) | 2007-12-28 | 2021-12-14 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
| CN105816858B (zh) | 2007-12-28 | 2024-10-18 | 武田药品工业株式会社 | 重组vwf配方 |
| KR20160104740A (ko) * | 2008-06-24 | 2016-09-05 | 옥타파마 아게 | 응고 인자 viii을 정제하는 방법 |
| DE102008032361A1 (de) * | 2008-07-10 | 2010-01-21 | Csl Behring Gmbh | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
| EP2349314B1 (en) | 2008-10-21 | 2013-02-27 | Baxter International Inc. | Lyophilized recombinant vwf formulations |
| DK2804623T3 (da) | 2012-01-12 | 2019-11-11 | Bioverativ Therapeutics Inc | Kimære faktor viii-polypeptider og anvendelser deraf |
| JP2015515482A (ja) | 2012-04-24 | 2015-05-28 | ノヴォ ノルディスク アー/エス | 血友病の治療に適する化合物 |
| EP2662083A1 (en) | 2012-05-08 | 2013-11-13 | CSL Behring GmbH | Sugar compositions for treating hemophilia a and/or von willebrand disease |
| CN102776260B (zh) * | 2012-07-26 | 2015-04-29 | 上海泰龙生物医药科技有限公司 | 一种高效表达重组人凝血八因子的方法 |
| EP2796145B1 (en) | 2013-04-22 | 2017-11-01 | CSL Ltd. | A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge |
| CN103263663B (zh) * | 2013-06-08 | 2016-05-04 | 兆科药业(合肥)有限公司 | 一种抗血小板溶栓素在制备治疗vwf缺陷型血管栓塞性疾病的药物中的应用 |
| US10231993B2 (en) | 2013-06-27 | 2019-03-19 | University Of Washington Through Its Center For Commercialization | Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4430205A1 (de) | 1994-08-26 | 1996-02-29 | Behringwerke Ag | Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung |
| US6518482B2 (en) * | 1994-09-13 | 2003-02-11 | American National Red Cross | Transgenic non-human mammals expressing human coagulation factor VIII and von Willebrand factor |
| DE4437544A1 (de) * | 1994-10-20 | 1996-04-25 | Behringwerke Ag | Einsatz von vWF-enthaltenden Konzentraten als Kombinationstherapie bei Therapie mit Antithrombotika und Fibrinolytika |
| FR2744918B1 (fr) | 1996-02-19 | 1998-05-07 | Sanofi Sa | Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique |
| FI974321A0 (fi) * | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
| WO2001047547A1 (en) † | 1999-12-24 | 2001-07-05 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Medicinal compositions for preventing and treating hemorrhagic diseases associating thrombopathy |
| DE102008032361A1 (de) * | 2008-07-10 | 2010-01-21 | Csl Behring Gmbh | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
-
2008
- 2008-07-10 DE DE102008032361A patent/DE102008032361A1/de not_active Withdrawn
-
2009
- 2009-07-10 US US13/003,139 patent/US8603979B2/en active Active
- 2009-07-10 EP EP09777111.7A patent/EP2310043B2/en active Active
- 2009-07-10 WO PCT/EP2009/005027 patent/WO2010003687A1/en not_active Ceased
- 2009-07-10 AU AU2009268289A patent/AU2009268289B2/en active Active
- 2009-07-10 CN CN2009801264767A patent/CN102088999A/zh active Pending
- 2009-07-10 KR KR1020117002934A patent/KR20110043654A/ko not_active Ceased
- 2009-07-10 RU RU2011104705/15A patent/RU2563236C2/ru active
- 2009-07-10 ES ES09777111T patent/ES2395855T5/es active Active
- 2009-07-10 DK DK09777111.7T patent/DK2310043T4/da active
- 2009-07-10 CA CA2730290A patent/CA2730290C/en active Active
- 2009-07-10 PL PL09777111.7T patent/PL2310043T5/pl unknown
- 2009-07-10 JP JP2011517038A patent/JP5653916B2/ja active Active
-
2013
- 2013-11-04 US US14/071,193 patent/US9095564B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011527301A (ja) | 2011-10-27 |
| DE102008032361A1 (de) | 2010-01-21 |
| US20110112023A1 (en) | 2011-05-12 |
| EP2310043B2 (en) | 2022-05-18 |
| ES2395855T3 (es) | 2013-02-15 |
| US20140128325A1 (en) | 2014-05-08 |
| DK2310043T4 (da) | 2022-06-20 |
| RU2011104705A (ru) | 2012-08-20 |
| JP5653916B2 (ja) | 2015-01-14 |
| CA2730290C (en) | 2017-02-07 |
| AU2009268289B2 (en) | 2014-11-06 |
| US8603979B2 (en) | 2013-12-10 |
| PL2310043T5 (pl) | 2024-02-05 |
| PL2310043T3 (pl) | 2013-02-28 |
| RU2563236C2 (ru) | 2015-09-20 |
| CA2730290A1 (en) | 2010-01-14 |
| DK2310043T3 (da) | 2013-01-07 |
| CN102088999A (zh) | 2011-06-08 |
| EP2310043A1 (en) | 2011-04-20 |
| EP2310043B1 (en) | 2012-09-19 |
| US9095564B2 (en) | 2015-08-04 |
| WO2010003687A1 (en) | 2010-01-14 |
| AU2009268289A1 (en) | 2010-01-14 |
| ES2395855T5 (es) | 2022-09-06 |
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Legal Events
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| PA0105 | International application |
Patent event date: 20110208 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20140224 Comment text: Request for Examination of Application |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20150831 Patent event code: PE09021S01D |
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| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20160519 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20150831 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
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| A107 | Divisional application of patent | ||
| J201 | Request for trial against refusal decision | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20160818 |
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| PJ0201 | Trial against decision of rejection |
Patent event date: 20160818 Comment text: Request for Trial against Decision on Refusal Patent event code: PJ02012R01D Patent event date: 20160519 Comment text: Decision to Refuse Application Patent event code: PJ02011S01I Appeal kind category: Appeal against decision to decline refusal Decision date: 20161021 Appeal identifier: 2016101004838 Request date: 20160818 |
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| J801 | Dismissal of trial |
Free format text: TRIAL NUMBER: 2016101004838; REJECTION OF TRIAL FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20160818 Effective date: 20161021 |
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| PJ0801 | Rejection of trial |
Patent event date: 20161021 Patent event code: PJ08011S01D Comment text: Decision on Dismissal of Request for Trial (Dismissal of Decision) Decision date: 20161021 Appeal kind category: Appeal against decision to decline refusal Appeal identifier: 2016101004838 Request date: 20160818 |