KR20110017874A - 오래 작용하는 ｙ２ 및／또는 ｙ４ 수용체 작용제 - Google Patents

오래 작용하는 ｙ２ 및／또는 ｙ４ 수용체 작용제 Download PDF

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Publication number
KR20110017874A
KR20110017874A KR1020107027495A KR20107027495A KR20110017874A KR 20110017874 A KR20110017874 A KR 20110017874A KR 1020107027495 A KR1020107027495 A KR 1020107027495A KR 20107027495 A KR20107027495 A KR 20107027495A KR 20110017874 A KR20110017874 A KR 20110017874A
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KR
South Korea
Prior art keywords
ethoxy
xaa
seq
acid
acetylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020107027495A
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English (en)
Korean (ko)
Inventor
소렌 오스터가드
산네 몰러 크누드센
제인 스페츨러
라스무스 조르젠센
제이콥 코포이드
Original Assignee
노보 노르디스크 에이/에스
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Publication date
Application filed by 노보 노르디스크 에이/에스 filed Critical 노보 노르디스크 에이/에스
Publication of KR20110017874A publication Critical patent/KR20110017874A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020107027495A 2008-05-16 2009-05-18 오래 작용하는 ｙ２ 및／또는 ｙ４ 수용체 작용제 Withdrawn KR20110017874A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08156360 2008-05-16
EP08156360.3 2008-05-16
EP09154461 2009-03-05
EP09154461.9 2009-03-05

Publications (1)

Publication Number Publication Date
KR20110017874A true KR20110017874A (ko) 2011-02-22

Family

ID=40934036

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107027495A Withdrawn KR20110017874A (ko) 2008-05-16 2009-05-18 오래 작용하는 ｙ２ 및／또는 ｙ４ 수용체 작용제

Country Status (12)

Country Link
US (1) US20110275559A1 (https=)
EP (1) EP2279204A1 (https=)
JP (1) JP2011520847A (https=)
KR (1) KR20110017874A (https=)
CN (1) CN102027007A (https=)
AU (1) AU2009248041B2 (https=)
BR (1) BRPI0912615A2 (https=)
CA (1) CA2723855A1 (https=)
IL (1) IL208836A0 (https=)
MX (1) MX2010011845A (https=)
RU (1) RU2504550C2 (https=)
WO (1) WO2009138511A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9260500B2 (en) 2009-07-02 2016-02-16 Takeda Pharmaceutical Company Limited Peptide and use thereof
EP2477643A1 (en) * 2009-09-18 2012-07-25 Novo Nordisk A/S Long-acting y2 receptor agonists
WO2011058165A1 (en) * 2009-11-13 2011-05-19 Novo Nordisk A/S Long-acting y2 receptor agonists
GB201001333D0 (en) * 2010-01-27 2010-03-17 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
EP2600887A4 (en) 2010-07-09 2014-01-22 Amylin Pharmaceuticals Llc MICROCRYSTALLINE Y RECEPTOR AGONISTS
MX377589B (es) 2010-12-16 2025-03-10 Novo Nordisk As Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico.
CN104203266B (zh) 2012-03-22 2017-12-26 诺和诺德股份有限公司 Glp‑1肽组合物及其制备
JP6672140B2 (ja) 2013-05-02 2020-03-25 ノヴォ ノルディスク アー／エス Ｇｌｐ−１化合物の経口投薬
EP2842965A1 (en) 2013-09-03 2015-03-04 Gubra ApS Neuromedin U analogs comprising serum albumin binding amino acid residue
US10583172B2 (en) 2013-11-15 2020-03-10 Novo Nordisk A/S HPYY(1-36) having a beta-homoarginine substitution at position 35
WO2015073878A1 (en) * 2013-11-15 2015-05-21 Ur Diet, Llc Real-time satiety biofeedback
MX369818B (es) 2013-11-15 2019-11-22 Novo Nordisk As Compuestos selectivos de peptido yy (pyy) y usos de los mismos.
DK3068421T3 (da) * 2013-11-15 2019-06-24 Novo Nordisk As Selektive pyy-forbindelser og anvendelser deraf
US20240100450A9 (en) * 2014-01-17 2024-03-28 Repligen Corporation Sterilizing chromatography columns
US10610807B2 (en) 2014-01-17 2020-04-07 Repligen Corporation Sterilizing chromatography columns
CN114805527A (zh) * 2014-05-21 2022-07-29 哈佛大学的校长及成员们 Ras抑制肽和其用途
MA43205A (fr) 2015-06-12 2018-09-19 Novo Nordisk As Composés pyy sélectifs et leurs utilisations
PL3746111T3 (pl) 2018-02-02 2024-01-15 Novo Nordisk A/S Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową
TWI749381B (zh) * 2018-11-01 2021-12-11 美商美國禮來大藥廠 蛋白質酪胺酸-酪胺酸類似物及其使用方法
GB201908426D0 (en) * 2019-06-12 2019-07-24 Imp College Innovations Ltd Appetite suppressing compounds
AU2021257477A1 (en) * 2020-04-17 2022-12-08 I2O Therapeutics, Inc. Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use
CA3215858A1 (en) 2021-04-27 2022-11-03 Zhenhuan ZHENG Combination of bitter receptor agonist and gut-signaling compound

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8273713B2 (en) * 2000-12-14 2012-09-25 Amylin Pharmaceuticals, Llc Methods of treating obesity using PYY[3-36]
KR101241862B1 (ko) * 2003-09-19 2013-03-13 노보 노르디스크 에이/에스 신규 ｇｌｐ-1 유도체
WO2005077094A2 (en) * 2004-02-11 2005-08-25 Amylin Pharmaceuticals, Inc. Pancreatic polypeptide family motifs and polypeptides comprising the same
CA2560174A1 (en) * 2004-03-17 2005-09-29 7Tm Pharma A/S Y4 selective receptor agonists for therapeutic interventions
MXPA06015049A (es) * 2004-07-08 2007-02-08 Novo Nordisk As Marcadores prolongadores de polipeptidos que comprenden una porcion tetrazol.
AU2006271792A1 (en) * 2005-07-18 2007-01-25 Novo Nordisk A/S Peptides for use in the treatment of obesity

Also Published As

Publication number Publication date
MX2010011845A (es) 2010-11-22
BRPI0912615A2 (pt) 2016-01-26
CA2723855A1 (en) 2009-11-19
EP2279204A1 (en) 2011-02-02
RU2010149474A (ru) 2012-06-27
RU2504550C2 (ru) 2014-01-20
WO2009138511A1 (en) 2009-11-19
JP2011520847A (ja) 2011-07-21
CN102027007A (zh) 2011-04-20
AU2009248041B2 (en) 2013-10-03
IL208836A0 (en) 2011-01-31
AU2009248041A1 (en) 2009-11-19
US20110275559A1 (en) 2011-11-10

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Patent event date: 20101207

Patent event code: PA01051R01D

Comment text: International Patent Application

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A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20140516

Comment text: Request for Examination of Application

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Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20141006

WITB Written withdrawal of application