KR20100065387A - 아제티디논 제조를 위한 케토리덕타제 폴리펩티드 - Google Patents

아제티디논 제조를 위한 케토리덕타제 폴리펩티드 Download PDF

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KR20100065387A
KR20100065387A KR1020107008910A KR20107008910A KR20100065387A KR 20100065387 A KR20100065387 A KR 20100065387A KR 1020107008910 A KR1020107008910 A KR 1020107008910A KR 20107008910 A KR20107008910 A KR 20107008910A KR 20100065387 A KR20100065387 A KR 20100065387A
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residues
residue
amino acid
polypeptide
nonpolar
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오노라토 캄파피아노
에밀리 문도르프
버스 보럽
라마 볼라드리
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코덱시스, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01184—Carbonyl reductase (NADPH) (1.1.1.184)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020107008910A 2007-10-01 2008-10-01 아제티디논 제조를 위한 케토리덕타제 폴리펩티드 Withdrawn KR20100065387A (ko)

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US97655507P 2007-10-01 2007-10-01
US60/976,555 2007-10-01

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KR20100065387A true KR20100065387A (ko) 2010-06-16

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US (14) US7883879B2 (https=)
EP (1) EP2205727B1 (https=)
JP (1) JP5646328B2 (https=)
KR (1) KR20100065387A (https=)
CN (1) CN101883846A (https=)
ES (1) ES2547528T3 (https=)
HU (1) HUE027683T2 (https=)
IL (2) IL204379A (https=)
SI (1) SI2205727T1 (https=)
WO (1) WO2009046153A1 (https=)

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WO2009046153A4 (en) 2009-06-25
US9719071B2 (en) 2017-08-01
US8980606B2 (en) 2015-03-17
US12421503B2 (en) 2025-09-23
US10597641B2 (en) 2020-03-24
ES2547528T3 (es) 2015-10-07
IL232707A0 (en) 2014-07-31
US10329540B2 (en) 2019-06-25
US20130034895A1 (en) 2013-02-07
US20110159567A1 (en) 2011-06-30
US9133442B2 (en) 2015-09-15
JP5646328B2 (ja) 2014-12-24
US9476034B2 (en) 2016-10-25
HUE027683T2 (en) 2016-10-28
US20170313992A1 (en) 2017-11-02
US11078466B2 (en) 2021-08-03
JP2010539952A (ja) 2010-12-24
US20190256825A1 (en) 2019-08-22
IL204379A (en) 2014-06-30
US20170121689A1 (en) 2017-05-04
US20160281067A1 (en) 2016-09-29
US8257952B2 (en) 2012-09-04
US20150337271A1 (en) 2015-11-26
US20170002333A1 (en) 2017-01-05
EP2205727B1 (en) 2015-06-24
CN101883846A (zh) 2010-11-10
US9382519B2 (en) 2016-07-05
US20240141304A1 (en) 2024-05-02
US20210324347A1 (en) 2021-10-21
IL232707A (en) 2015-11-30
EP2205727A1 (en) 2010-07-14
US20090162909A1 (en) 2009-06-25
US8470572B2 (en) 2013-06-25
US20150197731A1 (en) 2015-07-16
US12049649B2 (en) 2024-07-30
SI2205727T1 (sl) 2015-09-30
US9580694B2 (en) 2017-02-28
US7883879B2 (en) 2011-02-08
US20200172880A1 (en) 2020-06-04
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