KR20100058866A - Scalp-care composition for enhanced scalp-safety and anti-dandruff effect - Google Patents

Abstract

PURPOSE: A cosmetic composition for anti-dandruff is provided to maintain pH concentration from 4.0 to 6.0 and to ensure safety to scalp. CONSTITUTION: A hair cosmetic composition for anti-dandruff contains 0.01-2.0 weight% of Zn-pyrithione of chemical formula 1 and 0.01-5.0 weight% of trihydroxystearin of chemical formula 2 as active ingredient. The acidity of the composition is maintained in pH 4.0-6.0. The pH adjusting agent is stearic acid citric acid, acetic acid, lactic acid, aspartic acid, or stearic acid. The hair cosmetic composition is used in the form of shampoo, rinse, hair tonic, or hair treatment.

Description

Scalp-care Composition for Enhanced Scalp-Safety and anti-dandruff effect

The present invention relates to an anti-dandruff hair cosmetic composition having improved scalp safety and anti-dandruff, and more specifically, for anti-dandruff using zinc pyrithione (Zn-Pyrithione) and trihydroxystearin as an active ingredient. It relates to a hair cosmetic composition.

Many people today suffer from increased stress, air and water pollution, itching, dandruff and hair loss. Some consumers who use traditional soaps or hair-cleaning shampoos to clean their hair and scalp are gradually increasing the number of people with scalp problems such as itching and dandruff caused by the use of the product. One of the attempts is to add additional ingredients such as anti-dandruff, antibacterial, scalp irritant, and anti-itch to the shampoo product. Various products for use before or after shampooing are being studied.

However, itching or dandruff are not necessarily symptoms of the same cause. People with dandruff almost always have itching, but itching does not necessarily have dandruff.

Dandruff can be divided into common dandruff, mild symptom, psoriasis with much peeling of scull, and seborrheic-dandruff, where sebum accumulates in the scalp along with excessive sebum secretion. Itching and dandruff originate from internal and external factors of the body, and in order to escape from itching and dandruff caused by these factors, anti-dandruff drugs, quasi-drugs, and cosmetics are used for skin treatment (Topical treatment).

Known anti-dandruff substances include Tar, Zinc-Pyrithione, Pirotone olamine, Sulfur, Selenium Sulfate, Selim 2, Climbazole, Salicylic acid, camphor, menthol, captan, allantoin, and corticosteroids.

The zinc-pyrithione has two extra covalent bonds with zinc (Zn) having two valence bonds with a sulfur (S) atom and two coordination bonds with an oxygen (O) atom. have. Zinc pyrithione (ZNP) is a white solid particle having a very high specific gravity of 1.782 at 25 ° C. and a neutral pH of 7.3 in a 5% aqueous solution.

In U.S. Pat. As a ligand, an aqueous solution of zinc pyrithione was prepared using amines such as diethanolamine and EDTA (Ethylenediaminetetraacetic acid) as a solvent. However, these solutions are stable only at pH 8.5 to 9.0, and when acid such as citric acid is added to neutralize the pH of the composition, the dissolved zinc pyrithione again forms an insoluble precipitate, which has disadvantages in product application. In addition, there are disadvantages of strong specific odor and skin irritation caused by amines used as ligands.

In general, the optimum pH for the normal functioning of the skin is known to be 5.0 or less, and after every cleaning action the pH temporarily rises and then returns to pH 5.0 or less ( International journal of cosmetics science 2006, 28, 359-). 370 ).

Therefore, there is a need to develop a low pH shampoo and a product with a bio-buffer function that enables a quick return to the skin's original pH after washing.

Accordingly, the present inventors can improve the safety of the scalp by additionally prescribing the liquid of the zinc pyrithione-containing shampoo with weak acidity while researching to improve the scalp safety of the anti-dandruff shampoo, and can additionally enhance the anti-dandruff power. The present invention was completed.

An object of the present invention relates to an anti-dandruff hair cosmetic composition with improved scalp safety and anti-dandruff, more specifically, zinc pyrithione (Zn-Pyrithione) and trihydroxystearin (Trihydroxystearin) as an active ingredient As a hair cosmetic composition for dandruff, by maintaining the pH of the composition at a weak acidity of 4.0 to 6.0 to improve the pH recovery rate of the scalp to provide an anti-dandruff hair cosmetic composition that provides improved safety for the scalp and improved dandruff effect. .

In order to achieve the above object, the present invention provides a zinc cosmetic composition for anti-dandruff containing zinc pyrithione and maintaining the pH of about 4.0 to 6.0 in weak acidity, thereby improving scalp safety and antidandruff.

 The present invention contains anti-dandruff to improve the stability of zinc pyrithione by containing a glyceryl-introduced triester wax to solve the stability inhibition of zinc pyrithione that may occur in the low pH region of zinc pyrithione It provides a hair cosmetic composition for.

Hereinafter, the present invention will be described in more detail.

The present invention relates to a scalp care composition that maintains the liquidity at a pH of 4.0 to 6.0 in the anti-dandruff composition containing zinc pyrithione to accelerate recovery to the natural pH of the scalp. In addition, the present invention relates to a composition in which glyceryl-introduced triester wax is introduced to improve the stability of zinc pyrithione in a weakly acidic composition.

Zinc pyrithione (Zinc pyrithione) used in the present invention is a kind of antibacterial agent and has an antifungal effect of inhibiting the growth of dandruff, and is represented by the following Chemical Formula 1.

It is added to most products, such as creams and gels, as well as shampoos, rinses and conditioners that are currently available on the market for dandruff and scalp itch.

In the present invention, it is preferable to contain zinc pyrithione in an amount of 0.01 to 2% by weight based on the total weight of the composition for the purpose of preventing dandruff, and when the content of zinc pyrithione is less than 0.01% by weight, the effect and effect are weak. If it exceeds 2% by weight, problems with formulation stabilization will occur.

In the present invention, citric acid (citric acid) was used to adjust the pH to weak acidity, and in addition to citric acid, organic acids such as acetic acid, lactic acid, aspartic acid, stearic acid, and the like may be used.

The glyceryl group-introduced triester wax used in the present invention is trihydroxystearin (Trihydroxystearin) was used to improve the stability of zinc pyrithione in the present composition and is represented by the following formula (2).

Trihydroxystearin is generally used as a skin conditioning material or as a viscosity forming material, but in addition to that purpose, trihydroxystearin was used in the present composition to improve the stability of zinc pyrithione at low pH.

In the present invention, it is preferable to contain 0.01 to 5% by weight relative to the total weight of the composition for the purpose of stabilizing zinc pyridion. More preferably, 0.1 to 1 weight% is contained. When the trihydroxystearin content is less than 0.01% by weight, the effect of stability is insignificant, and when it is 5% by weight or more, inhibition of use occurs.

 According to an embodiment of the present invention, the scalp care composition according to the present invention contains zinc pyrithione solution as an active ingredient and maintains the pH of the composition at 4.0 to 6.0. It also contains 0.01 to 5% by weight of trihydroxystearin to improve the stability of the composition.

The trihydroxystearin enables stable dispersion of the antidandruff component even at a weakly acidic pH, thereby improving both the safety of the scalp and the enhancement effect of the antidandruff.

According to an embodiment of the present invention, the scalp care composition according to the present invention may further contain an anionic surfactant, a cationic polymer and a conditioning component commonly used in the art.

Anionic surfactants used in the present invention include alkyl sulfates, ethoxylated alkyl sulfates, alkyl ethoxy carboxylates, alkyl glyceryl ether sulfonates, ethoxyether sulfonates, methyl acyl taurates, alkyl sulfosuccinates , Alkyl ethoxysulfosuccinates, alpha-sulfonated fatty acids, salts and / or esters thereof, alkyl phosphate esters, ethoxylated alkyl phosphate esters, straight chain alkyl benzene sulfonates, paraffin sulfonates, alpha olefin sulfonates, Alkyl alkoxysulfates and mixtures thereof, but is not limited thereto. The alkyl and / or acyl chain length of the surfactant may be C _12-18 , preferably C _12-14 . It is because it is difficult to use it because it is less than C <_{12> and since} it has a low foaming force, it exceeds _C18 . The content of the anionic surfactant may be 1 to 50% by weight, preferably 5 to 20% by weight based on the total weight of the composition. If the content of the anionic surfactant is less than 1% by weight, the cleaning power expected in the cleaning agent may not be exerted. If the content of the anionic surfactant is more than 50% by weight, it is not preferable because it causes irritation to the human body with excessive cleaning power.

Cationic polymers used in the present invention include, but are not limited to, polymeric quaternary ammonium salts of hydroxyethyl cellulose and guar hydroxypropyltriammonium chlorides. Cationic polymers have the effect of conditioning the hair, softening the surface of the hair, enhancing foaming and foaming. The content of the cationic polymer may be 0.1 to 1.0% by weight, preferably 0.1 to 0.5% by weight based on the total weight of the composition. When the content of the cationic polymer is less than 0.1% by weight, the above effect cannot be expected, and when the content of the cationic polymer exceeds 1.0% by weight, it is difficult to control the viscosity and excessively adheres to the hair, thereby significantly reducing the feeling of use.

Conditioning components used in the present invention include cyclomethicone, dimethicone (dimethyl polysiloxane), dimethicone copolyol, alkyl dimethicone copolyol, silicone ester, fluoro dimethicone, alkyl dimethicone, dimethicone copolyolamine, Silicones including carboxysilicon, silicone phosphate esters, silicone resins, silicone phospholipids, amodimethicone, aminopropyldimethicone and silicone quartz, but are not limited thereto. The content of the conditioning component may be 0.01 to 5.0% by weight, preferably 1.3 to 3.0% by weight based on the total weight of the composition. If the content of the conditioning component is less than 0.01% by weight, it is difficult to expect a conditioning effect, and when it exceeds 5.0% by weight, the quality deterioration due to destabilization of the formulation may be feared.

In addition, according to an embodiment of the present invention, the hair or scalp cosmetic composition according to the present invention further contains a pigment, preservative, metal ion sequestrant and fragrance, which are commonly used in the art, within a range of maintaining stability. can do.

Hair or scalp cosmetic composition according to an embodiment of the present invention may be a hair cleanser composition, hair shampoo, hair rinse, hair conditioner, hair treatment, hair tonic, scalp treatment, hair lotion, hair cream, hair nourishing lotion or general And the like.

The anti-dandruff hair cosmetic composition of the present invention enables stable dispersion of the anti-dandruff component even at pH 4.0 to 6.0, thereby quickly recovering to the natural pH of the scalp due to weak acidity, as well as improving the safety of the scalp and anti-dandruff. There is an advantage that all of the power enhancement effect can be obtained.

Hereinafter, the present invention will be described in more detail with respect to preferred embodiments and comparative examples of the hair or scalp cosmetic composition. However, the following embodiments are only preferred embodiments of the present invention, and the present invention is not limited to such embodiments.

[Examples and Comparative Examples]

To prepare a shampoo by mixing each component according to the composition shown in Table 1 below.

Test Example 1 Experiment on pH Restoration Rate in Skin

Nine healthy men and women were tested for pH recovery rate. The compositions of Comparative Examples 1, 1 and 2 were treated and tested, and the method was as follows. After waiting for 20 minutes in a constant temperature and humidity condition, measure the skin value before treatment using pH meter. After moistening the entire test site with water, 150 μl of each of Example 1, Example 2 and Comparative Example 1 (purified water) was dropped on the test site, rubbed 50 times, and rinsed with tap water for 30 seconds. After washing, the pH was measured after waiting for 20 minutes at a constant temperature and humidity conditions for 30 minutes. Measure pH at 1 hour, 2 hours, 4 hours, 6 hours after cleaning, but stabilize after exposure of the measurement site at constant temperature and humidity conditions for 20 minutes before measurement. The measured results are shown in Table 2 and FIG.

As can be seen in Table 2 and FIG. 1, the washing itself also raises the pH of the skin in the short term, and the higher the pH of the product, the higher the pH of the skin. After 30 minutes after washing, the pH of the skin was increased, and in Example 2 where the pH was lowered to 5.05, the restoration of skin pH with time was similar to that of water.

 Test Example 2 Anti Dandruff Force Experiment

In order to determine the dandruff reduction effect of Example 1, Examples 2 and 3 of Table 1 was used 'guinea pig skin disk manufacturing method and antimicrobial activity measurement method thereof' of Korean Patent Publication No. 1999-0061931. The measuring method is the method closest to the consumer's habit of use, by treating the skin of a guinea pig abdomen similar to human skin with a medicament to remove the dermis, etc. attached to the skin, and drying it, punching it to a constant thickness and size. It is a method of measuring the antimicrobial power closest to the actual use method of the consumer by using the prepared skin disk for measuring the antimicrobial power of the washoff product. After treating Example 1, Example 2, and Example 3 to the prepared skin discs, the experimental results are shown in Table 3 below as average values of the results of three measurements.

As can be seen from Table 3 and Figure 2, the present invention can be confirmed that in the case of Example 2 having the lowest pH, the inhibition zone of dandruff has a larger value than that of Example 1 having a pH of 6 or more.

Test Example 3 Dispersion Stability Experiment

To prepare a shampoo by mixing each component according to the composition shown in Table 4.

After preparing Comparative Example 2, Example 4, and Example 5, the dispersion stability was observed at low temperature, 30 degrees, 45 degrees, and room temperature. Ethylene glycol distearate contained in Comparative Example 2 is commonly used in the art as a role of dispersion stabilization in the formulation, in this test with trihydroxystearin in dispersion stabilization of zinc pyrithione. Used for comparison. After 7 days of observation, Comparative Example 2 visually observed a precipitate of zinc pyrithione at 45 degrees, and Examples 4 and 5 showed dispersion stability over one month at both low temperature, room temperature, and high temperature. As can be seen from this, when 0.1% by weight or more of trihydroxystearin was used, it was confirmed that the stability of zinc pyrithione was improved at low pH.

1 is a graph showing the pH recovery rate of the skin according to the scalp care shampoo of the present invention.

Figure 2 is a graph showing the anti-dandruff effect according to the scalp care shampoo of the present invention.

Claims (6)

An anti-dandruff hair cosmetic composition comprising zinc pyrithione of Formula 1 and trihydroxystearin of Formula 2 as an active ingredient.

The method of claim 1, The content of the zinc pyrithione is anti-dandruff hair cosmetic composition, characterized in that 0.01 to 2.0% by weight based on the total weight of the composition. The method of claim 1, The content of the trihydroxystearin is anti-dandruff hair cosmetic composition, characterized in that 0.01 to 5% by weight based on the total weight of the composition. The method of claim 1, The composition is an anti-dandruff hair cosmetic composition, characterized in that the pH is 4.0 to 6.0. The method of claim 4, wherein The hair cosmetic composition is an anti-dandruff hair cosmetic composition, characterized in that it has a formulation selected from the group consisting of shampoo, rinse, hair tonic and hair treatment. The method of claim 5, The formulation is an anti-dandruff hair cosmetic composition, characterized in that the shampoo.

Images