KR20090095359A - Hair compositions comprising an extract of griffonia simplicifolia and an extract of charnaecyparis obtusa - Google Patents

Abstract

A composition for hair containing Griffonia simplicifolia extract and Chamaecyparis obtuse extract is provided to ensure effect of preventing dandruff and removing scalp itching. A cosmetic composition for hair comprises Griffonia simplicifolia extract and Chamaecyparis obtuse extract as active ingredient. The Griffonia simplicifolia extract is obtained by extracting seeds of Griffonia simplicifolia extract with 50-99% ethanol solution. The Chamaecyparis obtuse extract is isolated using leave and branches with ether.

Description

Hair composition comprising griffon extract and cypress extract as active ingredients {HAIR COMPOSITIONS COMPRISING AN EXTRACT OF GRIFFONIA SIMPLICIFOLIA AND AN EXTRACT OF CHARNAECYPARIS OBTUSA}

The present invention relates to a composition for hair comprising dandruff and itching is prevented, and derived from a natural substance having excellent deodorizing effect and safe to humans as an active ingredient.

Dermatitis is an inflammation of the skin and is usually used in the same sense as eczema. It is classified into atopic dermatitis, contact dermatitis and seborrhoeic dermatitis. The atopic dermatitis is an eczema-like skin lesion that occurs in atopic dermatitis, also called endogenous eczema. The contact dermatitis refers to inflammation of the skin caused by contact with an external substance, characterized by the so-called skin itching. In addition, the seborrheic dermatitis refers to dermatitis, which occurs well in areas with high secretion of sebum, such as the head, forehead or armpit, and is also called seborrheic eczema. It is a dermatitis mainly caused by erythema and slenderness, or dandruff, and the lightest type is dandruff or dry tetter.

The dandruff usually refers to the lumps of keratinocytes secreted from the scalp and sebum, sweat, etc., and dead cells of the scalp naturally fall off as in normal skin, and normal dandruff is invisible. It is small so that it does not matter. When dandruff becomes a problem, abnormality arises in the general cycle of skin cells, and it develops into dry seborrhea. Dandruff, which is a mild form of seborrheic dermatitis in the scalp, is developed by the decomposition of sebaceous acid, causing fatty acid to stimulate the scalp basement cells, causing hyperplasia, accompanied by itching, and active sebaceous glands. It occurs mainly after puberty, but can occur in both men and women immediately after birth.

In relation to the cause of dandruff, Pyrosporum ovale , a scalp fungus, promotes rancidity of sebum, or Malassezia sp. It has been reported to be caused by overproliferation due to environmental factors such as stress, climate change, sweat, food, etc., and when the yeast bacteria of the genus Malassezia overproliferate, symptoms of dandruff such as scale and itching appear, and excessive Seborrheic dermatitis has been reported to develop in severe cases (Bergbrant IM Seborrhoeic dermatitis and Pityrosporum yeasts. Current Topics in Medical Mycology. 6: 95-112, 1995). In addition, if a lot of dandruff occurs due to itching, such as excessive scrubbing of the scalp, resulting in wounds, or in some cases may cause inflammation, may cause hair loss.

Conventionally commercially available therapeutic compositions for dandruff and seborrheic dermatitis include antifungal ketoconazole, zinc pyrithion, itraconazole or pyroctone olamine. In addition, tar, sulfur, salicylic acid, and the like have been used to alleviate seborrheic dermatitis and phosphorus, and selenium sulfide has been used to suppress the hyperproliferation of epidermal cells.

However, the antifungal agents that have been used for the treatment of dandruff have a good effect on the treatment of dandruff, while most of them are artificially synthesized, which raises questions about human safety.

Particularly, zinc pyrithione is not only uniformly dispersed in the composition because it is water insoluble and has a high specific gravity, but also has a high irritation to the eye and is reported to work effectively only by adding 1% or more (Gene A. Hyde). and Mark M. Auerbach, Formulation techniques for zinc pyrithione antidandruff shampoos.Cosmetics and Toiletries, 94, 57, April, 1979; Fred H. Snyder et al , Safety evaluation of Zinc 2-Pyridiethiol 1-Oxide in Shampoo Formulation, Toxicology and Applied Pharmacology, vol. 7, p.425-437, 1965; Marks, R. The effects of a shampoo containing zinc pyrithione on the control of dandruff. Br J. Dermatol. 112. 415, 1985), zinc pyrithione causes skin dermatitis (Nielsen, NH, Allergic contact dermatitis caused by zinepyrithione associated with pustular psoriasis. Am J. Contact Dermat. 8, 170. 1997), environmental toxicity Since it may cause problems such as, there is a difficulty in applying to hair cosmetics at a high concentration.

In addition, long-term use of ketoconazole, an active ingredient of an anti-dandruff treatment such as nizoral, which is commercially available in Korea, has been a problem that may cause adverse effects on the endocrine system (Schuermeyer T, Nieschlag E. 1982. Ketoconazole induced drop in serum and saliva . testosterone Lancet 1098p;. Janssen PAJ , Symoens JE 1983. American Journal of Medicine 74: 80-85).

In addition, itraconazole, which has been studied to replace ketoconazole, is highly effective against many pathogenic fungi related to humans and has a high affinity for keratinous tissues (Van Cutsem J, Van Gerven F, Zaman R, Heeres J, Hanssen PAJ.Pharmacological and preclinical results with a new oral and topical broad spectrum antifungal R 51211.Proceedings of the 13th International Congress of Chemotherapy, Vienna, Part 40: 1-11, 1983), sweat glands with ketoconazole It is reported that it is slightly slower when taken by mouth because it is not transported through the drug, and at least 1,000 mg of prescription is required daily to prevent satisfactory treatment and recurrence (Grant SM, Clissold SP. Drugs 37 : 310-344, 1989).

In addition, pyroctonolamine or salicylic acid, which is mainly used as a bactericidal or keratin dissolving agent, is studied to make up for the defects of zinc pyrithione. Climbazole is present, but they also have low usage limits for cosmetics due to concern about irritation.

In addition, the majority of patients are prescribed several kinds of medicines at the same time, but the administration of a combination of drugs can affect the liver cells toxicity and immune system, and may cause problems that can increase the efficiency or adverse effects of a drug and (Svejgaard E. Side effects and interactions of oral antifungals. Journal of the European Academy of Dermatology and Venereology 5, page S11, 1995; Bickers DR. Journal of the american academy of Dermatology 31:. S87-S90, 1994), sometimes causing symptoms such as headache and nausea (Georgiou S, Monastirli A, Pasmatzi E, Zografakis C, Tsambaos D. Oral itraconazole therapy for pityriasis versicolor Journal of the European Academy of Dermatology and Venereology 8: 203-207, 1997).

In order to supplement the drawbacks of the dandruff and itching inhibitors, pyrotonolamine and the like are added to the hair composition, but this component has a weak sterilizing power against the causative agent of dandruff. Salicylic acid is also used, but it also has a weak sterilizing power against dandruff.

In addition, the anti-dandruff agent used in the conventional anti-dandruff hair composition has a common disadvantage that there is a problem in human safety, so the amount of the anti-dandruff agent is legally limited, so that the anti-dandruff and treatment effect is low.

Dandruff is not a serious disease that shortens human life, but because it causes psychological stress in the majority of people, methods and ingredients to prevent or treat such dandruff are continuously being studied. Harmless to the environment and humans, research on the ingredients that can cause a reduction in the number of dandruff is still incomplete.

Therefore, unlike the active ingredient or antifungal substance of the existing hair composition, there is no side effect even when ingested or used for a long time, and there is a growing demand for the development of a preventive and therapeutic composition for natural dandruff derived from natural substances that have no problems with resistance or stability. have.

Therefore, the technical problem to be achieved by the present invention, in order to solve the problems of the prior art as described above, not only is safe to the human body, there are no side effects, it has excellent dandruff prevention and treatment effect, and also with a small amount of conventional anti-dandruff components Even when used to provide a hair composition comprising a material derived from natural substances with excellent dandruff prevention and therapeutic effect.

In order to achieve the above object, the present invention provides a hair composition comprising a griffonia simplicifolia extract as an active ingredient.

In addition, the present invention in order to achieve the above object ( Chamaecyparis) obtusa ) provides a hair composition comprising the extract as an active ingredient.

In addition, the present invention provides a composition for hair comprising at least one selected from the group consisting of glyphonia extract and cypress extract as an active ingredient to achieve the above object.

Hereinafter, the present invention will be described in detail.

In order to solve the problems of the prior art as described above, the present inventors are safe to the human body when using a composition for hair containing glyphonia seed extract, which is a natural substance, while testing a substance having a dandruff prevention and therapeutic effect on various substances. It has an excellent dandruff prevention and treatment effect, and further includes a protein extract having an excellent dandruff prevention and treatment effect, or an excellent dandruff prevention and treatment effect even when a small amount of a conventional anti-dandruff ingredient is used in the extract extracted from the natural substance. And it was found that the scalp itching effect is excellent, sebum secretion suppression and deodorant effect is excellent, completed the present invention.

In the present invention, Griffonia simplicifolia is a plant mainly in West Africa and Central Africa, grows up to about 3 cm, and has mostly greenish flowers and swelling pods that can be found in most bushes. It is evergreen. The glyphonia may be one species selected from the group consisting of glyphonia seeds, flowers, leaves, stems and roots, and may preferably be seeds.

In the present invention, Chamaecyparis obtusa ) is an evergreen tree of the genus Cypressaceae, also called cypress. Mainly about 40m in height and 2m in diameter, the branches grow horizontally, the branches are drooped, the bark is reddish brown, and torn vertically. The leaves are egg-shaped ridges, thick in quality, the fruit ripens brown in September to October, the flowers bloom in April, and the male and female run on different branches by monogamy, and the male flowers are yellow. It is native to Japan, and because of its good material, it has been planted in Korea as a planting species in Jeju Island and the south coast. The protein may be one species selected from a crowd consisting of leaves, branches, seeds, flowers, stems, and roots, and preferably at least one species selected from a crowd consisting of leaves and branches.

Extraction solvent for producing an extract of the present invention may be one or more selected from the group consisting of water and organic solvents. The organic solvent may be a polar solvent such as alcohol having 1 to 5 carbon atoms such as methanol or ethanol, propylene glycol, 1,3-butylene glycol, glycerol, ethyl acetate or acetone, and a nonpolar solvent such as ether, chloroform, benzene, hexane or dichloromethane. Solvent or a mixed solvent thereof.

Specifically, in the case of griponia extract, the preferred extraction solvent may be ethanol or an ethanol aqueous solution, preferably 50-99% ethanol aqueous solution, more preferably 70-95% ethanol aqueous solution, and in the case of a cyano extract, preferred extraction solvent. May be an ether.

The extract of the present invention may be prepared according to a method for preparing an extract for a conventional plant, and specifically, may be cold extraction, hot extraction or thermal extraction, and a conventional extraction device, ultrasonic grinding extractor or fraction. Can be used.

Fractions obtained by performing the extract prepared above may be filtered or concentrated or dried to remove the solvent, it can be carried out both filtration, concentration and drying. Specifically, the filtration may be performed using a filter paper or a reduced pressure filter, the concentration may be concentrated under reduced pressure using a reduced pressure concentrator, for example, a rotary evaporator, and the drying may be performed by, for example, a lyophilization method.

In one embodiment of the present invention, the glyphonia extract is dried after removing the impurities of gryphonia seed, to prepare a dry sample, 12 hours to 96 hours, preferably 24 hours to 72 hours by adding ether to the dry sample, More preferably, the crude extract is extracted by cold immersion for 36 hours to 60 hours, and the crude extract is concentrated under reduced pressure to prepare an extract. At this time, the removal of the impurities of the gryphonia seed may be performed by washing with running water, and the dried sample may be prepared by drying the glyphonia seed from which the impurities have been removed and then pulverizing it into particles of about 50 mesh using a grinder. Can be. In addition, the obtained glyphonia extract can be stored in a deep freezer until use.

As another example, the cypress extract is dried after removing the impurities of the leaves and branches of the protein, and dried to prepare a dry sample, 12 hours to 96 hours, preferably 24 hours to 72 hours by adding ethanol to the dry sample, More preferably, the crude extract is extracted by cold dipping for 36 hours to 60 hours, and the crude extract is concentrated under reduced pressure to prepare an extract. At this time, the step of removing impurities from the leaves and branches of the cypress may be performed by washing off with running water, and the dried sample is about 50 mesh using a grinder after drying the leaves and branches of the cypress from which the impurities have been removed. It can be prepared by grinding into particles of. In addition, the obtained protein extract can be stored in a deep freezer until use.

The present invention provides a hair composition comprising at least one selected from the group consisting of the glyphonia extract and the cypress extract, preferably glyphonia extract, more preferably the glyphonia extract and the protein extract as an active ingredient. The glyphonia extract or cypress extract may be an extract obtained by the extraction solvent or a fraction obtained by additionally adding a fractional solvent to the extract. The hair composition may be for applying to hair and / or scalp, preferably hair, preferably a hair cosmetic composition, more preferably a hair cosmetic composition for preventing dandruff and / or deodorization.

The hair composition is 0.0001 to 20% by weight, preferably 0.001 to 10% by weight, more preferably 0.0001 to 20% by weight of one or more extracts selected from the group consisting of the active ingredient, that is, glyphonia extract and cypress extract, based on the total weight of the composition It may comprise 0.005 to 5% by weight. Hair composition of the present invention, when the active ingredient is included in the content range, it is possible to obtain an excellent dandruff prevention effect and deodorizing effect, excellent stability and usability of the hair cosmetic composition, foreign body to the hair or scalp after use It does not appear, there are no side effects, and can meet the economic requirements, such as the cost of manufacturing the composition, the content of the active ingredient can be appropriately adjusted according to the method of use and purpose of use of the composition for hair.

The content of the glyphonia extract and the cypress extract may be 10 to 200 parts by weight, preferably 50 to 150 parts by weight, based on 100 parts by weight of the glyphonia extract.

In the present invention, hair refers to human hair as a generic term for body hair and hair, preferably hair, and may include hair roots of hair, hair follicles, hair and scalp near hair follicles. In the present invention, the scalp refers to the skin covering the head area, usually the hair (hair) area.

In addition, the present invention in order to further improve the dandruff prevention and therapeutic effect and scalp itch removal, zinc pyrithion, pyroctone olamine, itraconazole, Climbazole, selenium sulfide (selenium sulfide), selenium disulfide (selenium disulfide), salicylic acid (salicylic acid), colloid sulfur (colloid sulfur) and ketoconazole (ketoconazole) may include one or more selected from the group consisting of additional ingredients. The content of the additional component may include 0.001 to 2% by weight, preferably 0.005 to 1% by weight, more preferably 0.01 to 0.75% by weight based on the total weight of the composition. The composition for hair of the present invention, when the additional component is included in the content range, can not cause problems such as side effects that have been a conventional problem while obtaining a more excellent dandruff prevention effect, sebum secretion effect and deodorant removal effect. However, the content of the composition may be appropriately adjusted according to the method of use and purpose of use of the hair composition. In addition to the above additional components, known anti-dandruff components may be further added within a range not impairing the object of the present invention.

In addition, according to the type or purpose of use of the external preparation according to the formulation of the hair composition may further include other ingredients in addition to the essential ingredients or additional ingredients, the additional ingredients are those having ordinary knowledge in the art to which the present invention belongs. It can select suitably and mix | blend with.

Specifically, the hair composition of the present invention, in addition to the active ingredient, materials commonly used in the preparation thereof, for example, surfactants, flavoring agents, flavoring agents, coloring agents, milking agents, pearlescent agents, higher fatty alcohols, cationic polymers, coating agents, Moisturizers such as natural moisturizing ingredients and natural vegetable oils, oil components, antioxidants, metal ion sequestrants, preservatives, bubble promoters, viscosity modifiers, pH regulators, preservatives, thickeners, proteins, polymers, buffers, solvents and the like.

The surfactant serves to remove waste matter or sebum, and may be at least one selected from anionic surfactants, amphoteric surfactants, and nonionic surfactants.

The anionic surfactants include ammonium lauryl sulfosuccinate, ammonium lauryl sulfate, ammonium acyl sarcosinate, sodium cocoyl isionate, sodium acyl glutamate, sodium methyl acyl taurate, sodium lauryl sulfate, sodium lauryl Ether sulfate, triethanolamine lauryl sulfate, dialkylsodium sulfosuccinate, polyoxyethylene lauryl ether, sodium phosphate, alpha-olefin sulfonate, and the like, and the amphoteric surfactant is betaine, for example, from 10 to 10 carbon atoms An alkyl betaine of 18, an alkyl amido propyl betaine of 10 to 18 carbon atoms, a sulfobetaine may be, for example, an alkyl sulfobetaine of 10 to 18 carbon atoms, an amide betaine type, or a steartrimonium chloride.

The nonionic surfactants include PEO sorbitan fatty acid esters such as polyoxyethylene (hereinafter referred to as PEO) sorbitan monooleate, PEO sorbitan monostearate, PEO sorbitan trioleate; Sorbitan fatty acid esters such as sorbitan monolaurate, sorbitan monopalmitate and sorbitan monotaurate; PEO glycerin fatty acid esters, such as PEO glycerin monostearate; PEO fatty acid esters, such as PEO monooleate and PEO distearate; Alkyl polyglycosides having 10 to 18 carbon atoms, ethoxylated monoglycerides, ethoxylated alcohols, ethoxylated amines, amine oxides, ethoxylated amides, cured castor oil derivatives, and the like.

The pH adjusting agent is an organic acid, such as citric acid, succinic acid, tartaric acid, lactic acid, malic acid, fumaric acid, maleic acid, glycolic acid, hydrochloric acid, sulfuric acid, phosphoric acid, nitric acid, or the like, or a combination of sodium, potassium, or ammonium salts of these acids. Triethanolamine, sodium chloride, sodium hydroxide or potassium hydroxide, and the like.

The moisturizing agent is a conventional oil used for moisturizing, for example, vegetable oil or liquid paraffin, ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, sorbitol, Collagen and the like. The moisturizing agent may be contained in an amount of 0.1 to 10 parts by weight based on the total weight of the composition, but is not limited thereto.

The oil component may be tea tree oil, pine oil, milk oil, benzyl alcohol, liquid paraffin and the like, the higher fatty alcohol may be cetyl alcohol, stearyl alcohol and the like, the cationic polymer is guarhydroxypropyl trimonium Reaction product of chloride, epoxide substituted with trimethylammonium, quaternary ammonium polymerized with hydroxyethyl cellulose (CTFA name: Polyquaternium 10), copolymer of diallyldiethylammonium chloride and acrylamide (CTFA name: poly Quaternium 7) and the like, and the coating agent may be dimethicone, dimethicone copolyol, silicone, etc., previously emulsified with a surfactant.

The preservative may be, for example, benzoic acid, paraoxybenzoic acid ester, a mixture of methylchloroisothiazolinone, phenoxyethanol, DMDM hydantoin, methyl paraben, ethyl paraben, or propyl paraben.

The solvent may be, for example, purified water, ethanol, tween 20, cyclomethicone, mineral oil or dimethicone, and the above-mentioned agents and pigments may be appropriately selected by those skilled in the art. It is possible to use ingredients used in common detergent compositions.

The pearlescent auxiliary agent may be ethylene glycol monostearate or ethylene glycol distearate, and the preservative may be methyl paraoxybenzoate, methylchloroisothiazolinone, methylisothiazolinone, or a mixture thereof, The agent and the viscosity adjusting agent may be sodium chloride, ammonium chloride or propylene glycol, the pH adjusting agent may be citric acid, phosphoric acid, sodium hydroxide or potassium hydroxide, the dye may be a water-soluble tar and the like. In addition, the hair and scalp cleansing composition may further include a hair conditioning agent such as polyquaternium-10, polyquaternium-7, methylpolysiloxane, dimethylconcopolyol or hydrolyzed animal protein.

Formulation of the composition for hair is hair shampoo, hair tonic, hair rinse, hair lotion, hair nourishing longevity, hair treatment, essence, hair pack, hair liquid, aerosol mousse, aerosol spray, aerosol mousse, aerosol spray, perm, It may be any one selected from the group consisting of bleaching agents, water dispersions, powders and oils, but may be prepared in different forms depending on the purpose of use and the type of use thereof, and is not limited to a specific type of formulation.

The composition of each formulation may contain a variety of bases and additives necessary for the formulation of the formulation and appropriate, the type and amount of these components can be easily selected by those skilled in the art within the range that can maintain the effect of the active ingredient. have.

When the hair composition is used for shampoo and the like for hair and scalp cleansing, it may further include a surfactant. The surfactant may be any one or more selected from the group consisting of, for example, synthetic anionic surfactants, amphoteric surfactants and nonionic surfactants, and the surfactants may be selectively used alone or in combination. In addition, the hair composition for hair and scalp cleansing may further include conventional ingredients for maintaining the basic properties and quality of the cleansing use, such as shampoo, and the like as a pearl foil auxiliary, preservatives, thickeners, Viscosity regulators, pH regulators, fragrances or dyes may be included.

When the formulation of the hair cosmetic composition is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, trakant, cellulose derivative, polyethylene glycol, silicone, bentonite, silita, talc or zinc oxide may be additionally added. It may include.

When the formulation of the hair cosmetic composition is a powder or a spray, it may further include lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder, and in particular, when the formulation is a spray, additionally chlorofluoro Propellants such as hydroxycarbons, propane, butane or dimethyl ether.

When the formulation of the hair cosmetic composition is a solution or emulsion, it may include a solvent, a solubilizer or an emulsifier, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, Fatty acid esters of 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan, and the like.

When the formulation of the hair cosmetic composition is a suspension, a liquid diluent such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, and microcrystals Soluble cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like may further be included.

The cosmetic composition for hair comprising at least one selected from the group consisting of glyphonia extract and cypress extract of the present invention as an active ingredient not only has an excellent prophylactic or therapeutic effect against dandruff, itching prevention effect and deodorizing effect, Unlike conventional antibiotics, it contains extracts extracted from natural glyphonia and cypress as an active ingredient, so the side effects are not a problem, so the effect is very large industrially.

Hereinafter, the present invention will be described in detail with reference to Examples. However, embodiments according to the present invention may be modified in various other forms, the scope of the present invention is not to be construed as being limited to the following embodiments, embodiments of the present invention are the technical field to which the present invention belongs To those skilled in the art is only a preferred embodiment of the present invention, the present invention is not limited by the following examples.

Preparation Example 1 Preparation of Shampoo

30% sodium lauryl sulfate, 30% polyoxyethylene lauryl sulfate, palm oil fatty acid diethanolamide, and propylene glycol were added to water in the composition ratio as shown in Table 1, and then pyrotonolamine and klimbazole according to the present invention were added to the mixture. It was added until the temperature was 70 ℃ by heating to dissolve uniformly and then cooled to 40 ℃. To this mixture was added glyphonia extract, cypress extract, zinc pyrithione, colorant, paraoxybenzoic acid ester, fragrance and citric acid, mixed and cooled to prepare a shampoo. The unit of the numerical value of Table 1 is weight%.

The glyphonia extract and the cypress extract are each ground to remove impurities of gryphonia seed or cypress leaf and eggplant, and then pulverized to about 50 mesh particles using a grinder. % Ethanol, in the case of a cypress extract, ether was added and the extraction process was performed by cold dipping for 2 days to prepare a crude extract, and then concentrated under reduced pressure to prepare an extract. The extract was stored in a quick freezer after further performing separation and filtration before being used in the composition for hair.

TABLE 1

Test Example 1

Among the adults with a lot of dandruff randomly selected 65 men and women to use the shampoo prepared in the content of Table 1 in Preparation Example 2 for one month, and then to examine the dandruff reduction effect through an interview. The evaluation was conducted by questioning whether the anti-dandruff effect was felt subjectively, and the results are shown in Table 2.

TABLE 2

Test Example 2

65 men and women were randomly selected from adults who felt itching scalp and used to prepare the shampoo prepared in Table 2 in Preparation Example 2 once every 2 days for 8 weeks, and then examined whether itching relief. Evaluation was performed subjectively by the test subjects according to the evaluation criteria of Table 3, and then averaged, and the results are shown in Table 4.

TABLE 3

TABLE 4

Test Example 3

After washing the hair, 12 males and 60 males were randomly selected from the adults with sebaceous scalp that felt uncomfortable due to the odor caused by sebum decomposition. The shampoo was used once every two days for one month, and then examined through the interview to determine whether sebum production was suppressed and deodorant effect. The evaluation was performed subjectively by the test subjects according to the evaluation criteria of Table 5, and then averaged, and the results are shown in Table 6.

TABLE 5

TABLE 6

As described in Table 2, Table 4 and Table 6, the shampoo formulations of Examples 1 to 3 containing the glyphonia extract or the cypress extract according to the present invention, the anti-dandruff, itching effect than the shampoo formulation of Comparative Example 1 Excellent sebum secretion inhibitory / deodorant effect was shown to be excellent, especially when using a combination of griponia extract and protein extract, it was confirmed that the effect is maximized.

In addition, the shampoo formulations of Examples 4 to 9 using pyroctonolamine, zinc pyrithione and klimbazole, which were found to have a conventional anti-dandruff effect, were combined with the glyphonia extract and the protein extract, and the shampoo formulations of Comparative Example 1 And compared to the shampoo formulations of Comparative Examples 2 to 4 using a combination of pyrotonolamine, zinc pyrithione, klimbazole, it can be seen that the dandruff, itching and sebum secretion inhibitory / deodorizing effect.

In addition, the hair conditioner and hair treatment in the same form as the result of the experiment was also found to be similar to the shampoo, the composition for hair containing gleephonia extract and cypress extract is excellent anti-dandruff effect and anti-itch effect, sebum secretion It was confirmed that the inhibitory and deodorant effect was excellent.

Preparation Example 3 Preparation of Hair Tonic Brothers

After mixing and dissolving l-menthol, D-panthenol, propylene glycol, pigments and flavors in the composition ratio as shown in Table 7, polyoxyethylene-cured castor oil in water and glyphonia extract according to Preparation Example 1 of the present invention An extract, pyrotonolamine, and klimbazole were added thereto, and the solution prepared by mixing and mixing was mixed to prepare a hair tonic formulation. The unit of the numerical value of Table 1 is weight%.

Tests on dandruff prevention, itching prevention and alleviation, sebum branching inhibition and deodorizing effects of the products thus prepared were carried out according to the following test examples and the results are shown in Tables 8, 10 and 12.

TABLE 7

Test Example  4

50 males were randomly selected from the adults with a lot of dandruff, and the hair tonic preparations prepared in Table 3 in Preparation Example 3 were used for one month. After trituration only with a conventional shampoo before the start of the test, using the hair tonic preparation prepared in the content of Table 7 once a day, with the amount of dandruff generated for three days and trituration once every two days with a conventional shampoo, The cumulative incidence of dandruff, which was accumulated for three days after the kind, was compared and evaluated through a questionnaire. The results of the evaluation are shown in Table 8.

TABLE 8

Test Example  5

50 men randomly selected from the adults who feel itching scalp was made to use the product prepared in the content of Table 7 in Preparation Example 3 once a day for 4 weeks, and then examined whether to reduce the itching through an interview. During this test, the shampoo was made to use the shampoo that was normally used. Evaluation was performed subjectively by the test subjects according to the evaluation criteria of Table 9, and then averaged, and the results are shown in Table 10.

TABLE 9

TABLE 10

Test Example  6

After washing the hair, 12 males and 50 females with oily scalp who feel uncomfortable due to odor caused by sebum disintegration were randomly selected from 50 males and prepared in Table 7 in Preparation Example 3. The product was used once a day for 4 weeks, and then interviewed to determine whether the sebum generation inhibition and deodorant effect. During this test, the shampoo was made to use the shampoo that was normally used. Evaluation was performed subjectively by the test subjects according to the evaluation criteria of Table 11, and then averaged, and the results are shown in Table 12.

TABLE 11

TABLE 12

As described in Table 8, Table 10, and Table 12, the hair tonic formulation of Examples 10 to 12 containing the glyphonia extract or the cypress extract according to the present invention, dandruff, itching than the hair tonic formulation of Comparative Example 5 It has been shown to be excellent in the prevention effect and sebum secretion inhibitory / deodorizing effect, especially when the glyphonia extract and the protein extract is used together, the effect was maximized.

In addition, the hair tonic formulations of Examples 13 to 16, which used pyrotonolamine, zinc pyrithione, and klimbazole, which were found to have an existing anti-dandruff effect, were mixed with the glyphonia extract and the protein extract, the hair tonic of Comparative Example 5 It can be seen that compared to the shampoo formulations of Comparative Examples 6 and 7 using a sibling agent and the pyrotonolamine and klimbazole, it has dandruff, itching reduction and sebum secretion suppressing / deodorizing effect.

In addition, the hair mousse, hair spray and hair cream produced in the same manner as the experimental results also come out similar to the hair tonic, glyphonia extract and the composition for hair including the extract is excellent anti-dandruff effect and itching prevention effect It was confirmed that the sebum secretion suppression and deodorizing effect was excellent.

Claims (7)

Griffonia simplicifolia ) Hair cosmetic composition comprising at least one selected from the group consisting of Chamaecyparis obtusa extract as an active ingredient. The method of claim 1, The glyphonia extract is a hair cosmetic composition prepared by adding 50 to 99% ethanol aqueous solution to gryphonia seed. The method of claim 1, The cypress extract is a hair cosmetic composition prepared by adding ether ether for at least one selected from the group consisting of cypress leaves and branches. The method of claim 1, The content of the gryphonia extract and the cypress extract is 10 to 200 parts by weight of the hair extract according to 100 parts by weight of the glyphonia extract. The method of claim 1, The amount of the active ingredient is 0.0001 to 20% by weight based on the total weight of the composition cosmetic composition for hair. The method according to any one of claims 1 to 5, The hair cosmetic composition is zinc pyrithion, pyroctone olamine, itraconazole, crimazole, selenium sulfide, selenium disulfide, salicylic acid acid), colloidal sulfur (colloid sulfur) and ketoconazole (ketoconazole) at least one selected from the group consisting of a hair composition, characterized in that it further comprises 0.001 to 2% by weight based on the total weight, respectively. The method of claim 6, The formulation of the cosmetic composition for hair is hair shampoo, hair tonic, hair rinse, hair lotion, hair nourishing longevity, hair treatment, essence, hair pack, hair liquid, aerosol mousse, non aerosol spray, aerosol mousse, aerosol spray, perm Cosmetic composition for hair, any one selected from the group consisting of a bleach, a water dispersion, a powder and an oil.