KR20100043201A - 성장 호르몬 융합 단백질 - Google Patents
성장 호르몬 융합 단백질 Download PDFInfo
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- KR20100043201A KR20100043201A KR1020107002192A KR20107002192A KR20100043201A KR 20100043201 A KR20100043201 A KR 20100043201A KR 1020107002192 A KR1020107002192 A KR 1020107002192A KR 20107002192 A KR20107002192 A KR 20107002192A KR 20100043201 A KR20100043201 A KR 20100043201A
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C07K—PEPTIDES
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- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US95112207P | 2007-07-20 | 2007-07-20 | |
| US60/951,122 | 2007-07-20 | ||
| GBGB0717985.6A GB0717985D0 (en) | 2007-07-20 | 2007-09-14 | Growth hormone fusion proteins |
| GB0717985.6 | 2007-09-14 |
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| KR20100043201A true KR20100043201A (ko) | 2010-04-28 |
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| JP (1) | JP5546452B2 (enExample) |
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| CA (1) | CA2693951A1 (enExample) |
| GB (1) | GB0717985D0 (enExample) |
| IL (1) | IL202225A (enExample) |
| RU (1) | RU2473554C2 (enExample) |
| WO (1) | WO2009013461A1 (enExample) |
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| GB0606946D0 (en) * | 2006-04-06 | 2006-05-17 | Asterion Ltd | Polypeptide antagonist |
| GB0717985D0 (en) * | 2007-07-20 | 2007-10-24 | Asterion Ltd | Growth hormone fusion proteins |
| GB0719818D0 (en) * | 2007-10-11 | 2007-11-21 | Asterion Ltd | Growth hormone fusion polypeptides |
| GB201104285D0 (en) * | 2011-03-15 | 2011-04-27 | Asterion Ltd | Modified receptor fusion proteins |
| US10039813B2 (en) | 2012-02-07 | 2018-08-07 | Massachusetts Institute Of Technology | Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness |
| US9724396B2 (en) | 2013-03-15 | 2017-08-08 | Massachusetts Institute Of Technology | Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness |
| GB201316592D0 (en) * | 2013-09-18 | 2013-10-30 | Levicept Ltd | Fusion protein |
| WO2016138099A1 (en) | 2015-02-24 | 2016-09-01 | Massachusetts Institute Of Technology | Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness |
| GB201520021D0 (en) | 2015-11-13 | 2015-12-30 | Asterion Ltd | Fusion polypeptide |
| GB201706781D0 (en) | 2017-04-28 | 2017-06-14 | Univ Sheffield | Parathyroid hormone fusion polypeptide |
| EP3930687A4 (en) | 2019-02-25 | 2023-06-07 | The University of Chicago | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS USING ECM AFFINITY PEPTIDES LINKED TO ANTI-INFLAMMATORY AGENTS |
| CN113880954B (zh) * | 2021-09-29 | 2024-05-14 | 江苏大学 | 一种重组人生长激素及其构建方法和应用 |
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| EP1290170A2 (en) * | 2000-06-16 | 2003-03-12 | Asterion Limited | Binding agents: chimeric ligand/receptor proteins |
| GB2389115B (en) * | 2001-12-14 | 2005-03-16 | Asterion Ltd | Polypeptide having a plurality of modified growth hormone receptor binding domains of growth hormone |
| US7625998B2 (en) * | 2003-04-09 | 2009-12-01 | Asterion Limited | Cytokine polypeptides and antibodies containing a signal sequence for the attachment of glycosylphosphatidylinositol |
| US20090221477A1 (en) | 2004-07-26 | 2009-09-03 | Asterion Limited | Linkers |
| GB0606946D0 (en) * | 2006-04-06 | 2006-05-17 | Asterion Ltd | Polypeptide antagonist |
| GB0717985D0 (en) * | 2007-07-20 | 2007-10-24 | Asterion Ltd | Growth hormone fusion proteins |
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2007
- 2007-09-14 GB GBGB0717985.6A patent/GB0717985D0/en not_active Ceased
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2008
- 2008-07-16 WO PCT/GB2008/002406 patent/WO2009013461A1/en not_active Ceased
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- 2008-07-16 US US12/669,451 patent/US8293709B2/en not_active Expired - Fee Related
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- 2008-07-16 EP EP08775945A patent/EP2170943A1/en not_active Withdrawn
- 2008-07-16 CN CN2008800214732A patent/CN101679504B/zh not_active Expired - Fee Related
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2012
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Also Published As
| Publication number | Publication date |
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| CA2693951A1 (en) | 2009-01-29 |
| CN101679504B (zh) | 2013-06-19 |
| EP2170943A1 (en) | 2010-04-07 |
| AU2008278907B2 (en) | 2012-08-23 |
| US8293709B2 (en) | 2012-10-23 |
| WO2009013461A1 (en) | 2009-01-29 |
| IL202225A (en) | 2013-12-31 |
| AU2008278907A1 (en) | 2009-01-29 |
| RU2010103157A (ru) | 2011-08-27 |
| US8470559B2 (en) | 2013-06-25 |
| US20130023477A1 (en) | 2013-01-24 |
| US20100197582A1 (en) | 2010-08-05 |
| CN101679504A (zh) | 2010-03-24 |
| JP2010534060A (ja) | 2010-11-04 |
| WO2009013461A8 (en) | 2010-01-07 |
| RU2473554C2 (ru) | 2013-01-27 |
| IL202225A0 (en) | 2010-06-16 |
| JP5546452B2 (ja) | 2014-07-09 |
| GB0717985D0 (en) | 2007-10-24 |
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