KR20090125100A - 경점막 전달을 증진시키기 위한 조성물 및 방법 - Google Patents

경점막 전달을 증진시키기 위한 조성물 및 방법 Download PDF

Info

Publication number
KR20090125100A
KR20090125100A KR1020097019200A KR20097019200A KR20090125100A KR 20090125100 A KR20090125100 A KR 20090125100A KR 1020097019200 A KR1020097019200 A KR 1020097019200A KR 20097019200 A KR20097019200 A KR 20097019200A KR 20090125100 A KR20090125100 A KR 20090125100A
Authority
KR
South Korea
Prior art keywords
composition
oil
phenylalanine
methylsulfonylmethane
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020097019200A
Other languages
English (en)
Korean (ko)
Inventor
요셉 루빈스타인
Original Assignee
데마-영 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데마-영 리미티드 filed Critical 데마-영 리미티드
Publication of KR20090125100A publication Critical patent/KR20090125100A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020097019200A 2007-02-15 2008-02-14 경점막 전달을 증진시키기 위한 조성물 및 방법 Ceased KR20090125100A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90134507P 2007-02-15 2007-02-15
US60/901,345 2007-02-15

Publications (1)

Publication Number Publication Date
KR20090125100A true KR20090125100A (ko) 2009-12-03

Family

ID=39690605

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097019200A Ceased KR20090125100A (ko) 2007-02-15 2008-02-14 경점막 전달을 증진시키기 위한 조성물 및 방법

Country Status (10)

Country Link
US (1) US20100086495A1 (https=)
EP (1) EP2114384A4 (https=)
JP (1) JP2010519196A (https=)
KR (1) KR20090125100A (https=)
CN (1) CN101754755A (https=)
AU (1) AU2008215771A1 (https=)
BR (1) BRPI0807943A2 (https=)
CA (1) CA2678500A1 (https=)
WO (1) WO2008099397A2 (https=)
ZA (1) ZA200905697B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101484481B1 (ko) * 2014-08-07 2015-01-20 주식회사 다림바이오텍 Pde-5 저해제를 포함하는 설하분무제의 제조방법 및 이에 의하여 제조된 설하분무용 조성물

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2010019276A2 (en) * 2008-08-15 2010-02-18 Chakshu Research, Inc. Method and formulation for treating adverse biological conditions
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yed�Tepe �N�Vers�Tes� Doğal bileşenler içeren bir film şeridi.
KR101171832B1 (ko) 2009-10-30 2012-08-14 박경식 부작용을 제거한 장기간 복용 차 및 그 조성물
TR201103770A1 (tr) * 2011-04-19 2012-11-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Nimesulid ve metilsülfonilmetanin topikalfarmasötik bileşimleri.
DK2844344T3 (da) * 2012-05-03 2021-04-19 Rajiv Bhushan Behandling af inflammatoriske tilstande og forbedring af mundhygiejne ved hjælp af metalmodulatorer med methylsulfonylmethan som transportforbedrer
WO2014024193A1 (en) * 2012-08-07 2014-02-13 Prodel Pharma Ltd. Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
EP2941128B1 (en) 2012-12-20 2023-06-28 Rajiv Bhushan Antimicrobial compositions
FR3000896B1 (fr) * 2013-01-14 2016-08-26 Philippe Perovitch Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil
US20160095868A1 (en) * 2013-04-17 2016-04-07 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
CN104352461B (zh) * 2013-04-28 2017-07-14 南京海融医药科技股份有限公司 他达拉非的口服药物制剂
US9855234B2 (en) 2014-07-08 2018-01-02 Insys Development Company, Inc. Diclofenac sublingual spray
NL2015957B1 (en) * 2015-12-14 2017-06-29 Scala Pharma B V Compositions and methods for inducing beige or brown fat tissue.
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
CN111956652A (zh) * 2020-08-21 2020-11-20 重庆康刻尔制药股份有限公司 一种西地那非口腔膜剂药物组合及其制备方法
WO2022115953A1 (en) * 2020-12-04 2022-06-09 Inovobiologic, Inc. Eutectic matrix for nutraceutical compositions
US20240382597A1 (en) * 2021-12-31 2024-11-21 LIVIONEX, Inc. Formulations of anti-inflammatory agents comprising msm with enhanced solubility in water

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568547A (en) * 1979-08-30 1986-02-04 Herschler R J Solid pharmaceutical compositions comprising MSM and their production
US4973605A (en) * 1979-08-30 1990-11-27 Herschler R J Use of methylsulfonylmethane to relieve pain and relieve pain and nocturnal cramps and to reduce stress-induced deaths in animals
US4559329A (en) * 1982-09-14 1985-12-17 Herschler R J Dietary and pharmaceutical uses of methyl-sulfonylmethane and compositions comprising it
US4447469A (en) * 1982-06-10 1984-05-08 Hughes Aircraft Company Process for forming sulfide layers by photochemical vapor deposition
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4883128A (en) * 1986-07-30 1989-11-28 Donald L. O'Neall Guidance system for farm implements
WO1994005293A1 (en) * 1992-09-04 1994-03-17 Aws Shakir Mustafa Salim Skin treatment compositions containing dimethylsulphone and allopurinol or oxypurinol
US5346701A (en) * 1993-02-22 1994-09-13 Theratech, Inc. Transmucosal delivery of macromolecular drugs
US6197356B1 (en) * 1993-08-03 2001-03-06 Immunopath Profile, Inc. Process for preparing hypoallergenic foods
US5670163A (en) * 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
US5569679A (en) * 1994-12-30 1996-10-29 Russell A. Krueger Pharmaceuticals, Inc. Pharmacologic management of snoring
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US5925377A (en) * 1997-08-07 1999-07-20 Nova Pharmaceutical Co. Dietary supplement composition
US6203820B1 (en) * 1998-05-28 2001-03-20 Brice E. Vickery Compositions and methods for enhancing protein anabolism and detoxification
ATE399565T1 (de) * 1998-07-07 2008-07-15 Transdermal Technologies Inc Zusammensetzungen für die schnelle und nicht- irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung
SE9803986D0 (sv) * 1998-11-23 1998-11-23 Pharmacia & Upjohn Ab New compositions
US6440391B1 (en) * 2000-06-02 2002-08-27 Elstan Corporation Management of snoring by oral administration of dimethyl sulfone
US6416772B1 (en) * 2001-01-12 2002-07-09 H. Wayne Van Engelen Topical dermal anaesthetic
US6541045B1 (en) * 2002-01-04 2003-04-01 Nutraceutical Corporation Herbal composition and method for combating inflammation
US7186692B2 (en) * 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
US20060177430A1 (en) * 2002-12-20 2006-08-10 Chakshu Research Inc Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer
NZ540885A (en) * 2002-12-20 2009-02-28 Chakshu Res Inc Ophthalmic formulation for the prevention and treatment of ocular conditions
US20040151771A1 (en) * 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
US20050181047A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements
MXPA06012059A (es) * 2004-04-22 2007-01-25 Boehringer Ingelheim Int Nuevas composiciones farmaceuticas para el tratamiento de los trastornos sexuales ii.
US20050244502A1 (en) * 2004-04-28 2005-11-03 Mathias Neil R Composition for enhancing absorption of a drug and method
JP2006290792A (ja) * 2005-04-11 2006-10-26 Tm East:Kk 抗炎症剤

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101484481B1 (ko) * 2014-08-07 2015-01-20 주식회사 다림바이오텍 Pde-5 저해제를 포함하는 설하분무제의 제조방법 및 이에 의하여 제조된 설하분무용 조성물

Also Published As

Publication number Publication date
WO2008099397A3 (en) 2010-01-07
ZA200905697B (en) 2010-10-27
AU2008215771A1 (en) 2008-08-21
JP2010519196A (ja) 2010-06-03
EP2114384A4 (en) 2012-02-01
US20100086495A1 (en) 2010-04-08
CN101754755A (zh) 2010-06-23
BRPI0807943A2 (pt) 2014-10-21
EP2114384A2 (en) 2009-11-11
WO2008099397A2 (en) 2008-08-21
CA2678500A1 (en) 2008-08-21

Similar Documents

Publication Publication Date Title
KR20090125100A (ko) 경점막 전달을 증진시키기 위한 조성물 및 방법
JP6158801B2 (ja) 代謝経路を変調させるための組成物および方法
CN104918610B (zh) 用于增强能量代谢的组合物和方法
US20130189361A1 (en) Combination tablet with chewable outer layer
WO2014024193A1 (en) Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
US20190388377A1 (en) Compositions and methods for the treatment of liver diseases and disorders
WO2008122190A1 (en) The composition comprising l-carnitine or derivatives thereof and its use
JP5542309B2 (ja) 経口医薬組成物
WO2008134540A1 (en) Compositions and methods for transmucosal delivery of domperidone
JP2016056195A (ja) ロキソプロフェン含有経口用組成物5
TW200534852A (en) 4-methylpyrazole formulations for inhibiting ethanol intolerance
US20220008342A1 (en) Combination tablet with chewable outer layer
RU2307651C2 (ru) Каппа-опиатные агонисты для лечения заболеваний мочевого пузыря
CN108703946A (zh) 一种治疗糖尿病周围神经痛的透皮吸收制剂
BR112019014942A2 (pt) terapia de combinação para tratamento de doenças da pele
US12246042B2 (en) Methods for alleviating, inhibiting or reversing muscle disuse atrophy in mammals
TR2022020426A2 (tr) İndometazi̇n ve famoti̇di̇n?i̇ bi̇r arada i̇çeren ağizda dağilan tablet (odt) formülasyonlari
CN120225185A (zh) 5-甲氧基-2-氨基茚满(“meai”)在用于治疗代谢综合征的方法中的用途
HK1145630A (en) Compositions and methods for enhancing transmucosal delivery
JP2014070024A (ja) フェニルプロピオン酸系消炎鎮痛薬を含有する医薬組成物
KR101572311B1 (ko) 2-아미노-2-노보네인카르복실산을 함유하는 비만 예방 또는 치료용 조성물
WO2025148866A1 (en) Use of dihydroberberine or its derivatives for regulating glp-1
JP2021054722A (ja) ロキソプロフェン又はその塩とボウイとを含有する経口医薬組成物
WO2024144678A1 (en) Orally disintegrating tablets (odt) formulations for the treatment of flu, common cold and allergic symptoms
TR2023019244A1 (tr) Montelukast ve desloratadi̇n?i̇ bi̇r arada i̇çeren oral i̇nce fi̇lm formülasyonlari

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20090914

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20130214

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20140206

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20140801

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20140206

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I