JP2010519196A - 経粘膜送達を高めるための組成物および方法 - Google Patents

経粘膜送達を高めるための組成物および方法 Download PDF

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JP2010519196A
JP2010519196A JP2009549493A JP2009549493A JP2010519196A JP 2010519196 A JP2010519196 A JP 2010519196A JP 2009549493 A JP2009549493 A JP 2009549493A JP 2009549493 A JP2009549493 A JP 2009549493A JP 2010519196 A JP2010519196 A JP 2010519196A
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amount
present
composition
oil
phenylalanine
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JP2010519196A5 (https=
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ヨセフ ルビンシュタイン
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ダーマ−ヤング リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2009549493A 2007-02-15 2008-02-14 経粘膜送達を高めるための組成物および方法 Pending JP2010519196A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90134507P 2007-02-15 2007-02-15
PCT/IL2008/000192 WO2008099397A2 (en) 2007-02-15 2008-02-14 Compositions and methods for enhancing transmucosal delivery

Publications (2)

Publication Number Publication Date
JP2010519196A true JP2010519196A (ja) 2010-06-03
JP2010519196A5 JP2010519196A5 (https=) 2011-03-31

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ID=39690605

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JP2009549493A Pending JP2010519196A (ja) 2007-02-15 2008-02-14 経粘膜送達を高めるための組成物および方法

Country Status (10)

Country Link
US (1) US20100086495A1 (https=)
EP (1) EP2114384A4 (https=)
JP (1) JP2010519196A (https=)
KR (1) KR20090125100A (https=)
CN (1) CN101754755A (https=)
AU (1) AU2008215771A1 (https=)
BR (1) BRPI0807943A2 (https=)
CA (1) CA2678500A1 (https=)
WO (1) WO2008099397A2 (https=)
ZA (1) ZA200905697B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015515991A (ja) * 2012-05-03 2015-06-04 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2016504405A (ja) * 2013-01-14 2016-02-12 ロッセロ ラファエル ガレヌス製剤の有効成分の投与剤形

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US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2010019276A2 (en) * 2008-08-15 2010-02-18 Chakshu Research, Inc. Method and formulation for treating adverse biological conditions
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yed�Tepe �N�Vers�Tes� Doğal bileşenler içeren bir film şeridi.
KR101171832B1 (ko) 2009-10-30 2012-08-14 박경식 부작용을 제거한 장기간 복용 차 및 그 조성물
TR201103770A1 (tr) * 2011-04-19 2012-11-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Nimesulid ve metilsülfonilmetanin topikalfarmasötik bileşimleri.
WO2014024193A1 (en) * 2012-08-07 2014-02-13 Prodel Pharma Ltd. Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
EP2941128B1 (en) 2012-12-20 2023-06-28 Rajiv Bhushan Antimicrobial compositions
US20160095868A1 (en) * 2013-04-17 2016-04-07 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
CN104352461B (zh) * 2013-04-28 2017-07-14 南京海融医药科技股份有限公司 他达拉非的口服药物制剂
US9855234B2 (en) 2014-07-08 2018-01-02 Insys Development Company, Inc. Diclofenac sublingual spray
KR101484481B1 (ko) * 2014-08-07 2015-01-20 주식회사 다림바이오텍 Pde-5 저해제를 포함하는 설하분무제의 제조방법 및 이에 의하여 제조된 설하분무용 조성물
NL2015957B1 (en) * 2015-12-14 2017-06-29 Scala Pharma B V Compositions and methods for inducing beige or brown fat tissue.
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
CN111956652A (zh) * 2020-08-21 2020-11-20 重庆康刻尔制药股份有限公司 一种西地那非口腔膜剂药物组合及其制备方法
WO2022115953A1 (en) * 2020-12-04 2022-06-09 Inovobiologic, Inc. Eutectic matrix for nutraceutical compositions
US20240382597A1 (en) * 2021-12-31 2024-11-21 LIVIONEX, Inc. Formulations of anti-inflammatory agents comprising msm with enhanced solubility in water

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JPH10503482A (ja) * 1994-06-20 1998-03-31 ケーヴィ・ファーマスーティカル・カンパニー 改良された長時間作用型胃腸・食道保護剤
WO1999061042A1 (en) * 1998-05-28 1999-12-02 Vickery Brice E Compositions and methods for enhancing protein anabolism and detoxification
JP2006514696A (ja) * 2002-12-20 2006-05-11 チャクシュ・リサーチ・インコーポレーテッド 眼球の症状の予防及び治療のための眼科用製剤
JP2006290792A (ja) * 2005-04-11 2006-10-26 Tm East:Kk 抗炎症剤

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JPH10503482A (ja) * 1994-06-20 1998-03-31 ケーヴィ・ファーマスーティカル・カンパニー 改良された長時間作用型胃腸・食道保護剤
WO1999061042A1 (en) * 1998-05-28 1999-12-02 Vickery Brice E Compositions and methods for enhancing protein anabolism and detoxification
JP2006514696A (ja) * 2002-12-20 2006-05-11 チャクシュ・リサーチ・インコーポレーテッド 眼球の症状の予防及び治療のための眼科用製剤
JP2006290792A (ja) * 2005-04-11 2006-10-26 Tm East:Kk 抗炎症剤

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015515991A (ja) * 2012-05-03 2015-06-04 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2019206572A (ja) * 2012-05-03 2019-12-05 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2016504405A (ja) * 2013-01-14 2016-02-12 ロッセロ ラファエル ガレヌス製剤の有効成分の投与剤形

Also Published As

Publication number Publication date
WO2008099397A3 (en) 2010-01-07
ZA200905697B (en) 2010-10-27
AU2008215771A1 (en) 2008-08-21
EP2114384A4 (en) 2012-02-01
US20100086495A1 (en) 2010-04-08
CN101754755A (zh) 2010-06-23
BRPI0807943A2 (pt) 2014-10-21
EP2114384A2 (en) 2009-11-11
KR20090125100A (ko) 2009-12-03
WO2008099397A2 (en) 2008-08-21
CA2678500A1 (en) 2008-08-21

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