KR20090085845A - Shampoo compositions - Google Patents

Abstract

A shampoo composition is provided to interfere the proliferation and activation of fungus and Malassezia furfur Bailon (especially Pityrosporum Ovlae). A shampoo composition comprises a mastic. The mastic is emulsified with oil. The mastic is contained in a ration of 0.1-10 weight% based on the total composition. The oil component is an organic oil, benzyl alcohol, liquid parapine such as cocamide DEA, aromatic oil, perfume, tea tree oil, pine oil, and milk oil. The composition further comprises surfactant, cationic polymer, coating agent, mastic, and anti-dandruff agent.

Description

Shampoo Compositions

The present invention relates to a shampoo composition that can prevent the itching and inflammation by inhibiting the growth and activity of fungi and dandruff causing the scalp itch and scalp keratin (dandruff) and inflammation.

In general, the scalp is replaced with a new scalp at a faster rate than the hair, which is replaced with new cells about once a month.

In a healthy scalp, the stratum corneum cells fall off to an invisible size and quickly replace with new keratinocytes.

However, too many keratinocytes are produced and clumps of keratinocytes are visible and peeled off the scalp. This is called dandruff.

Dandruff disease causes dead cells of the scalp to come off as a hard keratin form, united with sebum and sweat secreted from the scalp, and agglomerates into large masses. It is known as a symptom accompanied by itching or appearing as a microorganism or the like grows on its own or outside.

Since the first theory in Dandelion was raised in France in 1874 that dandruff was the cause of dandruff, it was not until 100 years later that 1984 finally succeeded in identifying the identity of dandruff. The stagnation of dandruff is Pytirosporum ovale, and it has been confirmed that dandruff occurs when the bacteria increase by more than 10-20 times the normal number.

And dandruff is usually accompanied by itching of the scalp at this time, if you scratch the scalp hard to hurt and eventually cause inflammation, eczema, hair loss occurs. (Dermatology, Korean Dermatology Publishing Committee, Yeomungak, 1992).

The anti-dandruffs reported so far include zinc pyrithione, selenium sulfide, pyroctone olamine, cimbazole, salicylic acid, ketoconazole , CoalTar, Corticosteroid, Colloid Sulfur, Selenium disulfide and many other natural products.

The US FDA states that sulfur is effective for dandruff, selenium sulfide and zinc pyrithione are effective for seborrheic Dermatitis, and other salicylic acids and kohl tar are recognized as anti-dandruff agents.

However, most of these anti-dandruff agents are characterized by strong bactericidal power, and most of them have side effects or toxicity, so it is difficult to use more than a certain amount. Zinc pyrithione is 0.5% or less, even in the raw materials described in the Korean Pharmaceutical Affairs Law Ordinance. The content is regulated to less than 0.5% (refer to the 1998 edition of the Code of Pharmaceutical Affairs Law, treatment guidelines such as cosmetics manufacturing and manufacturing product license).

The above anti-dandruff components must be kept on the cleaned surface in order to have an anti-dandruff effect, and the amount of adsorption on the hair and the scalp will increase if more contents are incorporated into the composition. However, in this case, side effects and toxicity that bactericidal antibacterial agents have in common are problematic.

However, even though treatment of the scalp with antimicrobial agents reduced the microbes on the scalp, it has been reported that dandruff is not completely reduced. In addition, although the hot and humid summer is the optimal condition for the growth of dandruff microorganisms, dandruff is much more present in winter than in summer. In summary, the occurrence of dandruff by Pityrosporum Ovlae is only part of dandruff development. It was also argued that this was a result, not a cause.

Despite the ongoing research on dandruff, the underlying cause of the development is still unclear, but in general, neurological factors such as endocrine hormone imbalance, metabolic imbalance, stress, and excessive growth of scalp cells Biochemical changes in epithelial tissue, increased growth and activity of scalp microorganisms, and inflammation caused by air pollution have been described as being caused by a combination of factors.

Therefore, hair cosmetics aimed at the treatment and prevention of dandruff and scalp itch effectively inhibit the proliferation and activity of yeast and phytirosporum obale, which are the main causes of dandruff, and normalize abnormal metabolic activity of scalp cells. It is desired to contain a component that can be used.

Accordingly, the present inventors, while reviewing a substance having a bactericidal and antimicrobial effect against pytirosporm obale, a major causative agent of dandruff, without hypoallergenic and safety problems in humans, 2001 Safety was confirmed through a special research project in the Ministry of Health and Welfare of the year. The present invention has been completed by focusing on the fact that mastic, which does not apply to good bacteria but selectively acts on bad bacteria and shows excellent inhibitory effect, can reduce or control dandruff. Accordingly, an object of the present invention is to use a natural material derived from a natural source in combination with conventional hair cosmetics, familiar to the consumer and not objectionable, hypoallergenic and safety of the human body, without the problem of excellent bactericidal effect, especially dandruff The present invention provides a shampoo composition exhibiting an effect of inhibiting proliferation and activity and a deodorizing effect.

In order to achieve the above object, the shampoo composition according to the present invention contains mastic erupted from the stem of Pistacia Lentiscus L. species, an evergreen shrub with Anacardiaceae. To provide a shampoo composition.

The mastic has long been produced on the Greek island of Chios, and indigenous people have long used mastic in the form of folk remedies.

The components of the mastic are α-pinene, camphor, β-pinene, savinen, myrsen, δ-3-karenne, limonene, eucalyptol, Yy-terpinene, p-cymene, terpinolene, terpinene-1- Ol-4 and α-terpineol. Fragrance Raw Materials Monographs, Mastic Absolute [“Triterpenoids From Gum Mastic, The Resin of Pistacia Lentiscus”, Phytochemistry, Vol. 30, No. 11, pp. 3709-3712, 1991.

As described above, the composition of the shampoo containing mastic inhibits the growth and activity of fungi and dandruff bacteria present in the scalp, which greatly helps to reduce dandruff and itching, and also improves the scalp to reduce hair loss. Also appeared to contribute. It is expected to help relieve the irritation associated with fungus and stress and natural requirements, helping to keep your hair clean, healthy, beautiful and rich.

Shampoo compositions according to the invention contain surfactants conventional in the art. Such surfactants include anionic surfactants, amphoteric surfactants, nonionic surfactants, and the like. Representative anionic surfactants that can be used in the present shampoo composition are sodium acyl glutamate, ammonium acyl sarcosinate, sodium methyl acyl taurate, sodium acyl isethionate, dialkyl sodium sulfosuccinate, polyoxyethylene lauryl ether Sodium phosphate, (alpha)-olefin sulfonate, the compound represented by following formula (1), or 2 or more types of these mixtures are mentioned. The content of the preferred surfactant in the shampoo composition of the present invention is 2 to 40% by weight.

Preferred examples of the anionic surfactants include sodium laureth (3) sulfite, decylglucoside, sodium lauryl sulfate, sodium lauryl ether sulfate, potassium lauryl ether sulfate, ammonium lauryl sulfate, ammonium lauryl ether sulfate and lauryl sulfate monoethanol Amine, lauryl diethanolamine, lauryl triethanolamine, sodium polyoxyethylene lauryl sulfate, etc. are mentioned.

In addition, it is possible to contain amphoteric surfactants and nonionic surfactants in order to improve the foaming and foaming feeling of the shampoo composition of the present invention and improve the mildness (mildness) of the composition.

Suitable amphoteric surfactants for inclusion in the composition include C10-C18 alkylbetaines, C10-C18 alkylamidopropylbetaines, C10-C18 alkylsulfobetaines, or mixtures of two or more thereof. Representative examples thereof include cocamidopropyl betaine, lauryl dimethylamino acetic acid betaine, cocamidopropyl hydroxy sulfane and the like. The content of the amphoteric surfactant is preferably 0.5 to 10% by weight based on the total weight of the composition.

In addition, the present invention provides a cationic polymer selected from the group consisting of cationic derivatives of guar rubber, water-soluble nitrogen-containing polymers, and mixtures thereof in order to provide conditioning benefits to the composition and at the same time have antistatic properties after use of shampoo. 5.0 weight%. Representative examples of such cationic polymers include guarhydroxypropyl trimorium chloride, reaction products of epoxides substituted with trimethylammonium and quaternary ammonium polymerized with hydroxyethyl cellulose (CTFA name: Polyquiternium 10), diallyl Copolymers of diethylammonium chloride and acrylamide (CTFA name: Polyquiternium 7).

In order to improve the hair glossiness and the feeling of combing, a silicone emulsion previously emulsified with DL-panthenol, dimethicone, dimethicone copolyol, and a surfactant may be used as a coating agent, or may be used in combination with an amino modified silicone. The content of the coating agent is 0.1 to 10.0% by weight, preferably 0.5 to 5.0% by weight based on the total composition.

When using less than 0.1% by weight it is difficult to expect a substantial conditioning effect, when using more than 10.0% by weight can cause build-up phenomenon to the hair due to excessive content.

The mastic of the present invention can be mixed or extracted in a suitable solvent of water, alcohol, oil, and is preferably mastic oil emulsified in the oil contained in the shampoo composition.

In other words, the conventional shampoo composition contains a large amount of surfactant for the cleaning power and foamability which is an inherent function of the shampoo, in this case, since the mastic component, which is an antimicrobial agent, can be easily washed off by the surfactant.

The composition of the present invention is an oil component for dissolving mastic, organic oils such as cocamide DEA, aroma oil, perfume, tea tree oil, pine oil, milk oil, and benzyl alcohol, liquid paraffin, etc. which are usually contained in shampoo compositions. Can be mentioned.

The content of this oil component is 0.1 to 10.0% by weight, preferably 0.5 to 5.0% by weight based on the total composition.

In addition to the above oil components, in order to obtain an emulsion suitable for the present invention, components having insoluble properties in surfactants while dissolving mastic may be used alone or in combination.

The present invention makes it possible to obtain a synergistic effect by containing another anti-dandruff agent together with the mastic.

As an anti-dandruff agent contained in a conventional anti-dandruff shampoo composition, for example, pyroctone olamine (trade name: Octopirox (Hoechst)), zinc pyrithione (Zinc Omadine (Arch)) and urethral propy Idopropynylbutyl Carbamate (trade name: Biodocarb C 450 or Biodocarb L 450 (M & G), Omacide IPBC (Arch)) pamaraoxybenzoic acid esters, klimbazole, octopyros, ketoconazole, and the like. Use at least 1 sort (s) chosen.

The content of such antidandruff agent is 0.1 to 10.0% by weight, preferably 0.2 to 5.0% by weight based on the total composition.

Meanwhile, the shampoo composition of the present invention may contain other additives commonly used in shampoos. Examples of such components include pH adjusting agents, moisturizers, bubble promoters, viscosity adjusting agents, milk whitening agents, pearlescents, flavoring agents, colorants, preservatives, thickeners, proteins, polymers, buffers, solvents, and the like.

The shampoo composition of the present invention may have a conventional formulation, and the type and amount of these components can be easily selected by those skilled in the art.

The mastic used in the following examples used was dissolved in oil.

The present invention will be described in more detail with reference to the following examples, but the scope of the present invention is not limited to the examples.

Example

The shampoo was heated to 75 ° C. or higher to uniformly dissolve all components except mastic, cooled to 45 ° C., and mastic was added thereto.

Table 1 Preparation of Shampoo

Raw material name Example 1 Example 2 Comparative example Polyquaternium-10 0.3 0.3 0.3 Sodium laureth (3) sulfite 34 34 34 Decylglucoside 5 5 5 Coca-Amydopropyl Betaine 5 5 5 DL-panthenol 0.2 0.2 0.2 Polyquaternium-7 0.4 0.4 0.4 pH regulator 0.15 0.15 0.15 Paraoxybenzoic Acid Ester 0.2 0.2 0.2 Cocamide DEA 2.5 2.5 2.5 Aroma oil 0.5 0.5 0.5 Combination spices 2 2 2 Mastic oil 0.1 0.5 - Purified water Remaining amount Remaining amount Remaining amount

Note) 1.Unit: weight (%)

Shampoo compositions of Examples 1, 2 and Comparative Examples prepared at the composition ratios shown in Table 1 were selected for 90 people with relatively dandruff, itching and hair loss, divided into 30 groups and tested for 6 weeks. Before starting the test, triturated with a conventional shampoo and collected the dandruff accumulated for 2 days to the maximum, and the weight of the collected dandruff with the shampoo composition of Table 1 and compared the weight of dandruff accumulated for 2 days after the end of the test. The accumulated dandruff was collected directly from the scalp using a vacuum suction device, and the dandruff reduction rate was calculated by the following equation.

The anti-dandruff effect was judged to be effective only when the dandruff reduction rate was 25% or more. The results are shown in Table 2.

[Table 2] Dandruff Reduction Rate, Itching Reduction, Hair Loss Reduction

division Example 1 Example 2 Comparative example Average Dandruff Reduction (%) 23.23% 78.34% 9.18% Dandruff Reduction Effect (People) 6 10 0 No dandruff reduction effect (persons) 4 0 10 Itching decreases (persons) 3 9 One No itching reduction (persons) 7 One 9 Reduced hair loss (persons) 2 6 One No hair loss phenomenon (persons) 8 4 9

As shown in the results shown in Table 2, the shampoo of Example 1 containing 0.1% of mastic had a higher dandruff reduction rate than the shampoo of Comparative Example, which contained no more than 0.5% of Example 1 containing 0.1%. 2's shampoo showed better dandruff reduction rate.

In addition, itching was reduced in the number of people in the shampoo of Example 2 containing 0.5% mastic. Hair loss was found to decrease in the number of shampoos of Example 2 containing 0.5%, but the other shampoos do not seem to make any difference. It is expected that using more content will improve the scalp and reduce hair loss. However, it was found to be excellent for reducing dandruff and itching.

Claims (3)

In a conventional shampoo composition, Shampoo composition characterized in that it contains a mastic. The method of claim 1, Shampoo composition, characterized in that the mastic is dissolved in oil. The method according to claim 2 or 3,  Shampoo composition, characterized in that the mastic is contained in 0.1 to 10% by weight based on the total composition.