KR101257756B1 - Hair Cosmetic Compositions for Anti-Dandruff - Google Patents

Abstract

The present invention relates to a hair cosmetic composition for preventing dandruff, and to a hair cosmetic composition containing a beautiful herbaceous extract excellent in sebum secretion performance in a conventional anti-dandruff component. The anti-dandruff hair cosmetic composition according to the present invention has an excellent effect of eliminating itching of the scalp by preventing dandruff and inhibiting sebum secretion.

Beautiful herb extract, prevent dandruff, inhibit sebum secretion, remove itching of the scalp

Description

Hair Cosmetic Composition for Anti-Dandruff {Hair Cosmetic Compositions for Anti-Dandruff}

The present invention relates to a hair cosmetic composition for preventing dandruff. More specifically, the present invention relates to an anti-dandruff hair cosmetic composition capable of removing the itching of the scalp by preventing dandruff and inhibiting sebum secretion by adding a beautiful herb extract having excellent sebum secretion efficacy to the conventional anti-dandruff component.

Dandruff is a natural release of dead cells from the scalp, usually the same as on the skin. Therefore, normal dandruff is invisible and small. However, in general, dandruff means that the keratinocytes of the scalp are lumped together by sebum, sweat, etc. secreted from the scalp. This dandruff is caused by rancidated fatty acids produced by the decomposition of sebum components, stimulating scalp basal layer cells, causing cell proliferation and accompanied by itching.

Anti-dandruff agents, which are antifungal agents that have excellent bactericidal power against Pityrosporum ovale, known as the causative agent of dandruff as a scalp fungus, have a problem in human safety and their usage is legally limited, so the anti-dandruff effect is not maximized. There is a problem.

In addition, U.S. Pat.Nos. 2,809,971, 4,323,683, 4,345,080, 4,470,982, and European Patent No. 285,388 are zinc pyrithione (zinc-2-pyridinineols) which have excellent effects on scalp hyperkeratosis and antifungal activity. A shampoo composition containing -1-oxide) as an active ingredient is disclosed.

However, zinc pyrithione is a water-insoluble, high specific gravity particle having a spherical shape of about 1 μm having a very low limit of solubility of only 15 ppm in water at 25 ° C., which makes it difficult to uniformly disperse it in the hair cosmetic composition. (Gene A. Hyde and Mark M. Auerbach, Formulation Techniques for Zinc Pyrithione Antidandruff Shampoos.Cosmetics and Toiletries, 94, 57, April 1979.) The effects of a shampoo containing Zinc pyrithione on the control of dandruff.Br J Dermatol 112. 415. 1985). In particular, the skin causes contact dermatitis (Nielsen, N.H., Allergic contact dermatitis caused by zinc pyrithione associated with pustular psoriasis. Am J Contact Dermat. 8, 170, 1997), and is reported to cause problems such as environmental toxicity. Therefore, it is difficult to apply it to hair cosmetics at high concentration. Therefore, its use is limited and its content is regulated by the US Food and Drug Administration (FDA) as a matter of irritation and safety to the human body.

In addition, pyrotonolamine (2 (1H) -pyridone, 1-hydroxy-4-methyl-6- (2) that is water-soluble in water and exhibits effective anti-dandruff efficacy in order to compensate for the shortcomings of the zinc pyrithione. Hair cosmetic compositions comprising 4,4-trimethylpentyl) and 2-aminoethanol 1: 1) are known (CT, Vol. 103, 49, February, 1988). However, this ingredient, too, must be added to the hair cosmetics in order to have a sufficient effect, and its use is regulated due to safety issues to the human body (Cosmetics and Toiletries, 102, 6, Dec., 1987).

In addition, since it is an anti-dandruff agent, it is also used as an anti-dandruff agent because it shows an antimicrobial effect on microorganisms, such as climbazole, selenium sulfide and ketoconazole, which are present in the scalp.

However, there has been a report that dandruff is not completely reduced despite the reduction of the scalp microorganisms by treating the scalp with antibacterial agents. Accordingly, the present inventors have paid attention to the characteristics of phyticosporum obale, a lipophilic fungus, in order to improve such effectiveness and safety.

And dandruff usually involves itching of the scalp. This itch is thought to be caused by scalp stimulation of free fatty acids produced by rancid sebum secreted from the scalp and stimulation when the non-keratized dandruff cells detach.

In order to solve the above problems, the present invention, by adding a fine herbaceous extract excellent in sebum secretion efficacy to the conventional anti-dandruff component of Pytyrosporm Ovale known as dandruff-causing bacteria even a small amount of the conventional anti-dandruff component It is an object of the present invention to provide a hair cosmetic composition excellent in suppressing an increase in dandruff and scalp itch.

The present invention to achieve the above object,

In the hair cosmetic composition comprising a conventional anti-dandruff component, it provides a hair cosmetic composition, characterized in that it contains 0.001 to 10.0% by weight based on the total amount of the composition.

The known anti-dandruff component may be one or more selected from the group consisting of pyroctonolamine, zinc pyrithione, and iodopropynylbutyl carbamate.

The product form of the hair cosmetic composition may be a shampoo, hair conditioner, hair tonic or hair cream.

Hereinafter, the present invention will be described in detail.

In the hair cosmetics according to the present invention, the herbaceous extract and the conventional anti-dandruff ingredient are used together for the purpose of removing the scalp itching by preventing dandruff and inhibiting sebum secretion.

The present inventors pay attention to the sebum secretion inhibitory effect of the extract of the herbaceous extract to inhibit the growth of physiological dandruff causing physiological dandruff in the scalp, and oxidized with free fatty acid or lipid peroxide to stimulate the scalp to promote hyperkeratosis It has been found to inhibit the secretion of sebum that causes dandruff, thereby preventing dandruff and scalp itching.

The amount of the vinegar extract is preferably 0.001 to 10.0% by weight based on the total amount of the cosmetic composition. If the amount is less than 0.001% by weight, the effect of removing dandruff and itching of the scalp is insignificant, and when it exceeds 10.0% by weight, there is no significant effect increase.

The conventional anti-dandruff components include pyrotonolamine (trade name: Octopirox (Hoechst)), zinc pyrithione (trade name: Zinc Omadine (Arch)) and iodopropynylbutyl carbamate (trade name: Biodocarb C 450 or Biodocarb L 450 (M & G), Omacide IPBC (Arch)) and the like is used at least one selected from the group consisting of, and the content of the conventional anti-dandruff component is not limited.

Hair cosmetic compositions of the present invention may have a conventional formulation, for example, is formulated with a shampoo, hair conditioner, hair tonic, hair cream and the like. The composition of each of these formulations may contain a variety of bases and additives necessary for the formulation of the formulation and are suitable, and the type and amount of these components can be readily selected by those skilled in the art.

Hereinafter, a shampoo, a hair conditioner, a hair tonic and a hair cream containing a manufacturing method and additives which can be prepared by those skilled in the art are as follows.

<Beautiful Herb Extract Preparation>

Cannabis indica L.) is a perennial plant of the Connaceae family, grows up to 1.5 m and blooms from March to December. The flower is red.

The extract is obtained by adding 5 kg of 1,3-butylene glycol to 1 kg of fine herbaceous roots and extracting at 60 ° for 3 hours. The extract obtained at this time is a pale yellow transparent liquid with a peculiar smell.

This extract shows a characteristic absorption peak near 325 ± 2 nm when tested by absorbance measurement.

<Shampoo Manufacturing>

Shampoo is a mixture of anionic surfactants, moisturizers, hair protection ingredients, water, etc. If you have a shampoo formulation, 30% sodium lauryl sulfate, 30% sodium polyoxyethylene lauryl sulfate, palm oil fatty acid diethanolamide, ethylene glycol disulfide After adding tearate and propylene glycol to water, pyrotonolamine and iodopropynylbutyl carbamate are added to the mixture, which is then dissolved by heating and cooled. Zinc pyrithione, beetle extract, colorant, paraoxybenzoate, fragrance and citric acid are added to the mixture, mixed and cooled to prepare a shampoo.

<Hair Conditioner Manufacturing>

In the case of a hair conditioner formulation, cetanol, self-emulsifying monostearate glycerin, paraoxybenzoic acid ester, 75% distearyl dimethylammonium chloride, pyroxtonolamine are added to water, and then dissolved by heating and cooled. To this mixture is added zinc pyrithione, vinegar extract, pigment, flavor and citric acid and mixed, to prepare a hair conditioner.

<Hair tonic manufacturing>

In the case of a hair tonic formulation, oil-free hair tonic dissolves fungicides, stimulants, etc. in 30-70% alcohol solution, and adds fragrance, and oily hair tonic adds oils, etc., in which disinfectants, stimulants, and fragrances are dissolved in pure alcohol. do. Hair tonic is prepared by adding at least one selected from the group consisting of pyrotonolamine, zinc pyrithione and urethopynylbutyl carbamate, which are known anti-dandruff ingredients, to the mixture.

<Hair Cream Manufacture>

If you have a hair cream formulation, beeswax, liquid paraffin, stearic acid, lanolin, fragrances, preservatives and some other ingredients are added to the mixtures, and then the known anti-dandruff ingredients pyroctonolamine, zinc pyrithione and urethra. A hair cream is prepared by adding at least one selected from the group consisting of propynylbutyl carbamate and a beauty herb extract.

In particular, hair cosmetic compositions, such as shampoo, hair conditioner, hair tonic and hair cream may be composed of a conventional composition except for the extract of Belle.

Hereinafter, the present invention will be described in more detail with reference to the following examples, but the scope of the present invention is not limited to the examples.

[Examples 1 to 5 and Comparative Examples 1 to 5]

After adding 30% sodium lauryl sulfate, 30% polyoxyethylene lauryl sulfate, palm oil fatty acid diethanolamide, ethylene glycol distearate and propylene glycol in the composition ratio as shown in Table 1 below, the present invention was added to this mixture. Pyrotonolamine according to the addition, urido propynylbutyl carbamate was added until the temperature is 70 ℃ to dissolve uniformly and then cooled to 40 ℃. To this mixture, zinc pyrithione, beetle extract, pigment, paraoxybenzoate, fragrance and citric acid were added, mixed and cooled to prepare a shampoo.

[Table 1]

Raw material name
(weight%) Example 1 Example 2 Example 3 Example 4 Example 5
Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Sodium Lauryl Sulfate
(30%) 20.00 20.00 20.00 20.00 20.00 20.00 20.00 20.00 20.00 20.00 Polyoxyethylene
Sodium Lauryl Sulfate (30%) 30.00 30.00 30.00 30.00 30.00 30.00 30.00 30.00 30.00 30.00 Palm oil fatty acid diethanolamide 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 Ethylene Glycol Distearate 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 Propylene glycol 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 Pyrrothonol amine 0.20 - 0.20 - - - 0.20 - - - Zinc pyrichion - 0.20 - 0.20 - - 0.20 - Urethral propynylbutylcarbamate - - - - 0.20 - - - 0.20 - Beautiful herb extract 0.50 0.50 1.00 1.00 1.00 - - - - 1.00 Paraoxy
Benzoate ester 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Spices 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Citric acid 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 water Add until 100% by weight.

Anti-dandruff and scalp itching effect of the shampoo was carried out in the same manner as in Experimental Example 1 and Example 2.

[Experimental Example 1]

Fifty relatively large dandruff were selected and tested for one month on the shampoo composition as shown in Table 1. Before the start of the test, the hair was collected with a conventional shampoo and accumulated dandruff for 3 days. The weight of the collected dandruff was triturated with the shampoo composition of Table 1 and the weight of the dandruff accumulated for 3 days after the end of the test was evaluated. At this time, the accumulated dandruff was collected directly from the scalp using a vacuum suction device, and the dandruff reduction rate was calculated by the following equation.

[Equation 1]

                 Dandruff weight before start of test (mg)-Dandruff weight after start of test (mg)

Dandruff Reduction Rate (%) = -------------------------------------------- ------ X 100

                               Dandruff weight before test start (mg)

In addition, it was determined that the dandruff prevention effect is actually effective only when the dandruff reduction rate is 30% or more. The results are shown in Table 2.

[Table 2]

division Average Dandruff Reduction Rate
(%) Has anti-dandruff effect
(persons) No anti-dandruff effect
(persons) I do not know
(persons) Example 1 41.3 3 One One Example 2 56.7 4 - One Example 3 67.5 4 - One Example 4 79.9 5 - - Example 5 77.6 5 - - Comparative Example 1 2.3 - 4 One Comparative Example 2 13.1 - 3 2 Comparative Example 3 23.5 2 3 - Comparative Example 4 16.2 One 2 2 Comparative Example 5 10.8 - 4 One

[Experimental Example 2]

In order to evaluate the effect of sebum secretion, sebum secreted by Sebu tape was measured by image analysis method on the left and right sides of 50 males and 50 males, and the Sebum Excretion Rate (SER, ug / cm ² / min.) Was calculated before the test. . After applying the shampoo prepared in Table 1 to them for 30 seconds and then rinsing them for 1 month, Sebum Excretion Rate (SER) was sebum secreted with Sebu tape in the same area in the previous experiment. , ug / cm ² / min.) was calculated.

The percentage of sebum secretion according to the sebum secretion and the sample application in the steady state was determined as a sebum secretion inhibitory effect, and the results are shown in Table 3.

                     SER Before Initiation-SER One Month After Initiation

Sebum secretion inhibitory effect (%) = -------------------------------------- X 100

             SER before test start

[Table 3]

division Example 1 practice
Example 2 practice
Example 3 Example 4 practice
Example 5 compare
Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Sebum secretion inhibitory effect (%) 12 13 17 15 19 -2 -3 One 3 4

[Experimental Example 3]

Fifty men and women randomly selected from among those who felt itching were allowed to use the shampoo as shown in Table 1 once every two days for eight weeks, and then interviewed to check for relief of itching. Evaluation is based on the following criteria subjective subjective rating, and then averaged it is shown in Table 4.

* Criteria: Very good-Rating 5

Good-Rating 4

Normal-Rated 3

None-rating 2

No at all-rating 1

[Table 4]

division Example 1 Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Scalp itching effect 3.6 4.0 4.6 4.6 4.4 1.2 2.2 2.4 2.4 1.8

As can be seen in Tables 2 to 4 above, the shampoos of Examples 1 to 5, which contain the beauty extract and the conventional anti-dandruff component according to the present invention, are the shampoos of Comparative Examples 1 to 5 according to the conventional methods. Compared to the anti-dandruff, sebum secretion effect and itching removal effect was found to be excellent.

[Examples 6 to 10 and Comparative Examples 6 to 10]

After adding cetanol, self-emulsifying monostearic acid ester, paraoxybenzoic acid ester, 75% distearyl dimethylammonium chloride, pyrotonolamine, and iodopropynylbutyl carbamate in the composition ratio as shown in Table 4 below, The mixture was warmed to a temperature of 65 ° C., dissolved uniformly, and cooled to 40 ° C. Subsequently, zinc pyrithione, beetle extract, colorant, flavoring, and citric acid were added to the mixture and mixed, to prepare a hair conditioner.

[Table 5]

Raw material name (% by weight) Example 6 Example 7 Example 8 Example 9 Example 10 Comparative Example 6 Comparative Example 7 Comparative Example 8 Comparative Example 9 Comparative Example 10 Cetanol 3.0 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 Self-emulsification
Monostearic acid
glycerin 1.50 1.50 1.50 1.50 1.50 1.50 1.50 1.50 1.50 1.50 Distearyl chloride
Dimethylammonium (75%) 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 Propylene glycol 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 Pyrrothonol amine 0.20 - 0.20 - - - 0.20 - - - Zinc pyrichion - 0.20 - 0.20 - - 0.20 - Urethral propynylbutylcarbamate - - - - 0.20 - - - 0.20 - Beautiful herb extract 0.50 0.50 1.00 1.00 1.00 - - - - 1.00 Paraoxy
Benzoate ester 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Spices 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Citric acid 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 water Add until 100% by weight.

The anti-dandruff effect of the hair conditioner was carried out in the same manner as in Experimental Example 3.

[Experimental Example 4]

50 relatively high dandruff were selected and tested for 1 month on the hair conditioner prepared as shown in Table 4. Before starting the test, wash with a conventional shampoo and use a conventional hair conditioner, collect the dandruff accumulated for 3 days, triturate with the weight of the collected dandruff and the usual shampoo, and use the hair conditioner composition of Table 4 The weight of dandruff accumulated daily was compared and the results are shown in Table 5.

TABLE 6

division Average Dandruff Reduction Rate
(%) Has anti-dandruff effect
(persons) No anti-dandruff effect
(persons) I do not know
(persons) Example 6 44.6 4 One - Example 7 62.5 4 - One Example 8 63.5 4 One - Example 9 83.9 5 - - Example 10 82.2 5 - - Comparative Example 6 5.8 - 3 2 Comparative Example 7 12.4 One One 3 Comparative Example 8 28.3 One One 3 Comparative Example 9 20.7 - 2 3 Comparative Example 10 11.9 - 4 One

As can be seen in Table 5 above, the hair conditioner of Examples 6 to 10, which contains the beauty extract and the conventional anti-dandruff component according to the present invention, the hair conditioner of Comparative Examples 6 to 10 according to a conventional method Compared to the anti-dandruff effect was found to be excellent.

As described above, the anti-dandruff hair cosmetic composition according to the present invention is a useful invention having the effect of removing dandruff and itching of the scalp by adding a beautiful herbaceous extract excellent in sebum production inhibitory effect to a conventional anti-dandruff component.

While the invention has been described in detail above with reference to the described embodiments, it will be apparent to those skilled in the art that various modifications and variations are possible within the scope and spirit of the invention, and such modifications and variations fall within the scope of the appended claims. It is also natural.

Claims (3)

In the anti-dandruff hair cosmetic composition containing a conventional anti-dandruff component, the hair cosmetic composition comprising 0.001 to 10.0% by weight of the extract of fine beauty. The hair cosmetic composition according to claim 1, wherein the anti-dandruff component is at least one member selected from the group consisting of pyrotonolamine, zinc pyrithione and urethopynylbutyl carbamate. The hair cosmetic composition according to claim 1, which is a shampoo, hair conditioner, hair tonic or hair cream.