KR0174807B1 - Hair treatment having anti-dandruff function - Google Patents

Abstract

The present invention relates to a hair cosmetic composition having an anti-dandruff effect, and more particularly, tea tree oil containing terpinen-4-ol (Terpinen-4-ol) as an active ingredient having bactericidal and antimicrobial activity against dandruff ( Tea Tree Oil (oil of Melaleuca alternifolia) or zinc pyrithione or salicylic acid, which is a well-known antidandruff agent, can continuously provide anti-dandruff and itching effects without causing hypoallergenic stability problems to the human body. It is to provide a hair cosmetic composition that can be.

Description

Hair cosmetic composition having anti-dandruff effect

The present invention relates to a hair cosmetic composition having an anti-dandruff effect, and more particularly, tea tree oil containing terpinen-4-ol (Terpinen-4-ol) as an active ingredient having bactericidal and antimicrobial activity against dandruff ( It contains Tea Tree Oil (oil of Melaleuca alternifolia) or contains zinc pyrithione or salicylic acid, which is a known antidandruff agent, to continuously provide anti-dandruff and itching effects without causing hypoallergenic stability problems to the human body. It is to provide a hair cosmetic composition that can be.

In general, dandruff refers to the stratum corneum-like mass formed by the dead or peeled cells of the scalp caused by the active metabolism of the human body with the secretion of the scalp sebaceous glands. Dandruff gradually has a clear border with normal skin, becomes red, and increases the scale of the scalp, which usually leads to seborrheic dermatitis with itching and inflammation.

The root cause of such severe dandruff is still unclear, but in general, neurological factors such as endocrine hormone imbalance, metabolic imbalance, stress, biochemical changes in epithelial tissue due to excessive proliferation of scalp cells, It is known to be due to the combined effects of several factors, such as the growth and activity of scalp microorganisms, inflammation caused by air pollution.

In particular, the proliferation and activity of microorganisms called Pityrosporum Ovale, which are present in unclean scalp, have been recognized for a long time as a major factor for worsening dandruff and itching, and are widely accepted in recent years.

Therefore, in the case of hair cosmetics having a dandruff inhibitory action for the purpose of the treatment and prevention of dandruff and itching, the main cause of dandruff is effectively inhibit the growth and activity of microbial phytirosporum obale and abnormal metabolic activity of the scalp cells. It is essential to contain a component that can be normalized.

Thus, as an example of the hair cosmetic composition aimed at suppressing dandruff and itching, the hair cosmetic composition containing zinc pyrithione (zinc-2-pyridinezol-1-oxide) as an active ingredient is mentioned. (US Pat. No. 2,809,971, US Pat. No. 4,323,683, US Pat. No. 4,345,080, US Pat. No. 4,470,982, and European Patent No. 285,388.) However, zinc pyrithione has a solubility of only 15 ppm in 25 ° C water. It is a water-insoluble solid particle having a spherical shape of about 1 μm having a very low limit. It is separated from the hair cosmetic composition, especially a shampoo composition, which mainly consists of water-soluble substrates, causing sedimentation by precipitation and the like. As a matter of stability, the content is regulated by the domestic agency and the US Food and Drug Administration (FDA).

Thus, the present inventors have repeatedly studied to provide a hair cosmetic composition that can not continuously cause a safety problem to the human body and obtain a dandruff inhibitory effect, the main cause of dandruff occurrence is phytirosporm Ovalle The present invention has been completed by paying attention to the fact that terpinen-4-ol having a bactericidal and antimicrobial effect is present in a large amount in Tea Tree Oil (Oil of Melaleu ca alternifolia).

Accordingly, it is an object of the present invention to provide a hair cosmetic composition that can provide an anti-dandruff and itching effect without causing a problem of stability to the human body with low irritation.

In order to achieve the above object, the hair cosmetic composition according to the present invention has a tea tree oil of 0.01 to the total weight of the composition. 10 weight It is characterized by containing in the amount of.

Other objects and applications of the present invention will become apparent from the following detailed description.

Hereinafter, the present invention will be described in more detail.

Tea tree oil used as an active ingredient exhibiting an anti-dandruff effect in the present invention is an oil obtained by steam distillation of leaves of Melaleuca alternifolia, a species of Australian Myrtaceae.

This tea tree oil contains terpinen-4-ol, pinene, Terpinene ( -terpinene), Terpinene ( terpinene, terpinolene, Terpineol ( -terpineol), 1,8-cineol (1,8-cineol) and 50 components, among these components tea tree oil 30.0 to the active ingredient terpinene-4-ol component 40.0 weight As it contains, it has bactericidal and antimicrobial activity against microorganisms such as pathogenic fungi, Escherichia coli and Staphylococcus bacteria which cause eczema and scabies existing on the skin and scalp. In particular, it can suppress the growth and activity of microorganisms called Pityrospourm Ovale, a major cause of aggravation of dandruff and itching, and relieve irritation, erythema and seborrheic inflammation.

Tea tree oil used in the present invention can be prepared according to a conventional method, for example, by separating the solution obtained by extracting the leaves of the tea tree by steam distillation.

Tea tree oil used in the hair cosmetic composition of the present invention is 0.01 to the total weight of the composition 10 weight In the amount of, preferably 0.1 6 weight It is used in the amount of. Tea tree oil contains 0.01 weight Less than 10, no satisfactory effect is obtained. In case of abnormality, anti-dandruff effect cannot be obtained due to excessive growth of scalp microorganisms.

The hair cosmetic composition of the present invention may have a conventional formulation, for example, may be formulated with shampoo, rinse, hair tonic and the like. The composition of each of these formulations may contain a variety of bases and additives necessary for the formulation of the formulation and are suitable, and the types and amounts of these components can be readily selected by those skilled in the art. Below, representative base shampoo compositions of the hair cosmetic composition will be described, for example, representative base components and additives.

The hair cosmetic composition, especially the shampoo composition, according to the present invention may be composed of a conventional shampoo composition except for tea tree oil, which is an active ingredient. In addition, in order to increase the anti-dandruff effect, zinc pyrithione, which inhibits the growth of microorganisms and increase in activity, salicylic acid and its salts, which remove dandruff by the exfoliation action, does not adversely affect the composition of the present invention. It can be used in combination in amounts that do not cause irritation to the human body.

The essential components and optional components constituting the shampoo composition of the present invention will be described in more detail below.

[Surfactants]

Synthetic surfactants used in the present invention may be any selected from anionic, amphoteric, nonionic and cationic surfactants, the surfactant is 10 to the total weight of the composition 70 weight , Preferably 10 30 weight , Most preferably 10 Used in amounts of 20% by weight.

Synthetic anionic surfactants that can be used in the present invention are alkyl and alkyl ether sulfates, represented by the following formula (1).

Wherein R is 10 carbon atoms Is an alkyl group of 22, and n is 0 Is an integer of 4 and M is selected from water-soluble cations such as ammonium, sodium, triethanolamine. Preferably, R has 12 carbon atoms 16 alkyl alkyl sulfates and alkyl ether sulfates are preferred.

Alcohols can be derived from or synthesized from fats such as palm oil or tallow. In the present invention, lauryl alcohol and straight chain alcohol derived from palm oil are preferable. These alcohols ethylene oxide about 1 4 moles, in particular 3 moles, are reacted and neutralized, for example, in the resulting mixture in the molecule having an average of 3 moles of ethylene oxide per mole of alcohol. Specific examples thereof include sodium lauryl sulfate, lauryl ammonium sulfate, lauryl triethanolamine, sodium polyoxyethylene lauryl sulfate, and polyoxyethylene lauryl sulfate.

Synthetic amphoteric surfactants are alkylbetaines and alkylamidopropylbetaines, represented by formulas (2) and (3).

In said formula, R <_1> has 8 carbon atoms It is an alkyl group of 18, and R <_2> CO is C8 It is an alkoxy group of 18. Specific examples include cocodimethylcarboxymethylbetaine, lauryldimethylcarboxymethylbetaine, lauryldimethyl -Carboxyethyl betaine, cetyl dimethyl carboxymethyl, cocoamido propyl betaine and the like.

Synthetic nonionic surfactants are represented by Formulas 4 and 5 as alkanolamides and alkylamine oxides.

In said formula, R <_1> has 8 carbon atoms An alkyl group of 18, and R ₂ and R ₃ have 1 carbon 3 alkyl groups, R ₄ CO is 8 carbon atoms 16 is an alkoxy group, n is 0 or 1; Specific examples include lauryl diethylamine oxide, palm oil alkyldimethylamine oxide, lauric acid diethanolamide, palm oil fatty acid diethanolamide, palm oil fatty acid monoethanol amide, and the like.

The above-mentioned surfactants can be selectively used alone or in combination in the hair cosmetic composition of the present invention.

[Optional ingredients]

The optional ingredients used in the compositions of the present invention are well known to those skilled in the art as customary optional ingredients for maintaining basic physical properties and quality. As specific examples, pearlescent aids, preservatives, thickeners, viscosity regulators, pH regulators, perfumes, dyes, hair conditioning agents are used.

Pearlescent aids such as, for example, ethylene glycol, monostearate, ethylene glycol distearate; Preservatives such as methyl paraoxybenzoate, methylchloroisothiazolinone and methylisothiazolinone; Viscosity modifiers such as sodium chloride, ammonium chloride, propylene glycol; PH adjusters such as citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide; Hair conditioning agents such as polyquaternium-10, polyquaternium-7, methylpolysiloxane, dimethylconcopolyol, hydrolyzed animal protein; Dyestuffs such as water soluble tars are used, and perfumes may be used.

Hair cosmetic composition according to the present invention can be used according to a conventional method of use, the number of times of use can be varied according to the user's scalp state or taste.

Hereinafter, the hair cosmetic composition of the present invention will be described in more detail with reference to examples of the present invention, but the present invention is not limited to these examples.

Example 1 7 and Comparative Example 1

[Test Example 1]

[Antibacterial activity comparison test]

The test bacteria were streaked on the agar plates containing the shampoos of the comparative examples and examples according to the concentrations, and the dandruff-causing bacteria were incubated for 2 days under aerobic conditions, followed by observing the growth of bacteria and the lowest inhibition of the growth of test bacteria. The concentration (MIC) was measured to confirm the antimicrobial activity against the cause of dandruff.

Test bacteria

Dandruff causing bacteria: Pityrosprum ovale ATCC 12087

2. Medium used

Blood agar medium (blood agar base + final concentration 5 Amount, blood), BHI agar

As can be seen from Table 1, Example 1 containing the tea tree oil of the present invention In the hair cosmetic composition of 7, it can be seen that the MIC decreases against dandruff, and that the degree of MIC decrease is excellent as the content of tea tree oil increases. Thus, the composition of the present invention can be effectively used for the prevention of dandruff production, dandruff treatment and alleviation.

The reduction of MIC was greatest in Examples 4, 6, and 7 using zinc pyrithione or salicylic acid, which are known antidandruff agents, together with the hair cosmetic composition of the present invention.

[Test Example 2]

[Dandruff Reduction Effect Test]

19 more dandruff 54 men of 35 years old were selected and tested for 1 month in 9 groups of 6 people for each Example and Comparative Example, and the results are shown in Table 2.

Trituration with a normal shampoo before the start of the test, and collected the dandruff accumulated for three days after the three-time hair and the weight of the collected dandruff and three times every two days with the hair cosmetic composition of each Example and Comparative Example accumulates three days after the end of the test The weight of the isolated dandruff was evaluated. At this time, the accumulated dandruff was collected directly from the scalp with a vacuum suction device, and the dandruff reduction rate was calculated based on the following equation.

As shown in Table 2, in the embodiment containing the tea tree oil of the present invention, the average dandruff reduction rate is high, and as the content of tea tree oil increases, the dandruff suppression effect is excellent. In addition, as in Examples 4, 6 and 7, it can be seen that the anti-dandruff inhibitor effect is further improved when it contains a combination of known anti-dandruff zinc pyrithione or salicylic acid.

[Test Example 3]

[Scalp Itching Prevention Test]

56 men who felt relatively itching were selected and the shampoos of each example and the comparative example were divided into seven groups of eight people for two months and the results are shown in Table 3.

[Evaluation standard]

Very itchy 1 point

Slightly itchy 2 points

is average 3 points

Alright 4 points

Not itchy 5 points

As shown in Table 3, it can be seen that the effect of removing the scalp itch in the Example containing tea tree oil of the present invention. Moreover, as the content of tea tree oil is increased, it can be seen that the effect of removing the scalp itch when using zinc pyrithione or salicylic acid together.

As can be seen from the above description, tea tree oil containing a large amount of terpinene-4-ol as an active ingredient, capable of inhibiting the growth and activity of the dandruff phytirosporum obale, is effective in reducing dandruff and itching. It shows a great effect, and when combined with a known anti-dandruff agent zinc pyrithione or salicylic acid, synergism between each other shows much better dandruff and itching suppression effect.

Claims (3)

In the hair cosmetic composition, tea tree oil is 0.01 to the total weight of the composition. 10 weight Hair cosmetic composition having an anti-dandruff effect, which is contained in an amount of. The hair cosmetic composition of claim 1, wherein the tea tree oil is a solution obtained by extracting the leaves of Melaleuca alterni folia by steam distillation. The hair cosmetic composition according to claim 1, further comprising zinc pyrithione or salicylic acid.