KR20080080651A - 항염증성 ｄａｂ - Google Patents
항염증성 ｄａｂ Download PDFInfo
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- KR20080080651A KR20080080651A KR1020087017659A KR20087017659A KR20080080651A KR 20080080651 A KR20080080651 A KR 20080080651A KR 1020087017659 A KR1020087017659 A KR 1020087017659A KR 20087017659 A KR20087017659 A KR 20087017659A KR 20080080651 A KR20080080651 A KR 20080080651A
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
Landscapes
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| AU2005907124A AU2005907124A0 (en) | 2005-12-20 | Anti-inflammatory dAb | |
| AU2005907124 | 2005-12-20 | ||
| US81727206P | 2006-06-28 | 2006-06-28 | |
| US60/817,272 | 2006-06-28 |
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| KR20080080651A true KR20080080651A (ko) | 2008-09-04 |
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| AU (2) | AU2006326937B2 (enExample) |
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| RU2008110060A (ru) * | 2005-08-15 | 2009-09-27 | Арана Терапьютикс Лимитед (Au) | Сконструированные антитела с каркасными участками приматов нового света |
| WO2007070979A1 (en) * | 2005-12-20 | 2007-06-28 | Arana Therapeutics Limited | Chimeric antibodies with part new world primate binding regions |
| WO2007087673A1 (en) | 2006-02-01 | 2007-08-09 | Arana Therapeutics Limited | Domain antibody construct |
| US20080139790A1 (en) * | 2006-12-08 | 2008-06-12 | Jennings Philip A | Chimeric antibodies |
| US20110319597A1 (en) * | 2008-08-14 | 2011-12-29 | Caphalon Australia Pty. Ltd. | Variant domain antibodies |
| CN104013724A (zh) * | 2014-06-20 | 2014-09-03 | 苏州法莫生物技术有限公司 | 一种改善睡眠的中药组合物 |
| DK4089113T3 (da) | 2015-03-31 | 2024-02-05 | Sorriso Pharmaceuticals Inc | Polypeptider |
| KR102789821B1 (ko) | 2015-03-31 | 2025-04-02 | 소리소 파마슈티컬스 인크. | 프로테아제-절단가능 링커를 갖는 펩티드 구조물 |
| CA2981103A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptides |
| EP3519438A1 (en) | 2016-09-30 | 2019-08-07 | VHsquared Limited | Compositions |
| CN107469069A (zh) * | 2017-08-18 | 2017-12-15 | 四川普莱美生物科技集团有限公司 | 恒河猴肺纤维化模型的造模方法、制剂、制剂的制备方法、恒河猴肺纤维化模型及其应用 |
| CN110003330B (zh) * | 2019-04-12 | 2022-09-09 | 深圳普瑞金生物药业股份有限公司 | TNF-α单域抗体、核酸分子及试剂盒 |
| EP3986571A1 (en) | 2019-06-21 | 2022-04-27 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| AU2020296979A1 (en) | 2019-06-21 | 2022-02-24 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
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| DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| US5994510A (en) | 1990-12-21 | 1999-11-30 | Celltech Therapeutics Limited | Recombinant antibodies specific for TNFα |
| GB9109645D0 (en) | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| EP0605442B1 (en) * | 1991-07-25 | 2003-04-16 | Idec Pharmaceuticals Corporation | Recombinant antibodies for human therapy |
| AU728657B2 (en) | 1996-03-18 | 2001-01-18 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US6225290B1 (en) * | 1996-09-19 | 2001-05-01 | The Regents Of The University Of California | Systemic gene therapy by intestinal cell transformation |
| US6277375B1 (en) * | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| ES2694002T3 (es) | 1999-01-15 | 2018-12-17 | Genentech, Inc. | Polipéptido que comprende una región Fc de IgG1 humana variante |
| US7235643B2 (en) | 2000-11-07 | 2007-06-26 | Morphotek, Inc. | Antibodies and methods for generating genetically altered antibodies with high affinity |
| GB0029407D0 (en) | 2000-12-01 | 2001-01-17 | Affitech As | Product |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| GB0114856D0 (en) * | 2001-06-18 | 2001-08-08 | Medical Res Council | Selection by avidity capture |
| US20050271663A1 (en) | 2001-06-28 | 2005-12-08 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| US20060073141A1 (en) | 2001-06-28 | 2006-04-06 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| JP2005538706A (ja) * | 2001-07-12 | 2005-12-22 | ジェファーソン フーテ， | スーパーヒト化抗体 |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| SI1527100T1 (sl) * | 2002-03-29 | 2009-12-31 | Schering Corp | Humana monoklonska protitelesa proti interlevkinu-5 in postopki in sestavki, ki jih obsegajo |
| US7696320B2 (en) | 2004-08-24 | 2010-04-13 | Domantis Limited | Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor |
| US20080241166A1 (en) | 2002-06-28 | 2008-10-02 | Domantis Limited | Ligands that bind a receptor |
| US20060034845A1 (en) * | 2002-11-08 | 2006-02-16 | Karen Silence | Single domain antibodies directed against tumor necrosis factor alpha and uses therefor |
| GB0230201D0 (en) * | 2002-12-27 | 2003-02-05 | Domantis Ltd | Retargeting |
| GB0230203D0 (en) * | 2002-12-27 | 2003-02-05 | Domantis Ltd | Fc fusion |
| EP1578801A2 (en) | 2002-12-27 | 2005-09-28 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| ES2327409T3 (es) * | 2003-03-26 | 2009-10-29 | Apogenix Gmbh | Proteinas de fusion fc mejoradas. |
| CA2525120C (en) * | 2003-05-14 | 2013-04-30 | Domantis Limited | A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire |
| EP1660655B1 (en) | 2003-06-27 | 2016-11-02 | Bioren, LLC | Look-through mutagenesis |
| CA2529819A1 (en) | 2003-06-30 | 2004-09-23 | Domantis Limited | Pegylated single domain antibodies |
| AR042955A1 (es) * | 2003-07-18 | 2005-07-13 | Amgen Inc | Agentes de union especifica al factor de crecimiento de hepatocitos |
| CA2543631A1 (en) | 2003-11-07 | 2005-05-26 | Amgen Inc. | Monkey immunoglobulin sequences |
| WO2005052002A2 (en) * | 2003-11-20 | 2005-06-09 | Massachusetts Institute Of Technology | Single-domain antibodies and uses thereof |
| EP2275448A3 (en) | 2003-12-19 | 2013-02-06 | Genentech, Inc. | Monovalent antibody fragments useful as therapeutics |
| WO2005087810A2 (en) | 2004-03-08 | 2005-09-22 | Zymogenetics, Inc. | Dimeric fusion proteins and materials and methods for producing them |
| US6979473B2 (en) | 2004-03-15 | 2005-12-27 | Boston Scientific Scimed, Inc. | Method for fine bore orifice spray coating of medical devices and pre-filming atomization |
| BRPI0511448A (pt) | 2004-07-06 | 2007-12-26 | Bioren Inc | anticorpos anti-tnf-alfa de alta afinidade, método para a geração dos mesmos e biblioteca de seqüências |
| US7678371B2 (en) | 2005-03-04 | 2010-03-16 | Biogen Idec Ma Inc. | Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues |
| US8008443B2 (en) | 2005-04-26 | 2011-08-30 | Medimmune, Llc | Modulation of antibody effector function by hinge domain engineering |
| CA2605781A1 (en) * | 2005-05-09 | 2007-04-12 | Glycart Biotechnology Ag | Antigen binding molecules having modified fc regions and altered binding to fc receptors |
| RU2008110060A (ru) | 2005-08-15 | 2009-09-27 | Арана Терапьютикс Лимитед (Au) | Сконструированные антитела с каркасными участками приматов нового света |
| WO2007070979A1 (en) * | 2005-12-20 | 2007-06-28 | Arana Therapeutics Limited | Chimeric antibodies with part new world primate binding regions |
| WO2007087673A1 (en) | 2006-02-01 | 2007-08-09 | Arana Therapeutics Limited | Domain antibody construct |
| WO2007092772A2 (en) | 2006-02-03 | 2007-08-16 | Medimmune, Inc. | Protein formulations |
| BRPI0710011A2 (pt) | 2006-04-14 | 2011-08-02 | Trubion Pharmaceuticals Inc | proteìnas de ligação compreendendo articulação de imunoglobulina e regiões fc dotadas de funções efetoras fc alteradas |
| US20080139790A1 (en) | 2006-12-08 | 2008-06-12 | Jennings Philip A | Chimeric antibodies |
| CA2682605A1 (en) * | 2007-04-18 | 2008-10-30 | Zymogenetics, Inc. | Single chain fc, methods of making and methods of treatment |
| US20110077383A1 (en) | 2007-07-03 | 2011-03-31 | Medimmune, Llc | Hinge domain engineering |
| EP2615115A3 (en) | 2007-11-30 | 2014-01-08 | Glaxo Group Limited | Antigen-binding constructs |
| AU2009206149B2 (en) * | 2008-01-16 | 2013-07-18 | Mars, Incorporated | Automated systems for feeding animals and collecting animal excrement |
| EP2899209A1 (en) | 2008-04-29 | 2015-07-29 | Abbvie Inc. | Dual Variable Domain Immunoglobulins and uses thereof |
| KR20110020860A (ko) | 2008-05-23 | 2011-03-03 | 알리바 바이오파마수티컬스, 아이엔씨. | 유전자 삽입동물에서 단일 ｖｌ 도메인 항체를 생산하는 방법 |
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2012
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Also Published As
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| WO2007070948A1 (en) | 2007-06-28 |
| EA200870072A1 (ru) | 2009-04-28 |
| EA017710B1 (ru) | 2013-02-28 |
| US20110237780A1 (en) | 2011-09-29 |
| US20130040383A1 (en) | 2013-02-14 |
| US20090286962A1 (en) | 2009-11-19 |
| WO2007070979A1 (en) | 2007-06-28 |
| EP1969010A1 (en) | 2008-09-17 |
| JP2009519983A (ja) | 2009-05-21 |
| AU2006326937A1 (en) | 2007-06-28 |
| US20090226428A1 (en) | 2009-09-10 |
| AU2006326867A1 (en) | 2007-06-28 |
| JP2009519720A (ja) | 2009-05-21 |
| EP1969009A4 (en) | 2009-07-22 |
| EP1969010A4 (en) | 2009-07-22 |
| US7981414B2 (en) | 2011-07-19 |
| JP5179374B2 (ja) | 2013-04-10 |
| US8263076B2 (en) | 2012-09-11 |
| CA2634080A1 (en) | 2007-06-28 |
| AU2006326937B2 (en) | 2012-01-19 |
| CA2634083A1 (en) | 2007-06-28 |
| EP1969009A1 (en) | 2008-09-17 |
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