KR20080059337A - 경구용 항미생물성 제약학적 조성물 - Google Patents

경구용 항미생물성 제약학적 조성물 Download PDF

Info

Publication number
KR20080059337A
KR20080059337A KR1020087012947A KR20087012947A KR20080059337A KR 20080059337 A KR20080059337 A KR 20080059337A KR 1020087012947 A KR1020087012947 A KR 1020087012947A KR 20087012947 A KR20087012947 A KR 20087012947A KR 20080059337 A KR20080059337 A KR 20080059337A
Authority
KR
South Korea
Prior art keywords
pharmaceutical composition
pharmaceutical compositions
active ingredient
matrix
colon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020087012947A
Other languages
English (en)
Korean (ko)
Inventor
마우로 아이아니
로베르타 보젤라
쥬세페 세라스코
로베르토 빌라
Original Assignee
코스모 테크놀러지스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 코스모 테크놀러지스 리미티드 filed Critical 코스모 테크놀러지스 리미티드
Publication of KR20080059337A publication Critical patent/KR20080059337A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • A61K9/2826Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1020087012947A 2004-06-25 2005-05-03 경구용 항미생물성 제약학적 조성물 Withdrawn KR20080059337A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001295A ITMI20041295A1 (it) 2004-06-25 2004-06-25 Composizioni farmaceutiche antimicrobiche orali
ITMI2004A001295 2004-06-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020067027024A Division KR101157486B1 (ko) 2004-06-25 2005-05-03 경구용 항미생물성 제약학적 조성물

Publications (1)

Publication Number Publication Date
KR20080059337A true KR20080059337A (ko) 2008-06-26

Family

ID=34968899

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020087012947A Withdrawn KR20080059337A (ko) 2004-06-25 2005-05-03 경구용 항미생물성 제약학적 조성물
KR1020067027024A Expired - Lifetime KR101157486B1 (ko) 2004-06-25 2005-05-03 경구용 항미생물성 제약학적 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020067027024A Expired - Lifetime KR101157486B1 (ko) 2004-06-25 2005-05-03 경구용 항미생물성 제약학적 조성물

Country Status (22)

Country Link
US (9) US8486446B2 (https=)
EP (2) EP1763339B1 (https=)
JP (2) JP5026262B2 (https=)
KR (2) KR20080059337A (https=)
CN (2) CN1976685B (https=)
AT (1) ATE392889T1 (https=)
CA (2) CA2569683C (https=)
CY (1) CY1108196T1 (https=)
DE (1) DE602005006278T2 (https=)
DK (1) DK1763339T3 (https=)
ES (1) ES2303255T3 (https=)
FI (1) FIC20190031I1 (https=)
HR (1) HRP20080252T3 (https=)
HU (1) HUS1900037I1 (https=)
IT (1) ITMI20041295A1 (https=)
MX (1) MXPA06014698A (https=)
PL (1) PL1763339T3 (https=)
PT (1) PT1763339E (https=)
RS (1) RS50581B (https=)
SI (1) SI1763339T1 (https=)
WO (1) WO2006003043A1 (https=)
ZA (1) ZA200610577B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220165913A (ko) * 2021-06-09 2022-12-16 강원대학교산학협력단 경구 투여용 나노입자 및 이의 제조방법

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
EP2011486B2 (en) 2007-07-06 2015-08-12 Lupin Ltd. Pharmaceutical compositions of rifaximin
WO2009037264A2 (en) * 2007-09-17 2009-03-26 Da Volterra Colonic delivery of antimicrobial agents
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
US9006288B2 (en) 2009-01-12 2015-04-14 Biokier, Inc. Composition and method for treatment of diabetes
RS56054B1 (sr) 2009-01-12 2017-09-29 Biokier Inc Smeša i metod za lečenje dijabetesa
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
CN102711800A (zh) 2009-09-23 2012-10-03 拜奥基尔公司 治疗糖尿病的组合物和方法
WO2012016707A2 (en) * 2010-08-06 2012-02-09 Ratiopharm Gmbh Oral dosage form for the modified release of dimebolin
US20130259947A1 (en) * 2010-11-29 2013-10-03 Dr. Reddy's Laboratories Ltd. Oral metronidazole pharmaceutical compositions
PL3706724T3 (pl) 2017-11-10 2024-12-16 Cosmo Technologies Ltd. Doustne kompozycje ryfamycyny sv
IT202000005782A1 (it) 2020-03-18 2021-09-18 Dpl Pharma S P A Formulazioni farmaceutiche a rilascio controllato per il trattamento di infezioni intestinali

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458505B (sv) * 1979-07-10 1989-04-10 Lepetit Spa Anvaendningen av rifamycin sv och salter daerav foer framstaellning av en beredning foer behandling av reumatoid artrit samt vissa av salterna och deras framstaellning
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
IE61651B1 (en) 1990-07-04 1994-11-16 Zambon Spa Programmed release oral solid pharmaceutical dosage form
IT1260505B (it) * 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon
CN1097306A (zh) * 1993-07-12 1995-01-18 中国医科大学第二临床学院 复方抗炎栓剂
US5849327A (en) 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US6245351B1 (en) * 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
US5985823A (en) * 1997-06-09 1999-11-16 Ambi Inc. Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon
WO1999001121A1 (en) * 1997-07-01 1999-01-14 Pfizer Inc. Sertraline salts and sustained-release dosage forms of sertraline
DE19850445A1 (de) 1998-11-02 2000-05-04 Falk Pharma Gmbh Arzneimittel zur topischen Behandlung entzündlicher Darmerkrankungen
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB9910773D0 (en) 1999-05-11 1999-07-07 West Pharm Serv Drug Res Ltd Novel single unit coated dosage forms that can be used to minimise the effect of food on the absorption of drugs from the gastrointestinal tract
EP1183014B1 (en) 1999-06-14 2003-10-08 Cosmo S.p.A. Controlled release and taste masking oral pharmaceutical compositions
JP4393098B2 (ja) * 2002-06-21 2010-01-06 独立行政法人科学技術振興機構 アンサマイシン系抗生物質の新規用途及び新規血管新生抑制物質のスクリーニング方法
CN1201736C (zh) * 2002-07-19 2005-05-18 安徽省药物研究所 甲硝唑结肠定位缓释制剂
EP1545516B1 (en) 2002-08-26 2008-09-03 S.L.A. Pharma AG Topical formulation comprising at least 10% of metronidazole in white petrolatum and its use in the anal and rectal region
WO2005030173A1 (en) * 2003-09-25 2005-04-07 Ranbaxy Laboratories Limited Colon-specific drug delivery using interpolymer complexations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220165913A (ko) * 2021-06-09 2022-12-16 강원대학교산학협력단 경구 투여용 나노입자 및 이의 제조방법

Also Published As

Publication number Publication date
HRP20080252T3 (hr) 2008-07-31
DE602005006278D1 (de) 2008-06-05
WO2006003043A1 (en) 2006-01-12
ES2303255T3 (es) 2008-08-01
JP2008163038A (ja) 2008-07-17
ATE392889T1 (de) 2008-05-15
MXPA06014698A (es) 2007-03-26
US8263120B2 (en) 2012-09-11
US20140370093A1 (en) 2014-12-18
US20120316228A1 (en) 2012-12-13
EP1894560A1 (en) 2008-03-05
CY1108196T1 (el) 2014-02-12
US20070248664A1 (en) 2007-10-25
PL1763339T3 (pl) 2008-10-31
RS50581B (sr) 2010-05-07
DE602005006278T2 (de) 2009-10-08
JP2008503540A (ja) 2008-02-07
KR20070028441A (ko) 2007-03-12
ZA200610577B (en) 2008-07-30
US20080233193A1 (en) 2008-09-25
US20130004569A1 (en) 2013-01-03
HUS1900037I1 (hu) 2019-07-29
US8529945B2 (en) 2013-09-10
EP1763339A1 (en) 2007-03-21
US20210093576A1 (en) 2021-04-01
FIC20190031I1 (fi) 2019-05-28
DK1763339T3 (da) 2008-08-11
US8741948B2 (en) 2014-06-03
US20120207834A1 (en) 2012-08-16
SI1763339T1 (sl) 2008-08-31
ITMI20041295A1 (it) 2004-09-25
CA2569683C (en) 2012-04-03
KR101157486B1 (ko) 2012-07-09
CN1976685B (zh) 2011-05-18
CA2628005A1 (en) 2006-01-12
CN101317826A (zh) 2008-12-10
CA2569683A1 (en) 2006-01-12
US20120316229A1 (en) 2012-12-13
US8486446B2 (en) 2013-07-16
US20190192441A1 (en) 2019-06-27
JP5026262B2 (ja) 2012-09-12
EP1763339B1 (en) 2008-04-23
PT1763339E (pt) 2008-06-19
CN1976685A (zh) 2007-06-06

Similar Documents

Publication Publication Date Title
US8529945B2 (en) Oral antimicrobial pharmaceutical compositions
US20140186450A1 (en) Gastroresistant pharmaceutical formulations containing rifaximin
JP5918242B2 (ja) リファキシミンを含む医薬処方物、それを得るための方法及び腸疾患を治療する方法
EP0983079B1 (en) A method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon
US20130259947A1 (en) Oral metronidazole pharmaceutical compositions
US5958873A (en) Oral formulation for treatment of bacteria-induced diseases of the colon
EA010199B1 (ru) Антимикробная композиция для перорального введения
US20100203125A1 (en) Synergistic antibacterial formulation and a method of making the same
US20100272794A1 (en) Pharmaceutical composition of memantine
AU2008243202B2 (en) Oral antimicrobial pharmaceutical compositions
KR20110098565A (ko) 일라프라졸, 항생물질 및/또는 유산균을 포함하는 위장질환을 예방 또는 치료하기 위한 경구용 약제 조성물
HK40060877A (en) Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20080529

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid