KR20070122525A - 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을갖는 멀티플렉스 형광 검출 장치 - Google Patents

통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을갖는 멀티플렉스 형광 검출 장치 Download PDF

Info

Publication number
KR20070122525A
KR20070122525A KR1020077025262A KR20077025262A KR20070122525A KR 20070122525 A KR20070122525 A KR 20070122525A KR 1020077025262 A KR1020077025262 A KR 1020077025262A KR 20077025262 A KR20077025262 A KR 20077025262A KR 20070122525 A KR20070122525 A KR 20070122525A
Authority
KR
South Korea
Prior art keywords
optical
detection
detector
disk
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020077025262A
Other languages
English (en)
Korean (ko)
Inventor
윌리암 베딩햄
피터 디. 루도와이즈
베리 더블유. 로볼레
Original Assignee
쓰리엠 이노베이티브 프로퍼티즈 컴파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 쓰리엠 이노베이티브 프로퍼티즈 컴파니 filed Critical 쓰리엠 이노베이티브 프로퍼티즈 컴파니
Publication of KR20070122525A publication Critical patent/KR20070122525A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406Fluorescence spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/024Modular construction

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
KR1020077025262A 2005-04-01 2006-03-24 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을갖는 멀티플렉스 형광 검출 장치 Ceased KR20070122525A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66746105P 2005-04-01 2005-04-01
US60/667,461 2005-04-01
US11/174,755 2005-07-05
US11/174,755 US7709249B2 (en) 2005-04-01 2005-07-05 Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020137010585A Division KR20130050391A (ko) 2005-04-01 2006-03-24 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을 갖는 멀티플렉스 형광 검출 장치

Publications (1)

Publication Number Publication Date
KR20070122525A true KR20070122525A (ko) 2007-12-31

Family

ID=36579427

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020077025262A Ceased KR20070122525A (ko) 2005-04-01 2006-03-24 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을갖는 멀티플렉스 형광 검출 장치
KR1020137010585A Ceased KR20130050391A (ko) 2005-04-01 2006-03-24 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을 갖는 멀티플렉스 형광 검출 장치

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020137010585A Ceased KR20130050391A (ko) 2005-04-01 2006-03-24 통상의 검출기에 다중 광학 모듈을 결합하는 섬유 다발을 갖는 멀티플렉스 형광 검출 장치

Country Status (11)

Country Link
US (1) US7709249B2 (enExample)
EP (1) EP1866631B1 (enExample)
JP (1) JP5021615B2 (enExample)
KR (2) KR20070122525A (enExample)
AT (1) ATE507473T1 (enExample)
AU (1) AU2006232930A1 (enExample)
BR (1) BRPI0609769B8 (enExample)
CA (1) CA2602252A1 (enExample)
DE (1) DE602006021554D1 (enExample)
MX (1) MX2007012158A (enExample)
WO (1) WO2006107627A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101302353B1 (ko) * 2012-02-29 2013-09-06 케이맥(주) 유전자 정량 검출 실시간 pcr 및 유전자 분석 dna 마이크로어레이를 복합적으로 수행할 수 있는 분자진단 자동분석기기
KR20230057234A (ko) * 2021-10-21 2023-04-28 주식회사 유니오텍 광섬유를 포함하는 광학모듈 및 이를 포함하는 광학 검사장치
KR20230085350A (ko) * 2021-12-07 2023-06-14 한국광기술원 1차원 광센서를 이용한 다중 웰 pcr 형광 측정 장치

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9493805B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensors with enhanced activity retention for detection of organic compounds
US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
US7663092B2 (en) 2005-02-01 2010-02-16 Purdue Research Foundation Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay
US20070023643A1 (en) 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US7709249B2 (en) 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7527763B2 (en) 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
JP2009504333A (ja) * 2005-08-15 2009-02-05 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 針生検イメージングシステム
US7522282B2 (en) 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
US7659968B2 (en) 2007-01-19 2010-02-09 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
US7787126B2 (en) 2007-03-26 2010-08-31 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
US9796998B2 (en) 2007-04-09 2017-10-24 Colorado State University Research Foundation Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations
CN101903761B (zh) 2007-12-19 2015-04-22 皇家飞利浦电子股份有限公司 检测系统和方法
US9121055B2 (en) * 2008-04-24 2015-09-01 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
US9017610B2 (en) * 2008-04-25 2015-04-28 Roche Diagnostics Hematology, Inc. Method of determining a complete blood count and a white blood cell differential count
US9602777B2 (en) * 2008-04-25 2017-03-21 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
US9017946B2 (en) 2008-06-23 2015-04-28 Canon U.S. Life Sciences, Inc. Systems and methods for monitoring the amplification of DNA
FR2939887B1 (fr) * 2008-12-11 2017-12-08 Silios Tech Dispositif de spectroscopie optique comportant une pluralite de sources d'emission
JP5279481B2 (ja) 2008-12-25 2013-09-04 株式会社日立ハイテクノロジーズ 核酸分析装置
US8455844B2 (en) * 2009-03-11 2013-06-04 Colorado State University Research Foundation System and method for time-division multiplexed optical sensing of biosensors
AU2010237532B2 (en) * 2009-04-15 2014-11-20 Biocartis Nv Optical detection system for monitoring rtPCR reaction
AU2010241731B2 (en) 2009-04-27 2015-08-06 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
US20110001963A1 (en) * 2009-07-02 2011-01-06 Durack Gary P System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system
EP3375891B1 (en) * 2009-09-10 2020-02-19 DiaSorin S.p.A. Methods and devices for compensation of spectral crosstalk in multiplex nucleic acid amplification
US8729502B1 (en) 2010-10-28 2014-05-20 The Research Foundation For The State University Of New York Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection
WO2012071471A2 (en) 2010-11-22 2012-05-31 Colorado State University Research Foundation Biosensing systems for measurement of lactose
KR20120080056A (ko) * 2011-01-06 2012-07-16 삼성전자주식회사 디스크 및 이를 이용한 검사장치의 보정방법
DE202011001569U1 (de) * 2011-01-14 2012-03-01 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur Messung von optischen Eigenschaften in Mikroplatten
US9111343B2 (en) 2011-01-18 2015-08-18 Roche Diagnostics Hematology, Inc. Microscope slide coordinate system registration
CN103403521B (zh) 2011-03-08 2016-08-10 拉瓦勒大学 流体向心装置
EP2697623B1 (en) 2011-04-15 2021-06-30 Roche Diagnostics Hematology, Inc. System and method for determining a mean cell volume for a blood sample
AU2012255151B2 (en) 2011-05-18 2015-09-03 Diasorin Italia S.P.A. Systems and methods for detecting the presence of a selected volume of material in a sample processing device
EP2709761B1 (en) 2011-05-18 2019-08-14 DiaSorin S.p.A. Systems and methods for volumetric metering on a sample processing device
USD672467S1 (en) 2011-05-18 2012-12-11 3M Innovative Properties Company Rotatable sample processing disk
KR101963721B1 (ko) 2011-05-18 2019-03-29 디아소린 에스.피.에이. 샘플 처리 장치 상의 밸빙을 위한 시스템 및 방법
US9499853B2 (en) 2011-08-02 2016-11-22 Colorado State University Research Foundation Biosensing system with extended lifetime via cofactor recycling
EP2761027B1 (en) * 2011-09-30 2017-10-25 Life Technologies Corporation Methods and systems for visualizing and evaluating data
EP4361608A3 (en) 2012-02-03 2024-07-24 California Institute of Technology Signal encoding and decoding in multiplexed biochemical assays
AU2013203281A1 (en) 2012-02-03 2013-08-22 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
WO2014000037A1 (en) 2012-06-26 2014-01-03 Axxin Pty Ltd Nucleic acid amplification and detection kit
EP3901243A1 (en) * 2012-08-03 2021-10-27 California Institute of Technology Multiplexing and quantification in pcr with reduced hardware and requirements
JP5987573B2 (ja) 2012-09-12 2016-09-07 セイコーエプソン株式会社 光学モジュール、電子機器、及び駆動方法
BR112015013166A2 (pt) 2012-12-05 2017-07-11 Genepoc Inc dispositivo de interrogação óptica
WO2014168734A1 (en) 2013-03-15 2014-10-16 Cedars-Sinai Medical Center Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof
JP5919218B2 (ja) * 2013-04-05 2016-05-18 株式会社日立ハイテクノロジーズ 核酸分析装置及び核酸分析方法
US10908073B2 (en) * 2014-08-28 2021-02-02 Single Technologies Ab High throughput biochemical screening
US10463290B2 (en) 2014-11-14 2019-11-05 Axxin Pty Ltd. Biological sample collection and storage assembly
EP3290909B1 (en) * 2015-05-01 2021-10-06 Universal Bio Research Co., Ltd. Parallel measurement device and parallel measurement method for multiple reactions
WO2017011862A1 (en) 2015-07-17 2017-01-26 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
WO2017173315A1 (en) 2016-04-01 2017-10-05 Black Light Surgical, Inc. Systems, devices, and methods for time-resolved fluorescent spectroscopy
CN106198480B (zh) * 2016-08-30 2018-09-14 广州蓝勃生物科技有限公司 一种自动干式荧光检测仪
US11709175B2 (en) 2017-09-27 2023-07-25 Axxin Pty Ltd Diagnostic test system and method utilizing a closure/sample dispensing mechanism to dispense a sample subvolume for testing
EP3704469A4 (en) 2017-10-31 2021-07-21 Alberta Biophotonics Inc. METHOD AND SYSTEM FOR OPTICAL MEASUREMENT
CN111758019B (zh) * 2018-01-23 2024-06-28 贝克顿·迪金森公司 用于动态光检测遮蔽的系统及其使用方法
US12454720B2 (en) 2018-04-17 2025-10-28 ChromaCode, Inc. Methods and systems for multiplex analysis
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
JP7197134B2 (ja) * 2019-03-12 2022-12-27 株式会社日立ハイテクサイエンス 蛍光光度計および観測方法
CN111551531B (zh) * 2020-05-19 2023-04-18 北京金诺美科技股份有限公司 一种荧光激发系统及实时荧光定量pcr仪
WO2022087438A1 (en) * 2020-10-23 2022-04-28 Quantum-Si Incorporated Systems and methods for sample process scaling
CN112683863A (zh) * 2020-12-11 2021-04-20 深圳砺剑防卫技术有限公司 一种多模荧光检测仪及其检测方法
US12461029B2 (en) * 2021-03-10 2025-11-04 Northeastern University Continuous flow air sampling and rapid pathogen detection system
KR102742889B1 (ko) * 2022-03-08 2024-12-16 주식회사 유진셀 검체 검사 장치 및 검체 검사 방법
CN120721701B (zh) * 2025-09-01 2025-11-14 长春理工大学 一种基于光纤传光的荧光检测系统及方法

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918793A (en) * 1970-05-02 1975-11-11 Leitz Ernst Gmbh Fluorescence illuminator for incident light microscope
DE2055944A1 (de) 1970-11-13 1972-05-18 Leitz Ernst Gmbh Fluoreszenzauflichtilluminator
DE2420545C3 (de) * 1974-04-27 1979-01-25 H. Maihak Ag, 2000 Hamburg Infrarotstrahleranordnung
GB1599452A (en) 1978-02-02 1981-10-07 Thorn Emi Ltd Infra-red heating device
JPS55156840A (en) * 1979-05-25 1980-12-06 Olympus Optical Co Ltd Specimen detector
JPS6120839A (ja) 1984-07-10 1986-01-29 Fuji Photo Film Co Ltd バクテリアカウンタ
US4726676A (en) * 1986-02-06 1988-02-23 General Signal Corporation Optical signal power measurement method and apparatus
US4927766A (en) * 1986-05-27 1990-05-22 The Boc Group, Inc. Gas constituent measurement and recording
US4909990A (en) * 1987-09-02 1990-03-20 Myron J. Block Immunoassay apparatus
GB8919700D0 (en) 1989-08-31 1989-10-11 Electricity Council Infra-red radiation emission arrangement
US7273749B1 (en) * 1990-06-04 2007-09-25 University Of Utah Research Foundation Container for carrying out and monitoring biological processes
US5296958A (en) * 1992-05-29 1994-03-22 Eastman Kodak Company Multiple wavelength laser beam scanning system
JPH0634546A (ja) * 1992-07-17 1994-02-08 Tosoh Corp 蛍光検出器
CA2100020C (en) * 1992-07-17 2001-09-11 Walter Blumenfeld Methods and apparatus for detecting bacterial growth by spectrophotometric sampling of a fiber-optic array
US5414600A (en) * 1993-07-30 1995-05-09 Cogent Light Technologies, Inc. Condensing and collecting optical system using an ellipsoidal reflector
ATE198511T1 (de) * 1994-04-29 2001-01-15 Perkin Elmer Corp Verfahren und vorrichtung zur echtzeiterfassung der produkte von nukleinsäureamplifikation
US5766889A (en) * 1994-06-08 1998-06-16 The Perkin-Elmer Corporation Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample
GB9418981D0 (en) * 1994-09-21 1994-11-09 Univ Glasgow Apparatus and method for carrying out analysis of samples
US6327031B1 (en) * 1998-09-18 2001-12-04 Burstein Technologies, Inc. Apparatus and semi-reflective optical system for carrying out analysis of samples
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5639668A (en) * 1995-09-14 1997-06-17 Boehringer Mannheim Corporation Optical apparatus for performing an immunoassay
US6342349B1 (en) * 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US5751874A (en) * 1996-09-13 1998-05-12 Nuvisions International, Inc. Coupling device for linking optical fiber connectors
DE19707226A1 (de) * 1997-02-24 1998-08-27 Bodenseewerk Perkin Elmer Co Lichtabtastvorrichtung
CN1249816A (zh) 1997-02-28 2000-04-05 伯斯坦恩实验室股份有限公司 盘片中的实验室
KR100345817B1 (ko) * 1997-03-25 2002-07-24 산요 덴키 가부시키가이샤 정보 재생 장치와 정보 기록 장치 및 기준 마크 검출 회로
JP2001516071A (ja) * 1997-09-05 2001-09-25 ライカ マイクロシステムス アクチエンゲゼルシャフト 顕微鏡、特に蛍光顕微鏡、特に立体蛍光顕微鏡
US6597450B1 (en) * 1997-09-15 2003-07-22 Becton, Dickinson And Company Automated Optical Reader for Nucleic Acid Assays
US6561428B2 (en) * 1997-10-17 2003-05-13 Hand Held Products, Inc. Imaging device having indicia-controlled image parsing mode
US5994150A (en) * 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
CA2318180A1 (en) * 1998-01-26 1999-07-29 Massachusetts Institute Of Technology Fluorescence imaging endoscope
US6210882B1 (en) * 1998-01-29 2001-04-03 Mayo Foundation For Medical Education And Reseach Rapid thermocycling for sample analysis
US6161946A (en) * 1998-11-09 2000-12-19 Bishop; Christopher B. Light reflector
US6232075B1 (en) * 1998-12-14 2001-05-15 Li-Cor, Inc. Heterogeneous assay for pyrophosphate detection
US6635470B1 (en) * 1999-01-08 2003-10-21 Applera Corporation Fiber array and methods for using and making same
JP3597729B2 (ja) * 1999-05-11 2004-12-08 日立ソフトウエアエンジニアリング株式会社 蛍光測光方法及び蛍光測光装置
US7410793B2 (en) * 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US7170597B1 (en) 1999-06-26 2007-01-30 Packard Instrument Company, Inc. Microplate reader
US7088650B1 (en) * 1999-08-23 2006-08-08 Worthington Mark O Methods and apparatus for optical disc data acquisition using physical synchronization markers
CN1311436A (zh) 2000-03-01 2001-09-05 上海和泰光电科技有限公司 旋转平台上的生物芯片荧光图象的读取
JP2001281587A (ja) * 2000-03-31 2001-10-10 Fuji Photo Optical Co Ltd 光走査装置用光源部の保持構造
US6795189B2 (en) * 2000-06-15 2004-09-21 Packard Instrument Company Universal microplate analyzer
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) * 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6563581B1 (en) * 2000-07-14 2003-05-13 Applera Corporation Scanning system and method for scanning a plurality of samples
FR2812306B1 (fr) * 2000-07-28 2005-01-14 Gabriel Festoc Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles
US6545758B1 (en) * 2000-08-17 2003-04-08 Perry Sandstrom Microarray detector and synthesizer
US6452879B1 (en) * 2000-09-29 2002-09-17 Fujitsu Limited Optical storage apparatus
WO2002029850A2 (en) * 2000-10-04 2002-04-11 Cogent Light Technologies, Inc. Temperature control for arc lamps
SE0004296D0 (sv) * 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US20020172980A1 (en) * 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
AU2002219979A1 (en) 2000-12-01 2002-06-11 Burstein Technologies, Inc. Apparatus and methods for separating components of particulate suspension
WO2002073605A2 (en) 2001-03-14 2002-09-19 Burstein Technologies, Inc. Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US20030054563A1 (en) * 2001-09-17 2003-03-20 Gyros Ab Detector arrangement for microfluidic devices
US6597832B2 (en) * 2001-12-07 2003-07-22 Yu-Feng Cheng Optical fiber selector
CN2522854Y (zh) 2001-12-24 2002-11-27 上海枫岭生物技术有限公司 实时荧光定量基因扩增仪光路系统
CN1262833C (zh) 2001-12-24 2006-07-05 上海枫岭生物技术有限公司 实时荧光定量基因扩增仪的光信号检测方法及其光路系统
US6889468B2 (en) 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
US20050023765A1 (en) * 2002-01-31 2005-02-03 Coombs James Howard Bio-safety features for optical analysis disc and disc system including same
US6767155B2 (en) * 2002-04-05 2004-07-27 Eastman Kodak Company High stability latch mechanism
JP4338529B2 (ja) * 2002-04-08 2009-10-07 ユロス・パテント・アクチボラゲット ホーミングプロセス
US6833536B2 (en) * 2002-05-22 2004-12-21 Applera Corporation Non-contact radiant heating and temperature sensing device for a chemical reaction chamber
AU2003243268A1 (en) 2002-05-17 2003-12-02 Applera Corporation Optical instrument including excitation source
EP1506390B1 (en) 2002-05-17 2011-12-14 Life Technologies Corporation Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
US20030219754A1 (en) * 2002-05-23 2003-11-27 Oleksy Jerome E. Fluorescence polarization detection of nucleic acids
AUPS267802A0 (en) 2002-05-30 2002-06-20 Bio-Molecular Holdings Pty Limited Improved dna amplification apparatus and method
JP4193421B2 (ja) * 2002-06-06 2008-12-10 ソニー株式会社 バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法
US7452507B2 (en) * 2002-08-02 2008-11-18 Sandia Corporation Portable apparatus for separating sample and detecting target analytes
EP2096341A1 (en) * 2002-12-04 2009-09-02 Spinx, Inc, Devices and methods for programmable microscale manipulation of fluids
US20050014249A1 (en) * 2003-02-21 2005-01-20 Norbert Staimer Chromatographic analysis on optical bio-discs and methods relating thereto
US20050032089A1 (en) 2003-03-05 2005-02-10 Phan Brigitte Chau Sample preparation for colorimetric and fluorescent assays as implemented on optical analysis discs
ES2384170T3 (es) 2003-04-04 2012-07-02 F. Hoffmann-La Roche Ag Sistema mejorado de PCR multicolor a tiempo real
US7148043B2 (en) * 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7238269B2 (en) * 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
US6879032B2 (en) * 2003-07-18 2005-04-12 Agilent Technologies, Inc. Folded flex circuit interconnect having a grid array interface
US7317415B2 (en) * 2003-08-08 2008-01-08 Affymetrix, Inc. System, method, and product for scanning of biological materials employing dual analog integrators
TWI238995B (en) * 2003-10-06 2005-09-01 Benq Corp Optical disk drive having disk mounting structure for preventing disk vibrating
US20050074784A1 (en) * 2003-10-07 2005-04-07 Tuan Vo-Dinh Integrated biochip with continuous sampling and processing (CSP) system
US7322254B2 (en) * 2003-12-12 2008-01-29 3M Innovative Properties Company Variable valve apparatus and methods
US20050130177A1 (en) * 2003-12-12 2005-06-16 3M Innovative Properties Company Variable valve apparatus and methods
US7295316B2 (en) * 2004-01-14 2007-11-13 Applera Corporation Fluorescent detector with automatic changing filters
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US7709249B2 (en) 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7527763B2 (en) * 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
US7754474B2 (en) * 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101302353B1 (ko) * 2012-02-29 2013-09-06 케이맥(주) 유전자 정량 검출 실시간 pcr 및 유전자 분석 dna 마이크로어레이를 복합적으로 수행할 수 있는 분자진단 자동분석기기
KR20230057234A (ko) * 2021-10-21 2023-04-28 주식회사 유니오텍 광섬유를 포함하는 광학모듈 및 이를 포함하는 광학 검사장치
KR20230085350A (ko) * 2021-12-07 2023-06-14 한국광기술원 1차원 광센서를 이용한 다중 웰 pcr 형광 측정 장치

Also Published As

Publication number Publication date
US7709249B2 (en) 2010-05-04
JP5021615B2 (ja) 2012-09-12
AU2006232930A1 (en) 2006-10-12
WO2006107627A1 (en) 2006-10-12
US20060223172A1 (en) 2006-10-05
CA2602252A1 (en) 2006-10-12
DE602006021554D1 (de) 2011-06-09
MX2007012158A (es) 2007-12-10
BRPI0609769B8 (pt) 2019-02-12
KR20130050391A (ko) 2013-05-15
EP1866631B1 (en) 2011-04-27
EP1866631A1 (en) 2007-12-19
ATE507473T1 (de) 2011-05-15
JP2008534966A (ja) 2008-08-28
BRPI0609769B1 (pt) 2018-02-06
BRPI0609769A2 (pt) 2011-10-18

Similar Documents

Publication Publication Date Title
EP1866631B1 (en) Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
KR101265362B1 (ko) 제거가능한 광학 모듈을 갖는 멀티플렉스 형광 검출 장치
EP1902306B1 (en) Detection device, detection system and method
CN101156059B (zh) 具有将多个光学模块连接到公共检测器的纤维束的多重荧光检测装置
EP2475788B1 (en) Compensation for spectral crosstalk in multiplex nucleic acid amplification
US20070009382A1 (en) Heating element for a rotating multiplex fluorescence detection device

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20071031

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20110323

Comment text: Request for Examination of Application

PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20120531

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20121226

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20120531

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20130326

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20121226

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20141023

Appeal identifier: 2013101002220

Request date: 20130326

A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20130425

J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20130326

Effective date: 20141023

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20141023

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 20130326

Decision date: 20141023

Appeal identifier: 2013101002220