MX2007012158A - Dispositivo de deteccion de fluorescencia de transmision multiple que tiene modulos opticos multiples de acoplamiento a un haz de fibras para un detector comun. - Google Patents

Dispositivo de deteccion de fluorescencia de transmision multiple que tiene modulos opticos multiples de acoplamiento a un haz de fibras para un detector comun.

Info

Publication number
MX2007012158A
MX2007012158A MX2007012158A MX2007012158A MX2007012158A MX 2007012158 A MX2007012158 A MX 2007012158A MX 2007012158 A MX2007012158 A MX 2007012158A MX 2007012158 A MX2007012158 A MX 2007012158A MX 2007012158 A MX2007012158 A MX 2007012158A
Authority
MX
Mexico
Prior art keywords
optical modules
detection device
species
multiple optical
fiber bundle
Prior art date
Application number
MX2007012158A
Other languages
English (en)
Inventor
William Bedingham
Peter D Ludowise
Barry W Robole
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of MX2007012158A publication Critical patent/MX2007012158A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/024—Modular construction

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

La presente invencion se refiere a tecnicas para la deteccion de especies objetivo multiples en la PCR (reaccion en cadena de la polimerasa) en tiempo real. Por ejemplo, se describe un sistema que incluye un dispositivo de adquisicion de datos y un dispositivo de deteccion acoplado al dispositivo de adquisicion de datos. El dispositivo de deteccion incluye un disco giratorio que tiene una pluralidad de camaras de proceso que tienen una pluralidad de especies que emiten luz fluorescente a diferentes longitudes de onda. El dispositivo incluye ademas una pluralidad de modulos opticos. Cada uno de los modulos opticos esta configurado opticamente para excitar las especies y para capturar la luz fluorescente emitida por las especies a diferentes longitudes de onda. Un haz de fibras opticas acoplado a la pluralidad de modulos opticos transporta la luz fluorescente desde los modulos opticos multiples hasta un solo detector.
MX2007012158A 2005-04-01 2006-03-24 Dispositivo de deteccion de fluorescencia de transmision multiple que tiene modulos opticos multiples de acoplamiento a un haz de fibras para un detector comun. MX2007012158A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66746105P 2005-04-01 2005-04-01
US11/174,755 US7709249B2 (en) 2005-04-01 2005-07-05 Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
PCT/US2006/010978 WO2006107627A1 (en) 2005-04-01 2006-03-24 Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector

Publications (1)

Publication Number Publication Date
MX2007012158A true MX2007012158A (es) 2007-12-10

Family

ID=36579427

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007012158A MX2007012158A (es) 2005-04-01 2006-03-24 Dispositivo de deteccion de fluorescencia de transmision multiple que tiene modulos opticos multiples de acoplamiento a un haz de fibras para un detector comun.

Country Status (11)

Country Link
US (1) US7709249B2 (es)
EP (1) EP1866631B1 (es)
JP (1) JP5021615B2 (es)
KR (2) KR20130050391A (es)
AT (1) ATE507473T1 (es)
AU (1) AU2006232930A1 (es)
BR (1) BRPI0609769B8 (es)
CA (1) CA2602252A1 (es)
DE (1) DE602006021554D1 (es)
MX (1) MX2007012158A (es)
WO (1) WO2006107627A1 (es)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9493805B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensors with enhanced activity retention for detection of organic compounds
US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
US20070023643A1 (en) 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
WO2006083917A2 (en) 2005-02-01 2006-08-10 Purdue Research Foundation Laser scanning interferometric surface metrology
US7709249B2 (en) 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US7527763B2 (en) * 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
AU2006279560A1 (en) * 2005-08-15 2007-02-22 Board Of Regents, The University Of Texas System Needle biopsy imaging system
US7659968B2 (en) 2007-01-19 2010-02-09 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
WO2008118934A1 (en) 2007-03-26 2008-10-02 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
US9796998B2 (en) 2007-04-09 2017-10-24 Colorado State University Research Foundation Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations
EP2225548B1 (en) 2007-12-19 2019-06-26 Koninklijke Philips N.V. Detection system and method
AU2009240461A1 (en) * 2008-04-24 2009-10-29 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
WO2012030313A1 (en) * 2008-04-25 2012-03-08 James Winkelman Method of determining a complete blood count and a white blood cell differential count
US9602777B2 (en) 2008-04-25 2017-03-21 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
US9017946B2 (en) * 2008-06-23 2015-04-28 Canon U.S. Life Sciences, Inc. Systems and methods for monitoring the amplification of DNA
FR2939887B1 (fr) * 2008-12-11 2017-12-08 Silios Tech Dispositif de spectroscopie optique comportant une pluralite de sources d'emission
JP5279481B2 (ja) 2008-12-25 2013-09-04 株式会社日立ハイテクノロジーズ 核酸分析装置
US8455844B2 (en) * 2009-03-11 2013-06-04 Colorado State University Research Foundation System and method for time-division multiplexed optical sensing of biosensors
EP2419743B1 (en) * 2009-04-15 2020-08-05 Biocartis NV OPTICAL DETECTION SYSTEM FOR MONITORING rtPCR REACTION
ES2903147T3 (es) 2009-04-27 2022-03-31 Roche Diagnostics Hematology Inc Sistemas y procedimientos para analizar líquidos corporales
US20110001963A1 (en) * 2009-07-02 2011-01-06 Durack Gary P System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system
ES2680495T3 (es) 2009-09-10 2018-09-07 Diasorin S.P.A. Compensación para interferencia espectral en la amplificación multiplex de ácidos nucleicos
US8729502B1 (en) 2010-10-28 2014-05-20 The Research Foundation For The State University Of New York Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection
US10024797B2 (en) 2010-11-22 2018-07-17 Colorado State University Research Foundation Biosensing systems for measurement of lactose
KR20120080056A (ko) * 2011-01-06 2012-07-16 삼성전자주식회사 디스크 및 이를 이용한 검사장치의 보정방법
DE202011001569U1 (de) * 2011-01-14 2012-03-01 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur Messung von optischen Eigenschaften in Mikroplatten
US9111343B2 (en) 2011-01-18 2015-08-18 Roche Diagnostics Hematology, Inc. Microscope slide coordinate system registration
PT3270141T (pt) 2011-03-08 2020-08-28 Univ Laval Dispositivo centrípeto fluídico
EP3904859B1 (en) * 2011-04-15 2023-08-30 Roche Diagnostics Hematology, Inc. System and method for determining a platelet volume for a blood sample, computer program and computer readable medium
USD672467S1 (en) 2011-05-18 2012-12-11 3M Innovative Properties Company Rotatable sample processing disk
EP2709761B1 (en) 2011-05-18 2019-08-14 DiaSorin S.p.A. Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device
BR112013027990B1 (pt) 2011-05-18 2020-11-03 Diasorin S.P.A. estrutura de válvulas em um dispositivo de processamento de amostras e método para funcionamento de válvulas em um dispositivo de processamento de amostras
WO2013019982A2 (en) 2011-08-02 2013-02-07 Colorado State University Research Foundation Biosensing system with extended lifetime via cofactor recycling
US10453557B2 (en) * 2011-09-30 2019-10-22 Life Technologies Corporation Methods and systems for visualizing and evaluating data
AU2013203281A1 (en) * 2012-02-03 2013-08-22 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
EP2809813B1 (en) 2012-02-03 2018-08-08 California Institute of Technology Signal encoding and decoding in multiplexed biochemical assays
KR101302353B1 (ko) * 2012-02-29 2013-09-06 케이맥(주) 유전자 정량 검출 실시간 ｐｃｒ 및 유전자 분석 ｄｎａ 마이크로어레이를 복합적으로 수행할 수 있는 분자진단 자동분석기기
EP2864503B1 (en) 2012-06-26 2019-10-09 Axxin Pty Ltd Nucleic acid amplification and detection kit
WO2014022827A1 (en) * 2012-08-03 2014-02-06 California Institute Of Technology Multiplexing and quantification in pcr with reduced hardware and requirements
JP5987573B2 (ja) * 2012-09-12 2016-09-07 セイコーエプソン株式会社 光学モジュール、電子機器、及び駆動方法
CN105008878B (zh) 2012-12-05 2017-09-19 吉恩波克公司 光学探询器件
WO2014168734A1 (en) * 2013-03-15 2014-10-16 Cedars-Sinai Medical Center Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof
JP5919218B2 (ja) * 2013-04-05 2016-05-18 株式会社日立ハイテクノロジーズ 核酸分析装置及び核酸分析方法
WO2016030464A1 (en) * 2014-08-28 2016-03-03 Single Technologies Ab High throughput biochemical screening
EP3218698B1 (en) 2014-11-14 2020-05-13 Axxin Pty Ltd Biological sample collection and storage assembly
WO2016178401A1 (ja) * 2015-05-01 2016-11-10 ユニバーサル・バイオ・リサーチ株式会社 多重反応並行測定装置およびその方法
AU2016295422B2 (en) 2015-07-17 2022-01-06 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
EP3436805A4 (en) 2016-04-01 2019-12-11 Black Light Surgical, Inc. SYSTEMS, DEVICES AND METHODS FOR TIME-RESOLUTION FLUORESCENCE SPECTROSCOPY
CN106198480B (zh) * 2016-08-30 2018-09-14 广州蓝勃生物科技有限公司 一种自动干式荧光检测仪
WO2019060950A1 (en) 2017-09-27 2019-04-04 Axxin Pty Ltd SYSTEM AND METHOD FOR DIAGNOSTIC TESTING
EP3704469A4 (en) 2017-10-31 2021-07-21 Alberta Biophotonics Inc. METHOD AND SYSTEM FOR OPTICAL MEASUREMENT
JP7197134B2 (ja) * 2019-03-12 2022-12-27 株式会社日立ハイテクサイエンス 蛍光光度計および観測方法
CN111551531B (zh) * 2020-05-19 2023-04-18 北京金诺美科技股份有限公司 一种荧光激发系统及实时荧光定量pcr仪
CN112683863A (zh) * 2020-12-11 2021-04-20 深圳砺剑防卫技术有限公司 一种多模荧光检测仪及其检测方法

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055944A1 (de) 1970-11-13 1972-05-18 Leitz Ernst Gmbh Fluoreszenzauflichtilluminator
US3918793A (en) 1970-05-02 1975-11-11 Leitz Ernst Gmbh Fluorescence illuminator for incident light microscope
DE2420545C3 (de) 1974-04-27 1979-01-25 H. Maihak Ag, 2000 Hamburg Infrarotstrahleranordnung
GB1599452A (en) 1978-02-02 1981-10-07 Thorn Emi Ltd Infra-red heating device
JPS55156840A (en) 1979-05-25 1980-12-06 Olympus Optical Co Ltd Specimen detector
JPS6120839A (ja) 1984-07-10 1986-01-29 Fuji Photo Film Co Ltd バクテリアカウンタ
US4726676A (en) 1986-02-06 1988-02-23 General Signal Corporation Optical signal power measurement method and apparatus
US4927766A (en) 1986-05-27 1990-05-22 The Boc Group, Inc. Gas constituent measurement and recording
US4909990A (en) 1987-09-02 1990-03-20 Myron J. Block Immunoassay apparatus
GB8919700D0 (en) 1989-08-31 1989-10-11 Electricity Council Infra-red radiation emission arrangement
US7273749B1 (en) 1990-06-04 2007-09-25 University Of Utah Research Foundation Container for carrying out and monitoring biological processes
US5296958A (en) 1992-05-29 1994-03-22 Eastman Kodak Company Multiple wavelength laser beam scanning system
JPH0634546A (ja) 1992-07-17 1994-02-08 Tosoh Corp 蛍光検出器
CA2100020C (en) 1992-07-17 2001-09-11 Walter Blumenfeld Methods and apparatus for detecting bacterial growth by spectrophotometric sampling of a fiber-optic array
US5414600A (en) 1993-07-30 1995-05-09 Cogent Light Technologies, Inc. Condensing and collecting optical system using an ellipsoidal reflector
AU698953B2 (en) 1994-04-29 1998-11-12 Applied Biosystems, Llc System for real time detection of nucleic acid amplification products
US5766889A (en) 1994-06-08 1998-06-16 The Perkin-Elmer Corporation Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample
GB9418981D0 (en) 1994-09-21 1994-11-09 Univ Glasgow Apparatus and method for carrying out analysis of samples
US6327031B1 (en) 1998-09-18 2001-12-04 Burstein Technologies, Inc. Apparatus and semi-reflective optical system for carrying out analysis of samples
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5639668A (en) 1995-09-14 1997-06-17 Boehringer Mannheim Corporation Optical apparatus for performing an immunoassay
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US5751874A (en) 1996-09-13 1998-05-12 Nuvisions International, Inc. Coupling device for linking optical fiber connectors
DE19707226A1 (de) * 1997-02-24 1998-08-27 Bodenseewerk Perkin Elmer Co Lichtabtastvorrichtung
EA002403B1 (ru) 1997-02-28 2002-04-25 Бурштейн Текнолоджис, Инк. Лаборатория на диске
EP0969452A4 (en) 1997-03-25 2000-12-27 Sanyo Electric Co INFORMATION REPRODUCING AND RECORDING DEVICE AND REFERENCE MARK DETECTION CIRCUIT
US6563113B1 (en) 1997-09-05 2003-05-13 Leica Microsystems (Schweiz) Ag Microscope, especially a fluorescence microscope, particularly a stereo fluorescence microscope
US6597450B1 (en) 1997-09-15 2003-07-22 Becton, Dickinson And Company Automated Optical Reader for Nucleic Acid Assays
US6561428B2 (en) 1997-10-17 2003-05-13 Hand Held Products, Inc. Imaging device having indicia-controlled image parsing mode
US5994150A (en) 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
ATE391451T1 (de) 1998-01-26 2008-04-15 Massachusetts Inst Technology Endoskop zur erfassung von fluoreszenzbilder
US6210882B1 (en) 1998-01-29 2001-04-03 Mayo Foundation For Medical Education And Reseach Rapid thermocycling for sample analysis
US6161946A (en) 1998-11-09 2000-12-19 Bishop; Christopher B. Light reflector
ATE319857T1 (de) 1998-12-14 2006-03-15 Li Cor Inc Kit und methode zur nukleinsäuresequenzierung einzelner moleküle durch polymerase synthese
WO2000040334A1 (en) * 1999-01-08 2000-07-13 Pe Corporation (Ny) Fiber array for contacting chemical species and methods for using and making same
JP3597729B2 (ja) * 1999-05-11 2004-12-08 日立ソフトウエアエンジニアリング株式会社 蛍光測光方法及び蛍光測光装置
US7410793B2 (en) 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
EP1190232A1 (en) 1999-06-26 2002-03-27 Packard Instrument Company, Inc. Microplate reader
US7088650B1 (en) 1999-08-23 2006-08-08 Worthington Mark O Methods and apparatus for optical disc data acquisition using physical synchronization markers
CN1311436A (zh) 2000-03-01 2001-09-05 上海和泰光电科技有限公司 旋转平台上的生物芯片荧光图象的读取
JP2001281587A (ja) 2000-03-31 2001-10-10 Fuji Photo Optical Co Ltd 光走査装置用光源部の保持構造
US6795189B2 (en) 2000-06-15 2004-09-21 Packard Instrument Company Universal microplate analyzer
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6563581B1 (en) 2000-07-14 2003-05-13 Applera Corporation Scanning system and method for scanning a plurality of samples
FR2812306B1 (fr) 2000-07-28 2005-01-14 Gabriel Festoc Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles
US6545758B1 (en) 2000-08-17 2003-04-08 Perry Sandstrom Microarray detector and synthesizer
US6452879B1 (en) 2000-09-29 2002-09-17 Fujitsu Limited Optical storage apparatus
WO2002029850A2 (en) 2000-10-04 2002-04-11 Cogent Light Technologies, Inc. Temperature control for arc lamps
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US20020172980A1 (en) 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
US20020076354A1 (en) 2000-12-01 2002-06-20 Cohen David Samuel Apparatus and methods for separating components of particulate suspension
WO2002073605A2 (en) 2001-03-14 2002-09-19 Burstein Technologies, Inc. Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US20030054563A1 (en) 2001-09-17 2003-03-20 Gyros Ab Detector arrangement for microfluidic devices
US6597832B2 (en) 2001-12-07 2003-07-22 Yu-Feng Cheng Optical fiber selector
CN1262833C (zh) 2001-12-24 2006-07-05 上海枫岭生物技术有限公司 实时荧光定量基因扩增仪的光信号检测方法及其光路系统
CN2522854Y (zh) 2001-12-24 2002-11-27 上海枫岭生物技术有限公司 实时荧光定量基因扩增仪光路系统
US6889468B2 (en) 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
WO2003065355A2 (en) 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safety features for optical analysis disc and disc system including same
US6767155B2 (en) 2002-04-05 2004-07-27 Eastman Kodak Company High stability latch mechanism
AU2003222544A1 (en) 2002-04-08 2003-10-27 Gyros Ab Homing process
US6833536B2 (en) 2002-05-22 2004-12-21 Applera Corporation Non-contact radiant heating and temperature sensing device for a chemical reaction chamber
EP2674745B1 (en) 2002-05-17 2016-04-13 Life Technologies Corporation Instrument for detecting and measuring fluorescence
JP2005526253A (ja) 2002-05-17 2005-09-02 アプレラ コーポレイション 励起波長による複数の蛍光シグナルを分化するための装置および方法
US20030219754A1 (en) 2002-05-23 2003-11-27 Oleksy Jerome E. Fluorescence polarization detection of nucleic acids
AUPS267802A0 (en) 2002-05-30 2002-06-20 Bio-Molecular Holdings Pty Limited Improved dna amplification apparatus and method
JP4193421B2 (ja) 2002-06-06 2008-12-10 ソニー株式会社 バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法
US7452507B2 (en) 2002-08-02 2008-11-18 Sandia Corporation Portable apparatus for separating sample and detecting target analytes
WO2004050242A2 (en) 2002-12-04 2004-06-17 Spinx, Inc. Devices and methods for programmable microscale manipulation of fluids
US20050014249A1 (en) 2003-02-21 2005-01-20 Norbert Staimer Chromatographic analysis on optical bio-discs and methods relating thereto
US20050032089A1 (en) 2003-03-05 2005-02-10 Phan Brigitte Chau Sample preparation for colorimetric and fluorescent assays as implemented on optical analysis discs
EP2284278A1 (en) 2003-04-04 2011-02-16 Roche Diagnostics GmbH Improved system for multi color real time PCR
US7148043B2 (en) 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7238269B2 (en) 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
US6879032B2 (en) 2003-07-18 2005-04-12 Agilent Technologies, Inc. Folded flex circuit interconnect having a grid array interface
US7317415B2 (en) 2003-08-08 2008-01-08 Affymetrix, Inc. System, method, and product for scanning of biological materials employing dual analog integrators
TWI238995B (en) * 2003-10-06 2005-09-01 Benq Corp Optical disk drive having disk mounting structure for preventing disk vibrating
US20050074784A1 (en) 2003-10-07 2005-04-07 Tuan Vo-Dinh Integrated biochip with continuous sampling and processing (CSP) system
US7322254B2 (en) 2003-12-12 2008-01-29 3M Innovative Properties Company Variable valve apparatus and methods
US20050130177A1 (en) 2003-12-12 2005-06-16 3M Innovative Properties Company Variable valve apparatus and methods
US7295316B2 (en) 2004-01-14 2007-11-13 Applera Corporation Fluorescent detector with automatic changing filters
US7709249B2 (en) 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US20070009382A1 (en) 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
US7527763B2 (en) 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods

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JP2008534966A (ja) 2008-08-28
KR20130050391A (ko) 2013-05-15
WO2006107627A1 (en) 2006-10-12
DE602006021554D1 (de) 2011-06-09
CA2602252A1 (en) 2006-10-12
BRPI0609769B1 (pt) 2018-02-06
EP1866631B1 (en) 2011-04-27
BRPI0609769A2 (pt) 2011-10-18
KR20070122525A (ko) 2007-12-31
JP5021615B2 (ja) 2012-09-12
AU2006232930A1 (en) 2006-10-12
ATE507473T1 (de) 2011-05-15
EP1866631A1 (en) 2007-12-19
US20060223172A1 (en) 2006-10-05
US7709249B2 (en) 2010-05-04
BRPI0609769B8 (pt) 2019-02-12

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