KR20070091040A - 5-ｈｔ7 수용체 안타고니스트 - Google Patents
5-ｈｔ7 수용체 안타고니스트 Download PDFInfo
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- KR20070091040A KR20070091040A KR1020077017187A KR20077017187A KR20070091040A KR 20070091040 A KR20070091040 A KR 20070091040A KR 1020077017187 A KR1020077017187 A KR 1020077017187A KR 20077017187 A KR20077017187 A KR 20077017187A KR 20070091040 A KR20070091040 A KR 20070091040A
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Classifications
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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Landscapes
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| EP04380279A EP1676844A1 (en) | 2004-12-28 | 2004-12-28 | 5-HT7 receptor antagonists |
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| US11/048,992 | 2005-02-02 |
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| KR20070091040A true KR20070091040A (ko) | 2007-09-06 |
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| UA91341C2 (ru) | 2004-07-15 | 2010-07-26 | Амр Текнолоджи, Інк. | Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина |
| CA2706070A1 (en) * | 2006-11-21 | 2008-05-29 | University Of Tennessee Research Foundation | Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy |
| BRPI0811446A2 (pt) * | 2007-05-11 | 2014-10-29 | Lilly Co Eli | " 2-[4-(pirazol-4-ilalquil)piperazin-1-il]-3-fenil pirazinas e piridinas e 3-[4-(pirazol-4-ilalquil)piperazin-1-il]-2-fenil piridinas como antagonistas de receptor 5-ht7" |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| JP5683489B2 (ja) * | 2009-01-12 | 2015-03-11 | アレイ バイオファーマ、インコーポレイテッド | ピペリジン含有化合物およびその用途 |
| ES2446971T3 (es) | 2009-05-12 | 2014-03-11 | Albany Molecular Research, Inc. | Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso |
| JP5739415B2 (ja) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用 |
| CN102595902B (zh) * | 2009-05-12 | 2015-04-29 | 阿尔巴尼分子研究公司 | 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途 |
| GB201209587D0 (en) | 2012-05-30 | 2012-07-11 | Takeda Pharmaceutical | Therapeutic compounds |
| JP6401254B2 (ja) * | 2013-06-21 | 2018-10-10 | 武田薬品工業株式会社 | プロキネシチン受容体のモジュレータとしての１−スルホニルピペリジン誘導体 |
| GB201420095D0 (en) * | 2014-11-12 | 2014-12-24 | Takeda Pharmaceutical | New use |
| US11505529B2 (en) * | 2017-03-03 | 2022-11-22 | National Taiwan University | 8-phenyl-isoquinolines and pharmaceutical composition thereof used in the treatment of irritable bowel syndrome |
| US10357493B2 (en) | 2017-03-10 | 2019-07-23 | Selenity Therapeutics (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
| CN114727974A (zh) | 2019-07-30 | 2022-07-08 | 艾科尼佐治疗股份有限公司 | Hdac6抑制剂及其用途 |
| CN112083107B (zh) * | 2020-09-28 | 2022-07-05 | 中国计量科学研究院 | 检测蜂蜜基质中磺胺类药物葡萄糖醛酸结合物的方法 |
| WO2022169985A1 (en) | 2021-02-03 | 2022-08-11 | Eikonizo Therapeutics, Inc. | Hdac6 inhibitors and uses thereof |
| AU2023250964A1 (en) | 2022-04-08 | 2024-11-07 | Eikonizo Therapeutics, Inc. | Oxadiazole hdac6 inhibitors and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ193654A (en) | 1979-05-16 | 1984-08-24 | Wuelfing Johann A | Naphthalene sulphonamido-alkyl-piperidines,pyrrolidines or piperazines and pharmaceutical compositions |
| EP0076072B1 (en) | 1981-09-24 | 1987-05-13 | BEECHAM - WUELFING GmbH & Co. KG | Sulphonamides |
| JP2000504677A (ja) | 1996-02-09 | 2000-04-18 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５ｈｔ７レセプター・アンタゴニスト用のスルホンアミド誘導体 |
| GB9612884D0 (en) | 1996-06-20 | 1996-08-21 | Smithkline Beecham Plc | Novel compounds |
| EP0912550A1 (en) * | 1996-06-25 | 1999-05-06 | Smithkline Beecham Plc | Sulfonamide derivatives as 5ht7 receptor antagonists |
| WO1999024022A2 (en) | 1997-11-10 | 1999-05-20 | F. Hoffmann-La Roche Ag | Isoquinoline derivatives for treating disorders associated with 5ht7 receptors |
| WO2000000472A1 (en) * | 1998-06-30 | 2000-01-06 | Du Pont Pharmaceuticals Company | 5-ht7 receptor antagonists |
| GB0128885D0 (en) | 2001-12-03 | 2002-01-23 | Merck Sharp & Dohme | Therapeutic agents |
-
2004
- 2004-12-28 EP EP04380279A patent/EP1676844A1/en not_active Withdrawn
-
2005
- 2005-02-02 US US11/048,992 patent/US7345057B2/en not_active Expired - Fee Related
- 2005-12-27 WO PCT/EP2005/014046 patent/WO2006069776A1/en not_active Ceased
- 2005-12-27 MX MX2007007894A patent/MX2007007894A/es not_active Application Discontinuation
- 2005-12-27 JP JP2007548747A patent/JP2008525513A/ja active Pending
- 2005-12-27 AU AU2005321463A patent/AU2005321463A1/en not_active Abandoned
- 2005-12-27 RU RU2007128926/04A patent/RU2007128926A/ru not_active Application Discontinuation
- 2005-12-27 EP EP05849072A patent/EP1831195B1/en not_active Expired - Lifetime
- 2005-12-27 KR KR1020077017187A patent/KR20070091040A/ko not_active Withdrawn
- 2005-12-27 CA CA002590666A patent/CA2590666A1/en not_active Abandoned
- 2005-12-27 CN CNA2005800452243A patent/CN101090898A/zh active Pending
- 2005-12-27 BR BRPI0519792-9A patent/BRPI0519792A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005321463A1 (en) | 2006-07-06 |
| JP2008525513A (ja) | 2008-07-17 |
| WO2006069776A1 (en) | 2006-07-06 |
| EP1676844A1 (en) | 2006-07-05 |
| RU2007128926A (ru) | 2009-02-10 |
| MX2007007894A (es) | 2007-10-03 |
| BRPI0519792A2 (pt) | 2009-03-17 |
| EP1831195A1 (en) | 2007-09-12 |
| US7345057B2 (en) | 2008-03-18 |
| EP1831195B1 (en) | 2012-12-19 |
| CN101090898A (zh) | 2007-12-19 |
| US20060142332A1 (en) | 2006-06-29 |
| CA2590666A1 (en) | 2006-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20070725 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |