HK1219722A1 - -磺酰基派啶衍生物作為前動力蛋白受體的調節劑 - Google Patents

-磺酰基派啶衍生物作為前動力蛋白受體的調節劑

Info

Publication number
HK1219722A1
HK1219722A1 HK16107004.1A HK16107004A HK1219722A1 HK 1219722 A1 HK1219722 A1 HK 1219722A1 HK 16107004 A HK16107004 A HK 16107004A HK 1219722 A1 HK1219722 A1 HK 1219722A1
Authority
HK
Hong Kong
Prior art keywords
modulators
piperidine derivatives
prokineticin receptors
sulfonyl
sulfonyl piperidine
Prior art date
Application number
HK16107004.1A
Other languages
English (en)
Inventor
Martin Teall
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201311169A external-priority patent/GB201311169D0/en
Priority claimed from GB201314397A external-priority patent/GB201314397D0/en
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of HK1219722A1 publication Critical patent/HK1219722A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16107004.1A 2013-06-21 2016-06-17 -磺酰基派啶衍生物作為前動力蛋白受體的調節劑 HK1219722A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201311169A GB201311169D0 (en) 2013-06-21 2013-06-21 Therapeutic compounds
GB201314397A GB201314397D0 (en) 2013-08-09 2013-08-09 Therapeutic Compounds
PCT/GB2014/051900 WO2014202999A1 (en) 2013-06-21 2014-06-20 1-sulfonyl piperidine derivatives as modulators of prokineticin receptors

Publications (1)

Publication Number Publication Date
HK1219722A1 true HK1219722A1 (zh) 2017-04-13

Family

ID=50982934

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107004.1A HK1219722A1 (zh) 2013-06-21 2016-06-17 -磺酰基派啶衍生物作為前動力蛋白受體的調節劑

Country Status (9)

Country Link
US (2) US10208016B2 (zh)
EP (1) EP3010900B1 (zh)
JP (1) JP6401254B2 (zh)
CN (1) CN105324372B (zh)
AU (1) AU2014282977B2 (zh)
CA (1) CA2914263C (zh)
EA (1) EA029430B1 (zh)
HK (1) HK1219722A1 (zh)
WO (1) WO2014202999A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201420095D0 (en) * 2014-11-12 2014-12-24 Takeda Pharmaceutical New use

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006098A1 (en) 1994-08-24 1996-02-29 Astra Aktiebolag Spiro-azabicyclic compounds useful in therapy
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9600683D0 (sv) 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
AR013184A1 (es) 1997-07-18 2000-12-13 Astrazeneca Ab Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
SE9702799D0 (sv) 1997-07-25 1997-07-25 Astra Ab New compounds
SE9900100D0 (sv) 1999-01-15 1999-01-15 Astra Ab New compounds
SE9903760D0 (sv) 1999-10-18 1999-10-18 Astra Ab New compounds
SE9904176D0 (sv) 1999-11-18 1999-11-18 Astra Ab New use
SE0000540D0 (sv) 2000-02-18 2000-02-18 Astrazeneca Ab New compounds
SE0002729D0 (sv) 2000-07-20 2000-07-20 Astrazeneca Ab Novel compound form
NZ539828A (en) 2001-05-18 2007-01-26 Astrazeneca Ab 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
MXPA03010996A (es) 2001-06-01 2004-02-27 Aztrazeneca Ab Nuevo ligando para receptores nicotinicos de acetilcolina utiles en terapia.
EP1676844A1 (en) * 2004-12-28 2006-07-05 Laboratorios Del Dr. Esteve, S.A. 5-HT7 receptor antagonists
MXPA04010193A (es) 2002-04-18 2005-02-03 Astrazeneca Ab Compuesto de tienilo.
JP4511195B2 (ja) 2002-04-18 2010-07-28 アストラゼネカ・アクチエボラーグ フリル化合物
ES2326638T3 (es) 2002-04-18 2009-10-16 Astrazeneca Ab Compuestos heterociclicos.
SE0202465D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
SE0202430D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202598D0 (sv) 2002-09-02 2002-09-02 Astrazeneca Ab Alpha-7 Nicotinic receptor agonists and statins in combination
JP2006506451A (ja) * 2002-10-11 2006-02-23 アストラゼネカ アクチボラグ 1,4−ジ置換ピペリジン誘導体および11−βHSD1阻害薬としてのそれらの使用
PL1699455T3 (pl) * 2003-12-15 2013-10-31 Merck Sharp & Dohme Heterocykliczne inhibitory proteaz aspartylowych
BRPI0515500A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados piridazina para inibição de estearoil-coa-desaturase
JP2009518409A (ja) 2005-12-06 2009-05-07 メルク エンド カムパニー インコーポレーテッド モルホリンカルボキサミドプロキネチシン受容体アンタゴニスト
EP1976528A2 (en) 2005-12-29 2008-10-08 Janssen Pharmaceutica, N.V. Prokineticin 2 receptor antagonists
WO2010077976A2 (en) * 2008-12-17 2010-07-08 The Regents Of The University Of California Prokineticin receptor antagonists and uses thereof
EP2375899B1 (en) 2009-01-12 2015-02-25 Array Biopharma Inc. Piperidine-containing compounds and use thereof in the treatment of diabetes
GB201209587D0 (en) * 2012-05-30 2012-07-11 Takeda Pharmaceutical Therapeutic compounds
JP6343541B2 (ja) 2014-10-09 2018-06-13 株式会社ケーヒン・サーマル・テクノロジー エバポレータおよびこれを用いた車両用空調装置
GB201420095D0 (en) * 2014-11-12 2014-12-24 Takeda Pharmaceutical New use

Also Published As

Publication number Publication date
CA2914263C (en) 2021-05-18
US10308635B2 (en) 2019-06-04
JP6401254B2 (ja) 2018-10-10
CN105324372A (zh) 2016-02-10
US20180251445A1 (en) 2018-09-06
EP3010900A1 (en) 2016-04-27
AU2014282977B2 (en) 2018-06-14
US10208016B2 (en) 2019-02-19
CN105324372B (zh) 2018-03-06
US20160122317A1 (en) 2016-05-05
EP3010900B1 (en) 2018-01-03
CA2914263A1 (en) 2014-12-24
EA201600032A1 (ru) 2016-08-31
WO2014202999A1 (en) 2014-12-24
JP2016522244A (ja) 2016-07-28
AU2014282977A1 (en) 2015-12-24
BR112015031827A2 (pt) 2017-07-25
EA029430B1 (ru) 2018-03-30

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