KR20070046390A - 구제역 바이러스 3ab 비구조단백질과 이에 특이적으로반응하는 단일클론 항체 및 이들의 조합을 이용한 구제역바이러스의 비구조단백질 항체 검사 또는 구제역의 진단방법 - Google Patents
구제역 바이러스 3ab 비구조단백질과 이에 특이적으로반응하는 단일클론 항체 및 이들의 조합을 이용한 구제역바이러스의 비구조단백질 항체 검사 또는 구제역의 진단방법 Download PDFInfo
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- KR20070046390A KR20070046390A KR1020050103057A KR20050103057A KR20070046390A KR 20070046390 A KR20070046390 A KR 20070046390A KR 1020050103057 A KR1020050103057 A KR 1020050103057A KR 20050103057 A KR20050103057 A KR 20050103057A KR 20070046390 A KR20070046390 A KR 20070046390A
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Abstract
Description
Claims (6)
- 기탁번호 KCTC 10848BP인 하이브리도마 세포주에 의해서 생산되고, 구제역 바이러스의 서열번호 2와 3으로 표시된 에피토프 또는 실질적으로 동일한 에피토프와 특이적으로 반응하는 단일클론 항체.
- 구제역 바이러스의 단백질에서 서열번호 2와 서열번호 3으로 표시된 에피토프 또는 실질적으로 동일한 에피토프가 포함된 항원을 특이적으로 인식하는 단일클론 항체를 사용하여 구제역 바이러스의 비구조단백질 항체 검사 또는 구제역의 진단 방법.
- 제 2 항에 있어서,상기 항원은 구제역 바이러스 분리주(O/SKR/2002) 유전자(AY312589)의 3AB유전자 또는 3B 유전자의 염기서열에서 발현된 펩타이드 및 재조합 펩타이드 또는 이의 일부 펩타이드인 것을 특징으로 하는 구제역 바이러스의 비구조단백질 항체 검사 또는 구제역의 진단 방법.
- 제 2 항에 있어서,상기 단일클론 항체는 기탁번호 KCTC 10848BP인 하이브리도마 세포주에 의해서 생산되는 단일클론 항체인 것을 특징으로 하는 구제역 바이러스의 비구조단백질 항체 검사 또는 구제역의 진단 방법.
- 구제역 바이러스의 단백질에서 서열번호 2와 서열번호 3으로 표시된 에피토프이거나 실질적으로 동일한 에피토프가 포함된 항원 또는 상기 항원에 특이적으로 반응하는 단일클론 항체가 포함되어 이루어지는 구제역 진단 시약.
- 피검체로부터 채취한 생물학적 시료와 구제역 바이러스의 단백질에서 서열번호 2와 서열번호 3으로 표시된 에피토프이거나 실질적으로 동일한 에피토프가 포함된 항원 또는 상기 항원에 특이적으로 반응하는 단일클론 항체를 반응시켜 항원-항체 반응을 검출하는 구제역 진단 키트.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020050103057A KR100817264B1 (ko) | 2005-10-31 | 2005-10-31 | 구제역 바이러스 3ab 비구조단백질과 이에 특이적으로반응하는 단일클론 항체 및 이들의 조합을 이용한 구제역바이러스의 비구조단백질 항체 검사 또는 구제역의 진단방법 |
Applications Claiming Priority (1)
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KR101412038B1 (ko) * | 2012-07-27 | 2014-07-01 | 대한민국 | C형 구제역 바이러스 유전자재조합 단백질 항원과 단클론항체를 이용한 c형 구제역 진단방법 |
KR101873204B1 (ko) * | 2016-12-12 | 2018-07-12 | 대한민국 | 구제역 바이러스 입자 판별 방법 |
KR20200121426A (ko) * | 2019-04-15 | 2020-10-26 | 주식회사 바이오노트 | 구제역 바이러스 o형에 면역 반응성을 나타내는 항체를 이용한 구제역 백신 접종으로 생성된 항체를 검출하는 방법 |
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US6048538A (en) * | 1997-10-03 | 2000-04-11 | United Biomedical, Inc. | Peptides derived from the non-structural proteins of foot and mouth disease virus as diagnostic reagents |
KR100430934B1 (ko) * | 2001-12-21 | 2004-05-14 | 대한민국 | 곤충세포 발현 재조합 3abc 비구조단백질 항원 및 단클론항체를 이용한 구제역 진단방법 |
KR100449906B1 (ko) * | 2001-12-21 | 2004-09-22 | 대한민국 | 재조합 구제역 2c 비구조단백질 항원 및 단클론항체를이용한 구제역 진단방법 |
KR100536848B1 (ko) * | 2004-02-19 | 2005-12-19 | 대한민국 | 구제역 바이러스의 2c 및 3b 비구조단백질에 대한펩타이드를 포함하는 구제역 진단용 키트 |
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KR101412038B1 (ko) * | 2012-07-27 | 2014-07-01 | 대한민국 | C형 구제역 바이러스 유전자재조합 단백질 항원과 단클론항체를 이용한 c형 구제역 진단방법 |
KR101873204B1 (ko) * | 2016-12-12 | 2018-07-12 | 대한민국 | 구제역 바이러스 입자 판별 방법 |
KR20200121426A (ko) * | 2019-04-15 | 2020-10-26 | 주식회사 바이오노트 | 구제역 바이러스 o형에 면역 반응성을 나타내는 항체를 이용한 구제역 백신 접종으로 생성된 항체를 검출하는 방법 |
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