KR20050116503A - Raw herbal extracts composition and cataplasa - Google Patents

Abstract

In the present invention, a pharmaceutical composition layer is formed to form a film with a patch composition of hot water extracted by adding water as a solvent to a cold herb, creation, raw sulfur, and Angelica as an herbal ingredient having an appropriate composition ratio, and an adhesive substance using the same as an active ingredient. It is related to the healthy poultice paste, which is formed by adhesive coating on the functional outer skin which is mixed and made to produce micropores. It has no side effects such as skin allergy with the main ingredient of herbal medicine, and it is applied or applied to the bruise of the waist, joint, neck, etc. to the affected area such as muscle pain. When anti-inflammatory pain and cartilage protection by the complex synergistic effect of the functional, such as the pharmacological effect of the herbal medicine derived from natural products and the therapeutic effect of functional substances that are very beneficial to the human body, it is effective in alleviating the pain and treatment of neuralgia or myalgia, and preventing arthritis. Implement

Description

Patch ingredient composition for herbal treatment containing herbal extracts and healthy poultice paste using the same {Raw herbal extracts composition and cataplasa}

The present invention relates to a patch composition for a poultice containing a herbal extract and a healthy poultice paste using the same, more specifically, a patch composition of hot water extracted by adding water as a solvent to a cold herb, creation, fresh sulfur, and Angelica as a herbal composition of an appropriate composition ratio It is related to healthy poultice pars, which is formed by forming a pharmaceutical composition layer to form a film with an adhesive substance as an active ingredient and adhering and applying a functional substance to a paste-supported outer skin. It has no side effects such as allergies, and when applied or applied to affected areas such as waist, joint, neck, etc. Neuralgia due to anti-inflammatory analgesic effect by synergistic synergistic effect of functional substance such as pharmacological effect by natural herbal medicine and therapeutic effect of functional substance very beneficial to human body Pain relief and treatment and prevention Implement a number of effects.

       It is a conventional medicine containing painkillers, anti-inflammatory drugs, and arthritis drugs for the purpose of alleviating and treating pain such as muscle pain, bruises, back pain, joint pain, neuralgia, arthritis, and rheumatism of the lower back, joint, neck, etc. There are a wide variety of different types of parenteral external preparations, including parenteral transdermal agents, which are classified into pars, ointments, gels, aerosols, lotions, water pastes, and the like.

Ointments, gels, aerosols, and lotions of the parenteral treatments described above are less durable than the products to which they are attached, are easily removed from sweat or water, and the active ingredients are blown away into the air, causing frequent application. I prefer Pas.

Among the above-mentioned parenteral transdermal agents, the paste attached to the affected part is a component having an analgesic anti-inflammatory effect on the sheet-like envelope of elastic nonwoven fabric and the like, and an agent and an adhesive such as L-menthol, glycol succinate, red pepper extract, and nava It is applied so that it does not fall off the affected part, and it irritates the sore spot and promotes blood circulation so that the pain is forgotten. Unlike acupuncture, electric treatment device, moxibustion, and cupping, it does not cause any pain in the human body. Although it is an adhesive procedure, it does not show side effects and rejection in the human body, but it often causes side effects such as skin rashes and allergies and performs only simple functions such as cold pack (ice pack) or hot pack. Only the muscle recovery effect of the analgesic effect used There is a problem that does not have a fundamental therapeutic effect, but rather degenerative arthritis or senile arthritis, tendonitis that causes tendon inflammation, inflammation of the shoulders, wrists, wrists, wrists, knees, spines, etc. Using will grow the bottle.

       As described above, the general pars (patch) is an anti-inflammatory analgesic such as menthol, salicylic acid methyl, and camphor as an active ingredient, rather than a remedy, it temporarily acts as an adjuvant treatment to help relieve pain and swelling and help the body heal itself naturally. The cooling effect that gives a 'hot' heat to forget the pain or 'cheap' gives the refreshing feeling to forget the pain, that is, to stimulate the painful area and promote blood circulation to forget the pain.

        Menthol, the main ingredient of pars, has an analgesic effect that stimulates the local area to make it dull, and disinfects, antiseptic, and refreshes. Methyl salicylic acid acts on the peripheral area of pain-causing tissues to relieve pain. As a stimulating action, the feeling of cooling, molar preservation, tocopherol acetate to improve peripheral blood circulation, capsaicin has thermal stimulation and local analgesic action.

      For example, as an adjuvant treatment for muscle pain, bruises, back pain, joint pain, neuralgia, etc., Kulpas cools down the skin, relieves pain, constricts blood vessels, constricts blood vessels, and delays inflammation accordingly. It is effective to apply cool paste at the beginning of fracture within 48 hours, and hot paste is used for hot compressing, expanding the skin and vascular lymphatic vessels, promoting circulation of blood and lymph fluids, reducing the sensitivity of nerves and relieving pain. There is an effect to help the recovery of neuralgia, but because it accelerates the inflammatory action, there is a problem that should be avoided in inflammatory diseases, so the damage caused by misuse by the user carelessly when using the pars.

In addition, oral administration of oral administration of a specific drug has a fatal problem of being selectively used only by serious patients because the therapeutic effect is good compared to pars when applied to arthritis, but causes severe gastrointestinal disorders.

It is an external anti-inflammatory drug for the purpose of treating arthritis as well as simple skin irritation or poultice effect by improving the above-mentioned problems, that is, the drug is manufactured so that the drug penetrates directly into the blood through the skin at a constant rate for a long time to maintain its efficacy. As a patch using the drug delivery system (DDS), so-called drug ice packs and drug hot packs have been developed, which adds a drug treatment effect to the analgesic effect caused by poultice for a long period of time. .

           However, the conventional patch agent penetrates the skin when attached to the skin, and the drug enters the blood and exerts its effect. Unlike the simple function of pars, the patch has excellent analgesic and anti-inflammatory effects, but the active ingredient is not an herbal ingredient derived from natural products. It is a compound, and it is only a specific function, so it does not cover the symptoms of degenerative change (arthritis, rheumatism, etc.) due to complex factors, and the therapeutic effect is insignificant. Insufficient effect to fundamentally protect bone tissue of osteoporosis or joint disease caused, and even if drug absorption rate or absorption rate is good, there is a problem in the means of administration such as pars, so sweat does not come out well and adhesion is poor. Pharmacological effect by combined action You will not be able to see enough.

    In addition, conventional chemotherapeutic drugs, such as those used for arthritis and rheumatism, have side effects such as rashes, seizures, and dermatitis, which allergic symptoms occur, which hinders the long-term use of the drug. It is very important to develop it.

Also, it is known that herbal medicines can have analgesic, yangyang, astringent, anti-inflammatory effects on back pain, neck pain, and shoulder pain.The herbal medicines such as baekbaek soft extract, sanchija soft extract and sancho soft extract are mixed with adhesive materials and attached to the affected area. In recent years, the development of therapeutics using herbal medicines, which are widely known and have no toxicity and side effects, have been actively made.

          As a prior art, Korean Patent Publication No. 98-033687 discloses 40-60% of a fine powder bioceramic emitting far infrared rays, 10-20% of chitosan in a fine powder state, and an ABS resin of fine powder state (Acrylonitrile-Butadiene-Styrene Resin). ) 30 to 40% is blended to form a high-temperature melt composition formed by melting at a high temperature of 180 ℃ to 220 ℃, Korean Utility Model Registration No.0209111 is a raw material of fine charcoal and ceramic (jade, germanium, elvan, ferrite) By applying a layer of gelatin and attaching it to the affected area, a substance that is beneficial to the human body enters the subcutaneous tissue and strengthens the immune system, thereby initiating a charcoal far-infrared parser, which promotes a therapeutic effect, but it causes main effects such as allergy and dermatitis. Or the active ingredient was composed of a functional substance or a simple herbal medicine that had a problem that its use is limited to the poultice effect such as bruises.

          In addition, the Korean Patent Registration (Notice date: October 25, 2002) "The herbal patch" is a combination of herbal medicines gardenia and raw sulfur, which is a natural medicine used to prevent side effects of organic compounds and pain relief / anti-inflammatory Provides herbal patch for effective pain relief of sprains, sprains, bruises, myalgia, etc.Because it also lacks the complex effect by organic binding of each component, it is a single herbal patch that suppresses inflammatory reaction by simple poultice instead of bone protection. There is a problem that its use is limited, such as analgesic effect.

      The present invention has been made to solve the above-mentioned problems, the object of the present invention is a multi-drug compound having a proper composition ratio of the cold vinegar having a unique pharmacological action, such as bone tissue protection, creation, fresh sulfur, adding sugar as a solvent as a solvent in a multi-step Health by forming a coating composition with a patch composition extracted from hot water through heating and filtration, and an adhesive substance using the same as an active ingredient, and forming a coating composition on the outer support and mixing the functional material with micropore to form a functional material. It is a combination of herbal medicines with no side effects such as skin allergies, and it has no side effects such as skin allergies. When applied or applied to the affected areas such as waist, joint, neck, etc. Anti-inflammatory analgesic effect due to synergistic effect It is an object of the present invention to provide a patch composition for a poultice containing a herbal extract to realize an excellent effect on pain relief and treatment and prevention and a healthy poultice paste using the same.

Referring to the configuration of the present invention for achieving the above object in detail as follows.

The present invention provides a patch composition for a poultice containing herbal extracts for pain relief and treatment of muscle pain, bruises, back pain, arthralgia, neuralgia,

 As a solvent, 20 liters of water is added to 600 g of the mixed herbal medicines, which have the same medicinal properties (1: 1: 1: 1: 1: 1, weight ratio) of cold grass, rice cakes, fresh green grass, and Angelica, which have a unique pharmacological action. Next, the solvent is evaporated by heating at an extraction temperature of 90 to 100 ° C. for 12 to 24 hours, and then filtered and extracted.

The filtrate extracted by filtration as described above was concentrated under reduced pressure again at 50-60 ° C. to obtain a fluidity X. The preferred extraction solvent may be pure water or an aqueous alcohol solution such as ethanol or methanol, and the extraction and filtration were preferably repeated one or more times. Also, as an active ingredient of the present invention, each herbal medicine may be extracted alone, but in principle, the herbal medicines may be extracted together. When the herbal medicine of the present invention is heated by adding a solvent, the decomposition of the extract does not occur by heating to 100 ° C. or less. Do not

         In addition, the patch composition for the poultice containing the herbal extract extracted as described above is mixed with paper to form the pores to form a functional mineral material in the support material, and adhered with a conventional adhesive to the outer shell to emit far-infrared radiation and anion Forming the release paper, as a base contact cloth as a whole, the skin 11, the adhesive layer 12, the pharmaceutical composition layer 13 formed of a coating film of the patch composition for the adhesive of the adhesive material, and the release paper 14 peeled off Form the poultice pars 10.

          As the base substrate for emitting far-infrared radiation and anion of the present invention, the outer shell 11 is pulverized with 300 mesh in 25% (weight ratio) of pulping paper pulp mixed with wood pulp at a mixing ratio of 2: 1. A mixture of 15% (weight ratio) of jade powder, 15% (weight ratio) of biotite, and 35% (weight ratio) of ocher powder is beaten, and then 10% (weight ratio) of the total mixed material as a surface agent The cut paper was cut into paper in a conventional paper machine and cut into a conventional parsed paper as combined paper.

              As a support material, natural doc pulp is a strong fiber of bast fiber, and has high viscosity and strong binding ability, so as to contain the far-infrared radiation materials ocher, jade and biotite powder well.

            As the surface material added to the outer cover as the adhesive cloth, rosin increases the binding property between the paper and pulp to improve morphological stability, and also has excellent adhesiveness when the paste is attached to the skin to enable the use of the patch for a long time. The powder is effectively penetrated, the pores are formed in the outer shell, and the air permeability is good and the far-infrared radiation area and the ion generating area are maximized, so that it is easy to continuously infiltrate the skin with the medicinal herb active ingredient of the patch composition for a poultice containing the herbal extract. do.

           In addition, the outer skin of the present invention has the durability of morphological stability by combining the tough fiber of the bast fiber with the viscous of ocher, the durability of morphological stability by the combination of viscosity and binding, and the skin by far-infrared radiation of biotite gelatin It activates the skin by improving blood circulation and promotes metabolism, and its functional effect is maximized without adding extra nutrients by ocher moisture and fat adsorption action and soft skin regeneration effect by mineral ingredients.

         Germanium contained in biotite, which emits large amount of far infrared rays, has antibacterial, antibacterial, anti-fungal and harmful gas adsorption, and emits large amount of negative ions. It is a substance that overcomes the limitations of the natural healing, antitumor, analgesic, and lipid metabolism, and is known to have an excellent effect on senile osteoporosis, hypertension, hepatitis and arthritis. It is known to promote tongue circulation and metabolism and to treat neuralgia and arthritis.

            The adhesive usable in the present invention may be formed by applying an adhesive resin containing ordinary gum arabic or starch or a polymer compound of water-soluble polyvinyl alcohol (PVA) -polyvinyl pyrrolidone (PVP). It can be selected from the materials and uses the functional adhesive cloth which has elasticity and morphological stability at the same time to strengthen the adhesiveness and adhesion of the bent parts such as elbows and knees, and the pores are formed to realize a cool and soft poultice effect.

         As an active ingredient of the present invention, cold herb as a herbal medicine is a perennial herb of the dicotyledon plant plywood group currency plant Hyunsam, Korea (Gyeonggi, Gangwon, Yellow Sea, Pyeongbuk, Hamnam, Hambuk), Japan, China, Inhabits in damp areas of mountains, such as Siberia, cold herbs of dried roots are effective for hyperhidrosis, each, rheumatism, arthritis, dryness, expectoration, migraine, edema, diuresis, pain, stroke, constipation.

         Creation is the root of a plant called Azalea, which belongs to the Asteraceae, taste is slightly aromatic (mint like peppermint), bitter and warm in nature, and its effects are 燥濕 健脾 (humidity dryness), 去 風濕 (hot wind) It is written in Chinese medicine that removes moisture (swelling or fluid flow) from our body, and it is generally used in case of back pain, leg or knee swelling (arthritis, etc.) Used as a digestive or joint pain medication.

         As the root of the shovel, there are about 1.5% of essential oil and carotene, inulin, rubbery, and alkaloid reactions.The main components of the seed of the shovel's root, attic, are atlactilodine and a small amount of acetylatlactilinodinol, atlactilodidin, and elemol. It is heard and reported.

       The above generation may be used alone or in combination, and the rhizome of the generation may be dried, pulverized into fine powders, and the extraction time by adding water to the solvent in the hot water extraction through a multi-stage purification process with a solvent is increased. This highly purified purified extract has the effect of inhibiting the activity of inflammatory factors and can be used for both oral or parenteral administration.

          The creation of the pharmacological effect as described above can be said that the roots of Joseon shovel are more equivalent to the creation of narratives and pictures in the old Donghak literature.The creation is sweet and spicy and warm, soothing, hematopoietic and urinating. In motion therapy, it is very important to combine diarrhea and diarrhea in folk remedies with urinary tract, swelling, dizziness and urinary tract, sweating medicine, etc. It is often used to stop vomiting and to treat indigestion, diabetes, cough and gout.

         Jihwang is a root of perennial herbaceous plants belonging to the Hyunsam family. Fresh roots of fresh roots are dried, dried ones are dried and dried in yellow wine, and steamed and sun-dried 9 times. It is sweet and bitter, it is cold and its effect is to lower the heat, to clear the blood, and to make the essence. The clinical application and the method is that the heat enters the body of young blood. Feeling thirsty, having a deep reddish tongue, dry cough, bloody coughing, vomiting blood, nosebleeding, bloody bleeding in the urine or stool, fever, swelling and soreness in the body Used for diabetes, etc.

         Thus, as the active ingredient of the present invention, raw jihwang is very cold and bitter taste of the ingredients of the medicine to reduce the anger and fever and sweat less, hemostasis action when the nose bleeds or blood due to fever, hemostasis, skin spots due to heat When it occurs, it removes the spots, and when there is bleeding of the uterus, it removes the blood, removes swelling or insomnia, it is also effective in urine.

In addition, it is disclosed in Korean Patent No. 10-0374937, "Pharmaceutical Composition for Osteoporosis Prevention and Treatment," which is effective in treating and preventing osteoporosis without side effects because it is active to proliferate osteoblasts and inhibit the growth of osteoclasts. .

         Dongguk is a root of Seunggeumcho, which is indigenous to the mountain as a lily and perennial herb. The stem grows about 1m from the big root, and the leaves are next to idols. In summer, small white flowers bloom and the fragrance is unusual. It is a representative of the blood donor and active in the hematopoietic organs, which has a remarkable effect on anemia, aplastic anemia, postpartum bleeding and traumatic bleeding. Women's physiological disorders, bruises, blood and internal bleeding to reduce the pain, improve blood circulation, and also effective in postpartum abdominal pain, constipation, anemia, headache, blood disorders, especially clearing blood.

The donkey used in the present invention uses dried roots of the true donkey and is a complex herbal medicine mixed with an appropriate blending ratio, such as single or other liquids, and used in the prescription of arthritis to control cartilage destruction by controlling factors involved in cartilage destruction. You can stop it.

 The pharmacological efficacy of these materials has been introduced in detail by various herbal literature and research, including synergism.

Therefore, the present inventors have confirmed that the extract of cold grass, creation, raw yellow sulfur, Angelica sinensis which has the above-mentioned medicinal effects is a herbal composition which has no poison and no side effect and has excellent therapeutic effect on arthritis, and the composition thus prepared is muscle pain, bruise, back pain, The present invention was completed by confirming that it is effective in preventing and treating arthritis and osteoporosis, as well as pain relief of arthralgia and neuralgia.

The patch composition for a poultice containing the herbal extract as a composite herbal composition of the present invention can be selectively and appropriately added to each of the herbal extracts within a range that effectively maintains a therapeutic effect, so that the extract, liquid, powder, pill, tablet, capsule, etc. And also can be prepared as a patch and can be useful to replace the existing chemotherapeutic treatment.

In addition to the patch composition for a poultice containing the herbal extracts described above, as a base base of the paste (patch) attached to the affected part, the skin containing far-infrared radiation and anion is released, and the composition containing the herbal extracts is combined with the health paste. As it forms, the pores are formed on the affected area to improve ventilation, and the area of far-infrared radiation and ion generation are maximized, and each functional substance beneficial to the human body enters the subcutaneous tissue and strengthens the immune system, thereby promoting a therapeutic effect.

 In other words, the present invention was applied to the affected area by applying the medicinal herb selected the most effective herbal medicine based on clinical research and actual treatment effect, and to stimulate a wide range of meridians, which is performed by the principle of traditional Chinese medicine The flow of Gi and blood flows by the synergistic treatment effect by drug stimulation of weak penetration and organic combination such as far-infrared radiation and anion release, which are superior to various methods such as acupuncture, moxibustion, acupressure, and magnet attachment. By maintaining the balance, there is a therapeutic and preventive effect that activates cells and strengthens immunity to promote health.

After all, the present invention is the same as the combined function of the operation of Chinese medicine, such as swelling, moxibustion, plaster, and pain relief and disease prevention of painful parts and vitality to the body by pain relief function as well as promoting blood circulation and of course metabolism improvement The blowing function will be performed at the same time.

Example 1

First step: hot water extraction of the patch composition for poultice containing the herbal extract

 20 liters of water is added as a solvent to 600 g of the mixed herbal medicines, which have the same medicinal properties (1: 1: 1: 1: 1: 1, weight ratio) of cold grass, creation, raw sulfur, and Angelica, which have unique pharmacological action. Then, the solvent was evaporated by heating at an extraction temperature of 90 to 100 ° C. for 12 to 24 hours, followed by filtration.

The filtrate extracted by filtration as described above was concentrated under reduced pressure at 50-60 ℃ again to obtain a fluidity X.

Second Step: Formation of Pars Containing a Patch Composition for Poultice

Form a pharmaceutical composition layer with a patch patch composition containing a herbal extract extracted in the hot water extraction process of the patch patch composition for the poultice, and the mixture is made up to form functional pores to form pores in the hanji support far infrared radiation and anion The outer shell 11, the adhesive layer 12, the pharmaceutical composition layer 13, and the release paper 14, which are generally in the form of a paste, are formed by adhering the outer shell with an adhesive like a normal sandwich and forming a release paper at the bottom. Formed by lamination to complete the poultice paste.

Test Example 1

In order to compare the efficacy effect of pars using the patch composition for poultice containing the herbal extract according to the present invention and pars including a commercial patch composition, 20 patients suffering from muscle pain, bruises and joint pain as a control group Each was administered for 3 days and the effect of persistence and adhesion (adhesion) of the poultice effect and efficacy was determined as an evaluation item (no effect 1 point-normal 3 points-very satisfied 5 points), and the results were observed. Table 1 Shown in

               division         Patch agent of the present invention               Commercial product  Poultice effect                 5.2              3.9  Persistence                 5.5              3.4  Adhesion                 4.8              4.2

As shown in Table 1, the herbal patch of the present invention has a synergistic synergistic effect of the herb composite composition and the functional sheet of the skin as compared to the control group, and the effect is excellent when attached to the affected area of muscle pain, bruises, and joint pain. have.

The present invention described above is not limited to the above-described embodiment as various substitutions and changes can be made by those skilled in the art without departing from the technical spirit of the present invention. .

Thus, the present invention is a complex herbal medicine with an appropriate composition ratio of a patch agent composition having the unique pharmacological action such as bone tissue protection, creation, live sulfur, and Angelica as an active ingredient, and an adhesive material forming a film using the same as germanium This complex functional material combines with the mixed paper and outer skin to form fine pores, forming a healthy poultice paste, and has no side effects such as skin allergies with the main ingredient of herbal medicine, and is applied to the affected areas such as waist, joint, neck, etc. Anti-inflammatory analgesic action by the combined synergistic synergistic effect of complementary functions such as pharmacological effect from the derived herbal medicine and the thermal treatment effect of the functional substance which is very beneficial to the human body. It can be used as a herbal compound for muscle pain, joint pain, It is effective in low back pain, so it is very effective for pain patients such as elderly and middle aged people who complain of chronic pain.

1 is a perspective view of a healthy poultice paste according to the present invention

Figure 2 is a cross-sectional configuration of the healthy poultice pars according to the present invention

<Explanation of symbols for main parts of drawing>

10: poultice paste 11: shell

12: Adhesive layer 13: Pharmaceutical composition layer

14: Release paper

Claims (2)

 In the patch composition for poultice containing herbal extracts for the purpose of alleviating the pain and treatment of muscle pain, bruises, back pain, joint pain, neuralgia,  As a solvent, 20 liters of water is added to 600 g of the mixed herbal medicines, which have the same medicinal properties (1: 1: 1: 1: 1: 1, weight ratio) of cold grass, rice cakes, fresh green grass, and Angelica, which have a unique pharmacological action. Then, the patch composition for a poultice containing a herbal extract characterized in that the extraction temperature is heated to 90 to 100 ℃ for 12 to 24 hours by evaporating the solvent and then filtered. The method according to claim 1, wherein the pharmaceutical composition layer 13 having a film formed of an adhesive material comprising the herbal patch extract containing the herbal extract as an active ingredient and a fibrous doc and wood pulp as a base adhesion cloth are mixed. 25% (weight ratio) of pulverized paper pulp mixed with 1 is mixed with 15% (weight ratio) of finely ground jade powder of 300 mesh, biotite powder 15% (weight ratio), and yellow clay powder 35% (weight ratio) 10% (weight ratio) rosin as a surface agent, and the laminated outer sheath 11, the adhesive layer 12, and the release paper 14 peeled to form micropores were laminated to form a healthy poultice paste 10. Healthy poultice pars using patch composition for poultice containing herbal extract