KR20050106038A - 심장질환 및 신장질환의 치료를 위한 아데노신 ａ1 수용체길항제 - Google Patents

심장질환 및 신장질환의 치료를 위한 아데노신 ａ1 수용체길항제 Download PDF

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Publication number
KR20050106038A
KR20050106038A KR1020057015605A KR20057015605A KR20050106038A KR 20050106038 A KR20050106038 A KR 20050106038A KR 1020057015605 A KR1020057015605 A KR 1020057015605A KR 20057015605 A KR20057015605 A KR 20057015605A KR 20050106038 A KR20050106038 A KR 20050106038A
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South Korea
Prior art keywords
patient
hydroxy
formula
adenosine
lower alkyl
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Korean (ko)
Inventor
로렌 오츠키
하워드 씨. 디트리치
케네스 제이. 위더
로렌드 블란츠
스콧 톰슨
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노바카르디아, 인코포레이션
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Publication of KR20050106038A publication Critical patent/KR20050106038A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057015605A 2003-02-24 2004-02-24 심장질환 및 신장질환의 치료를 위한 아데노신 ａ1 수용체길항제 Ceased KR20050106038A (ko)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US44995303P 2003-02-24 2003-02-24
US60/449,953 2003-02-24
US45049903P 2003-02-25 2003-02-25
US45050003P 2003-02-25 2003-02-25
US60/450,499 2003-02-25
US60/450,500 2003-02-25
US45132603P 2003-02-28 2003-02-28
US60/451,326 2003-02-28
US46481303P 2003-04-21 2003-04-21
US46481203P 2003-04-21 2003-04-21
US46481503P 2003-04-21 2003-04-21
US46481103P 2003-04-21 2003-04-21
US60/464,815 2003-04-21
US60/464,811 2003-04-21
US60/464,812 2003-04-21
US60/464,813 2003-04-21

Publications (1)

Publication Number Publication Date
KR20050106038A true KR20050106038A (ko) 2005-11-08

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Family Applications (1)

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KR1020057015605A Ceased KR20050106038A (ko) 2003-02-24 2004-02-24 심장질환 및 신장질환의 치료를 위한 아데노신 ａ1 수용체길항제

Country Status (9)

Country Link
US (1) US20040229901A1 (https=)
EP (2) EP2087888A1 (https=)
JP (1) JP2006518765A (https=)
KR (1) KR20050106038A (https=)
AU (1) AU2004216133B2 (https=)
BR (1) BRPI0407494A (https=)
CA (1) CA2516730A1 (https=)
MX (1) MXPA05008805A (https=)
WO (1) WO2004075856A2 (https=)

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US20090197900A1 (en) * 2007-03-29 2009-08-06 Howard Dittrich Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
BRPI0821483A2 (pt) * 2007-12-27 2015-06-16 Bayer Animal Health Gmbh Tratamento de doença cardíaca usando beta-bloqueadores
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JP2006518765A (ja) 2006-08-17
CA2516730A1 (en) 2004-09-10
MXPA05008805A (es) 2006-02-22
WO2004075856A2 (en) 2004-09-10
WO2004075856A3 (en) 2005-03-31
EP2087888A1 (en) 2009-08-12
AU2004216133A1 (en) 2004-09-10
EP1603545A2 (en) 2005-12-14
US20040229901A1 (en) 2004-11-18
BRPI0407494A (pt) 2006-02-14

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