ATE180482T1 - Xanthinderivate zur behandlung der demenz - Google Patents

Xanthinderivate zur behandlung der demenz

Info

Publication number
ATE180482T1
ATE180482T1 AT92119080T AT92119080T ATE180482T1 AT E180482 T1 ATE180482 T1 AT E180482T1 AT 92119080 T AT92119080 T AT 92119080T AT 92119080 T AT92119080 T AT 92119080T AT E180482 T1 ATE180482 T1 AT E180482T1
Authority
AT
Austria
Prior art keywords
chem
substituted
same
unsubstituted
different
Prior art date
Application number
AT92119080T
Other languages
English (en)
Inventor
Suzuki Fumio
Shimada Junichi
Kato Hiromasa
Ishii Akio
Shiozaki Shizuo
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE180482T1 publication Critical patent/ATE180482T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92119080T 1991-11-08 1992-11-06 Xanthinderivate zur behandlung der demenz ATE180482T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29326991 1991-11-08

Publications (1)

Publication Number Publication Date
ATE180482T1 true ATE180482T1 (de) 1999-06-15

Family

ID=17792638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92119080T ATE180482T1 (de) 1991-11-08 1992-11-06 Xanthinderivate zur behandlung der demenz

Country Status (5)

Country Link
US (1) US5447933A (de)
EP (1) EP0541120B1 (de)
AT (1) ATE180482T1 (de)
CA (1) CA2082325A1 (de)
DE (1) DE69229257D1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62247149A (ja) * 1986-04-18 1987-10-28 Mitsubishi Electric Corp 内燃機関の燃料制御装置
DE3843117A1 (de) * 1988-12-22 1990-06-28 Boehringer Ingelheim Kg Neue xanthinderivate mit adenosin-antagonistischer wirkung
US5395836A (en) * 1993-04-07 1995-03-07 Kyowa Hakko Kogyo Co., Ltd. 8-tricycloalkyl xanthine derivatives
DE4316576A1 (de) * 1993-05-18 1994-11-24 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 1,3-Dipropyl-8-(3-Oxocyclopentyl)-xanthin
WO1995031460A1 (fr) * 1994-05-17 1995-11-23 Kyowa Hakko Kogyo Co., Ltd. Procede pour produire un derive de xanthine
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
ATE247655T1 (de) * 1994-12-13 2003-09-15 Euro Celtique Sa Dreifachsubstituierte thioxanthine
CA2218548A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited Xanthines and their therapeutic use
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5786360A (en) 1996-11-19 1998-07-28 Link Technology Incorporated A1 adenosine receptor antagonists
US6248746B1 (en) 1998-01-07 2001-06-19 Euro-Celtique S.A. 3-(arylalkyl) xanthines
US6263850B1 (en) 1999-08-03 2001-07-24 Visteon Global Technologies, Inc. Integrated air induction module for gasoline engines
JP2003513976A (ja) 1999-11-12 2003-04-15 バイオジェン インコーポレイテッド アデノシンレセプターアンタゴニストおよびこれを作製し使用する方法
SI1230243T1 (sl) 1999-11-12 2009-08-31 Biogen Idec Inc Policikloalkilpurini kot antagonisti adenozinskega receptorja
WO2004074247A2 (en) * 2003-02-19 2004-09-02 Endacea, Inc. A1 adenosine receptor antagonists
US20040229901A1 (en) * 2003-02-24 2004-11-18 Lauren Otsuki Method of treatment of disease using an adenosine A1 receptor antagonist
US7247639B2 (en) * 2003-06-06 2007-07-24 Endacea, Inc. A1 adenosine receptor antagonists
CA2528367A1 (en) * 2003-06-09 2004-12-23 Endacea, Inc. A1 adenosine receptor antagonists
WO2006091936A2 (en) * 2005-02-25 2006-08-31 Adenosine Therapeutics, Llc Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines
AU2007288312A1 (en) * 2006-08-22 2008-02-28 Novacardia, Inc. KW-3902 conjugates that do not cross the blood-brain barrier
EP2222676A4 (de) * 2007-12-21 2011-10-26 Endacea Inc A1-adenosinrezeptorantagonisten

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA724173A (en) * 1965-12-21 Goldner Herbert Process for the production of xanthine derivatives
DE1245969B (de) * 1967-08-03 VEB Arzneimittelwerk Dresden, Radebeul Verfahren zur Herstellung von Xanthinderivaten
US4576947A (en) * 1967-12-16 1986-03-18 Hoechst Aktiengesellschaft Pharmaceutical compositions
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
EP0193599A1 (de) * 1984-09-07 1986-09-10 The General Hospital Corporation Pestizidemittel aus xanthin
GB8510758D0 (en) * 1985-04-27 1985-06-05 Wellcome Found Compounds
DE3843117A1 (de) * 1988-12-22 1990-06-28 Boehringer Ingelheim Kg Neue xanthinderivate mit adenosin-antagonistischer wirkung
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
JPH06102662B2 (ja) * 1989-09-01 1994-12-14 協和醗酵工業株式会社 キサンチン誘導体
DE4019892A1 (de) * 1990-06-22 1992-01-02 Boehringer Ingelheim Kg Neue xanthinderivate
CA2061544A1 (en) * 1991-02-25 1992-08-26 Fumio Suzuki Xanthine compounds

Also Published As

Publication number Publication date
EP0541120A3 (en) 1993-07-21
US5447933A (en) 1995-09-05
DE69229257D1 (de) 1999-07-01
CA2082325A1 (en) 1993-05-09
EP0541120A2 (de) 1993-05-12
EP0541120B1 (de) 1999-05-26

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