KR20050084378A - 보린산 착물을 함유하는 항생제 및 그 이용방법 - Google Patents

보린산 착물을 함유하는 항생제 및 그 이용방법 Download PDF

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Publication number
KR20050084378A
KR20050084378A KR1020057011194A KR20057011194A KR20050084378A KR 20050084378 A KR20050084378 A KR 20050084378A KR 1020057011194 A KR1020057011194 A KR 1020057011194A KR 20057011194 A KR20057011194 A KR 20057011194A KR 20050084378 A KR20050084378 A KR 20050084378A
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KR
South Korea
Prior art keywords
alkyl
substituted
aryl
unsubstituted
species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020057011194A
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English (en)
Korean (ko)
Inventor
빙 리
스테펜 제이 벤코빅
Original Assignee
아나코르 파마슈티칼스 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 아나코르 파마슈티칼스 인코포레이티드 filed Critical 아나코르 파마슈티칼스 인코포레이티드
Publication of KR20050084378A publication Critical patent/KR20050084378A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/022—Boron compounds without C-boron linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020057011194A 2002-12-18 2003-12-18 보린산 착물을 함유하는 항생제 및 그 이용방법 Ceased KR20050084378A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US43437502P 2002-12-18 2002-12-18
US60/434,375 2002-12-18
US43609502P 2002-12-23 2002-12-23
US60/436,095 2002-12-23
US43784903P 2003-01-03 2003-01-03
US60/437,849 2003-01-03

Publications (1)

Publication Number Publication Date
KR20050084378A true KR20050084378A (ko) 2005-08-26

Family

ID=32686073

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057011194A Ceased KR20050084378A (ko) 2002-12-18 2003-12-18 보린산 착물을 함유하는 항생제 및 그 이용방법

Country Status (11)

Country Link
US (2) US20040224923A1 (enExample)
EP (2) EP1581500A4 (enExample)
JP (2) JP2006511613A (enExample)
KR (1) KR20050084378A (enExample)
CN (1) CN101928295A (enExample)
AU (1) AU2003299821B2 (enExample)
BR (1) BR0317564A (enExample)
CA (1) CA2509645A1 (enExample)
MX (1) MXPA05006685A (enExample)
NZ (1) NZ540870A (enExample)
WO (1) WO2004056322A2 (enExample)

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CA2473238A1 (en) 2002-01-10 2003-07-24 The Penn State Research Foundation Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids
US7390806B2 (en) * 2002-12-18 2008-06-24 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
CA2509645A1 (en) * 2002-12-18 2004-07-08 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
AR049915A1 (es) * 2004-06-14 2006-09-13 Anacor Pharmaceuticals Inc Compuestos con contenido de boro y metodos de uso de los mismos
AR049916A1 (es) * 2004-06-14 2006-09-13 Anacor Pharmaceuticals Inc Usos anti-parasitarios de complejos de acido borinico
US7393856B2 (en) 2004-06-14 2008-07-01 Anacor Pharmaceuticals, Inc. Anti-viral uses of borinic acid complexes
AU2006214247C1 (en) 2005-02-16 2012-11-08 Anacor Pharmaceuticals, Llc Boron-containing small molecules
US20060217347A1 (en) * 2005-03-24 2006-09-28 David Perry Topical formulations of borinic acid antibiotics and their methods of use
WO2007079119A2 (en) * 2005-12-28 2007-07-12 Anacor Pharmaceuticals, Inc. Process for manufacturing picolinate borinic esters
BRPI0621279B1 (pt) 2005-12-30 2021-07-20 Anacor Pharmaceuticals, Inc Moléculas pequenas contendo boro
CA2642583C (en) 2006-02-16 2016-08-23 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
WO2007146965A2 (en) * 2006-06-12 2007-12-21 Anacor Pharmaceuticals, Inc. Compounds for the treatment of periodontal disease
US20070286822A1 (en) * 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
WO2008064345A2 (en) * 2006-11-22 2008-05-29 Anacor Pharmaceuticals, Inc. Microorganism killing compounds
CN102014927A (zh) 2008-03-06 2011-04-13 安纳考尔医药公司 作为抗炎药的含硼的小分子
EP2285384A4 (en) * 2008-05-12 2012-04-25 Anacor Pharmaceuticals Inc BORN SMALL MOLECULES
WO2010028005A1 (en) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010027975A1 (en) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US9493489B2 (en) 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
AU2009335744A1 (en) * 2008-12-17 2010-07-15 Anacor Pharmaceuticals, Inc. Polymorphs of (S)-3-aminomethyl-7-(3-hydroxy-propoxy) -3H-benzo[c][1,2] oxaborol-1-ol
JP2013500974A (ja) * 2009-07-28 2013-01-10 アナコール ファーマシューティカルズ，インコーポレイテッド 三置換ホウ素含有分子
AP4039A (en) 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
MX2012002031A (es) * 2009-08-19 2012-07-04 Anacor Pharmaceuticals Inc Moleculas pequeñas que contienen boro como agentes antiprotozoarios.
US20110124597A1 (en) * 2009-09-25 2011-05-26 Anacor Pharmaceuticals, Inc. Boron containing small molecules
US9346834B2 (en) 2009-10-20 2016-05-24 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
WO2011060199A1 (en) * 2009-11-11 2011-05-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2011094450A1 (en) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Boron-containing small molecules
WO2011116348A1 (en) 2010-03-19 2011-09-22 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agent
SMT202100643T1 (it) 2010-09-07 2022-01-10 Anacor Pharmaceuticals Inc Derivati del benzossaborolo per il trattamento delle infezioni batteriche
US8669207B1 (en) 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
EP2950644B1 (en) 2013-01-30 2017-07-19 AgroFresh Inc. Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
WO2015026548A1 (en) * 2013-08-20 2015-02-26 3M Innovative Properties Company Boron-silane polyether complex
KR101756785B1 (ko) * 2015-03-10 2017-07-12 한국화학연구원 4배위 유기 붕소 화합물의 제조방법
EP3426029B1 (en) 2016-03-07 2023-08-30 AgroFresh Inc. Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
IL248149B (en) 2016-09-29 2020-03-31 Garti Nissim Formulations of dilutable cannabinoids and processes for their preparation
IL248150B (en) 2016-09-29 2018-05-31 Garti Nissim A method for selective extraction of cannabinoid from plant origin
KR102465919B1 (ko) 2016-10-05 2022-11-10 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. 미코박테리아 감염의 치료를 위한 헤테로아릴트리플루오로보레이트 화합물
MA52337A (fr) 2017-03-01 2021-03-03 Anacor Pharmaceuticals Inc Nouveaux analogues d'oxaborole et utilisations de ces derniers
AU2018230580A1 (en) * 2017-03-09 2019-09-19 The Penn State Research Foundation Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase
CA3110179A1 (en) * 2018-08-20 2020-02-27 Senseonics, Incorporated Mediated drug release for reducing in vivo analyte indicator degradation
US20230340530A1 (en) 2020-08-31 2023-10-26 Pfizer Inc. Methods of Protecting RNA
US12357552B2 (en) 2021-03-09 2025-07-15 Juris GERMANAS Hydroxyquinoline compounds and methods of use as pigment modifying agents

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KR950012756B1 (ko) * 1989-10-18 1995-10-21 훽스트 아크티엔게젤샤프트 벼의 잡초의 방제방법
US5348947A (en) * 1993-05-07 1994-09-20 American Cyanamid Company Diarylboron ester and thioester fungicidal agents
US5348948A (en) * 1993-05-07 1994-09-20 American Cyanamid Company 2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal
JPH0952893A (ja) * 1995-08-10 1997-02-25 Yoshitomi Pharmaceut Ind Ltd キノロンカルボン酸誘導体の工業的な製造法およびその合成中間体
DE19829947A1 (de) * 1998-07-04 2000-01-05 Bayer Ag Elektrolumineszierende Anordnungen mit Bor-Chelaten
WO2000044387A1 (fr) * 1999-01-29 2000-08-03 Nitto Kasei Co., Ltd. Composes organobores presentant une activite de coccidiostats
CN1370170A (zh) * 1999-05-25 2002-09-18 宾夕法尼亚州研究基金会 Dna甲基转移酶抑制剂
DE10110051C2 (de) * 2001-03-02 2003-07-03 Clariant Gmbh Verfahren zur Herstellung von Boron- und Borinsäuren
JP2002322007A (ja) * 2001-04-27 2002-11-08 Shionogi & Co Ltd 有機ホウ素化合物を含有する植物用殺線虫剤
CA2473238A1 (en) * 2002-01-10 2003-07-24 The Penn State Research Foundation Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids
CA2509645A1 (en) * 2002-12-18 2004-07-08 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
US7390806B2 (en) * 2002-12-18 2008-06-24 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use

Also Published As

Publication number Publication date
JP2009161540A (ja) 2009-07-23
JP2006511613A (ja) 2006-04-06
CN101928295A (zh) 2010-12-29
AU2003299821A1 (en) 2004-07-14
US20040224923A1 (en) 2004-11-11
WO2004056322A3 (en) 2004-09-16
EP1581500A2 (en) 2005-10-05
MXPA05006685A (es) 2005-12-14
CA2509645A1 (en) 2004-07-08
US20080146803A1 (en) 2008-06-19
WO2004056322A2 (en) 2004-07-08
NZ540870A (en) 2008-09-26
EP1980564A1 (en) 2008-10-15
BR0317564A (pt) 2005-11-22
EP1581500A4 (en) 2008-03-05
AU2003299821B2 (en) 2010-02-18

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Patent event date: 20050617

Patent event code: PA01051R01D

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Patent event code: PA02012R01D

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PE0902 Notice of grounds for rejection

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Patent event code: PE09021S01D

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PE0601 Decision on rejection of patent

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Comment text: Final Notice of Reason for Refusal

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Patent event code: PE06011S01I