KR20050008717A - 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는약제학적 조성물 - Google Patents
레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는약제학적 조성물 Download PDFInfo
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- KR20050008717A KR20050008717A KR10-2004-7018479A KR20047018479A KR20050008717A KR 20050008717 A KR20050008717 A KR 20050008717A KR 20047018479 A KR20047018479 A KR 20047018479A KR 20050008717 A KR20050008717 A KR 20050008717A
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38154602P | 2002-05-17 | 2002-05-17 | |
| US60/381,546 | 2002-05-17 | ||
| PCT/EP2003/005188 WO2003097098A1 (en) | 2002-05-17 | 2003-05-16 | Pharmaceutical composition comprising a renin inhibitor, a calcium channel blocker and a diuretic |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020107028689A Division KR20100137026A (ko) | 2002-05-17 | 2003-05-16 | 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물 |
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| KR20050008717A true KR20050008717A (ko) | 2005-01-21 |
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| KR1020107028689A Ceased KR20100137026A (ko) | 2002-05-17 | 2003-05-16 | 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물 |
| KR1020137023159A Ceased KR20130109244A (ko) | 2002-05-17 | 2003-05-16 | 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물 |
Family Applications After (2)
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| KR1020107028689A Ceased KR20100137026A (ko) | 2002-05-17 | 2003-05-16 | 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물 |
| KR1020137023159A Ceased KR20130109244A (ko) | 2002-05-17 | 2003-05-16 | 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20050182042A1 (https=) |
| EP (2) | EP1507558B8 (https=) |
| JP (2) | JP5288678B2 (https=) |
| KR (3) | KR20050008717A (https=) |
| CN (1) | CN1655819A (https=) |
| AT (1) | ATE520417T1 (https=) |
| AU (1) | AU2003240669B2 (https=) |
| BR (1) | BR0310084A (https=) |
| CA (1) | CA2485081C (https=) |
| CY (2) | CY1112013T1 (https=) |
| DK (1) | DK1507558T3 (https=) |
| EC (1) | ECSP045428A (https=) |
| ES (1) | ES2369216T3 (https=) |
| IL (1) | IL164837A (https=) |
| LU (1) | LU92000I2 (https=) |
| MX (1) | MXPA04011383A (https=) |
| NO (1) | NO334382B1 (https=) |
| NZ (1) | NZ536555A (https=) |
| PL (1) | PL219032B1 (https=) |
| PT (1) | PT1507558E (https=) |
| RU (1) | RU2316318C2 (https=) |
| SI (1) | SI1507558T1 (https=) |
| WO (1) | WO2003097098A1 (https=) |
| ZA (1) | ZA200408442B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210149498A (ko) * | 2020-06-02 | 2021-12-09 | 이화여자대학교 산학협력단 | 플루나리진 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 |
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| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| US8168616B1 (en) | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| DK1507558T3 (da) * | 2002-05-17 | 2011-12-05 | Novartis Pharma Ag | Farmaceutisk sammensætning omfattende en renininhibitor, en calciumkanalblokker og et diuretikum |
| CA2525970C (en) | 2003-05-15 | 2011-03-22 | Roskamp Research, Llc | Use of nilvadipine for reducing amyloid deposition, amyloid neurotoxicity and microgliosis |
| AR047880A1 (es) * | 2004-02-17 | 2006-03-01 | Novartis Ag | COMBINACIoN DE UN INHIBIDOR DE RENINA Y DIURÉTICOS |
| NZ549535A (en) * | 2004-03-17 | 2010-11-26 | Novartis Ag | Use of aliskiren for treating renal and other disorders |
| MY148773A (en) * | 2004-03-17 | 2013-05-31 | Novartis Ag | Galenic formulations of organic compounds |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| ATE474601T1 (de) * | 2004-05-31 | 2010-08-15 | Almirall Sa | Kombinationen mit antimuskarin-wirkstoffen und pde4-hemmern |
| MY146830A (en) * | 2005-02-11 | 2012-09-28 | Novartis Ag | Combination of organic compounds |
| US20100240760A1 (en) * | 2005-03-22 | 2010-09-23 | Jessie Gu | Biomarkers for Efficacy of Aliskiren as a Hypertensive Agent |
| RU2008122712A (ru) * | 2005-11-08 | 2009-12-20 | Новартис АГ (CH) | Комбинация органических соединений |
| AR057882A1 (es) | 2005-11-09 | 2007-12-26 | Novartis Ag | Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra |
| GB0612540D0 (en) * | 2006-06-23 | 2006-08-02 | Novartis Ag | Galenical formulations of organic compounds |
| EP1891937A1 (en) * | 2006-08-25 | 2008-02-27 | Novartis AG | Galenic formulations of aliskiren |
| NZ577320A (en) * | 2006-11-07 | 2012-01-12 | Novartis Ag | CRYSTALLINE FORMS OF ALISKIREN HEMIFUMARATE N-(3-amino-2,2-dimethyl-3-oxopropyl)-2,7-di(1-methylethyl)-4-hydroxy-5-amino-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide |
| AR063597A1 (es) * | 2006-11-09 | 2009-02-04 | Novartis Ag | Nueva sal |
| CA2708004C (en) * | 2006-12-04 | 2015-12-01 | Promedior, Inc. | Conjoint therapy for treating fibrotic diseases |
| WO2008098992A1 (en) * | 2007-02-16 | 2008-08-21 | Novartis Ag | Use of organic compounds |
| EP1972335A1 (en) * | 2007-03-23 | 2008-09-24 | Krka | Solid dosage forms comprising aliskiren and pharmaceutically acceptable salts thereof |
| RU2363472C2 (ru) * | 2007-05-22 | 2009-08-10 | Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова Федерального агентства по здравоохранению и социальному развитию" | Способ профилактики и лечения кардиоваскулярных осложнений у больных с хронической болезнью почек, находящихся на гемодиализе, имеющих анурию |
| US8497243B2 (en) * | 2007-07-06 | 2013-07-30 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
| US9884899B2 (en) | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
| TWI500422B (zh) | 2007-10-05 | 2015-09-21 | Alzheimer S Inst Of America Inc | 以（－）－尼代地平（ｎｉｌｖａｄｉｐｉｎｅ）對映異構物減低類澱粉沉積、類澱粉神經毒性及微神經膠細胞增生之方法 |
| EP2062874B1 (en) | 2007-11-20 | 2014-12-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Process and intermediates for the preparation of aliskiren |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| RU2373932C1 (ru) * | 2008-05-20 | 2009-11-27 | Илья Николаевич Медведев | Способ коррекции уровня микровезикул в крови при артериальной гипертонии |
| RU2372079C1 (ru) * | 2008-05-20 | 2009-11-10 | Илья Николаевич Медведев | Способ коррекции уровня микровезикул в крови при артериальной гипертонии, дислипидемии и нарушении толерантности к глюкозе |
| JO3239B1 (ar) * | 2008-09-22 | 2018-03-08 | Novartis Ag | تركيبات جالينية من مركبات عضوية |
| RU2382644C1 (ru) * | 2008-11-05 | 2010-02-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию" | Способ коррекции гипертрофии левого желудочка у больных ибс в сочетании с гипертонической болезнью |
| SI2189442T1 (sl) | 2008-11-20 | 2015-03-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Postopek in intermediati za pripravo aliskirena |
| CA2755047C (en) * | 2009-03-11 | 2018-12-04 | Promedior, Inc. | Treatment methods for autoimmune disorders |
| PT2405928T (pt) * | 2009-03-11 | 2017-02-07 | Promedior Inc | Métodos de tratamento e de diagnóstico para patologias de hipersensibilidade |
| UA110323C2 (en) * | 2009-06-04 | 2015-12-25 | Promedior Inc | Derivative of serum amyloid p and their receipt and application |
| EP2987803B1 (en) | 2009-06-17 | 2018-08-29 | Promedior Inc. | Sap variants and their use |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| CN102247344A (zh) * | 2011-05-30 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种新型降血压组合物 |
| CN102552277A (zh) * | 2011-12-02 | 2012-07-11 | 邬林祥 | 氨氯地平、阿利可仑和氢氯噻嗪复方降压药物 |
| CN102626391B (zh) * | 2012-04-19 | 2013-07-10 | 海南美兰史克制药有限公司 | 一种阿利克仑氢氯噻嗪药物组合物脂质体固体制剂 |
| GB201317373D0 (en) | 2013-10-01 | 2013-11-13 | Univ Dundee | Treatment and prevention of cancer |
| CN111789843A (zh) * | 2019-04-08 | 2020-10-20 | 深圳奥萨医药有限公司 | 含氨氯地平、氯噻酮和阿米洛利的药物组合物 |
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| US5350771A (en) * | 1989-03-22 | 1994-09-27 | Peter K. T. Pang | Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers |
| AU656551B2 (en) * | 1990-12-14 | 1995-02-09 | Smithkline Beecham Corporation | Angiotensin II receptor blocking compositions |
| US5656650A (en) * | 1990-12-14 | 1997-08-12 | Smithkline Beecham Corp. | Angiotensin II receptor blocking compositions |
| US5178877A (en) * | 1991-01-04 | 1993-01-12 | Abbott Laboratories | Encapsulated renin inhibitor composition |
| US5114925A (en) * | 1991-01-22 | 1992-05-19 | Merck & Co., Inc. | Renin inhibitors containing the 2-[[(2R,3S)-3-amino-4-cyclohexyl-2-hydroxy-1-butyl]thio)alkanoyl moiety and the corresponding sulfoxide and sulfone derivatives |
| US5256667A (en) * | 1991-09-25 | 1993-10-26 | Merck & Co., Inc. | Quinazolinones and pyridopyrimidinones |
| US5202322A (en) * | 1991-09-25 | 1993-04-13 | Merck & Co., Inc. | Quinazolinone and pyridopyrimidine a-II antagonists |
| US5292741A (en) * | 1992-08-18 | 1994-03-08 | Merck & Co., Inc. | Macrocycles incorporating quinazolinones |
| MY119161A (en) | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| EP0795327A1 (en) * | 1996-03-13 | 1997-09-17 | Pfizer Inc. | Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| US20040087484A1 (en) * | 2000-12-01 | 2004-05-06 | Sahota Pritam Singh | Combination of organic compounds |
| EP1426051B1 (en) * | 2001-09-11 | 2008-07-16 | Asahi Kasei Pharma Corporation | Medicinal composition for prevention of or treatment for cerebrovascular disorder |
| US7019010B2 (en) * | 2001-09-27 | 2006-03-28 | Novertis Ag | Combinations |
| DK1507558T3 (da) * | 2002-05-17 | 2011-12-05 | Novartis Pharma Ag | Farmaceutisk sammensætning omfattende en renininhibitor, en calciumkanalblokker og et diuretikum |
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2003
- 2003-05-16 DK DK03730064.7T patent/DK1507558T3/da active
- 2003-05-16 ES ES03730064T patent/ES2369216T3/es not_active Expired - Lifetime
- 2003-05-16 EP EP03730064A patent/EP1507558B8/en not_active Expired - Lifetime
- 2003-05-16 MX MXPA04011383A patent/MXPA04011383A/es active IP Right Grant
- 2003-05-16 AT AT03730064T patent/ATE520417T1/de active
- 2003-05-16 RU RU2004137104/15A patent/RU2316318C2/ru not_active IP Right Cessation
- 2003-05-16 EP EP10177741A patent/EP2316488A1/en not_active Withdrawn
- 2003-05-16 AU AU2003240669A patent/AU2003240669B2/en not_active Ceased
- 2003-05-16 KR KR10-2004-7018479A patent/KR20050008717A/ko not_active Ceased
- 2003-05-16 WO PCT/EP2003/005188 patent/WO2003097098A1/en not_active Ceased
- 2003-05-16 NZ NZ536555A patent/NZ536555A/en not_active IP Right Cessation
- 2003-05-16 KR KR1020107028689A patent/KR20100137026A/ko not_active Ceased
- 2003-05-16 US US10/514,683 patent/US20050182042A1/en not_active Abandoned
- 2003-05-16 BR BR0310084-7A patent/BR0310084A/pt not_active Application Discontinuation
- 2003-05-16 SI SI200332071T patent/SI1507558T1/sl unknown
- 2003-05-16 CA CA2485081A patent/CA2485081C/en not_active Expired - Fee Related
- 2003-05-16 JP JP2004505094A patent/JP5288678B2/ja not_active Expired - Fee Related
- 2003-05-16 PT PT03730064T patent/PT1507558E/pt unknown
- 2003-05-16 KR KR1020137023159A patent/KR20130109244A/ko not_active Ceased
- 2003-05-16 CN CNA03811237XA patent/CN1655819A/zh active Pending
- 2003-05-16 PL PL372203A patent/PL219032B1/pl unknown
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2004
- 2004-10-19 ZA ZA200408442A patent/ZA200408442B/en unknown
- 2004-10-25 IL IL164837A patent/IL164837A/en not_active IP Right Cessation
- 2004-11-12 EC EC2004005428A patent/ECSP045428A/es unknown
- 2004-12-15 NO NO20045459A patent/NO334382B1/no not_active IP Right Cessation
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2008
- 2008-08-08 US US12/188,604 patent/US8183295B2/en not_active Expired - Fee Related
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2010
- 2010-08-13 JP JP2010181380A patent/JP2010280708A/ja not_active Withdrawn
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2011
- 2011-11-07 CY CY20111101071T patent/CY1112013T1/el unknown
- 2011-11-30 US US13/307,567 patent/US20120071470A1/en not_active Abandoned
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2012
- 2012-05-14 CY CY2012011C patent/CY2012011I2/el unknown
- 2012-05-14 LU LU92000C patent/LU92000I2/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210149498A (ko) * | 2020-06-02 | 2021-12-09 | 이화여자대학교 산학협력단 | 플루나리진 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 |
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