KR20030035335A - Hair-care composition containing porifera extract - Google Patents

Abstract

PURPOSE: Provided is a hair-care composition containing a Porifera extract which inhibits the growth and activity of Pityrosporum ovale, suppresses itch of scalp, maximizes moisture absorption to hair and prevent hair from being damaged. CONSTITUTION: A hair-care composition is characterized by comprising 0.01-20 wt.% of a Porifera extract based on total weight of the composition. It further comprises zinc pyrithione or pyroctone olamine. Therefore, it has prevention and treatment effects on dandruff.

Description

Hair-Care composition containing Porifera extract

The present invention relates to a hair cosmetic composition, and more particularly to a hair cosmetic composition that can impart moisture to the hair while preventing and treating dandruff.

Dandruff is a mild form of scalp seborrheic dermatitis, which is another term for dry seborrhea, and can be defined as a scaly non-inflammatory physiological substance that is excessively secreted from the scalp. It can occur in seborrhea in both men and women after puberty.

There are many causes of dandruff, including the effects of androgen hormones, genetic factors, food, fungi, and mental strain. Recently, stress has been the main cause. Therefore, a lot of dandruff occurs in modern people who are exposed to various stresses.

The causative agent of dandruff is the Pityrosporum ovale yeast group that resides on the skin such as scalp. If the bacteria are abnormally high, exceeding 74% of the normal flora, dandruff occurs, and if it is higher than 83%, seborrheic dermatitis develops.

In addition, Pytiros Forum Ovale is one of the normal scalp bacteria and remains around the sebaceous gland-rich hair, and it causes dandruff symptoms such as swelling and itching by hyperproliferation and causes seborrheic dermatitis in severe hyperplasia {MGGinley, KJ, et al. .: J. Invest. Dermatol. 64, 40 (1975)}.

Therefore, in the case of hair cosmetics having a dandruff inhibitory effect for the purpose of treating and preventing dandruff and itching, it effectively inhibits the growth and activity of the microbial Pytilosforum obale, which is the main cause of dandruff, and prevents abnormal metabolic activity of scalp cells. It is essential to contain a component that can be normalized.

As such, hair cosmetic compositions aimed at suppressing dandruff and itching have been mainly used as ketoconazole, zinc pyrithion, and the like, which are antifungal agents for inhibiting excessive proliferation of Pytiros forum obale. Tar, sulfur, and salicylic acid have been used to relieve itching and tearing, and selenium sulfide and zinc pyrithione have been used to suppress epidermal hyperproliferation.

Representative examples of such a cosmetic composition for hair is a hair cosmetic material containing a zinc pyrithione-polycternium complex (patent application No. 1999-048341), anti-dandruff hair products (patent application No. 1997-009838), containing the creation extract Hair product composition (patent application No. 1997-022750), anti-dandruff shampoo composition (patent application No. 1999-035791), anti-dandruff hair ingredient (patent application No. 1996-026222), tea tree oil Anti-dandruff cosmetics (Patent Application No. 1996-062053), Water-soluble shale oil (頁岩 油) containing dandruff inhibitory effect (Patent Application No. 1996-036114), Shampoo composition containing ginkgo leaf extract (Patent application No. 1991- 025848), dandruff treatment composition (patent application No. 1997-010124), and the like.

However, while the antifungal agents that have been used for dandruff treatment have a good effect on dandruff treatment, most of them are artificially synthesized, which raises questions about human safety. Causing damage (Gene A. Hyde and Mark M. Auerbach, Formulation Techniques for Zinc Pyrithione Antidandruff Shampoos, Cosmetics and Toileties, Vol. 94, P.57, April 1979; Patent Application No. 1997-022750).

Sea sponges (porifera) belong to the lower inferior animal species of the welfare animals, also called sponges, and are considered as animals that developed along the sideways in the process of evolution from protozoa to welfare animals. Also called). These sea levels are distributed in deep seas with a depth of 10 to 9,000 meters, and are sometimes attached to shells such as sea urchins and shellfish, and some are standing on mud bottoms. In addition, sponges live on rocks or on the ground without movement, so they are easy to think of as plants, but they feed through small and large holes. The current species has a variety of shapes and colors, and around 10,000 species are known all over the world.Because Spongia is a fiber skeleton, it bleaches itself and is mainly used for clothing, toiletries, cleaning products, and furniture. Recently, many studies have been conducted to derive anticancer active substances from these sponges (KOSEF No: 971-0711-093-2), but there is no example of use as a cosmetic composition for hair.

In order to solve the above problems, the present inventors have studied to provide a cosmetic composition for hair containing a natural physiologically active substance that does not cause a problem of safety by hypoallergenic to the human body, and can enhance the dandruff inhibitory effect and hair moisture retention. While performing the seawater extract, which is a natural marine organism, was found to be excellent in antifungal power and hair moisture retention ability against Pytiros forum obale bacteria, thereby completing the present invention.

Therefore, the present invention is not only excellent in preventing and treating dandruff by containing a sponge extract as an active ingredient that strongly inhibits the growth of phytirosporum obale, a causative agent of dandruff in the scalp, but also prevents roughening of hair. An object of the present invention is to provide a hair cosmetic composition having an effect of imparting moisture to hair.

The present invention for achieving the above object relates to a hair cosmetic composition containing 0.01 to 20% by weight of the sponge extract based on the total weight of the composition.

The hair cosmetic material composition may further include zinc pyrithione or pyrotonolamine.

Hereinafter, the present invention will be described in detail.

In the present invention, any material can be used as a material for obtaining the sponge extract, but it is preferable to use about 10 kinds of sponges collected from the region of the coastal seas of Korea (Tadohaehaesang National Park).

Sea sponges collected at a depth of 10 to 30 meters are dried appropriately and ground to a size of about 50 mesh.

The ground sponges are extracted by chilling for 5-7 days in an extraction solvent weighing about 10 times. At this time, the extraction solvent is preferably used by mixing one or two or more selected from methanol, acetone, ethyl acetate, benzene, hexane, diethyl ether, ethanol, propylene glycol, 1,3-butylene glycol, methyl chloride. .

The extracted crude solution is filtered in a conventional manner, concentrated to remove the solvent to obtain a sponge sponge concentrate. The sponge extract is obtained by diluting the obtained sponge concentrate with a solvent. When diluting, the solvent may be selected from the same materials as those used as the extraction solvent, and it is particularly preferable to use 1,3-butylene glycol. In addition, the sponge concentration and the solvent is preferably mixed in a weight ratio of 1: 1.

In the present invention, the sponge extract is added to a conventional hair cosmetic composition, 0.01 to 20% by weight based on the total weight of the composition to prepare a hair cosmetic composition. If the sponge extract is used at less than 0.01% by weight, there is no effect, and even if it is used in excess of 20% by weight, the effect is not particularly enhanced, so it is preferable to add 0.01 to 20% by weight. Particular preference is given to adding 0.5 to 5% by weight.

The sponge extract as described above may be used alone or in combination with a known anti-dandruff component such as zinc pyrithione and pyroxtonolamine, and further enhanced by using such a known anti-dandruff component.

The hair cosmetic composition of the present invention as described above may be used in the form of a shampoo, hair conditioner, hair tonic and the like.

The present invention will be described in more detail with reference to the following Examples. However, the following examples are intended to illustrate the present invention and do not limit the scope of the present invention.

(Example 1)

100 g of sea sponges were dried and pulverized to about 50 mesh, which was immersed in about 10 times the extraction solvent for 7 days and treated with ultra-high frequency of 40 kHz on the 7th day for 6 hours.

After ultra-high frequency treatment, the resultant was filtered using filter paper (Wattman No. 1: 11 μm), and the solvent was evaporated while heating at 60 ° C. under a reduced pressure of 0.6-0.8 kgf / cm 2 to obtain 3 g of sponge concentrate.

The obtained sponge concentrate was mixed with 3 g of 1,3-butylene glycol to obtain a sponge extract.

(Example 2-5 and Comparative Example 1-2)

To prepare a shampoo of the general formulation according to the composition ratio as shown in Table 1.

Tables 1 to 5, and 14 of Table 1 were uniformly mixed and dissolved at 60 ° C, and then cooled to 40 ° C, and then mixed with 6 to 13 ingredients to the mixture, followed by cooling to room temperature and shampoo type. The formulation was prepared.

Optional ingredients used in the compositions of the present invention are known in the art as conventional optional ingredients used to maintain basic physical properties and qualities.

Unit: weight% number ingredient Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 One Sodium Lauryl Sulfate (30%) 20.0 20.0 20.0 20.0 20.0 20.0 2 Sodium polyoxyethylene lauryl sulfate (30%) 20.0 20.0 20.0 20.0 20.0 20.0 3 Palm oil fatty acid diethanolamide 3.0 3.0 3.0 3.0 3.0 3.0 4 Propylene glycol 1.5 1.5 1.5 1.5 1.5 1.5 5 Cocamidopropyl Betaine 5.0 5.0 5.0 5.0 5.0 5.0 6 Pyrotonolamine - - 0.5 - 0.5 - 7 Zinc pyrithione - - - 0.5 - 0.5 8 Sponge extract 0.5 5.0 2.0 1.0 - - 9 Citric acid 0.3 0.3 0.3 0.3 0.3 0.3 10 Pigment Quantity Quantity Quantity Quantity Quantity Quantity 11 Methylparahydroxybenzoate 0.2 0.2 0.2 0.2 0.2 0.2 12 Hydrolyzed Silk 0.5 0.5 0.5 0.5 0.5 0.5 13 Spices Quantity Quantity Quantity Quantity Quantity Quantity 14 Purified water Make the sum total 100

Experimental Example 1

Antimicrobial activity comparison experiment

A paper disc test was performed on the shampoo-type preparations obtained in Examples 2-5 and Comparative Examples 1-2 to confirm the antimicrobial activity against the causative agent of dandruff.

First, in order to activate the test strain Pytirose forum Ovalle (ATCC 12087) was pre-cultured for 5 days in Potato dextrose broth (containing 1% corn oil) medium. The culture medium thus prepared was plated on a solid medium (potato dextrose broth + 1.5% agar) and dried.

A 50% aqueous solution of the shampoo formulations prepared in Examples 2-5 and Comparative Examples 1-2 was dropped in 40 μl each on a 8 mm diameter paper disk, and then placed on a solid medium prepared above, and incubated in a 30 ° C. incubator for 3 days.

After incubation for 3 days, the antimicrobial activity was evaluated by observing the bacterial growth inhibition area around the paper disk and measuring the growth ring size of the bacterial growth. The results are shown in Table 2 below.

Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Size of germ growth resistant ring (mm) 2.1 5.2 5.2 4.0 1.3 1.2

As can be seen in Table 2, it can be seen that the formulation of Example 2-5 is superior to the growth inhibitory effect of dandruff compared to the formulation of Comparative Example 1-2.

Experimental Example 2

Affinity with hair (moisture retention test)

Twelve hair samples of about 3.0 g were made, washed, and spreaded to remove moisture sufficiently, dried in a 60 ° C. thermostat for 1 hour, and cooled in a silica gel desiccator to accurately measure hair weight.

After the measurement, two hair samples were sufficiently wetted in Example 2-5 and Comparative Example 1-2 each time, and after being emptied, they were washed with running water at 40 ° C for about 20 seconds, then spread to remove sufficient moisture and dried in a 60 ° C thermostat for 1 hour. .

Subsequently, the mixture was allowed to cool in a silica gel desiccator, and the weight of the hair was precisely measured, and the affinity with the hair was measured using the difference from the measured weight as the hair adsorption amount (%) of each sample.

Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Hair adsorption amount (%) 1.0 1.7 1.6 1.3 0.14 0.12

As can be seen in Table 3, the results of Example 2-5, which is a shampoo formulation containing the sponge extract, showed a good affinity with the hair, that is, the moisture adsorption amount of the hair itself, as compared with the formulation of the comparative example.

Experimental Example 3

Clinical trial on anti-dandruff effect

36 men aged 19-35 years with a lot of dandruff were selected and tested for six months in six groups of six for the shampoos of Example 2-5 and Comparative Example 1-2, and the results are shown in Table 4 below. .

Before the start of the experiment, the hair is usually triturated with a normal shampoo, and after 3 days, the accumulated dandruff is collected, and the weight of the collected dandruff and the hair cosmetic composition of Examples 2-5 and Comparative Examples 1-2 once every two days. For the amount of dandruff accumulated for 3 days after the end of the test, the dandruff reduction rate was compared and evaluated by the following equation. Dandruff collection on the scalp is detached by combing five times on each side three times using a hard rubber brush (full length 10.0cm × width 5.0cm) with a comb spacing of 2.5mm in a space without air flow. The amount of dandruff was taken.

Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Dandruff reduction rate (%) 25.7 35.3 33.3 28.1 5.5 4.6

Experimental Example 4

Itching elimination test

After selecting 32 men and women who feel itching as usual and divided into four groups of eight people, the samples of Examples 2 to 4 and Comparative Example 1 were used once every two days for eight weeks, and then interviewed according to the following evaluation criteria. Evaluated.

Evaluation standard

Very itchy (A) ..... 1 point

Slightly itchy (B) ... 2 points

Normal (C) ..... 3 points

Good (D) ..... 4 points

(E) ..... 5 points

Using the results evaluated in accordance with the evaluation criteria, itching effect was calculated according to the following formula, and the results are shown in Table 5.

Itching removal effect = [(A × number of people after use) + (B × number of people after use) + ···]-[(A × number of people before use) + (B × number of people before use) + ···]

Example 2 Example 3 Example 4 Comparative Example 1 Anti-itch effect 6.2 13.7 11.6 2.14

As shown in Table 5, the shampoo formulation of Examples 2 to 4 containing the sponge extract was superior to the itch prevention effect of the scalp than the shampoo formulation of Comparative Example 1.

As described above, the hair cosmetic composition containing the spongy extract of the present invention is a scalp flora and inhibits the growth and activity of the dandruff phytirosforum obale, which plays a direct role in the growth of dandruff, inhibits itching of the scalp, and moisture to the hair. The effect of preventing damage to the hair is excellent by increasing the amount of adsorption.

Claims (2)

Hair cosmetic composition, characterized in that it contains 0.01 to 20% by weight based on the total weight of the composition. The method of claim 1, Hair cosmetic composition, characterized in that the composition further comprises zinc pyrithione or pyrotonolamine.