KR20010105248A - 충실성 종양 치료용 약제를 제조하기 위한 알부민안정화된 파클리탁셀의 용도 및 이로부터 수득된 약제 - Google Patents

충실성 종양 치료용 약제를 제조하기 위한 알부민안정화된 파클리탁셀의 용도 및 이로부터 수득된 약제 Download PDF

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Publication number
KR20010105248A
KR20010105248A KR1020010026970A KR20010026970A KR20010105248A KR 20010105248 A KR20010105248 A KR 20010105248A KR 1020010026970 A KR1020010026970 A KR 1020010026970A KR 20010026970 A KR20010026970 A KR 20010026970A KR 20010105248 A KR20010105248 A KR 20010105248A
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KR
South Korea
Prior art keywords
paclitaxel
treatment
drug
physiological solution
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020010026970A
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English (en)
Korean (ko)
Inventor
팔치아니마르코
Original Assignee
에이씨에스 도브파 에스. 피. 에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11445079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20010105248(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 에이씨에스 도브파 에스. 피. 에이. filed Critical 에이씨에스 도브파 에스. 피. 에이.
Publication of KR20010105248A publication Critical patent/KR20010105248A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020010026970A 2000-05-18 2001-05-17 충실성 종양 치료용 약제를 제조하기 위한 알부민안정화된 파클리탁셀의 용도 및 이로부터 수득된 약제 Ceased KR20010105248A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI001107A ITMI20001107A1 (it) 2000-05-18 2000-05-18 Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel
ITMI2000A001107 2000-05-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020080094590A Division KR20080091747A (ko) 2000-05-18 2008-09-26 알부민 안정화된 파클리탁셀을 포함하는 고형성 종양 치료용 약물 제형

Publications (1)

Publication Number Publication Date
KR20010105248A true KR20010105248A (ko) 2001-11-28

Family

ID=11445079

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020010026970A Ceased KR20010105248A (ko) 2000-05-18 2001-05-17 충실성 종양 치료용 약제를 제조하기 위한 알부민안정화된 파클리탁셀의 용도 및 이로부터 수득된 약제
KR1020080094590A Ceased KR20080091747A (ko) 2000-05-18 2008-09-26 알부민 안정화된 파클리탁셀을 포함하는 고형성 종양 치료용 약물 제형

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020080094590A Ceased KR20080091747A (ko) 2000-05-18 2008-09-26 알부민 안정화된 파클리탁셀을 포함하는 고형성 종양 치료용 약물 제형

Country Status (22)

Country Link
US (1) US6652884B2 (https=)
EP (1) EP1155692B1 (https=)
JP (1) JP2001354559A (https=)
KR (2) KR20010105248A (https=)
CN (1) CN1198609C (https=)
AT (1) ATE267594T1 (https=)
AU (1) AU781517B2 (https=)
BR (1) BR0102040A (https=)
CA (1) CA2345482A1 (https=)
DE (1) DE60103453T2 (https=)
DK (1) DK1155692T3 (https=)
ES (1) ES2221874T3 (https=)
HU (1) HU229909B1 (https=)
IL (1) IL142674A0 (https=)
IT (1) ITMI20001107A1 (https=)
MX (1) MXPA01004980A (https=)
NO (1) NO330511B1 (https=)
NZ (1) NZ511201A (https=)
PT (1) PT1155692E (https=)
RU (1) RU2270003C2 (https=)
TR (1) TR200101353A3 (https=)
ZA (1) ZA200103755B (https=)

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ITMI20020681A1 (it) * 2002-03-29 2003-09-29 Acs Dobfar Spa Procedimento per la produzione di nanoparticelle di paclitaxel ed albumina
ITMI20020680A1 (it) * 2002-03-29 2003-09-29 Acs Dobfar Spa Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento
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CN1925874B (zh) * 2002-12-09 2014-12-17 阿布拉西斯生物科学有限责任公司 组合物和传递药剂的方法
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
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US20080280987A1 (en) * 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
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US20100166869A1 (en) * 2007-05-03 2010-07-01 Desai Neil P Methods and compositions for treating pulmonary hypertension
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KR101090505B1 (ko) * 2008-12-30 2011-12-06 최은아 난담반을 포함하는 암 예방 및 치료용 조성물
HRP20192259T1 (hr) 2009-04-15 2020-03-06 Abraxis Bioscience, Llc Pripravci nanočestica bez priona i metode njihove proizvodnje
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Also Published As

Publication number Publication date
ITMI20001107A1 (it) 2001-11-18
HU229909B1 (en) 2014-12-29
TR200101353A2 (tr) 2001-12-21
ZA200103755B (en) 2001-11-15
HUP0102039A3 (en) 2002-12-28
DE60103453T2 (de) 2005-06-23
NO20012409D0 (no) 2001-05-16
CN1198609C (zh) 2005-04-27
AU3876501A (en) 2001-11-22
KR20080091747A (ko) 2008-10-14
MXPA01004980A (es) 2002-08-06
IL142674A0 (en) 2002-03-10
HK1040368A1 (en) 2002-06-07
AU781517B2 (en) 2005-05-26
NO20012409L (no) 2001-11-19
ATE267594T1 (de) 2004-06-15
RU2270003C2 (ru) 2006-02-20
JP2001354559A (ja) 2001-12-25
ITMI20001107A0 (it) 2000-05-18
HU0102039D0 (en) 2001-07-30
PT1155692E (pt) 2004-09-30
CN1324613A (zh) 2001-12-05
BR0102040A (pt) 2002-03-19
DE60103453D1 (de) 2004-07-01
US20010046961A1 (en) 2001-11-29
NO330511B1 (no) 2011-05-09
ES2221874T3 (es) 2005-01-16
US6652884B2 (en) 2003-11-25
TR200101353A3 (tr) 2001-12-21
HUP0102039A2 (hu) 2002-05-29
CA2345482A1 (en) 2001-11-18
DK1155692T3 (da) 2004-08-09
NZ511201A (en) 2002-11-26
EP1155692A1 (en) 2001-11-21
EP1155692B1 (en) 2004-05-26

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