KR20010080402A - Ｃｒｆ 수용체 길항제 및 그와 관련된 방법 - Google Patents
Ｃｒｆ 수용체 길항제 및 그와 관련된 방법 Download PDFInfo
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- KR20010080402A KR20010080402A KR1020017005818A KR20017005818A KR20010080402A KR 20010080402 A KR20010080402 A KR 20010080402A KR 1020017005818 A KR1020017005818 A KR 1020017005818A KR 20017005818 A KR20017005818 A KR 20017005818A KR 20010080402 A KR20010080402 A KR 20010080402A
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- alkyl
- methyl
- ethyl
- compound according
- phenyl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/16—Peri-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19095898A | 1998-11-12 | 1998-11-12 | |
| US40074499A | 1999-09-21 | 1999-09-21 | |
| US09/190,958 | 1999-09-21 | ||
| US09/400,744 | 1999-09-21 | ||
| PCT/US1999/026984 WO2000027850A2 (en) | 1998-11-12 | 1999-11-12 | Crf receptor antagonists and methods relating thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20010080402A true KR20010080402A (ko) | 2001-08-22 |
Family
ID=26886600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020017005818A Ceased KR20010080402A (ko) | 1998-11-12 | 1999-11-12 | Ｃｒｆ 수용체 길항제 및 그와 관련된 방법 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6348466B1 (enExample) |
| EP (1) | EP1129096B1 (enExample) |
| JP (1) | JP2002529469A (enExample) |
| KR (1) | KR20010080402A (enExample) |
| CN (1) | CN1178941C (enExample) |
| AT (1) | ATE240958T1 (enExample) |
| AU (1) | AU755997B2 (enExample) |
| BR (1) | BR9915129A (enExample) |
| CA (1) | CA2349904A1 (enExample) |
| DE (1) | DE69908173T2 (enExample) |
| DK (1) | DK1129096T3 (enExample) |
| ES (1) | ES2196898T3 (enExample) |
| HK (1) | HK1038925B (enExample) |
| IL (1) | IL143105A0 (enExample) |
| NO (1) | NO20012228D0 (enExample) |
| NZ (1) | NZ511267A (enExample) |
| PT (1) | PT1129096E (enExample) |
| TR (1) | TR200102178T2 (enExample) |
| WO (1) | WO2000027850A2 (enExample) |
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| EP1293213A1 (en) * | 2000-02-14 | 2003-03-19 | Japan Tobacco Inc. | Preventives/remedies for postoperative stress |
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| JP2003533526A (ja) | 2000-05-18 | 2003-11-11 | ニューロクライン バイオサイエンシーズ， インコーポレイテッド | Ｃｒｆレセプターアンタゴニストおよびそれに関連する方法 |
| US6541469B2 (en) | 2000-05-18 | 2003-04-01 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| US6747034B2 (en) * | 2000-11-03 | 2004-06-08 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| EP1354884B1 (en) | 2000-12-28 | 2007-10-10 | Ono Pharmaceutical Co., Ltd. | Cyclopenta[d]pyrazolo[1,5-a]pyrimidine compound as crf receptor antagonist |
| US6583143B2 (en) | 2000-12-28 | 2003-06-24 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| ATE320254T1 (de) * | 2001-04-30 | 2006-04-15 | Glaxo Group Ltd | Crf receptor antagonisten |
| GB0117395D0 (en) * | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
| US7273871B2 (en) | 2001-07-17 | 2007-09-25 | Sb Pharmco Puerto Rico Inc. | Phenyl-5,6,6A,7,8,9-hexahydro-4H-1,4,9-triaza-phenalene derivatives as CRF antagonists |
| DE602004028820D1 (de) | 2003-06-25 | 2010-10-07 | Ono Pharmaceutical Co | Methansulfonsäuresalz einer pyrazolopyrimidinverbindung, kristall davon und verfahren zu deren herstellung |
| US20060024661A1 (en) * | 2003-07-30 | 2006-02-02 | The Regents Of The University Of California | Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2 |
| JP2007515473A (ja) * | 2003-12-22 | 2007-06-14 | エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド | Ｃｒｆ受容体アンタゴニストおよびそれらに関連する方法 |
| CN101133157A (zh) | 2004-06-03 | 2008-02-27 | 阿什洛米克斯控股有限公司 | 诊断应激的药物和方法 |
| US7869958B2 (en) * | 2004-08-09 | 2011-01-11 | Research Development Foundation | Structure-based modulators of B1 G-protein coupled receptors |
| EP2433633A1 (en) | 2004-08-25 | 2012-03-28 | Ardea Biosciences, Inc. | Triazolyl alpha -mercaptoacetanildes as inhibitors of HIV reverse transcriptase |
| WO2007050087A1 (en) | 2004-08-25 | 2007-05-03 | Ardea Biosciences, Inc. | N[S(4-aryl-triazol-3-yl)α -mercaptoacetyl]-p-amino benozoic acids AS HIV REVERSE TRANSCRIPTASE INHIBITORS |
| ES2380951T3 (es) | 2005-05-05 | 2012-05-21 | Ardea Biosciences, Inc. | Diaril-purinas, -azapurinasy - desazapurinas como inhibidores no nucleósidos de la transcriptasa inversa para el tratamiento del VIH |
| US7595324B2 (en) | 2006-11-09 | 2009-09-29 | Ardea Biosciences, Inc. | Substituted thieno[3,2-D]pyrimidines as HIV inhibitors |
| MX2010005776A (es) | 2007-11-27 | 2010-08-31 | Ardea Biosciences Inc | Nuevos compuestos y composiciones y metodos de uso. |
| WO2009079412A2 (en) | 2007-12-14 | 2009-06-25 | Ardea Biosciences Inc. | Reverse transcriptase inhibitors |
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| US4605642A (en) | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| US5013737A (en) * | 1988-02-22 | 1991-05-07 | American Cyanamid Company | 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones |
| US4904658A (en) | 1988-04-15 | 1990-02-27 | American Cyanamid Company | Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones |
| US5063245A (en) | 1990-03-28 | 1991-11-05 | Nova Pharmaceutical Corporation | Corticotropin-releasing factor antagonism compounds |
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| ES2128544T3 (es) * | 1992-12-17 | 1999-05-16 | Pfizer | Pirrolopirimidinas como antagonistas del crf. |
| WO1995010506A1 (en) | 1993-10-12 | 1995-04-20 | The Du Pont Merck Pharmaceutical Company | 1n-alkyl-n-arylpyrimidinamines and derivatives thereof |
| TW574214B (en) | 1994-06-08 | 2004-02-01 | Pfizer | Corticotropin releasing factor antagonists |
| HU219911B (hu) | 1994-06-16 | 2001-09-28 | Pfizer Inc. | Pirazolo-piridin-származékok, alkalmazásuk és ezeket tartalmazó gyógyászati készítmények |
| AU716993B2 (en) | 1995-05-12 | 2000-03-16 | Neurogen Corporation | Novel deazapurine derivatives; a new class of CRF1 specific ligands |
| FR2735777B1 (fr) | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| JP2000507552A (ja) | 1996-03-26 | 2000-06-20 | デュポン ファーマシューティカルズ カンパニー | アリールオキシおよびアリールチオ縮合ピリジン、アリールオキシおよびアリールチオ縮合ピリミジン、およびそれらの誘導体 |
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| ES2294800T3 (es) | 1996-07-24 | 2008-04-01 | Bristol-Myers Squibb Pharma Company | Azolo triazinas y pirimidinas. |
| AU709203B2 (en) | 1996-08-06 | 1999-08-26 | Pfizer Inc. | Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives |
| TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| BR9711970A (pt) * | 1996-08-28 | 1999-08-24 | Pfizer | Derivados 6,5-substitu¡do-heterobic¡clicos |
| ATE213495T1 (de) | 1996-09-16 | 2002-03-15 | Du Pont Pharm Co | Eine resorbierbare röntgenopake markierung enthaltendes chirurgisches implantat und verfahren zum verriegeln desselben in einem körper |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| US5760225A (en) | 1996-11-15 | 1998-06-02 | Neurogen Corporation | Certain pyrazole derivatives as corticotropin-releasing factor receptor CRF1 specific ligands |
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-
1999
- 1999-11-12 BR BR9915129-4A patent/BR9915129A/pt not_active IP Right Cessation
- 1999-11-12 CA CA002349904A patent/CA2349904A1/en not_active Abandoned
- 1999-11-12 PT PT99961675T patent/PT1129096E/pt unknown
- 1999-11-12 WO PCT/US1999/026984 patent/WO2000027850A2/en not_active Ceased
- 1999-11-12 IL IL14310599A patent/IL143105A0/xx unknown
- 1999-11-12 ES ES99961675T patent/ES2196898T3/es not_active Expired - Lifetime
- 1999-11-12 JP JP2000581028A patent/JP2002529469A/ja active Pending
- 1999-11-12 TR TR2001/02178T patent/TR200102178T2/xx unknown
- 1999-11-12 CN CNB998131725A patent/CN1178941C/zh not_active Expired - Fee Related
- 1999-11-12 AU AU18199/00A patent/AU755997B2/en not_active Ceased
- 1999-11-12 US US09/439,841 patent/US6348466B1/en not_active Expired - Fee Related
- 1999-11-12 DE DE69908173T patent/DE69908173T2/de not_active Expired - Lifetime
- 1999-11-12 KR KR1020017005818A patent/KR20010080402A/ko not_active Ceased
- 1999-11-12 NZ NZ511267A patent/NZ511267A/xx unknown
- 1999-11-12 DK DK99961675T patent/DK1129096T3/da active
- 1999-11-12 EP EP99961675A patent/EP1129096B1/en not_active Expired - Lifetime
- 1999-11-12 AT AT99961675T patent/ATE240958T1/de not_active IP Right Cessation
- 1999-11-12 HK HK02100689.4A patent/HK1038925B/en not_active IP Right Cessation
-
2001
- 2001-05-04 NO NO20012228A patent/NO20012228D0/no not_active Application Discontinuation
- 2001-12-20 US US10/027,789 patent/US6723721B2/en not_active Expired - Lifetime
-
2004
- 2004-02-23 US US10/785,386 patent/US20040229879A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU755997B2 (en) | 2003-01-02 |
| DE69908173D1 (de) | 2003-06-26 |
| CA2349904A1 (en) | 2000-05-18 |
| NO20012228L (no) | 2001-05-04 |
| CN1326458A (zh) | 2001-12-12 |
| EP1129096B1 (en) | 2003-05-21 |
| WO2000027850A3 (en) | 2000-08-03 |
| WO2000027850A2 (en) | 2000-05-18 |
| DE69908173T2 (de) | 2004-08-19 |
| CN1178941C (zh) | 2004-12-08 |
| US6723721B2 (en) | 2004-04-20 |
| NZ511267A (en) | 2002-12-20 |
| ES2196898T3 (es) | 2003-12-16 |
| US20020143008A1 (en) | 2002-10-03 |
| HK1038925A1 (en) | 2002-04-04 |
| NO20012228D0 (no) | 2001-05-04 |
| HK1038925B (en) | 2003-12-05 |
| ATE240958T1 (de) | 2003-06-15 |
| DK1129096T3 (da) | 2003-09-15 |
| IL143105A0 (en) | 2002-04-21 |
| EP1129096A2 (en) | 2001-09-05 |
| US20040229879A1 (en) | 2004-11-18 |
| AU1819900A (en) | 2000-05-29 |
| US6348466B1 (en) | 2002-02-19 |
| BR9915129A (pt) | 2001-08-07 |
| PT1129096E (pt) | 2003-09-30 |
| TR200102178T2 (tr) | 2002-01-21 |
| JP2002529469A (ja) | 2002-09-10 |
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