KR20010041625A - 신규 용도 - Google Patents

신규 용도 Download PDF

Info

Publication number
KR20010041625A
KR20010041625A KR1020007009824A KR20007009824A KR20010041625A KR 20010041625 A KR20010041625 A KR 20010041625A KR 1020007009824 A KR1020007009824 A KR 1020007009824A KR 20007009824 A KR20007009824 A KR 20007009824A KR 20010041625 A KR20010041625 A KR 20010041625A
Authority
KR
South Korea
Prior art keywords
dione
indole
group
phenyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020007009824A
Other languages
English (en)
Korean (ko)
Inventor
자나키라만 라마찬드란
Original Assignee
아스트라제네카 악티에볼라그
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9801370A external-priority patent/SE9801370D0/xx
Application filed by 아스트라제네카 악티에볼라그 filed Critical 아스트라제네카 악티에볼라그
Publication of KR20010041625A publication Critical patent/KR20010041625A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020007009824A 1998-03-06 1999-03-04 신규 용도 Ceased KR20010041625A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN46498 1998-03-06
IN464MA1998 1998-03-06
SE98013709 1998-04-20
SE9801370A SE9801370D0 (sv) 1998-04-20 1998-04-20 New use
PCT/SE1999/000319 WO1999044608A1 (en) 1998-03-06 1999-03-04 New use

Publications (1)

Publication Number Publication Date
KR20010041625A true KR20010041625A (ko) 2001-05-25

Family

ID=26324794

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007009824A Ceased KR20010041625A (ko) 1998-03-06 1999-03-04 신규 용도

Country Status (13)

Country Link
US (1) US6906090B1 (enExample)
EP (1) EP1058548B1 (enExample)
JP (1) JP2002505286A (enExample)
KR (1) KR20010041625A (enExample)
CN (1) CN100391455C (enExample)
AT (1) ATE249828T1 (enExample)
AU (1) AU735381B2 (enExample)
BR (1) BR9908510A (enExample)
CA (1) CA2320757A1 (enExample)
DE (1) DE69911380T2 (enExample)
NO (1) NO20004419L (enExample)
NZ (1) NZ506217A (enExample)
WO (1) WO1999044608A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
US6399593B1 (en) 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6372752B1 (en) * 2000-02-07 2002-04-16 Genzyme Corporation Inha inhibitors and methods of use thereof
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
CN101863823B (zh) * 2010-06-03 2012-02-08 山东大学 吲哚二酮类化合物及其扩环衍生物、制备方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR65270B (en) * 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof
IE69677B1 (en) 1989-12-11 1996-10-02 Neurosearch As Isatine derivatives their preparation and use
US5164404A (en) 1991-03-15 1992-11-17 Neurosearch A/S Hydrazone derivatives and their use
SE9103752D0 (sv) 1991-12-18 1991-12-18 Astra Ab New compounds
US5206366A (en) * 1992-08-26 1993-04-27 Pfizer Inc. Process for preparing aryl piperazinyl-heterocyclic compounds
US5270331A (en) * 1993-01-26 1993-12-14 Pfizer, Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
SE9302080D0 (sv) * 1993-06-16 1993-06-16 Ab Astra New compounds

Also Published As

Publication number Publication date
HK1030885A1 (en) 2001-05-25
EP1058548A1 (en) 2000-12-13
WO1999044608A1 (en) 1999-09-10
DE69911380T2 (de) 2004-07-01
JP2002505286A (ja) 2002-02-19
CN100391455C (zh) 2008-06-04
AU735381B2 (en) 2001-07-05
WO1999044608A8 (en) 2005-01-06
AU2757399A (en) 1999-09-20
NZ506217A (en) 2002-05-31
NO20004419L (no) 2000-10-20
ATE249828T1 (de) 2003-10-15
NO20004419D0 (no) 2000-09-05
CA2320757A1 (en) 1999-09-10
DE69911380D1 (de) 2003-10-23
BR9908510A (pt) 2000-11-21
CN1292694A (zh) 2001-04-25
US6906090B1 (en) 2005-06-14
EP1058548B1 (en) 2003-09-17

Similar Documents

Publication Publication Date Title
KR20010041625A (ko) 신규 용도
JP4095676B2 (ja) 注意障害を治療するためのコリンエステラーゼ阻害剤の使用
ES2306146T3 (es) Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a farmacos.
JP2650045B2 (ja) 新規な抗抑欝剤
RU2560676C2 (ru) Противотуберкулезная композиция, содержащая соединения оксазола
EP0639976B1 (en) Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
CA2345406A1 (en) Analgesic
HUP0400833A2 (hu) Benzo[g]kinolin-származékok glaukoma és miopia kezelésére, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
US20050256128A1 (en) Antimycobacterial pharmaceutical composition
EP0543855A1 (en) Use of aryl hydroxyurea compounds for the treatment of atherosclerosis
KR20010043322A (ko) 미코박테리아성 억제제
KR101754516B1 (ko) 페난트레닐계 화합물 또는 이의 유도체, 및 이를 함유하는 결핵 치료용 약학조성물
US3629418A (en) Process for producing an anti-depressant effect with piperazine quinolines
MXPA00008457A (en) New use
HK1030885B (en) The use of isatin and oxindole derivatives in the preparation of a medicament for use in the treatment of mycobacterial disease
CN108440446A (zh) 含有肟基片段的苯并噻嗪-4-酮类化合物及其制备方法
CN101863876A (zh) 有7-(3-氨基-4-肟基)-1-哌啶基取代基的氟喹诺酮及其组合物的应用
AU2013203952A1 (en) Antituberculous composition comprising oxazole compounds
JPH0597673A (ja) 抗不整脈薬
JPS63287725A (ja) 向知性薬
JPH10109936A (ja) 糖尿病性神経障害の治療・予防剤
HK1177427A (en) Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
JPH04202191A (ja) ピペラジン誘導体及びこれを含有するｎｍｄａ受容体拮抗剤

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20000905

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20040304

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20051024

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20060404

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20051024

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I