ATE249828T1 - Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungen - Google Patents
Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungenInfo
- Publication number
- ATE249828T1 ATE249828T1 AT99908059T AT99908059T ATE249828T1 AT E249828 T1 ATE249828 T1 AT E249828T1 AT 99908059 T AT99908059 T AT 99908059T AT 99908059 T AT99908059 T AT 99908059T AT E249828 T1 ATE249828 T1 AT E249828T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- isatin
- production
- medicinal products
- mycobacterial diseases
- Prior art date
Links
- JXDYKVIHCLTXOP-UHFFFAOYSA-N isatin Chemical compound C1=CC=C2C(=O)C(=O)NC2=C1 JXDYKVIHCLTXOP-UHFFFAOYSA-N 0.000 title abstract 4
- 208000027531 mycobacterial infectious disease Diseases 0.000 title abstract 2
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000005623 oxindoles Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN464MA1998 | 1998-03-06 | ||
| SE9801370A SE9801370D0 (sv) | 1998-04-20 | 1998-04-20 | New use |
| PCT/SE1999/000319 WO1999044608A1 (en) | 1998-03-06 | 1999-03-04 | New use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE249828T1 true ATE249828T1 (de) | 2003-10-15 |
Family
ID=26324794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99908059T ATE249828T1 (de) | 1998-03-06 | 1999-03-04 | Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6906090B1 (enExample) |
| EP (1) | EP1058548B1 (enExample) |
| JP (1) | JP2002505286A (enExample) |
| KR (1) | KR20010041625A (enExample) |
| CN (1) | CN100391455C (enExample) |
| AT (1) | ATE249828T1 (enExample) |
| AU (1) | AU735381B2 (enExample) |
| BR (1) | BR9908510A (enExample) |
| CA (1) | CA2320757A1 (enExample) |
| DE (1) | DE69911380T2 (enExample) |
| NO (1) | NO20004419L (enExample) |
| NZ (1) | NZ506217A (enExample) |
| WO (1) | WO1999044608A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
| US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
| US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
| US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
| US6319912B1 (en) | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
| US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
| US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
| US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6355648B1 (en) | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
| US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
| US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
| US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
| US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
| US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
| US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
| US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
| US6372752B1 (en) * | 2000-02-07 | 2002-04-16 | Genzyme Corporation | Inha inhibitors and methods of use thereof |
| UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| CN101863823B (zh) * | 2010-06-03 | 2012-02-08 | 山东大学 | 吲哚二酮类化合物及其扩环衍生物、制备方法及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR65270B (en) * | 1978-10-10 | 1980-07-31 | Fujisawa Pharmaceutical Co | Isatin derivatives and processes for the preparation thereof |
| IE69677B1 (en) | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
| US5164404A (en) | 1991-03-15 | 1992-11-17 | Neurosearch A/S | Hydrazone derivatives and their use |
| SE9103752D0 (sv) | 1991-12-18 | 1991-12-18 | Astra Ab | New compounds |
| US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
| US5270331A (en) * | 1993-01-26 | 1993-12-14 | Pfizer, Inc. | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides |
| SE9302080D0 (sv) * | 1993-06-16 | 1993-06-16 | Ab Astra | New compounds |
-
1999
- 1999-03-04 BR BR9908510-0A patent/BR9908510A/pt not_active Application Discontinuation
- 1999-03-04 AU AU27573/99A patent/AU735381B2/en not_active Ceased
- 1999-03-04 JP JP2000534210A patent/JP2002505286A/ja active Pending
- 1999-03-04 WO PCT/SE1999/000319 patent/WO1999044608A1/en not_active Ceased
- 1999-03-04 CA CA002320757A patent/CA2320757A1/en not_active Abandoned
- 1999-03-04 CN CNB998037249A patent/CN100391455C/zh not_active Expired - Fee Related
- 1999-03-04 AT AT99908059T patent/ATE249828T1/de not_active IP Right Cessation
- 1999-03-04 DE DE69911380T patent/DE69911380T2/de not_active Expired - Fee Related
- 1999-03-04 KR KR1020007009824A patent/KR20010041625A/ko not_active Ceased
- 1999-03-04 EP EP99908059A patent/EP1058548B1/en not_active Expired - Lifetime
- 1999-03-04 US US09/284,516 patent/US6906090B1/en not_active Expired - Fee Related
- 1999-03-04 NZ NZ506217A patent/NZ506217A/en unknown
-
2000
- 2000-09-05 NO NO20004419A patent/NO20004419L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1030885A1 (en) | 2001-05-25 |
| EP1058548A1 (en) | 2000-12-13 |
| WO1999044608A1 (en) | 1999-09-10 |
| DE69911380T2 (de) | 2004-07-01 |
| JP2002505286A (ja) | 2002-02-19 |
| CN100391455C (zh) | 2008-06-04 |
| AU735381B2 (en) | 2001-07-05 |
| WO1999044608A8 (en) | 2005-01-06 |
| AU2757399A (en) | 1999-09-20 |
| NZ506217A (en) | 2002-05-31 |
| NO20004419L (no) | 2000-10-20 |
| KR20010041625A (ko) | 2001-05-25 |
| NO20004419D0 (no) | 2000-09-05 |
| CA2320757A1 (en) | 1999-09-10 |
| DE69911380D1 (de) | 2003-10-23 |
| BR9908510A (pt) | 2000-11-21 |
| CN1292694A (zh) | 2001-04-25 |
| US6906090B1 (en) | 2005-06-14 |
| EP1058548B1 (en) | 2003-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69911380D1 (de) | Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungen | |
| ATE496624T1 (de) | Arzneimittel zur behandlung von osteonekrose und zur versorgung von patienten mit risiko für die entstehung von osteonekrose | |
| CY1107838T1 (el) | Παραγωγα αδαμαντανιου για τη θεραπεια φλεγμονωδων, ανοσολογικων και καρδιαγγειακων ασθενειων | |
| ATE252901T1 (de) | Arzneimittel zur behandlung von entzündlichen herzkrankheiten | |
| ATE455106T1 (de) | Acyl derivate zur behandlung von krankheiten die in zusammenhang mit vla-4 stehen | |
| ATE229815T1 (de) | In vitro methoden und verwendung von pharmazeutische zusammensetzungen für die behandlung von innenohrhaarzellen | |
| ATE284693T1 (de) | Verwendung von dopamin-d 3-rezeptorantagonisten zur herstellung von arzneimittel für die behandlung von nierenfunktionsstörungen | |
| ATE175114T1 (de) | Pharmazeutische zusammensetzungen enthaltend einen opiat antagonist und calcium salze, ihre verwendung zur behandlung von endorphin- vermittelten krankheiten | |
| DE69400435D1 (de) | Verwendung von carbamazepine und oxcarbazepine zur behandlung von parkinson und den parkinson-syndromen | |
| DE69810784D1 (de) | Verwendung von xanthophyllen zur herstellung von arzneimitteln zur verbesserung der muskel-funktionsdauer oder zur behandlung von muskelstörungen oder erkrankungen | |
| ATE263571T1 (de) | Verwendung von erythropoietin und eisenpräparaten zur herstellung von pharmazeutischen kombinationspräparaten zur behandlung von rheumatischen erkrankungen | |
| ATE350030T1 (de) | Nordihydroguaiaretinsäurederivate zur behandlung von tumoren | |
| DE69331605D1 (de) | Verwendung von phenserin zur herstellung von medikamenten zur behandlung von kognitiven störungen | |
| ATE218350T1 (de) | Verwendung von methanbisphosphonsäurederivaten zur behandlung von aufgelockerten prothesen | |
| ATE217197T1 (de) | Verwendung von hyaluronsäure und eines nsaid zur herstellung eines arzneimittels zur behandlung von krankheiten der mucosa | |
| DE69824576D1 (de) | Verwendung von tetrahydropyridinderivaten zur herstellung von arzneimitteln zur behandlung demyelinisierender erkrankungen | |
| ATE219670T1 (de) | Verwendung von arachidonsäure und/oder docohexaensäure zur herstellung eines arzneimittels zur behandlung von dyspraxia | |
| ATE252897T1 (de) | Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen | |
| DE69820480T2 (de) | Verwendung von wenigsten einem fukan zur herstellung eines arzneimittels für die behandlung pariodontaler erkrankungen | |
| BR0112807A (pt) | Derivados de indol e sua aplicação como medicamento | |
| ATE231849T1 (de) | Cyclopentabenzofuran-derivate und ihre verwendung | |
| TR200100637T2 (tr) | Yeni doğal ürün türevleri | |
| DE69130679D1 (de) | Die herstellung von zusammensetzungen zur behandlung von krankheiten der zellproliferation | |
| DE69805305D1 (de) | Verwendung von phanquinon zur behandlung von alzheimer's krankheit | |
| AU3862997A (en) | Stable derivatives of ubiquinole, processes for their production and pharmaceutical use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |