KR20010025970A - Propolis containing cleansing composition for ladies and process for preparing the same - Google Patents

Abstract

PURPOSE: A cleanser composition for women containing propolis is provided, which can be applied on skin easily, shows specific inhibiting or sterilizing activity to harmfulness bacillus and fungi in the vagina, shows also good odor-removing effect, helps degradation of fat on the surface of mucous membrane, and shows good cleansing activity without irritation. CONSTITUTION: A process for the preparation of cleanser composition for women containing propolis is comprised of: adding 99.9% ethanol to original propolis lump, and extracting propolis by leaving in the shade for 2days at 5deg.C; filtering with a Wattman paper, concentrating the filtrate using rotary vacuum distiller, adn distilling residual moisture in a desiccator to get the black-brown powdered propolis; dissolving in distilled water with perfume, cooling slowly, adjusting pH to be 3.5; meanwhile, pouring excessive quantity of water to green tea leaves to get tea extract, collecting supernatant, and distilling filtrate to get green tea extract; mixing the propolis and the green tea extract, adding distilled water, heating to 70deg.C, stirring for 30minutes using a Teflon magnetic stirrer, distilling water, drying in a desiccator, adding perfume, and making to be granules.

Description

Propolis-containing woman cleansing composition and its manufacturing method {PROPOLIS CONTAINING CLEANSING COMPOSITION FOR LADIES AND PROCESS FOR PREPARING THE SAME}

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a female detergent composition containing Propolis and a method for producing the same, and more particularly, to the plant's epidermis, especially shoots and buds, which are secreted by plants to protect them from harmful microorganisms. The present invention relates to a female vaginal and vulva cleaning composition comprising a propolis known as a natural antibiotic substance and a physiologically active substance produced by the reaction between sap and saliva of a bee, and a manufacturing method thereof.

Propolis is a variety of trees and herbs, such as pine, fir, willow, and rapeseed trees, that bees attach to the body hair to sap from the epidermis, flowers, buds, and buds to protect themselves from harmful microorganisms. It is a generic term for a complex of various polymers produced by mixing with their saliva and then reacting with enzymes in the saliva.

In nature, including beekeepers, bees use propolis to protect their honeycomb from cold and rainwater, and at the best humidity and temperature for the growth of various microorganisms such as bacteria, fungi and viruses (approximately). It is a bee called propolis that can work against diverse spectrum of microorganisms even though tens of thousands of people live under 32 ~ 35 ℃) and show strong vitality without killing the dense society by the onset of pathogenic microorganisms. It is believed to be due to its unique natural antibiotic and bioactive substances. The bees coat propolis on the entrance, gaps and inner walls of the honeycomb, but especially on the spawning site of the queen bee and the larvae's dwelling area, which can make eggs and larvae detrimental to harmful pathogenic microorganisms or residential environments. It is safe from microorganisms.

Propolis is B.C. Long ago 300 years ago, the ancient Egyptians used it effectively as an antiseptic to embalm mummies.These preservatives were used by moths, small rats, or snakes in the beehive, where they were killed by bees attack and then carried them out of the beehive. Failure to do so can also be seen from natural observations that the original form has been preserved without decay for years by propolis coated with bees. In addition to its efficacy as a preservative as described above for propolis, various papers and clinical reports by modern medicine suggest that propolis' anti-cancer, burn-healing, eczema, atopic dermatitis and athlete's foot are cured by skin fungi, such as athlete's foot, hair loss, etc. It has been reported to suppress and eliminate the pain of menstrual cramps, to remove constipation, skin care and wrinkles, and to cure and prevent bacterial dental diseases such as tooth decay, gingivitis and oral infections. It is defined as health supplement in 13-25.

In addition, flavonoids, one of the main components of propolis, are glycosides associated with sugars such as flavones, flavonones, flavonols, flavanols, flavanones, flavanols, and isoflavones, and glycosides thereof, and hundreds of anthocyanins and sugars. Its glycosides, combined with catechin and leucozancin as tannins, and flavonoids have a 5.6-fold boost in immunity from Dr. Kavarkina, Russia in 1969, and a stronger harmful bacterium than penicillin in Alexandria, Russia, in 1973. Announced proof of bactericidal test, analgesic and anti-inflammatory effect of Japan Biochemistry Association in 1991, clinical results of anticancer efficacy at Japan Polytechnic University in 1994, activation of other systemic cells, hormone stimulating activity, treatment of scurvy by action of vitamin P, hypertension Many countries in the world have excellent effects such as blood pressure lowering of patients and balance of biological hormones. The results of the study and the results of clinical trials are published.

On the other hand, the typical representative of women's cleaners include a surfactant with a cleaning power and povidone-iodine as a pharmaceutical ingredient, and the povidone-iodine, which is a disinfectant obtained by the above-described chemical synthesis, is used for Candida vaginitis, Trichomonas vaginitis and other texture inflammations. Although it is known to be effective in the prevention and treatment, it may cause hypersensitivity symptoms such as iodine, pruritus, burning sensation, skin ulcer, and contact dermatitis due to mucosal damage.In addition, an increase in intravaginal inorganic iodine or total blood iodine value causes hypothyroidism. It is known to cause.

Conventional techniques for eliminating the side effects caused by the use of disinfectants as medicines described above, in healthy women, the acidity of vaginal acid is maintained at pH 3.2 by the release of lactic acid by vaginal beneficial microorganisms, and at this low acidity, most harmful bacteria On the basis of inhibiting or killing growth, a buffer solution of pH 3.5 is proposed, which contains lactose as a main ingredient and lactoserum extracted from milk, but this is to maintain normal pH in the vagina rather than feminine cleaner. Intravaginal titration acidity maintainer.

Therefore, the first object of the present invention is to solve the conventional problems as described above, and an object of the present invention is to provide a cleaning composition for women and a method for producing the same without side effects or irritation caused by disinfectants.

A second object of the present invention is to provide a cleansing composition for women and a method for producing the same having excellent usability and cleaning power in addition to the first object described above.

The first and second objects of the present invention as described above are known as natural antibiotics having specific selectivity for pathogenic harmful bacteria and fungi, and bioactive substances that activate immune function and are defined in Food Code 13-25. It can be achieved by providing a female cleansing composition having a main component and a method for producing the same.

Specifically, according to the first aspect of the present invention for achieving the first object of the present invention, to provide a liquid detergent composition for women composed of propolis and purified water.

According to a second aspect of the present invention for achieving the first object of the present invention, it is to provide a powder cleaning composition for women coated or encapsulated with a propolis tea extract.

According to a third aspect of the present invention for achieving the second object of the present invention described above, it is to provide a female detergent composition comprising a surfactant added to the composition according to the second aspect of the present invention.

Hereinafter, the present invention will be described in more detail.

The composition according to the present invention contains propolis and / or propolis and tea extract as a main ingredient, and may optionally contain a certain amount of the surfactants commonly used in cleaning agents, and optionally contains a fragrance or disinfectant. It may contain an amount.

Liquid detergent composition according to the first aspect of the present invention is composed of 0.1 to 25 weight of propolis and 75 to 99.9 weight of purified water.

The powder cleaner composition according to the second aspect of the present invention is composed of 0.4 to 96.9 weight of propolis and 0.4 to 96.9 weight of tea extract mainly composed of polyphenols as antioxidants.

The detergent composition according to the third aspect of the present invention comprises 0.1 to 25 weight of propolis, 0.1 to 25 weight of tea extract mainly containing polyphenols as antioxidant, 0.3 to 25 weight of surfactant, and the balance of purified water.

Propolis as a main component of the present invention will be described. Excess purified water or high-purity (99.8 or more) ethanol is added to the propolis ingot powder collected from the beehive, and then placed in a cool dark place under standing or intermittent stirring for 1 to 3 days. After standing still and extracting propolis, after filtration, the filtrate is evaporated to a dark brown powder.

The first detergent composition according to the present invention is prepared by dissolving 0.1-25 weight of the propolis in 75-99.9 weight of purified water at 60-80 ° C. and then gradually cooling it. In the cleaning composition according to the present invention, if the content of propolis is less than 0.1 weight, the addition effect may not meet expectations, and if it exceeds 25 weight, it is not preferable because there is a possibility of precipitation in the cleaning agent.

On the other hand, the second detergent composition according to the present invention, by pouring an excess of water of 70 to 100 ℃ in the bulk amount of at least any one of the green tea, oolong tea and black tea leaves and left to stand for 1 to 6 hours or under intermittent stirring After the tea extract was obtained, the filtrate was filtered and the filtrate was evaporated to obtain an extract including green or brown powdered polyphenols and amino acids. Then, the propolis powder and the tea extract powder were 250: 1 to 1 in weight ratio. A ratio of: 250, preferably 25: 1 to 1:25, more preferably 10: 1 to 1:10, and 1 to 3 times the amount of purified water is added to the total weight of the mixture. Thereafter, the mixture is sufficiently stirred at a temperature of 60 to 80 ° C, and purified water is evaporated to prepare and coat or encapsulate the propolis with tea extract.

The second powdery detergent composition according to the present invention can be granulated, if necessary, and dissolved in about 1 to 50% by weight, preferably 1 to 25% by weight in hot water, or used in liquid form, or known soap phase. It can be formulated into gels or oils.

In addition, the detergent composition according to the third aspect of the present invention is prepared using the above-described detergent composition according to the second aspect, and is based on the total weight of the composition, based on the total weight of propolis from 0.1 to 25 weight, and a tea based on polyphenols as antioxidants. 0.1-25 weight of an extract, 0.1-3 weight of surfactant, and remainder consist of purified water.

As the surfactant that can be used in the detergent composition according to the third aspect of the present invention, any kind known in the art may be used as long as it is hypoallergenic and has excellent cleaning power. For example, anionic surfactant may have 8 carbon atoms. Alkali metal salts of alkyl sulfates, alkyl succinates, alkyl sacosinates, alkyl sulfosuccinates, alkyl phosphates of from 16 to 16; Alkali rare earth metal salts; And di- or triethanolamine salts of ammonium. Examples of the amphoteric surfactant include alkyl betaines having 10 to 18 carbon atoms, alkyl amidopropyl betaines, alkyl sulfo betaines or amine oxides. Examples of the warm surfactant include alkyl polyglycosides having 8 to 16 carbon atoms, cocoyl diethanol amine, and the like, and the above surfactants may be used alone or in combination of two or more thereof.

In addition, it is a matter of course that a known conventional adjuvant, that is, a moisturizing agent, a conditioning agent, a thickener, a neutralizing agent, a coloring agent and a flavoring agent, etc. can be used in trace amounts under conditions that do not cause skin irritation in the ingredients and the amount added. Specific examples of the thickener include polyacrylic acid, cationic polymers, nonionic polymers, cellulose derivatives or natural gums; Glycerin, polyethylene glycol, propylene glycol, lactic acid, urea or collagen as humectants; Polysaccharides or cellulose resins as conditioning agents; As the neutralizing agent, sodium hydroxide, potassium hydroxide or mono-, di- and triethanolamine and the like can be used, but the present invention is not limited thereto. In addition, the cleaning composition of the present invention using a conventional acid or a pharmaceutically acceptable sodium salt thereof, or more preferably using a lactic acid buffer solution to adjust the pH to about 3.2 to 3.8, preferably 3.4 to 3.6 Of course, this may help maintain the normal state of vaginal acidity.

In addition, the cleaning composition of this invention can be used in a liquid form or a gel form, and a gel composition can also use a conventional tube or pump type container.

Hereinafter, the present invention will be described in more detail with reference to Examples.

(Example)

Example 1

A few weeks after the nylon mesh was placed on the side wall of the bee hives, a high purity of 0.3 liters was applied to 100 g of propolis ingot obtained by applying a propolis-containing solution to remove the hardened nylon mesh. Ethanol was added, and the propolis was extracted by standing in a dark at 5 ° C for 2 days.

Subsequently, 9.2 g of propolis as a blackish brown powder was obtained by filtration using Whatman paper, concentrating the filtrate using a rotary vacuum evaporator, and then evaporating the remaining moisture in a desiccator overnight.

Then, after dissolving with a trace amount of perfume in 90.8 weight of purified water at 70 ℃, was slowly cooled and adjusted to pH 3.5 using lactic acid to prepare a cleaning composition.

Example 2

250 g of finely sliced green tea leaves were poured with excess water at 90 ° C. and left to stand for 3 hours to obtain a tea extract. The supernatant was collected, and the filtrate was evaporated to extract green tea extract containing green polyphenols and amino acids. Got.

Subsequently, after mixing with 9.2 g of propolis powder obtained in Example 1, 20 g of purified water was added thereto, warmed to a temperature of 70 ° C., stirred for 30 minutes using a Teflon magnetic stirrer, and then the stirring was stopped. Evaporating purified water while stirring occasionally with a glass rod in a stationary state, left overnight in a desiccator, dried, and then adding a trace amount of powder fragrance and granulating to increase solubility, thereby preparing a powdery detergent composition according to the present invention. Got it.

Example 3

A granulated mixture of 15 g of propolis and 5 g of green tea extract was obtained by the same procedure as in Example 2, followed by 0.2 g of lauryl diethanol amine as a surfactant and granulated as described above in an appropriate amount of purified water warmed to 70 ° C. After the mixture was added with stirring and uniformly dispersed or dissolved, the mixture was cooled to room temperature, a trace amount of fragrance was added, the pH was adjusted to 3.5fh, and a small amount of purified water was added to make the whole amount to 100 g. According to the cleaning composition was obtained.

Example 4

A cleaner composition according to the present invention was obtained by the same procedure as in Example 3, except that 5 g of propolis and 15 g of black tea extract were granulated and 1.5 g of glycerin was used as a surfactant.

Example 5

A cleaning composition according to the present invention was obtained by the same procedure as in Example 3, except that 0.5 g of propolis and 10 g of oolong tea extract were granulated, and 0.3 g of monoalkylphosphate triethanol amine was used as a surfactant.

Example 6

A cleaning composition according to the present invention was obtained by the same procedure as in Example 3, except that 3 g of propolis and 5 g of green tea extract were granulated, and 0.3 g of cocamido propylbetaine was used as a surfactant.

Example 7

A cleaner composition according to the present invention was obtained by the same procedure as in Example 3, except that 15 g of propolis and 10 g of black tea extract were used, and a mixture of 0.3 g of sodium lauroyl sarcosinate was used as a surfactant.

Example 8

15 g of propolis and 10 g of black tea extract were used, except that 0.1 g of disodium laurethsulfosuccinate, 0.1 g of cocamidopropyl amine oxide and 0.1 g of alkyl polyglucoside were used as surfactant. The cleaning composition according to the present invention was obtained by the same procedure as in Example 3.

Irritation test example

In order to test whether the female detergent composition prepared in Examples 1 to 8 was irritated, 15 women aged 20 to 40 years were allowed to use the composition as cleansing water using a bidet-mounted toilet bowl for one month and pruritus at the site of application. The presence or absence of subjective symptoms for burning or burning or erythema production was surveyed, and the results are averaged and shown in Table 1 below.

On the other hand, in the case of Example 2, 3 g of the powdery detergent composition was dissolved in 97 g of washing water and used.

<evaluation>

++: Irritating to mucous membranes.

+: It is not good to use because of severe irritation.

0: It is preferable to not use for sensitive mucosa because of slight irritation.

-: Almost no irritation.

=: No irritation and can be used for sensitive mucous membranes.

Example One 2 3 4 5 6 7 8 Score = = = = = = = =

Cleaning power test example

Lipsticks were rubbed into the upper arm of the left arm of 15 female subjects between the ages of 21 and 40 years, with an X-shape of 2 cm in diameter, and after 1 hour, 5 ml of the detergent was rubbed with a finger for 15 seconds and washed with water. The cleaning power was subjectively evaluated according to the following criteria, and the results are shown in Table 2 below.

5: washing with use, no residue

4: Slowly washed when using, no residue

3: Slowly wash off during use, leaving traces of lipstick

2: Difficult to remove, lipstick trail remains

1: not removed

Example One 2 3 4 5 6 7 8 Score 3.2 3.4 4.1 3.6 4.0 3.9 3.8 4.3

Sensory test example

In order to test the cleanliness, smell and stickiness of the women's cleaning composition prepared in Examples 1 to 8, 15 women of 20 to 40 years old used the above-mentioned composition as the cleaning water using a bidet-mounted toilet for one month. It was evaluated by subjective average of the relative feeling of making a blank (blank) using only a simple washing water containing no propolis and 1, and the results are shown in Table 3 below.

<evaluation>

++: much better than blank.

+: Generally better than blank.

0: about the same as the blank.

-: Not better than blank.

Example One 2 3 4 5 6 7 8 Score + + ++ + ++ ++ ++ ++

From the results of the above Tables 1 to 3, it can be seen that the cleaning composition according to the present invention is not irritating at all, the washing power is relatively excellent and the functionality is also good.

As described above, the propolis contains polymers with high adsorption properties, which is expected to have good applicability to the mucosal surface and exhibit specific growth inhibition or killing ability against harmful bacteria and fungi in the vagina. The odor removal effect is also excellent, and the tea extract helps to break down fat on the mucosal surface, and is not irritating at all, and has a relatively good cleaning power and good sensory function.

Claims (11)

A female liquid detergent composition comprising 0.1 to 25 weight of propolis and 75 to 99.9 weight of purified water. The female liquid detergent composition according to claim 1, wherein the pH of the detergent composition is adjusted to 3.2 to 3.8. A powdered detergent composition for women comprising 0.4 to 96.9 weight of propolis and 0.4 to 99.6 weight of at least one tea extract selected from the group consisting of green tea, black tea and oolong tea. The female liquid detergent composition according to claim 3, wherein the composition is granulated. 0.1-25 weight of propolis, 0.1-25 weight of at least 1 tea extract chosen from the group which consists of green tea, black tea, and oolong tea, 0.3-25 weight of surfactant, and remainder consist of purified water. The female detergent composition according to claim 5, wherein the pH of the detergent composition is adjusted to 3.2 to 3.8. The method according to claim 5, wherein the surfactant is lauryl diethanol amine, glycerin, monoalkyl phosphate triethanol amine, cocamido propylbetaine, sodium lauroyl sarcosinate, disodium laureth sulfosuccinate, cocamido propyl At least one compound selected from the group consisting of amine oxides and alkyl polyglucosides. The composition of claim 5 wherein said composition comprises a moisturizing agent, conditioning agent, thickener, or flavoring agent in trace amounts. Method for producing a female powdery detergent composition consisting of the following steps: (A) a propolis extraction step of extracting propolis by adding ethanol or water to the propolis ingot, filtering and evaporating the filtrate to obtain a propolis powder, (B) Pour excess water at 70-100 ° C. to at least one tea leaf selected from the group consisting of finely sliced green tea leaves, black tea leaves and oolong tea leaves to obtain a tea extract, which is then filtered and the filtrate is evaporated to form a powder. Tea extract extraction step to obtain extract, (C) The above propolis powder and the above tea extract powder are mixed in a weight ratio of 250: 1 to 1: 250, and purified water is added thereto, followed by stirring sufficiently at a temperature of 60 to 80 ° C, and purified water is evaporated. Propolis coating step of coating or encapsulating propolis with tea extract, 10. The method of claim 9, further comprising the step (D) granulation of granulating the mixture after step (C). The method of claim 9, wherein the propolis powder and the tea extract powder are mixed in a ratio of 25: 1 to 1:25 by weight.