KR20010022026A - Hcv의 e2 당단백질 중 초가변영역 1의 미모토프 및이것의 용도 - Google Patents

Hcv의 e2 당단백질 중 초가변영역 1의 미모토프 및이것의 용도 Download PDF

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Publication number
KR20010022026A
KR20010022026A KR1020007000594A KR20007000594A KR20010022026A KR 20010022026 A KR20010022026 A KR 20010022026A KR 1020007000594 A KR1020007000594 A KR 1020007000594A KR 20007000594 A KR20007000594 A KR 20007000594A KR 20010022026 A KR20010022026 A KR 20010022026A
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peptide
peptides
hcv
composition
antibody
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Korean (ko)
Inventor
니코시아알프레도
람아르민
트라몬타노안나
코르테스리카르도
Original Assignee
리카르도 코르테스
이스티투토 디 리세르쉐 디 비올로지아 몰레콜라레 피. 안젤레티에스.피.에이.
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Publication of KR20010022026A publication Critical patent/KR20010022026A/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020007000594A 1998-05-19 1999-05-14 Hcv의 e2 당단백질 중 초가변영역 1의 미모토프 및이것의 용도 Withdrawn KR20010022026A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9810756.8A GB9810756D0 (en) 1998-05-19 1998-05-19 Mimotopes of hypervariable region 1 of the e2 glycoprotein of hcv and uses thereof
GB9810756.8 1998-05-19
PCT/EP1999/003344 WO1999060132A1 (en) 1998-05-19 1999-05-14 Mimotopes of hypervariable region 1 of the e2 glycoprotein of hcv and uses thereof

Publications (1)

Publication Number Publication Date
KR20010022026A true KR20010022026A (ko) 2001-03-15

Family

ID=10832337

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007000594A Withdrawn KR20010022026A (ko) 1998-05-19 1999-05-14 Hcv의 e2 당단백질 중 초가변영역 1의 미모토프 및이것의 용도

Country Status (13)

Country Link
US (1) US7034108B1 (enExample)
EP (1) EP1002092B1 (enExample)
JP (1) JP4593780B2 (enExample)
KR (1) KR20010022026A (enExample)
CN (1) CN1274387A (enExample)
AT (1) ATE308618T1 (enExample)
AU (1) AU766610B2 (enExample)
CA (1) CA2297408C (enExample)
DE (1) DE69928064T2 (enExample)
DK (1) DK1002092T3 (enExample)
ES (1) ES2251832T3 (enExample)
GB (1) GB9810756D0 (enExample)
WO (1) WO1999060132A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2809402A1 (fr) * 2000-05-26 2001-11-30 Dev Des Antigenes Combinatoire Bibliotheques peptidiques combinatoires convergentes et leur application a la vaccination contre le virus de l'hepatite c
EP1290230A4 (en) * 2000-06-02 2004-10-20 Merck & Co Inc HEPATITIS C VIRUS CONJUGATE
WO2002045743A2 (en) * 2000-12-09 2002-06-13 Cambridge University Technical Services Limited Hcv vaccines
JP4475561B2 (ja) 2001-10-11 2010-06-09 メルク・シャープ・エンド・ドーム・コーポレイション C型肝炎ウイルスワクチン
EP2172552A3 (en) 2001-10-11 2010-07-21 Merck Sharp & Dohme Corp. Recombinant nucleic acids comprising regions of AD6
CN1305898C (zh) * 2003-08-22 2007-03-21 中国科学院上海生命科学研究院 丙型肝炎病毒被膜蛋白hvr1模拟多肽、其编码基因及用途
EP1893636A2 (en) 2005-06-17 2008-03-05 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Hepatitis c virus nucleic acid vaccine
JP5031827B2 (ja) * 2006-06-01 2012-09-26 程云 予防或いは肝損傷を治療するペプチッド
WO2007146975A2 (en) * 2006-06-13 2007-12-21 Athenix Corporation Methods for generating genetic diversity by permutational mutagenesis
BRPI0719672A2 (pt) 2006-11-29 2013-12-24 Athenix Corp Molécula isolada de ácido nucleico, vetor, célula hospedeira, planta transgênica, semente transgênica, polipeptídeo isolado, método para produzir um polipeptídeo com atividade de resistência a herbicidas, método para conferir resistência a um herbicida em uma planta, planta, método para aumentar o vigor ou rendimento de uma planta, método para conferir resistência ao glifosato a uma planta
CN110078800B (zh) * 2019-04-24 2021-01-29 中国人民解放军第二军医大学 合成肽在制备防治肝炎病毒感染药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2067194C (en) 1989-10-05 2003-03-18 Glenn Kawasaki Cell-free synthesis and isolation of novel genes and polypeptides
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
IT1270939B (it) 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
ATE249838T1 (de) 1993-05-12 2003-10-15 Chiron Corp Konserviertes motiv der hepatitis c virus e2/ns1 region
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
US5492807A (en) 1993-11-19 1996-02-20 Santi; Daniel V. Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
US6110465A (en) * 1995-06-07 2000-08-29 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of hypervariable region 1 of the envelope 2 gene of isolates of hepatitis C virus and the use of reagents derived from these hypervariable sequences in diagnostic methods and vaccines
JPH11124398A (ja) * 1997-10-22 1999-05-11 Japan Energy Corp C型肝炎ウイルス由来の抗原ペプチドとそれを用いる抗体検査薬

Also Published As

Publication number Publication date
JP4593780B2 (ja) 2010-12-08
CA2297408A1 (en) 1999-11-25
CA2297408C (en) 2011-06-21
EP1002092B1 (en) 2005-11-02
ES2251832T3 (es) 2006-05-01
DE69928064T2 (de) 2006-07-20
DK1002092T3 (da) 2006-03-06
AU766610B2 (en) 2003-10-16
CN1274387A (zh) 2000-11-22
GB9810756D0 (en) 1998-07-15
WO1999060132A1 (en) 1999-11-25
DE69928064D1 (de) 2005-12-08
AU4143599A (en) 1999-12-06
ATE308618T1 (de) 2005-11-15
EP1002092A1 (en) 2000-05-24
JP2002515249A (ja) 2002-05-28
US7034108B1 (en) 2006-04-25

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Patent event date: 20000119

Patent event code: PA01051R01D

Comment text: International Patent Application

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PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid