DK1002092T3 - Mimotoper af hypervariabel region 1 af E2-glycoproteinet fra HCV og anvendelser deraf - Google Patents
Mimotoper af hypervariabel region 1 af E2-glycoproteinet fra HCV og anvendelser derafInfo
- Publication number
- DK1002092T3 DK1002092T3 DK99924978T DK99924978T DK1002092T3 DK 1002092 T3 DK1002092 T3 DK 1002092T3 DK 99924978 T DK99924978 T DK 99924978T DK 99924978 T DK99924978 T DK 99924978T DK 1002092 T3 DK1002092 T3 DK 1002092T3
- Authority
- DK
- Denmark
- Prior art keywords
- hcv
- mimotopes
- hypervariable region
- glycoprotein
- applications
- Prior art date
Links
- 108091007491 NSP3 Papain-like protease domains Proteins 0.000 title abstract 2
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 241000711549 Hepacivirus C Species 0.000 abstract 3
- 101710091045 Envelope protein Proteins 0.000 abstract 1
- 101710188315 Protein X Proteins 0.000 abstract 1
- 102100021696 Syncytin-1 Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810756.8A GB9810756D0 (en) | 1998-05-19 | 1998-05-19 | Mimotopes of hypervariable region 1 of the e2 glycoprotein of hcv and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1002092T3 true DK1002092T3 (da) | 2006-03-06 |
Family
ID=10832337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99924978T DK1002092T3 (da) | 1998-05-19 | 1999-05-14 | Mimotoper af hypervariabel region 1 af E2-glycoproteinet fra HCV og anvendelser deraf |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7034108B1 (enExample) |
| EP (1) | EP1002092B1 (enExample) |
| JP (1) | JP4593780B2 (enExample) |
| KR (1) | KR20010022026A (enExample) |
| CN (1) | CN1274387A (enExample) |
| AT (1) | ATE308618T1 (enExample) |
| AU (1) | AU766610B2 (enExample) |
| CA (1) | CA2297408C (enExample) |
| DE (1) | DE69928064T2 (enExample) |
| DK (1) | DK1002092T3 (enExample) |
| ES (1) | ES2251832T3 (enExample) |
| GB (1) | GB9810756D0 (enExample) |
| WO (1) | WO1999060132A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2809402A1 (fr) * | 2000-05-26 | 2001-11-30 | Dev Des Antigenes Combinatoire | Bibliotheques peptidiques combinatoires convergentes et leur application a la vaccination contre le virus de l'hepatite c |
| EP1290230A4 (en) * | 2000-06-02 | 2004-10-20 | Merck & Co Inc | HEPATITIS C VIRUS CONJUGATE |
| WO2002045743A2 (en) * | 2000-12-09 | 2002-06-13 | Cambridge University Technical Services Limited | Hcv vaccines |
| JP4475561B2 (ja) | 2001-10-11 | 2010-06-09 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｃ型肝炎ウイルスワクチン |
| EP2172552A3 (en) | 2001-10-11 | 2010-07-21 | Merck Sharp & Dohme Corp. | Recombinant nucleic acids comprising regions of AD6 |
| CN1305898C (zh) * | 2003-08-22 | 2007-03-21 | 中国科学院上海生命科学研究院 | 丙型肝炎病毒被膜蛋白hvr1模拟多肽、其编码基因及用途 |
| EP1893636A2 (en) | 2005-06-17 | 2008-03-05 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus nucleic acid vaccine |
| JP5031827B2 (ja) * | 2006-06-01 | 2012-09-26 | 程云 | 予防或いは肝損傷を治療するペプチッド |
| WO2007146975A2 (en) * | 2006-06-13 | 2007-12-21 | Athenix Corporation | Methods for generating genetic diversity by permutational mutagenesis |
| BRPI0719672A2 (pt) | 2006-11-29 | 2013-12-24 | Athenix Corp | Molécula isolada de ácido nucleico, vetor, célula hospedeira, planta transgênica, semente transgênica, polipeptídeo isolado, método para produzir um polipeptídeo com atividade de resistência a herbicidas, método para conferir resistência a um herbicida em uma planta, planta, método para aumentar o vigor ou rendimento de uma planta, método para conferir resistência ao glifosato a uma planta |
| CN110078800B (zh) * | 2019-04-24 | 2021-01-29 | 中国人民解放军第二军医大学 | 合成肽在制备防治肝炎病毒感染药物中的用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2067194C (en) | 1989-10-05 | 2003-03-18 | Glenn Kawasaki | Cell-free synthesis and isolation of novel genes and polypeptides |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| IT1270939B (it) | 1993-05-11 | 1997-05-26 | Angeletti P Ist Richerche Bio | Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili. |
| ATE249838T1 (de) | 1993-05-12 | 2003-10-15 | Chiron Corp | Konserviertes motiv der hepatitis c virus e2/ns1 region |
| AU8124694A (en) | 1993-10-29 | 1995-05-22 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| US5492807A (en) | 1993-11-19 | 1996-02-20 | Santi; Daniel V. | Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease |
| US6110465A (en) * | 1995-06-07 | 2000-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of hypervariable region 1 of the envelope 2 gene of isolates of hepatitis C virus and the use of reagents derived from these hypervariable sequences in diagnostic methods and vaccines |
| JPH11124398A (ja) * | 1997-10-22 | 1999-05-11 | Japan Energy Corp | Ｃ型肝炎ウイルス由来の抗原ペプチドとそれを用いる抗体検査薬 |
-
1998
- 1998-05-19 GB GBGB9810756.8A patent/GB9810756D0/en not_active Ceased
-
1999
- 1999-05-14 JP JP2000549738A patent/JP4593780B2/ja not_active Expired - Fee Related
- 1999-05-14 US US09/463,098 patent/US7034108B1/en not_active Expired - Fee Related
- 1999-05-14 WO PCT/EP1999/003344 patent/WO1999060132A1/en not_active Ceased
- 1999-05-14 CA CA2297408A patent/CA2297408C/en not_active Expired - Fee Related
- 1999-05-14 EP EP99924978A patent/EP1002092B1/en not_active Expired - Lifetime
- 1999-05-14 AT AT99924978T patent/ATE308618T1/de active
- 1999-05-14 DE DE69928064T patent/DE69928064T2/de not_active Expired - Lifetime
- 1999-05-14 AU AU41435/99A patent/AU766610B2/en not_active Ceased
- 1999-05-14 CN CN99801173A patent/CN1274387A/zh active Pending
- 1999-05-14 DK DK99924978T patent/DK1002092T3/da active
- 1999-05-14 ES ES99924978T patent/ES2251832T3/es not_active Expired - Lifetime
- 1999-05-14 KR KR1020007000594A patent/KR20010022026A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP4593780B2 (ja) | 2010-12-08 |
| CA2297408A1 (en) | 1999-11-25 |
| CA2297408C (en) | 2011-06-21 |
| EP1002092B1 (en) | 2005-11-02 |
| KR20010022026A (ko) | 2001-03-15 |
| ES2251832T3 (es) | 2006-05-01 |
| DE69928064T2 (de) | 2006-07-20 |
| AU766610B2 (en) | 2003-10-16 |
| CN1274387A (zh) | 2000-11-22 |
| GB9810756D0 (en) | 1998-07-15 |
| WO1999060132A1 (en) | 1999-11-25 |
| DE69928064D1 (de) | 2005-12-08 |
| AU4143599A (en) | 1999-12-06 |
| ATE308618T1 (de) | 2005-11-15 |
| EP1002092A1 (en) | 2000-05-24 |
| JP2002515249A (ja) | 2002-05-28 |
| US7034108B1 (en) | 2006-04-25 |
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