KR20000070229A - 세포들과 생체분자들이 소수성 표면에 접착되는 것을 조정하기 - Google Patents

세포들과 생체분자들이 소수성 표면에 접착되는 것을 조정하기 Download PDF

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KR20000070229A
KR20000070229A KR1019997006456A KR19997006456A KR20000070229A KR 20000070229 A KR20000070229 A KR 20000070229A KR 1019997006456 A KR1019997006456 A KR 1019997006456A KR 19997006456 A KR19997006456 A KR 19997006456A KR 20000070229 A KR20000070229 A KR 20000070229A
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egap
biomolecule
molecules
organism
molecule
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Korean (ko)
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패트릭에이. 트레스코
카린디. 칼드웰
제니퍼 네프
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크리스티나 얀센
유타대학연구재단
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02—Compounds containing any of the groups, e.g. carbazates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1019997006456A 1997-01-15 1998-01-15 세포들과 생체분자들이 소수성 표면에 접착되는 것을 조정하기 Withdrawn KR20000070229A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8/784,203 1997-01-15
US08/784,203 US6284503B1 (en) 1993-08-20 1997-01-15 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces

Publications (1)

Publication Number Publication Date
KR20000070229A true KR20000070229A (ko) 2000-11-25

Family

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Application Number Title Priority Date Filing Date
KR1019997006456A Withdrawn KR20000070229A (ko) 1997-01-15 1998-01-15 세포들과 생체분자들이 소수성 표면에 접착되는 것을 조정하기

Country Status (10)

Country Link
US (3) US6284503B1 (enExample)
EP (1) EP1002066B1 (enExample)
JP (1) JP2001512565A (enExample)
KR (1) KR20000070229A (enExample)
AT (1) ATE501249T1 (enExample)
AU (1) AU740877B2 (enExample)
CA (1) CA2277995C (enExample)
DE (1) DE69842166D1 (enExample)
IL (2) IL130961A0 (enExample)
WO (1) WO1998031734A1 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284503B1 (en) 1993-08-20 2001-09-04 University Of Utah Research Foundation Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
ES2353840T3 (es) * 1997-04-21 2011-03-07 California Institute Of Technology Recubrimientos tisulares poliméricos multifuncionales.
DE19748489A1 (de) * 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
AR021240A1 (es) * 1998-11-13 2002-07-03 Commw Scient Ind Res Org Peptidos acoplados
WO2000065352A1 (en) * 1999-04-28 2000-11-02 Eidgenossisch Technische Hochschule Zurich Polyionic coatings in analytic and sensor devices
JP2001083162A (ja) * 1999-09-17 2001-03-30 Fuji Photo Film Co Ltd 膜状生体高分子吸着材及び吸着用キット
US7220276B1 (en) * 2000-03-06 2007-05-22 Surmodics, Inc. Endovascular graft coatings
US6706479B2 (en) * 2000-10-05 2004-03-16 Virginia Tech Intellectual Properties, Inc. Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips
WO2002030818A2 (en) * 2000-10-13 2002-04-18 University Of Cincinnati Methods for synthesizing precipitated silica and use thereof
DE10100961B4 (de) 2001-01-11 2005-08-04 Polyzenix Gmbh Körperverträglicher Werkstoff und mit diesem Werkstoff beschichtetes Substrat für die Züchtung von Zellen und künstlichen aus Zellen aufgebauten oder gewachsenen organischen Implantaten
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
CA2435894C (en) * 2001-02-02 2014-05-13 Allvivo, Inc. End group activated polymers with oligonucleotide ligands
US20050244843A1 (en) * 2001-11-16 2005-11-03 Wen-Tien Chen Blood test prototypes and methods for the detection of circulating tumor and endothelial cells
US20030148017A1 (en) * 2001-12-07 2003-08-07 Olli Tuominen Copolymer coating for a hydrophobic membrane
JP2005531616A (ja) * 2002-06-29 2005-10-20 アクヴァノヴァ・ジャーマン・ソリュービリセイト・テクノロジーズ・（アーゲーテー）・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング イソフラボン濃縮物およびその製造法
US8227411B2 (en) * 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
US7166574B2 (en) * 2002-08-20 2007-01-23 Biosurface Engineering Technologies, Inc. Synthetic heparin-binding growth factor analogs
US7598224B2 (en) 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US20050059140A1 (en) * 2003-09-12 2005-03-17 Andrea Liebmann-Vinson Methods of surface modification to enhance cell adhesion
DE10358565B4 (de) * 2003-12-15 2007-06-28 P.A.L.M. Microlaser Technologies Ag Aufnahmeelement zum Aufnehmen eines aus einer biologischen Masse mittels Laserstrahlung herausgelösten Objekts und Verfahren zur Gewinnung und Verarbeitung eines biologischen Objekts
US7414028B1 (en) 2004-02-04 2008-08-19 Biosurface Engineering Technologies, Inc. Growth factor analogs
US7528105B1 (en) 2004-02-10 2009-05-05 Biosurface Engineering Technologies Heterodimeric chain synthetic heparin-binding growth factor analogs
US20060024347A1 (en) * 2004-02-10 2006-02-02 Biosurface Engineering Technologies, Inc. Bioactive peptide coatings
US7671012B2 (en) 2004-02-10 2010-03-02 Biosurface Engineering Technologies, Inc. Formulations and methods for delivery of growth factor analogs
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
DE602005023714D1 (de) 2004-02-20 2010-11-04 Biosurface Eng Tech Inc Positiver modulator des knochenmorphogenetisches protein-2 (bmp-2)
EP1850858A2 (en) * 2005-02-10 2007-11-07 Emory University Polyethylene oxide polymers including anti-inflammatory glycodendrons
EP1712284B1 (en) * 2005-04-15 2012-10-10 Samsung Electronics Co., Ltd. Cell separation method using hydrophobic solid supports
US7749701B2 (en) * 2005-08-11 2010-07-06 Agilent Technologies, Inc. Controlling use of oligonucleotide sequences released from arrays
DE102005040211B4 (de) * 2005-08-16 2010-02-11 Maquet Cardiopulmonary Ag Verwendung von nichtionischen Estern in einer Beschichtung für mit Blut in Kontakt kommende Oberflächen und medizinische Vorrichtung
US20070225795A1 (en) * 2006-03-24 2007-09-27 Juan Granada Composite vascular prosthesis
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
EP2046350A4 (en) 2006-06-22 2011-09-14 Biosurface Eng Tech Inc COMPOSITION AND METHOD FOR DELIVERING AMPLIFIER / CO-ACTIVATOR OF BMP-2 TO ENHANCE OSTEOGENESIS
EP2069790B1 (en) * 2006-11-01 2015-04-29 Beckman Coulter, Inc. Binding surfaces for affinity assays
US20080187188A1 (en) * 2007-02-07 2008-08-07 Oleg Beletski Systems, apparatuses and methods for facilitating efficient recognition of delivered content
DK2150282T3 (en) * 2007-04-16 2018-07-23 Regentis Biomaterials Ltd COMPOSITIONS AND PROCEDURES FOR THE formation of a skeleton
US8529897B2 (en) * 2007-08-16 2013-09-10 Carnegie Mellon University Inflammation-regulating compositions and methods
KR101809863B1 (ko) 2008-01-30 2017-12-15 아스테리아스 바이오세라퓨틱스, 인크. 줄기 세포 유래 심근세포 배양용 합성 표면
CN105331577A (zh) 2008-01-30 2016-02-17 阿斯特利亚斯生物治疗股份公司 用于培养干细胞衍生的少突胶质细胞前体细胞的合成表面
DK2247716T3 (da) 2008-01-30 2012-05-29 Geron Corp Syntetiske overflader til dyrkning af celler i kemisk defineret medie
US8329469B2 (en) 2008-01-30 2012-12-11 Geron Corporation Swellable (meth)acrylate surfaces for culturing cells in chemically defined media
DE102008027133A1 (de) 2008-05-30 2009-12-03 Ls Medcap Gmbh Vollsynthetisches Albumin-Analogon
WO2010036257A1 (en) * 2008-09-25 2010-04-01 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
WO2010115243A1 (en) * 2009-04-09 2010-10-14 The University Of Queensland Block copolymer blends
DE102009040880B4 (de) * 2009-09-09 2012-10-18 Andreas Hettich Gmbh & Co. Kg Vorrichtung zur Durchführung von Tests zur Hämostase
US20110117166A1 (en) * 2009-11-18 2011-05-19 Affinergy, Inc. Implantable bone graft materials
KR20140147803A (ko) * 2011-09-30 2014-12-30 웨이크 포리스트 유니버시티 헬스 사이언시즈 운동 종말판 및 기타 특화 조직 구조의 형성을 위한 바이오스캐폴드
US11419962B2 (en) * 2016-06-27 2022-08-23 University Of Louisville Research Foundation, Inc. Spheroids including biologically-relevant materials and related methods
US10269569B2 (en) * 2016-11-29 2019-04-23 Taiwan Semiconductor Manufacturing Company, Ltd. Semiconductor device and methods of manufacture
JP7192314B2 (ja) * 2017-08-31 2022-12-20 東洋インキＳｃホールディングス株式会社 蛋白質、細胞又は微生物の接着抑制剤、並びにその用途
US10941274B1 (en) 2020-09-01 2021-03-09 King Abdulaziz University Nanoparticle-infused ABS filament for 3D-printed materials and uses for neutron detection and discrimination

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264766A (en) 1877-09-19 1981-04-28 Hoffmann-La Roche Inc. Immunological diagnostic reagents
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
SE420733B (sv) 1974-05-30 1981-10-26 Exploaterings Ab Tbf Gelprodukt, innehallande tiosulfatgrupper samt sett for framstellning derav
US3966580A (en) 1974-09-16 1976-06-29 The University Of Utah Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same
SE430062B (sv) 1977-03-04 1983-10-17 Pharmacia Fine Chemicals Ab Kopplings- eller tioleringsreagens
DE2850058A1 (de) 1978-11-18 1980-05-29 Bayer Ag Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4259474A (en) 1979-09-25 1981-03-31 Gaf Corporation Sulfur-containing polyoxyalkylenes
SE8102194L (sv) 1981-04-06 1982-10-07 Pharmacia Ab Terapeutiskt aktiv organisk forening och farmaceutisk beredning innehallande denna
US4609546A (en) 1982-06-24 1986-09-02 Japan Chemical Research Co., Ltd. Long-acting composition
DE3532593A1 (de) 1985-09-12 1987-03-12 Koemmerling Kunststoff Extrudierter kunststoffhohlprofilstab fuer rahmen von fenstern und tueren
DE3532626A1 (de) 1985-09-12 1987-03-19 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines partners einer immunreaktion
EP0263184B1 (en) 1986-03-28 1992-10-28 Toray Industries, Inc. Immobilized physiologically active material
US5567859A (en) 1991-03-19 1996-10-22 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US5674911A (en) 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
IE64284B1 (en) 1987-08-03 1995-07-26 Ddi Pharmaceuticals Conjugates of superoxide dismutase
US5006333A (en) 1987-08-03 1991-04-09 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US4929510A (en) 1988-04-29 1990-05-29 State University Of New York Biocompatible polymer articles
US5248820A (en) 1989-02-21 1993-09-28 Pfizer Inc. Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
CA2028804C (en) 1989-11-21 2000-06-20 Howard J. Buttery Biomosaic polymers and method for preparing same
US5219926A (en) 1989-12-29 1993-06-15 Berol Nobel Ab Method of covalently bonding biopolymer to a solid hydrophilic organic polymer
CA2101918A1 (en) 1991-03-18 1992-09-19 Samuel Zalipsky Hydrazine containing conjugates of polypeptides and glycopolypeptides with polymers
US5516703A (en) * 1993-08-20 1996-05-14 The University Of Utah Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
US6284503B1 (en) * 1993-08-20 2001-09-04 University Of Utah Research Foundation Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
BE1008955A3 (fr) 1994-11-14 1996-10-01 Univ Catholique Louvain Procede d'obtention de biomateriaux et produits obtenus.
US5783178A (en) 1994-11-18 1998-07-21 Supratek Pharma. Inc. Polymer linked biological agents
US5565188A (en) 1995-02-24 1996-10-15 Nanosystems L.L.C. Polyalkylene block copolymers as surface modifiers for nanoparticles

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JP2001512565A (ja) 2001-08-21
IL130961A (en) 2009-02-11
EP1002066B1 (en) 2011-03-09
DE69842166D1 (de) 2011-04-21
US6284503B1 (en) 2001-09-04
EP1002066A1 (en) 2000-05-24
CA2277995A1 (en) 1998-07-23
IL130961A0 (en) 2001-01-28
US20020019037A1 (en) 2002-02-14
AU6018298A (en) 1998-08-07
EP1002066A4 (en) 2004-12-01
WO1998031734A1 (en) 1998-07-23
US20040170964A1 (en) 2004-09-02
AU740877B2 (en) 2001-11-15
ATE501249T1 (de) 2011-03-15
US7208299B2 (en) 2007-04-24
US6670199B2 (en) 2003-12-30
CA2277995C (en) 2003-03-18

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