KR20000057506A - 1,5-benzodiazepine derivatives - Google Patents
1,5-benzodiazepine derivativesInfo
- Publication number
- KR20000057506A KR20000057506A KR1019990705193A KR19997005193A KR20000057506A KR 20000057506 A KR20000057506 A KR 20000057506A KR 1019990705193 A KR1019990705193 A KR 1019990705193A KR 19997005193 A KR19997005193 A KR 19997005193A KR 20000057506 A KR20000057506 A KR 20000057506A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- hydrogen atom
- same
- benzodiazepine derivatives
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8-344498 | 1996-12-10 | ||
JP34449896 | 1996-12-10 | ||
JP9-156132 | 1997-05-30 | ||
JP15613297 | 1997-05-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20000057506A true KR20000057506A (en) | 2000-09-15 |
KR100531235B1 KR100531235B1 (ko) | 2006-01-12 |
Family
ID=26483957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019997005193A KR100531235B1 (ko) | 1996-12-10 | 1997-12-10 | 1,5-벤조디아제핀 유도체 |
Country Status (12)
Country | Link |
---|---|
US (1) | US6239131B1 (ko) |
EP (1) | EP0945445B9 (ko) |
JP (1) | JP3999819B2 (ko) |
KR (1) | KR100531235B1 (ko) |
CN (1) | CN1130351C (ko) |
AT (1) | ATE248823T1 (ko) |
AU (1) | AU721081B2 (ko) |
CA (1) | CA2274669C (ko) |
DE (2) | DE69724644D1 (ko) |
ES (1) | ES2206754T3 (ko) |
PT (1) | PT945445E (ko) |
WO (1) | WO1998025911A1 (ko) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6683075B1 (en) | 1996-12-23 | 2004-01-27 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use |
JP2000026434A (ja) * | 1998-06-05 | 2000-01-25 | Zeria Pharmaceut Co Ltd | 新規1,5−ベンゾジアゼピン誘導体 |
US6569851B1 (en) | 1998-06-22 | 2003-05-27 | Elan Pharmaceutials, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6958330B1 (en) | 1998-06-22 | 2005-10-25 | Elan Pharmaceuticals, Inc. | Polycyclic α-amino-ε-caprolactams and related compounds |
US20030119029A1 (en) * | 1999-04-30 | 2003-06-26 | Regents Of The University Of Michigan | Compositions and methods relating to novel benzodiazepine compounds and targets thereof |
US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20060025388A1 (en) * | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
US7144880B2 (en) * | 1999-04-30 | 2006-12-05 | Regents Of The University Of Michigan | Compositions relating to novel compounds and targets thereof |
ATE258439T1 (de) | 1999-04-30 | 2004-02-15 | Univ Michigan | Verwendung von benzodiazepinen zur behandlung von apoptose-induzierten autoimmunerkrankungen |
US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
PT1234818E (pt) | 1999-12-02 | 2005-01-31 | Zeria Pharm Co Ltd | Sais de calcio de derivados de 1,5-benzodiazepina, processo para producao dos sais e drogas que os contem |
US20050192265A1 (en) * | 2003-03-20 | 2005-09-01 | Thompson Richard C. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds |
KR20050119666A (ko) | 2003-03-28 | 2005-12-21 | 얀센 파마슈티카 엔.브이. | 벤조[1,2,5]티아디아졸 화합물 |
PT1651621E (pt) | 2003-08-08 | 2008-09-30 | Janssen Pharmaceutica Nv | Compostos de 2-(quinoxalin-5-ilsulfonilamino)-benzamida como moduladores de cck2 |
US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
US7947833B2 (en) * | 2004-08-04 | 2011-05-24 | Janssen Pharmaceutica Nv | Preparation of quinoxaline compounds |
US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
CN101061116A (zh) * | 2004-09-24 | 2007-10-24 | 詹森药业有限公司 | 磺酰胺化合物 |
CA2593019A1 (en) * | 2005-01-03 | 2006-07-13 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
DE602006013094D1 (de) * | 2005-01-19 | 2010-05-06 | Zeria Pharm Co Ltd | Krebsmittel |
JP2008545757A (ja) | 2005-06-01 | 2008-12-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 溶媒和されていないベンゾジアゼピン組成物および方法 |
US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
WO2007053725A2 (en) | 2005-11-01 | 2007-05-10 | The Regents Of The University Of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
AU2007258468B2 (en) | 2006-06-09 | 2011-09-22 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
MX2009002538A (es) * | 2006-09-20 | 2009-03-20 | Hoffmann La Roche | Derivados de 4-oxo-2,3,4,5-tetrahidro-benzo[b][1,4]diazepina. |
CA2783589A1 (en) | 2007-03-09 | 2008-09-18 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
ES2614498T3 (es) | 2007-09-14 | 2017-05-31 | The Regents Of The University Of Michigan | Inhibidores de ATPasa F1F0 y métodos relacionados |
BRPI0820477A2 (pt) | 2007-11-06 | 2015-06-16 | Univ Michigan | Compostos de benzodiazepinona úteis no tratamento de afecções da pele |
TWI459948B (zh) * | 2008-05-15 | 2014-11-11 | Zeria Pharm Co Ltd | The use of a 1,5-benzodiazepine derivative or a pharmaceutically acceptable salt thereof for the manufacture of a pain therapeutic agent composition |
AU2009291632B2 (en) | 2008-09-11 | 2013-04-04 | The Regents Of The University Of Michigan | Aryl guanidine F1F0-ATPase inhibitors and related methods |
US20110319396A1 (en) * | 2009-01-23 | 2011-12-29 | Msd K.K. | Benzodiazepin-2-on derivatives |
RU2011143755A (ru) * | 2009-03-31 | 2013-05-10 | Зериа Фармасьютикал Ко., Лтд. | Способ получения производного 1,5-бензодиазепина |
WO2010121164A2 (en) | 2009-04-17 | 2010-10-21 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
US8673897B2 (en) | 2009-09-18 | 2014-03-18 | The Regents Of The University Of Michigan | Benzodiazepinone compounds and methods of treatment using same |
JP5856064B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する1,4−ベンゾジアゼピン−2,5−ジオンおよび関連化合物 |
EP2501387B1 (en) | 2009-11-17 | 2016-07-27 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
KR20120052884A (ko) | 2010-11-15 | 2012-05-24 | 롬 앤드 하스 일렉트로닉 머트어리얼즈, 엘.엘.씨. | 염기 반응성 포토애시드 발생제 및 이를 포함하는 포토레지스트 |
JP2019131467A (ja) * | 2016-04-08 | 2019-08-08 | ゼリア新薬工業株式会社 | 1,5−ベンゾジアゼピン化合物の結晶 |
JP2019167295A (ja) * | 2016-07-04 | 2019-10-03 | ゼリア新薬工業株式会社 | 1,5−ベンゾジアゼピン化合物カルシウム塩の製造法 |
CN106243050B (zh) * | 2016-08-10 | 2019-09-06 | 安徽恒星制药有限公司 | 一种适合工业化生产氯巴占的方法 |
WO2019034532A1 (en) * | 2017-08-15 | 2019-02-21 | Bayer Aktiengesellschaft | 4-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-7-carboxamides |
WO2019246541A1 (en) * | 2018-06-21 | 2019-12-26 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GEP20001968B (en) * | 1992-01-21 | 2000-03-05 | Glaxo Spa | Arilthio Compounds as Antibacterial and Antiviral Agents |
GB2272439A (en) * | 1992-11-13 | 1994-05-18 | Merck & Co Inc | Benzo-fused lactams that inhibit the release of growth hormone |
SK125495A3 (en) * | 1993-04-15 | 1996-06-05 | Glaxo Wellcome Inc | 1,5-benzodiazepine derivatives, manufacturing process, their use and pharmaceutical compositions containing them |
GB9307833D0 (en) * | 1993-04-15 | 1993-06-02 | Glaxo Inc | Modulators of cholecystokinin and gastrin |
GB9308431D0 (en) * | 1993-04-23 | 1993-06-09 | Glaxo Spa | Chemical compounds |
GB2282595A (en) * | 1993-08-25 | 1995-04-12 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives |
AU1371895A (en) * | 1993-12-13 | 1995-07-03 | Merck & Co., Inc. | Benzo-fused lactams promote release of growth hormone |
PT728748E (pt) * | 1993-12-28 | 2002-06-28 | Shionogi & Co | Novos derivados da benzodiazepina |
US5739129A (en) * | 1994-04-14 | 1998-04-14 | Glaxo Wellcome Inc. | CCK or gastrin modulating 5-heterocyclic-1, 5 benzodiazepines |
KR970702274A (ko) * | 1994-04-14 | 1997-05-13 | 앨런 헤스케쓰 | 콜레시스토키닌 또는 가스트린을 조절하는 5-헤테로시클릭-1, 5-벤조디아제핀(CCK or Gastrin Modulating 5-Heterocyclic-1,5-Benzodiazepines) |
US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
JPH11506760A (ja) * | 1995-06-07 | 1999-06-15 | メルク エンド カンパニー インコーポレーテッド | 新規なn−(2,4−ジオキソ−2,3,4,5−テトラヒドロ−1h−1,5−ベンゾジアゼピン−3イル)−3−アミド |
-
1997
- 1997-12-10 DE DE69724644A patent/DE69724644D1/de not_active Expired - Lifetime
- 1997-12-10 KR KR1019997005193A patent/KR100531235B1/ko not_active IP Right Cessation
- 1997-12-10 PT PT97947872T patent/PT945445E/pt unknown
- 1997-12-10 EP EP97947872A patent/EP0945445B9/en not_active Expired - Lifetime
- 1997-12-10 JP JP52649598A patent/JP3999819B2/ja not_active Expired - Fee Related
- 1997-12-10 ES ES97947872T patent/ES2206754T3/es not_active Expired - Lifetime
- 1997-12-10 AT AT97947872T patent/ATE248823T1/de active
- 1997-12-10 DE DE69724644T patent/DE69724644T4/de not_active Expired - Lifetime
- 1997-12-10 US US09/319,249 patent/US6239131B1/en not_active Expired - Lifetime
- 1997-12-10 CN CN97181599A patent/CN1130351C/zh not_active Expired - Lifetime
- 1997-12-10 CA CA002274669A patent/CA2274669C/en not_active Expired - Lifetime
- 1997-12-10 WO PCT/JP1997/004534 patent/WO1998025911A1/ja active IP Right Grant
- 1997-12-10 AU AU54100/98A patent/AU721081B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CN1130351C (zh) | 2003-12-10 |
DE69724644D1 (de) | 2003-10-09 |
AU5410098A (en) | 1998-07-03 |
US6239131B1 (en) | 2001-05-29 |
CN1246850A (zh) | 2000-03-08 |
ATE248823T1 (de) | 2003-09-15 |
AU721081B2 (en) | 2000-06-22 |
PT945445E (pt) | 2004-01-30 |
EP0945445B9 (en) | 2005-12-28 |
EP0945445B1 (en) | 2003-09-03 |
WO1998025911A1 (fr) | 1998-06-18 |
KR100531235B1 (ko) | 2006-01-12 |
DE69724644T4 (de) | 2006-08-10 |
CA2274669C (en) | 2006-11-14 |
EP0945445A1 (en) | 1999-09-29 |
EP0945445A4 (en) | 2002-05-08 |
JP3999819B2 (ja) | 2007-10-31 |
DE69724644T2 (de) | 2004-06-17 |
ES2206754T3 (es) | 2004-05-16 |
CA2274669A1 (en) | 1998-06-18 |
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