KR102889007B1 - T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 - Google Patents
T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단Info
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- KR102889007B1 KR102889007B1 KR1020247020607A KR20247020607A KR102889007B1 KR 102889007 B1 KR102889007 B1 KR 102889007B1 KR 1020247020607 A KR1020247020607 A KR 1020247020607A KR 20247020607 A KR20247020607 A KR 20247020607A KR 102889007 B1 KR102889007 B1 KR 102889007B1
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662425398P | 2016-11-22 | 2016-11-22 | |
| US62/425,398 | 2016-11-22 | ||
| US201762543696P | 2017-08-10 | 2017-08-10 | |
| US62/543,696 | 2017-08-10 | ||
| KR1020197016703A KR20190085528A (ko) | 2016-11-22 | 2017-11-22 | T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 |
| PCT/US2017/063048 WO2018098306A1 (en) | 2016-11-22 | 2017-11-22 | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197016703A Division KR20190085528A (ko) | 2016-11-22 | 2017-11-22 | T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20240099512A KR20240099512A (ko) | 2024-06-28 |
| KR102889007B1 true KR102889007B1 (ko) | 2025-11-21 |
Family
ID=62193475
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247020607A Active KR102889007B1 (ko) | 2016-11-22 | 2017-11-22 | T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 |
| KR1020197016703A Ceased KR20190085528A (ko) | 2016-11-22 | 2017-11-22 | T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197016703A Ceased KR20190085528A (ko) | 2016-11-22 | 2017-11-22 | T 세포 악성종양의 면역요법을 위한 키메라 항원 수용체 및 cd7 발현의 차단 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10550183B2 (https=) |
| EP (1) | EP3545082A4 (https=) |
| JP (3) | JP7778468B2 (https=) |
| KR (2) | KR102889007B1 (https=) |
| CN (3) | CN110268049B (https=) |
| AU (3) | AU2017363278B2 (https=) |
| CA (1) | CA3043752A1 (https=) |
| NZ (1) | NZ752984A (https=) |
| SG (2) | SG10201912387PA (https=) |
| WO (1) | WO2018098306A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015116943A2 (en) | 2014-01-31 | 2015-08-06 | Monolith Materials, Inc. | Plasma torch design |
| KR102705340B1 (ko) | 2015-02-03 | 2024-09-09 | 모놀리스 머티어리얼스 인코포레이티드 | 카본 블랙 생성 시스템 |
| KR102763121B1 (ko) | 2015-02-06 | 2025-02-04 | 내셔널 유니버시티 오브 싱가포르 | 치료적 면역 세포의 효능의 향상 방법 |
| CA3032246C (en) | 2015-07-29 | 2023-12-12 | Monolith Materials, Inc. | Dc plasma torch electrical power design method and apparatus |
| CA2995081C (en) | 2015-08-07 | 2023-10-03 | Monolith Materials, Inc. | Method of making carbon black |
| EP3347306A4 (en) | 2015-09-09 | 2019-04-17 | Monolith Materials, Inc. | CIRCULAR SINGLE-LAYER GRAPH |
| KR102546839B1 (ko) | 2016-08-03 | 2023-06-23 | 워싱턴 유니버시티 | 키메라 항원 수용체를 이용한 t 세포 악성종양의 치료를 위한 car-t 세포의 유전자 편집 |
| NZ752984A (en) | 2016-11-22 | 2026-03-27 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| CA3287539A1 (en) | 2017-06-21 | 2026-03-02 | Icell Gene Therapeutics Llc | CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF |
| US20190038733A1 (en) | 2017-08-10 | 2019-02-07 | National University Of Singapore | T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof |
| EP3784776A4 (en) | 2018-05-23 | 2022-01-26 | National University of Singapore | Blockade of cd2 surface expression and expression of chimeric antigen receptors for immunotherapy of t-cell malignancies |
| US10227576B1 (en) | 2018-06-13 | 2019-03-12 | Caribou Biosciences, Inc. | Engineered cascade components and cascade complexes |
| US12227776B2 (en) | 2018-06-13 | 2025-02-18 | Caribou Biosciences, Inc. | Engineered cascade components and cascade complexes |
| EP3743512A4 (en) | 2018-10-31 | 2021-12-01 | Nantkwest, Inc. | ELIMINATION OF CD19 POSITIVE LYMPHOID MALIGNITIES BY CD19 CAR EXPRESSING NK CELLS |
| AU2019372673A1 (en) | 2018-11-01 | 2021-05-27 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for T cell engineering |
| MA53877A (fr) | 2018-11-14 | 2022-01-19 | MediSix Therapeutics Pte Ltd | Vecteurs à deux gènes pour la génération de cellules car-t et utilisations associées |
| CN109652379B (zh) * | 2018-12-29 | 2022-08-16 | 博生吉医药科技(苏州)有限公司 | Cd7嵌合抗原受体修饰的nk-92mi细胞及其应用 |
| US11840575B2 (en) | 2019-05-07 | 2023-12-12 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Engineered immune cells targeting BCMA and their uses thereof |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| CA3154218A1 (en) * | 2019-10-11 | 2021-04-15 | Crystal Mackall | Recombinant polypeptides for regulatable cellular localization |
| AU2020388690A1 (en) * | 2019-11-20 | 2022-06-09 | Cartherics Pty. Ltd. | Method for providing immune cells with enhanced function |
| JP2023504884A (ja) * | 2019-12-05 | 2023-02-07 | ヴィセリックス・インコーポレーティッド | ユニバーサル細胞療法のための免疫逃避機構のモジュレーター |
| US20230019849A1 (en) * | 2019-12-09 | 2023-01-19 | St. Jude Children's Research Hospital, Inc. | Method for Preparing CD7-Negative, CD3-Positive T Cells |
| US12312407B2 (en) * | 2020-01-30 | 2025-05-27 | St Phi Therapeutics Co., Ltd. | Universal T cells and the method of use thereof |
| CN112300282A (zh) * | 2020-11-03 | 2021-02-02 | 南京北恒生物科技有限公司 | 靶向cd7的人源化抗体及其用途 |
| CN114525259B (zh) * | 2020-11-03 | 2025-02-14 | 南京北恒生物科技有限公司 | 靶向cd7的嵌合抗原受体及其用途 |
| EP4243839A1 (en) | 2020-11-13 | 2023-09-20 | Catamaran Bio, Inc. | Genetically modified natural killer cells and methods of use thereof |
| CN114525306B (zh) * | 2020-11-23 | 2025-01-28 | 博生吉医药科技(苏州)有限公司 | 一种cd7-car-t细胞的制备方法及应用 |
| AU2021386367A1 (en) | 2020-11-24 | 2023-06-22 | Les Laboratoires Servier | Bcl-xl inhibitor antibody-drug conjugates and methods of use thereof |
| CN113234682B (zh) * | 2021-01-12 | 2023-02-21 | 上海雅科生物科技有限公司 | 靶向cd7的工程化免疫细胞、嵌合抗原受体、cd7阻断分子及应用 |
| WO2022161502A1 (zh) * | 2021-02-01 | 2022-08-04 | 羿尊生物医药(浙江)有限公司 | 一种靶向蛋白降解系统及其应用 |
| CN114853900A (zh) * | 2021-02-03 | 2022-08-05 | 南京北恒生物科技有限公司 | 新型嵌合抗原受体及其用途 |
| CN115044617B (zh) * | 2021-03-08 | 2024-08-13 | 河北森朗生物科技有限公司 | Car t细胞的制备方法、car t细胞及其应用 |
| CN112980800A (zh) * | 2021-03-08 | 2021-06-18 | 河北森朗生物科技有限公司 | Car-t细胞、其构建方法及其应用 |
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| US20250222026A1 (en) * | 2021-06-08 | 2025-07-10 | Beijing Meikang Geno-Immune Biotechnology Co., Ltd. | Cd7-based humanized chimeric antigen receptor and use thereof |
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