KR102876612B1 - 하나 이상의 비-고유 꼬리 섬유를 가지는 비-복제성 형질도입 입자 및 형질도입 입자-기반 리포터 시스템 - Google Patents
하나 이상의 비-고유 꼬리 섬유를 가지는 비-복제성 형질도입 입자 및 형질도입 입자-기반 리포터 시스템Info
- Publication number
- KR102876612B1 KR102876612B1 KR1020217021360A KR20217021360A KR102876612B1 KR 102876612 B1 KR102876612 B1 KR 102876612B1 KR 1020217021360 A KR1020217021360 A KR 1020217021360A KR 20217021360 A KR20217021360 A KR 20217021360A KR 102876612 B1 KR102876612 B1 KR 102876612B1
- Authority
- KR
- South Korea
- Prior art keywords
- tail fiber
- bacteriophage
- myoviridae
- tail
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/14—Streptococcus; Staphylococcus
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10041—Use of virus, viral particle or viral elements as a vector
- C12N2795/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10123—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10151—Methods of production or purification of viral material
- C12N2795/10152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10341—Use of virus, viral particle or viral elements as a vector
- C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10351—Methods of production or purification of viral material
- C12N2795/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
- C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
- G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862787151P | 2018-12-31 | 2018-12-31 | |
| US62/787,151 | 2018-12-31 | ||
| US201962926989P | 2019-10-28 | 2019-10-28 | |
| US62/926,989 | 2019-10-28 | ||
| PCT/EP2019/086888 WO2020141124A2 (en) | 2018-12-31 | 2019-12-22 | Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20210110826A KR20210110826A (ko) | 2021-09-09 |
| KR102876612B1 true KR102876612B1 (ko) | 2025-10-24 |
Family
ID=69105862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217021360A Active KR102876612B1 (ko) | 2018-12-31 | 2019-12-22 | 하나 이상의 비-고유 꼬리 섬유를 가지는 비-복제성 형질도입 입자 및 형질도입 입자-기반 리포터 시스템 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11572595B2 (https=) |
| EP (1) | EP3906304A2 (https=) |
| JP (1) | JP7636328B2 (https=) |
| KR (1) | KR102876612B1 (https=) |
| CN (1) | CN113272424A (https=) |
| AU (1) | AU2019419691B2 (https=) |
| CA (1) | CA3124760A1 (https=) |
| SG (1) | SG11202107109SA (https=) |
| WO (1) | WO2020141124A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108410825B (zh) * | 2018-04-20 | 2022-09-20 | 南京农业大学 | 一种噬菌体鸡尾酒及其应用 |
| KR20220066303A (ko) | 2019-09-11 | 2022-05-24 | 더 스크립스 리서치 인스티튜트 | 항바이러스 전구약물 및 이의 약제학적 조성물 |
| WO2021188959A1 (en) * | 2020-03-20 | 2021-09-23 | Gilead Sciences, Inc. | Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same |
| WO2023187041A1 (en) * | 2022-03-30 | 2023-10-05 | Biological Research Centre | Metagenomic libraries |
| CN115927214B (zh) * | 2022-12-21 | 2024-03-22 | 暨南大学 | 基于双元系统高效改变噬菌体制剂宿主范围的方法及其应用 |
| EP4621049A1 (en) * | 2024-03-19 | 2025-09-24 | Invitris GmbH | Multispecific particles |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017114979A1 (en) | 2016-01-03 | 2017-07-06 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| IL79289A (en) | 1985-07-05 | 1992-01-15 | Whitehead Biomedical Inst | Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| ATE117375T1 (de) | 1987-09-11 | 1995-02-15 | Whitehead Biomedical Inst | Transduktionsveränderte fibroblasten und ihre anwendung. |
| JP2914692B2 (ja) | 1987-12-11 | 1999-07-05 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 内皮細胞の遺伝子修飾 |
| WO1989007136A2 (en) | 1988-02-05 | 1989-08-10 | Whitehead Institute For Biomedical Research | Modified hepatocytes and uses therefor |
| ES2096750T3 (es) | 1990-10-31 | 1997-03-16 | Somatix Therapy Corp | Vectores retroviricos utiles para la terapia genica. |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| US5587308A (en) | 1992-06-02 | 1996-12-24 | The United States Of America As Represented By The Department Of Health & Human Services | Modified adeno-associated virus vector capable of expression from a novel promoter |
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| US6054299A (en) | 1994-04-29 | 2000-04-25 | Conrad; Charles A. | Stem-loop cloning vector and method |
| JP2002527061A (ja) | 1998-10-09 | 2002-08-27 | インジーン・インコーポレイテッド | ssDNAの酵素的合成 |
| MXPA01003643A (es) | 1998-10-09 | 2003-07-21 | Ingene Inc | Produccion de adnss in vivo. |
| AU2005324479A1 (en) | 2004-04-07 | 2006-07-20 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Reporter plasmid phage packaging system for detection of bacteria |
| BRPI0711969A2 (pt) | 2006-05-15 | 2012-01-24 | Avidbiotics Corp | bacteriocinas modificadas e métodos para seu uso |
| US7700729B2 (en) | 2006-05-15 | 2010-04-20 | Avidbiotics Corporation | Modified bacteriocins and methods for their use |
| US8445639B2 (en) | 2006-05-15 | 2013-05-21 | Avidbiotics Corporation | Recombinant bacteriophage and methods for their use |
| DK2968424T3 (da) * | 2013-03-13 | 2020-03-30 | Geneweave Biosciences Inc | Ikke-replikative transduktionspartikler og transduktionspartikelbaserede reportersystemer |
| WO2015035168A1 (en) | 2013-09-05 | 2015-03-12 | Massachusetts Institute Of Technolgy | Tuning bacteriophage host range |
| ES2778727T3 (es) | 2014-08-25 | 2020-08-11 | Geneweave Biosciences Inc | Partículas de transducción no replicativas y sistemas indicadores basados en partículas de transducción |
| GB201417805D0 (en) | 2014-10-08 | 2014-11-19 | Phico Therapeutics Ltd | Modifield bacteriophage |
| GB201417808D0 (en) | 2014-10-08 | 2014-11-19 | Phico Therapeutics Ltd | Modified bacteriophage |
| US9879328B2 (en) | 2014-11-21 | 2018-01-30 | GeneWeave Biosciences, Inc. | Mechanisms of antimicrobial susceptibility |
-
2019
- 2019-12-20 US US16/722,724 patent/US11572595B2/en active Active
- 2019-12-22 AU AU2019419691A patent/AU2019419691B2/en active Active
- 2019-12-22 SG SG11202107109SA patent/SG11202107109SA/en unknown
- 2019-12-22 WO PCT/EP2019/086888 patent/WO2020141124A2/en not_active Ceased
- 2019-12-22 EP EP19832138.2A patent/EP3906304A2/en active Pending
- 2019-12-22 CA CA3124760A patent/CA3124760A1/en active Pending
- 2019-12-22 CN CN201980087245.3A patent/CN113272424A/zh active Pending
- 2019-12-22 KR KR1020217021360A patent/KR102876612B1/ko active Active
- 2019-12-22 JP JP2021538003A patent/JP7636328B2/ja active Active
-
2023
- 2023-01-10 US US18/152,432 patent/US20230272491A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017114979A1 (en) | 2016-01-03 | 2017-07-06 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020141124A2 (en) | 2020-07-09 |
| JP7636328B2 (ja) | 2025-02-26 |
| KR20210110826A (ko) | 2021-09-09 |
| AU2019419691A1 (en) | 2021-07-08 |
| CN113272424A (zh) | 2021-08-17 |
| US20200208226A1 (en) | 2020-07-02 |
| JP2022515857A (ja) | 2022-02-22 |
| EP3906304A2 (en) | 2021-11-10 |
| WO2020141124A3 (en) | 2020-08-13 |
| US20230272491A1 (en) | 2023-08-31 |
| CA3124760A1 (en) | 2020-07-09 |
| US11572595B2 (en) | 2023-02-07 |
| SG11202107109SA (en) | 2021-07-29 |
| AU2019419691B2 (en) | 2025-09-11 |
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