CA3124760A1 - Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems - Google Patents

Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems Download PDF

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Publication number
CA3124760A1
CA3124760A1 CA3124760A CA3124760A CA3124760A1 CA 3124760 A1 CA3124760 A1 CA 3124760A1 CA 3124760 A CA3124760 A CA 3124760A CA 3124760 A CA3124760 A CA 3124760A CA 3124760 A1 CA3124760 A1 CA 3124760A1
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Prior art keywords
tail
myoviridae
genes
lysogen
bacteriophage
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Pending
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CA3124760A
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English (en)
French (fr)
Inventor
Kyle C. Cady
Colin LAM
Jeffrey Alexander
Kristina CHU
Barbara Eckert
Dylan GOLDMAN
Patrick Lin
Kalyani MANGIPUDI
Misha MEHTA
Arrash MOGHADDASI
Hai Nguyen
Natacha SORENSON
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of CA3124760A1 publication Critical patent/CA3124760A1/en
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10041—Use of virus, viral particle or viral elements as a vector
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
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    • C12N2795/10123—Virus like particles [VLP]
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10151—Methods of production or purification of viral material
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10351—Methods of production or purification of viral material
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    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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CA3124760A 2018-12-31 2019-12-22 Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems Pending CA3124760A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862787151P 2018-12-31 2018-12-31
US62/787151 2018-12-31
US201962926989P 2019-10-28 2019-10-28
US62/926989 2019-10-28
PCT/EP2019/086888 WO2020141124A2 (en) 2018-12-31 2019-12-22 Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems

Publications (1)

Publication Number Publication Date
CA3124760A1 true CA3124760A1 (en) 2020-07-09

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CA3124760A Pending CA3124760A1 (en) 2018-12-31 2019-12-22 Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems

Country Status (9)

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US (2) US11572595B2 (https=)
EP (1) EP3906304A2 (https=)
JP (1) JP7636328B2 (https=)
KR (1) KR102876612B1 (https=)
CN (1) CN113272424A (https=)
AU (1) AU2019419691B2 (https=)
CA (1) CA3124760A1 (https=)
SG (1) SG11202107109SA (https=)
WO (1) WO2020141124A2 (https=)

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CN108410825B (zh) * 2018-04-20 2022-09-20 南京农业大学 一种噬菌体鸡尾酒及其应用
KR20220066303A (ko) 2019-09-11 2022-05-24 더 스크립스 리서치 인스티튜트 항바이러스 전구약물 및 이의 약제학적 조성물
WO2021188959A1 (en) * 2020-03-20 2021-09-23 Gilead Sciences, Inc. Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
WO2023187041A1 (en) * 2022-03-30 2023-10-05 Biological Research Centre Metagenomic libraries
CN115927214B (zh) * 2022-12-21 2024-03-22 暨南大学 基于双元系统高效改变噬菌体制剂宿主范围的方法及其应用
EP4621049A1 (en) * 2024-03-19 2025-09-24 Invitris GmbH Multispecific particles

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WO2020141124A2 (en) 2020-07-09
JP7636328B2 (ja) 2025-02-26
KR20210110826A (ko) 2021-09-09
AU2019419691A1 (en) 2021-07-08
CN113272424A (zh) 2021-08-17
US20200208226A1 (en) 2020-07-02
JP2022515857A (ja) 2022-02-22
EP3906304A2 (en) 2021-11-10
WO2020141124A3 (en) 2020-08-13
US20230272491A1 (en) 2023-08-31
US11572595B2 (en) 2023-02-07
SG11202107109SA (en) 2021-07-29
AU2019419691B2 (en) 2025-09-11
KR102876612B1 (ko) 2025-10-24

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