KR102743887B1 - 장기-작용성 gip 펩타이드 유사체 - Google Patents

장기-작용성 gip 펩타이드 유사체 Download PDF

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KR102743887B1
KR102743887B1 KR1020197034279A KR20197034279A KR102743887B1 KR 102743887 B1 KR102743887 B1 KR 102743887B1 KR 1020197034279 A KR1020197034279 A KR 1020197034279A KR 20197034279 A KR20197034279 A KR 20197034279A KR 102743887 B1 KR102743887 B1 KR 102743887B1
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seq
hgip
amino acid
peptide
gip
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KR20200014287A (ko
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메테 마리 로센킬데
젠스 줄 홀스트
라에르케 슈미트 가스베제르그
알렉산더 호바드 스파레-울리히
마리아 버 노르드스코브 가베
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유니버시티 오브 코펜하겐
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
KR1020197034279A 2017-05-31 2018-05-31 장기-작용성 gip 펩타이드 유사체 Active KR102743887B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628.3 2017-05-31
EP17173628 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

Publications (2)

Publication Number Publication Date
KR20200014287A KR20200014287A (ko) 2020-02-10
KR102743887B1 true KR102743887B1 (ko) 2024-12-19

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KR1020197034279A Active KR102743887B1 (ko) 2017-05-31 2018-05-31 장기-작용성 gip 펩타이드 유사체

Country Status (10)

Country Link
US (1) US11572399B2 (https=)
EP (2) EP3630806B1 (https=)
JP (1) JP2020521784A (https=)
KR (1) KR102743887B1 (https=)
CN (1) CN110691788B (https=)
AU (1) AU2018276434B2 (https=)
BR (1) BR112019025195A8 (https=)
ES (1) ES2972848T3 (https=)
PL (1) PL3630806T3 (https=)
WO (1) WO2018220123A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10968266B2 (en) 2014-09-05 2021-04-06 University Of Copenhagen GIP peptide analogues
PL3630806T3 (pl) 2017-05-31 2024-05-13 The University Of Copenhagen Analogi peptydów gip o długotrwałym działaniu
KR102379958B1 (ko) 2018-05-04 2022-04-01 노보 노르디스크 에이/에스 Gip 유도체 및 이의 용도
CN121449721A (zh) * 2018-12-03 2026-02-03 安泰博医药 经修饰的gip肽类似物
CA3157387A1 (en) * 2019-12-03 2021-06-10 Mette Marie Rosenkilde Optimized gip peptide analogues
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

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US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6384016B1 (en) 1998-03-13 2002-05-07 Novo Nordisk A/S Stabilized aqueous peptide solutions
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JP2003522099A (ja) 1998-02-27 2003-07-22 ノボ ノルディスク アクティーゼルスカブ 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン
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US20050272652A1 (en) 1999-03-29 2005-12-08 Gault Victor A Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
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GB0404124D0 (en) * 2004-02-25 2004-03-31 Univ Ulster Antagonists of GIP
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US20030232761A1 (en) 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20050059605A1 (en) 2003-01-31 2005-03-17 Krishna Peri Chemically modified metabolites of regulatory peptides and methods of producing and using same
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BRPI0606992A2 (pt) 2005-02-11 2009-07-28 Amylin Pharmaceuticals Inc análogo e polipeptìdeos hìbridos de gip com propriedades selecionáveis
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EP2528618A4 (en) 2010-01-27 2015-05-27 Univ Indiana Res & Tech Corp GLUCAGON ANTAGONISTE AND GIP AGONISTS CONJUGATES AND COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES AND ADIPOSITAS
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SG191252A1 (en) * 2010-12-22 2013-07-31 Marcadia Biotech Inc Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides
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WO2018069442A1 (en) * 2016-10-12 2018-04-19 University Of Copenhagen Peptide dual agonists of gipr and glp2r
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CN110087686A (zh) 2016-12-26 2019-08-02 花王株式会社 认知功能改善剂
CN110139672A (zh) 2016-12-26 2019-08-16 花王株式会社 运动调节功能提高剂
PL3630806T3 (pl) 2017-05-31 2024-05-13 The University Of Copenhagen Analogi peptydów gip o długotrwałym działaniu

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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

Also Published As

Publication number Publication date
EP4361173A2 (en) 2024-05-01
CN110691788A (zh) 2020-01-14
WO2018220123A1 (en) 2018-12-06
EP3630806B1 (en) 2024-01-10
BR112019025195A8 (pt) 2020-07-07
BR112019025195A2 (pt) 2020-06-23
EP4361173A3 (en) 2024-07-03
EP3630806A1 (en) 2020-04-08
US20200087373A1 (en) 2020-03-19
AU2018276434B2 (en) 2021-12-16
CN110691788B (zh) 2024-05-31
JP2020521784A (ja) 2020-07-27
ES2972848T3 (es) 2024-06-17
AU2018276434A1 (en) 2020-01-02
CA3064510A1 (en) 2018-12-06
US11572399B2 (en) 2023-02-07
KR20200014287A (ko) 2020-02-10
PL3630806T3 (pl) 2024-05-13

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