BR112019025195A8 - análogos do peptídeo gip de ação prolongada - Google Patents

análogos do peptídeo gip de ação prolongada

Info

Publication number
BR112019025195A8
BR112019025195A8 BR112019025195A BR112019025195A BR112019025195A8 BR 112019025195 A8 BR112019025195 A8 BR 112019025195A8 BR 112019025195 A BR112019025195 A BR 112019025195A BR 112019025195 A BR112019025195 A BR 112019025195A BR 112019025195 A8 BR112019025195 A8 BR 112019025195A8
Authority
BR
Brazil
Prior art keywords
long
peptide analogues
gip peptide
acting
acting gip
Prior art date
Application number
BR112019025195A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112019025195A2 (pt
Inventor
Hovard Sparre-Ul­Rich Alexander
Juul Holst Jens
Smidt Gasbjerg Lærke
Buur Nord­Skov Gabe Maria
Marie Rosenkilde Mette
Original Assignee
Univ Copenhagen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Copenhagen filed Critical Univ Copenhagen
Publication of BR112019025195A2 publication Critical patent/BR112019025195A2/pt
Publication of BR112019025195A8 publication Critical patent/BR112019025195A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
BR112019025195A 2017-05-31 2018-05-31 análogos do peptídeo gip de ação prolongada BR112019025195A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628 2017-05-31
US17173628.3 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

Publications (2)

Publication Number Publication Date
BR112019025195A2 BR112019025195A2 (pt) 2020-06-23
BR112019025195A8 true BR112019025195A8 (pt) 2020-07-07

Family

ID=59021262

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019025195A BR112019025195A8 (pt) 2017-05-31 2018-05-31 análogos do peptídeo gip de ação prolongada

Country Status (10)

Country Link
US (1) US11572399B2 (https=)
EP (2) EP4361173A3 (https=)
JP (1) JP2020521784A (https=)
KR (1) KR102743887B1 (https=)
CN (1) CN110691788B (https=)
AU (1) AU2018276434B2 (https=)
BR (1) BR112019025195A8 (https=)
ES (1) ES2972848T3 (https=)
PL (1) PL3630806T3 (https=)
WO (1) WO2018220123A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2685987T3 (es) 2014-09-05 2018-10-15 University Of Copenhagen Análogos de péptidos gip
KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체
US11633459B2 (en) 2018-05-04 2023-04-25 Novo Nordisk A/S GIP derivatives and uses thereof
SG11202105586YA (en) 2018-12-03 2021-06-29 Antag Therapeutics Aps Modified gip peptide analogues
US20250346647A2 (en) * 2019-12-03 2025-11-13 Antag Therapeutics Aps Optimized GIP Peptide Analogues
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

Family Cites Families (40)

* Cited by examiner, † Cited by third party
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US5869602A (en) 1995-03-17 1999-02-09 Novo Nordisk A/S Peptide derivatives
US6384016B1 (en) 1998-03-13 2002-05-07 Novo Nordisk A/S Stabilized aqueous peptide solutions
US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
IL128332A0 (en) 1996-08-30 2000-01-31 Novo Nordisk As GLP-1 derivatives
WO1998024464A1 (en) 1996-12-03 1998-06-11 Trustees Of Boston University Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)
ATE197408T1 (de) 1998-01-30 2000-11-11 Novo Nordisk As Eine injektionsspritze
JP2003522099A (ja) 1998-02-27 2003-07-22 ノボ ノルディスク アクティーゼルスカブ 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン
EP1119625B1 (en) 1998-10-07 2005-06-29 Medical College Of Georgia Research Institute, Inc. Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
CZ295044B6 (cs) 1998-12-07 2005-05-18 Societe De Conseils De Recherches Et D'application Analogy GLP-1, mající kyselinu aminoizomáselnou na pozicích 8 a 35, jejich použití a farmaceutické prostředky je obsahující
GB0404124D0 (en) 2004-02-25 2004-03-31 Univ Ulster Antagonists of GIP
US20050272652A1 (en) 1999-03-29 2005-12-08 Gault Victor A Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
US6921748B1 (en) 1999-03-29 2005-07-26 Uutech Limited Analogs of gastric inhibitory polypeptide and their use for treatment of diabetes
IL155812A0 (en) 2000-12-07 2003-12-23 Lilly Co Eli Glp-1 fusion proteins
US20030232761A1 (en) 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
WO2004067548A2 (en) 2003-01-31 2004-08-12 Theratechnologies Inc. Chemically modified metabolites of regulatory peptides and methods of producing and using same
KR20070115947A (ko) 2005-02-11 2007-12-06 아밀린 파마슈티칼스, 인크. 선택가능한 특성들을 가지는 ｇｉｐ 유사체 및 하이브리드폴리펩타이드
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
TWI362392B (en) 2005-03-18 2012-04-21 Novo Nordisk As Acylated glp-1 compounds
WO2007109354A2 (en) 2006-03-21 2007-09-27 Amylin Pharmaceuticals, Inc. Peptide-peptidase inhibitor conjugates and methods of using same
WO2008021560A2 (en) * 2006-08-17 2008-02-21 Amylin Pharmaceuticals, Inc. Dpp-iv resistant gip hybrid polypeptides with selectable properties
ES2574835T3 (es) 2008-08-07 2016-06-22 Ipsen Pharma S.A.S. Análogos del polipéptido insulinotrópico dependiente de glucosa
WO2010016940A2 (en) 2008-08-07 2010-02-11 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide
AU2009280021B2 (en) 2008-08-07 2012-10-04 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
KR20110043687A (ko) 2008-08-07 2011-04-27 입센 파마 에스.에이.에스 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드의 절단형 유사체
WO2010016936A1 (en) 2008-08-07 2010-02-11 Ipsen Pharma S.A.S. Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide
KR20120123443A (ko) * 2010-01-27 2012-11-08 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 대사 장애 및 비만 치료용 글루카곤 길항제-ｇｉｐ 항진제 콘쥬게이트
US9023986B2 (en) 2010-10-25 2015-05-05 Hoffmann-La Roche Inc. Glucose-dependent insulinotropic peptide analogs
WO2012088379A2 (en) * 2010-12-22 2012-06-28 Marcadia Biotech, Inc. Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides
US20140377171A1 (en) * 2011-06-10 2014-12-25 Jean Claude Reubi Imaging and Treatment of Neuroendocrine Tumors with Glucose - Dependent Insulinotropic Polypeptide or Analogues or Antagonists Thereof
US9453062B2 (en) 2011-06-10 2016-09-27 Beijing Hanmi Pharmaceutical Co., Ltd. Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof
JP2016521253A (ja) 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ
ES2685987T3 (es) * 2014-09-05 2018-10-15 University Of Copenhagen Análogos de péptidos gip
KR102620911B1 (ko) * 2014-10-29 2024-01-05 질랜드 파마 에이/에스 Gip 효능제 화합물 및 방법
WO2016205488A1 (en) 2015-06-17 2016-12-22 The California Institute For Biomedical Research Modified therapeutic agents and compositions thereof
EP3526242A1 (en) * 2016-10-12 2019-08-21 University of Copenhagen Peptide dual agonists of gipr and glp2r
CN110099694A (zh) 2016-12-26 2019-08-06 花王株式会社 低体温改善剂
JP7165495B2 (ja) 2016-12-26 2022-11-04 花王株式会社 運動調節機能向上剤
WO2018124010A1 (ja) 2016-12-26 2018-07-05 花王株式会社 認知機能改善剤
KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체

Also Published As

Publication number Publication date
US20200087373A1 (en) 2020-03-19
JP2020521784A (ja) 2020-07-27
ES2972848T3 (es) 2024-06-17
CA3064510A1 (en) 2018-12-06
WO2018220123A1 (en) 2018-12-06
US11572399B2 (en) 2023-02-07
PL3630806T3 (pl) 2024-05-13
KR102743887B1 (ko) 2024-12-19
EP3630806B1 (en) 2024-01-10
AU2018276434B2 (en) 2021-12-16
BR112019025195A2 (pt) 2020-06-23
EP3630806A1 (en) 2020-04-08
AU2018276434A1 (en) 2020-01-02
CN110691788B (zh) 2024-05-31
CN110691788A (zh) 2020-01-14
EP4361173A2 (en) 2024-05-01
KR20200014287A (ko) 2020-02-10
EP4361173A3 (en) 2024-07-03

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]