CN110691788B - 长效gip肽类似物 - Google Patents

长效gip肽类似物 Download PDF

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Publication number
CN110691788B
CN110691788B CN201880036341.0A CN201880036341A CN110691788B CN 110691788 B CN110691788 B CN 110691788B CN 201880036341 A CN201880036341 A CN 201880036341A CN 110691788 B CN110691788 B CN 110691788B
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seq
hgip
gip
amino acid
fatty acid
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Chinese (zh)
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CN110691788A (zh
Inventor
M·M·罗森基尔德
J·J·霍尔斯特
L·S·加斯伯格
A·H·斯巴尔-乌尔里希
M·B·N·加布
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Københavns Universitet
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Københavns Universitet
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
CN201880036341.0A 2017-05-31 2018-05-31 长效gip肽类似物 Active CN110691788B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628.3 2017-05-31
EP17173628 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

Publications (2)

Publication Number Publication Date
CN110691788A CN110691788A (zh) 2020-01-14
CN110691788B true CN110691788B (zh) 2024-05-31

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Family Applications (1)

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CN201880036341.0A Active CN110691788B (zh) 2017-05-31 2018-05-31 长效gip肽类似物

Country Status (10)

Country Link
US (1) US11572399B2 (https=)
EP (2) EP4361173A3 (https=)
JP (1) JP2020521784A (https=)
KR (1) KR102743887B1 (https=)
CN (1) CN110691788B (https=)
AU (1) AU2018276434B2 (https=)
BR (1) BR112019025195A8 (https=)
ES (1) ES2972848T3 (https=)
PL (1) PL3630806T3 (https=)
WO (1) WO2018220123A1 (https=)

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ES2685987T3 (es) 2014-09-05 2018-10-15 University Of Copenhagen Análogos de péptidos gip
KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체
US11633459B2 (en) 2018-05-04 2023-04-25 Novo Nordisk A/S GIP derivatives and uses thereof
SG11202105586YA (en) 2018-12-03 2021-06-29 Antag Therapeutics Aps Modified gip peptide analogues
US20250346647A2 (en) * 2019-12-03 2025-11-13 Antag Therapeutics Aps Optimized GIP Peptide Analogues
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

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WO2016205488A1 (en) 2015-06-17 2016-12-22 The California Institute For Biomedical Research Modified therapeutic agents and compositions thereof
EP3526242A1 (en) * 2016-10-12 2019-08-21 University of Copenhagen Peptide dual agonists of gipr and glp2r
CN110099694A (zh) 2016-12-26 2019-08-06 花王株式会社 低体温改善剂
JP7165495B2 (ja) 2016-12-26 2022-11-04 花王株式会社 運動調節機能向上剤
WO2018124010A1 (ja) 2016-12-26 2018-07-05 花王株式会社 認知機能改善剤
KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012088379A2 (en) * 2010-12-22 2012-06-28 Marcadia Biotech, Inc. Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

Also Published As

Publication number Publication date
US20200087373A1 (en) 2020-03-19
JP2020521784A (ja) 2020-07-27
ES2972848T3 (es) 2024-06-17
CA3064510A1 (en) 2018-12-06
WO2018220123A1 (en) 2018-12-06
US11572399B2 (en) 2023-02-07
BR112019025195A8 (pt) 2020-07-07
PL3630806T3 (pl) 2024-05-13
KR102743887B1 (ko) 2024-12-19
EP3630806B1 (en) 2024-01-10
AU2018276434B2 (en) 2021-12-16
BR112019025195A2 (pt) 2020-06-23
EP3630806A1 (en) 2020-04-08
AU2018276434A1 (en) 2020-01-02
CN110691788A (zh) 2020-01-14
EP4361173A2 (en) 2024-05-01
KR20200014287A (ko) 2020-02-10
EP4361173A3 (en) 2024-07-03

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