KR102649543B1 - 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도 - Google Patents

캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도 Download PDF

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KR102649543B1
KR102649543B1 KR1020227033180A KR20227033180A KR102649543B1 KR 102649543 B1 KR102649543 B1 KR 102649543B1 KR 1020227033180 A KR1020227033180 A KR 1020227033180A KR 20227033180 A KR20227033180 A KR 20227033180A KR 102649543 B1 KR102649543 B1 KR 102649543B1
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cells
vector
disease
promoter
vectors
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KR20220136477A (ko
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애런 스리바스타바
리 종
세르게이 졸로투킨
조지 브이. 에스래니디
마비스 아그밴드지-맥케나
킴 엠. 반 블리에트
첸 링
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유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드
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KR1020227033180A 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도 Active KR102649543B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13/899,481 2013-05-21
US13/899,481 US9920097B2 (en) 2007-04-09 2013-05-21 Capsid-modified rAAV vector compositions having improved transduction efficiencies, and methods of use
PCT/US2014/039015 WO2014193716A2 (en) 2013-05-21 2014-05-21 Capsid-modified, raav3 vector compositions and methods of use in gene therapy of human liver cancer
KR1020217027678A KR20210111878A (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도

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KR20220136477A KR20220136477A (ko) 2022-10-07
KR102649543B1 true KR102649543B1 (ko) 2024-03-21

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KR1020217027678A Ceased KR20210111878A (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
KR1020217008950A Active KR102298579B1 (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
KR1020227033180A Active KR102649543B1 (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
KR1020157036164A Active KR102234672B1 (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도

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KR1020217008950A Active KR102298579B1 (ko) 2013-05-21 2014-05-21 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도

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EP (2) EP2999791B1 (enExample)
JP (3) JP6628286B2 (enExample)
KR (4) KR20210111878A (enExample)
CN (3) CN105408486B (enExample)
AU (3) AU2014274457B2 (enExample)
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US10294281B2 (en) 2012-05-15 2019-05-21 University Of Florida Research Foundation, Incorporated High-transduction-efficiency rAAV vectors, compositions, and methods of use
US12358954B2 (en) 2012-05-15 2025-07-15 University Of Florida Research Foundation, Incorporated Capsid-modified rAAV vector compositions and methods therefor
EP3633041A3 (en) 2013-09-26 2020-07-29 University of Florida Research Foundation, Inc. Synthetic combinatorial aav capsid library for targeted gene therapy
EP3151866B1 (en) 2014-06-09 2023-03-08 Voyager Therapeutics, Inc. Chimeric capsids
GB201420139D0 (en) 2014-11-12 2014-12-24 Ucl Business Plc Factor IX gene therapy
US20180030096A1 (en) 2015-02-03 2018-02-01 University Of Florida Research Foundation, Inc. Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
GB201508026D0 (en) 2015-05-11 2015-06-24 Ucl Business Plc Capsid
PT3356390T (pt) 2015-09-28 2021-04-21 Univ Florida Métodos e composições para vetores virais que se evadem a anticorpos
US12188037B2 (en) 2015-10-22 2025-01-07 University Of Florida Research Foundation, Incorporated Synthetic combinatorial AAV3 capsid library
CN116478254A (zh) 2015-12-14 2023-07-25 北卡罗来纳大学教堂山分校 增强细小病毒载体递送的修饰衣壳蛋白
US20190262373A1 (en) * 2016-08-16 2019-08-29 The University Of North Carolina At Chapel Hill Methods and compositions for targeted gene transfer
WO2018035503A1 (en) * 2016-08-18 2018-02-22 The Regents Of The University Of California Crispr-cas genome engineering via a modular aav delivery system
WO2018156654A1 (en) 2017-02-21 2018-08-30 University Of Florida Research Foundation, Incorporated Modified aav capsid proteins and uses thereof
CN110892062A (zh) 2017-05-05 2020-03-17 佛罗里达大学研究基金会 表达耳畸蛋白的组合物和方法
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