KR102626805B1 - 젤라틴 정제법 - Google Patents

젤라틴 정제법 Download PDF

Info

Publication number
KR102626805B1
KR102626805B1 KR1020177017471A KR20177017471A KR102626805B1 KR 102626805 B1 KR102626805 B1 KR 102626805B1 KR 1020177017471 A KR1020177017471 A KR 1020177017471A KR 20177017471 A KR20177017471 A KR 20177017471A KR 102626805 B1 KR102626805 B1 KR 102626805B1
Authority
KR
South Korea
Prior art keywords
gelatin
delete delete
lps
surfactant
triton
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020177017471A
Other languages
English (en)
Korean (ko)
Other versions
KR20180085677A (ko
Inventor
조셉 후베르투스 올리브
보른 베르가우웬
폴 스티븐스
Original Assignee
루셀롯 비브이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 루셀롯 비브이 filed Critical 루셀롯 비브이
Publication of KR20180085677A publication Critical patent/KR20180085677A/ko
Application granted granted Critical
Publication of KR102626805B1 publication Critical patent/KR102626805B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/20—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbon; comprising carbon obtained by carbonising processes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09H—PREPARATION OF GLUE OR GELATINE
    • C09H3/00—Isolation of glue or gelatine from raw materials, e.g. by extracting, by heating
    • C09H3/02—Purification of solutions of gelatine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Water Supply & Treatment (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Sustainable Development (AREA)
  • Materials Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Jellies, Jams, And Syrups (AREA)
KR1020177017471A 2014-11-26 2015-12-18 젤라틴 정제법 Active KR102626805B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2013880A NL2013880B1 (en) 2014-11-26 2014-11-26 Gelatin purification.
PCT/NL2015/050832 WO2016085345A1 (en) 2014-11-26 2015-11-26 Gelatin purification

Publications (2)

Publication Number Publication Date
KR20180085677A KR20180085677A (ko) 2018-07-27
KR102626805B1 true KR102626805B1 (ko) 2024-01-22

Family

ID=52463078

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177017471A Active KR102626805B1 (ko) 2014-11-26 2015-12-18 젤라틴 정제법

Country Status (16)

Country Link
US (1) US10155805B2 (enExample)
EP (1) EP3223869B1 (enExample)
JP (2) JP6860766B2 (enExample)
KR (1) KR102626805B1 (enExample)
CN (1) CN107580608B (enExample)
AR (1) AR102853A1 (enExample)
AU (1) AU2015354868B2 (enExample)
BR (1) BR112017010929A2 (enExample)
CA (1) CA2968672C (enExample)
DK (1) DK3223869T3 (enExample)
ES (1) ES2881951T3 (enExample)
HU (1) HUE056139T2 (enExample)
NL (1) NL2013880B1 (enExample)
PL (1) PL3223869T3 (enExample)
PT (1) PT3223869T (enExample)
WO (1) WO2016085345A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015121923A1 (de) * 2015-12-16 2017-06-22 Gelita Ag Gießmasse und Verfahren für die Herstellung von Gelatineprodukten
US11473004B2 (en) 2016-12-02 2022-10-18 University Of Wyoming Microemulsions and uses thereof to displace oil in heterogeneous porous media
EP3489314A1 (en) * 2017-11-23 2019-05-29 Rousselot B.V. Method for the preparation of gelatin hydrolysate having a low endotoxin content
DE102019130197A1 (de) * 2019-11-08 2021-05-12 Gelita Ag Verfahren zur Herstellung von Knochengelatine, und hergestellte Knochengelatine
BE1028324B1 (nl) 2020-05-19 2021-12-22 Rousselot Ge(meth)acryleerd gelatine laag in endotoxines
AR126103A1 (es) 2021-06-10 2023-09-13 Rousselot Bv Gelatina funcionalizada reticulable con baja actividad pirogénica
CN115739031B (zh) * 2021-09-02 2024-05-28 中国科学院理化技术研究所 壳聚糖或其衍生物在脱除明胶中内毒素的应用
BE1031466B1 (nl) 2023-04-11 2024-12-11 Rousselot Bv Het gebruik van vetalcoholpolyglycolether om endotoxine-activiteit en/of endotoxinen in collageenbevattende en/of van collageen afgeleide producten te verminderen
WO2025122009A1 (en) 2023-12-04 2025-06-12 Sentryx B.V. A method for purifying a gelatin

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005289841A (ja) * 2004-03-31 2005-10-20 Nippi:Kk 無菌ゼラチンの製造方法
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808314A (en) * 1987-09-18 1989-02-28 Scripps Clinic And Research Foundation Method for reducing bacterial endotoxin contamination in solutions of macromolecules
CA2128547A1 (en) * 1993-07-26 1995-01-27 Ronald Kompier Method for the separation of bacterial lipopolysaccharides from protein-containing solutions
DE19549420A1 (de) 1995-04-27 1997-09-18 Braun Melsungen Ag Verfahren zur simultanen extrakorporalen Elimination von Tumor-Nekrose Faktor alpha (TNF alpha) und bakteriellen Lipopolysacchariden (LPS) aus Vollblut oder/und Blutplasma
ATE405647T1 (de) 1999-11-12 2008-09-15 Fibrogen Inc Rekombinantes gelatin in impstoffen
JP4351461B2 (ja) * 2003-03-31 2009-10-28 新田ゼラチン株式会社 コラーゲンタンパク質からのエンドトキシン除去方法
DE102007024256A1 (de) 2007-05-16 2008-11-20 Gelita Ag Gefäßstent
WO2009015440A1 (en) 2007-08-02 2009-02-05 Aquatrek Pty Ltd Liquid diverter
ES2621452T3 (es) * 2008-06-19 2017-07-04 Bender Analytical Holding B.V. Método para retirar impurezas de material biopolimérico
DE102010037469A1 (de) * 2010-09-10 2012-03-15 Gelita Ag Verfahren zur Reduzierung des Endotoxingehalts in einem kollagenhaltigen Material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005289841A (ja) * 2004-03-31 2005-10-20 Nippi:Kk 無菌ゼラチンの製造方法
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン

Also Published As

Publication number Publication date
CN107580608B (zh) 2020-12-29
JP7009586B2 (ja) 2022-01-25
EP3223869B1 (en) 2021-06-09
PT3223869T (pt) 2021-07-29
AR102853A1 (es) 2017-03-29
HUE056139T2 (hu) 2022-01-28
DK3223869T3 (da) 2021-08-02
JP2018502066A (ja) 2018-01-25
AU2015354868A1 (en) 2017-06-15
CN107580608A (zh) 2018-01-12
JP2021008480A (ja) 2021-01-28
PL3223869T3 (pl) 2021-11-15
JP6860766B2 (ja) 2021-04-21
WO2016085345A1 (en) 2016-06-02
AU2015354868B2 (en) 2020-03-12
ES2881951T3 (es) 2021-11-30
EP3223869A1 (en) 2017-10-04
US20170342130A1 (en) 2017-11-30
BR112017010929A2 (pt) 2018-02-14
CA2968672A1 (en) 2016-06-02
CA2968672C (en) 2021-05-04
NL2013880B1 (en) 2016-10-11
US10155805B2 (en) 2018-12-18
KR20180085677A (ko) 2018-07-27

Similar Documents

Publication Publication Date Title
KR102626805B1 (ko) 젤라틴 정제법
CN102099379A (zh) 用于从生物聚合物材料中去除杂质的方法
US20240034909A1 (en) Method for the preparation of gelatin hydrolysate having a low endotoxin content
Sun et al. Recovery of lysozyme from aqueous solution by polyelectrolyte precipitation with sodium alginate
CA2551564C (en) A simplified method to retrieve chitosan from acidic solutions thereof
Li et al. Complexation of pea albumins with anionic polysaccharides and purification of PA1a
WO2006067987A1 (ja) 中性のキトサンヒドロゲルおよびその製造方法
CN116253809B (zh) 一种去除壳聚糖中内毒素的方法
JP5100980B2 (ja) 化学物質の精製方法
RU2765951C1 (ru) Способ очистки гиалуроната от эндотоксинов
WO2025122009A1 (en) A method for purifying a gelatin
US20230049682A1 (en) Protein Separation
EP2233144A1 (en) Chitosan-containing compositions and process for production thereof
WO2018066595A1 (ja) コラーゲン組成物

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170623

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
AMND Amendment
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20201217

Comment text: Request for Examination of Application

PN2301 Change of applicant

Patent event date: 20210120

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230321

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230904

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230321

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

X091 Application refused [patent]
AMND Amendment
PX0901 Re-examination

Patent event code: PX09011S01I

Patent event date: 20230904

Comment text: Decision to Refuse Application

Patent event code: PX09012R01I

Patent event date: 20230621

Comment text: Amendment to Specification, etc.

Patent event code: PX09012R01I

Patent event date: 20201217

Comment text: Amendment to Specification, etc.

PX0701 Decision of registration after re-examination

Patent event date: 20231211

Comment text: Decision to Grant Registration

Patent event code: PX07013S01D

Patent event date: 20231205

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

Patent event date: 20230904

Comment text: Decision to Refuse Application

Patent event code: PX07011S01I

Patent event date: 20230621

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

Patent event date: 20201217

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20240115

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20240116

End annual number: 3

Start annual number: 1

PG1601 Publication of registration