KR102624543B1 - 인시류에 대하여 활성인 살충 독소 단백질 - Google Patents

인시류에 대하여 활성인 살충 독소 단백질 Download PDF

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KR102624543B1
KR102624543B1 KR1020197022233A KR20197022233A KR102624543B1 KR 102624543 B1 KR102624543 B1 KR 102624543B1 KR 1020197022233 A KR1020197022233 A KR 1020197022233A KR 20197022233 A KR20197022233 A KR 20197022233A KR 102624543 B1 KR102624543 B1 KR 102624543B1
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glu
val
asn
ile
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KR20190103254A (ko
Inventor
제임스 에이. 바움
데이비드 제이. 보웬
캐서린 에이. 차이
데이비드 제이. 치
윌리엄 피. 클린턴
크리스탈 엘. 다트
리 잉그리쉬
스타니슬라프 플라신스키
빅터 엠. 구조브
케빈 에이. 자렐
우마 알. 케사나팔리
토마스 엠. 말바르
로버트 엠. 맥캐롤
제이슨 에스. 밀리건
제이 피. 모건스턴
데보라 지. 러커
사라 에이. 살바도르
템플 에프. 스미스
카를로스 이. 소토
콜린 엠. 스털츠
브라이언 엠. 투르크직
타이 티. 본
모리츠 더블유. 에프. 에프. 본 리첸버그
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몬산토 테크놀로지 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10—Animals; Substances produced thereby or obtained therefrom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
    • A01N63/22—Bacillus
    • A01N63/23—B. thuringiensis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00—Arthropodicides
    • A01P7/04—Insecticides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Environmental Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Insects & Arthropods (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020197022233A 2017-01-12 2018-01-11 인시류에 대하여 활성인 살충 독소 단백질 Active KR102624543B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762445313P 2017-01-12 2017-01-12
US62/445,313 2017-01-12
PCT/US2018/013298 WO2018132556A1 (en) 2017-01-12 2018-01-11 Pesticidal toxin proteins active against lepidopteran insects

Publications (2)

Publication Number Publication Date
KR20190103254A KR20190103254A (ko) 2019-09-04
KR102624543B1 true KR102624543B1 (ko) 2024-01-15

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US (4) US10703782B2 (https=)
EP (1) EP3568485A4 (https=)
JP (1) JP7264815B2 (https=)
KR (1) KR102624543B1 (https=)
CN (3) CN110267976B (https=)
AR (1) AR110748A1 (https=)
BR (1) BR112019014278A2 (https=)
CA (2) CA3049658A1 (https=)
CO (1) CO2019008595A2 (https=)
CR (1) CR20190367A (https=)
MX (2) MX388347B (https=)
PH (1) PH12019501600A1 (https=)
PY (1) PY1801756A (https=)
UA (1) UA128156C2 (https=)
UY (1) UY37567A (https=)
WO (1) WO2018132556A1 (https=)
ZA (1) ZA201904418B (https=)

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US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN110982829B (zh) * 2019-12-23 2021-10-29 隆平生物技术(海南)有限公司 一种用于作物抗虫害的基因组合及其载体和应用
US20230137535A1 (en) * 2020-03-20 2023-05-04 Bayer Aktiengesellschaft Composition comprising multiple baculoviruses to target difficult insect species
CN116670155A (zh) 2020-12-21 2023-08-29 孟山都技术公司 新型昆虫抑制性蛋白质
UY39585A (es) 2020-12-23 2022-07-29 Monsanto Technology Llc Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas
WO2022146874A1 (en) 2020-12-31 2022-07-07 Monsanto Technology Llc Novel insect inhibitory proteins
CN113793639B (zh) * 2021-08-03 2024-01-05 杭州瑞丰生物科技有限公司 一种管理玉米螟对Bt毒素抗性的方法
WO2023156906A1 (en) * 2022-02-15 2023-08-24 Futuragene Israel Ltd A bacillus thuringiensis pesticidal protein (bt pp) combination useful for plant protection
CN114657276B (zh) * 2022-03-04 2023-07-07 江汉大学 检测水稻转基因品系的引物对组合、试剂盒及检测方法
CN115491428B (zh) * 2022-03-04 2025-09-12 江汉大学 检测棉花转基因品系的引物对组合、试剂盒及检测方法
CN120647736A (zh) * 2023-10-27 2025-09-16 安徽农业大学 一种杀虫蛋白及其在防治鳞翅目昆虫中的应用
CN120718122B (zh) * 2025-08-18 2025-12-02 隆平生物技术(海南)有限公司 一种提高植物抗虫害特性的抗虫蛋白Cry166及其应用

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US20120035135A1 (en) 2008-12-29 2012-02-09 Bayer Cropscience Ag Treatment of Transgenic Crops with Mixtures of Fiproles and Chloronicotinyls
WO2013134734A2 (en) 2012-03-09 2013-09-12 Vestaron Corporation Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
WO2017003811A1 (en) * 2015-07-01 2017-01-05 Syngenta Participations Ag Compositions and methods for controlling plant pests

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Publication number Priority date Publication date Assignee Title
US20120035135A1 (en) 2008-12-29 2012-02-09 Bayer Cropscience Ag Treatment of Transgenic Crops with Mixtures of Fiproles and Chloronicotinyls
WO2013134734A2 (en) 2012-03-09 2013-09-12 Vestaron Corporation Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
US20150148288A1 (en) 2012-03-09 2015-05-28 Vestaron Corporation Toxic Peptide Production, Peptide Expression in Plants and Combinations of Cysteine Rich Peptides
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
WO2017003811A1 (en) * 2015-07-01 2017-01-05 Syngenta Participations Ag Compositions and methods for controlling plant pests

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MX2021011210A (es) 2021-10-22
CA3049658A1 (en) 2018-07-19
PH12019501600A1 (en) 2020-02-24
AR110748A1 (es) 2019-05-02
EP3568485A4 (en) 2021-04-14
CO2019008595A2 (es) 2019-09-30
RU2019125252A (ru) 2021-02-12
CR20190367A (es) 2019-09-25
CN110267976B (zh) 2024-01-26
JP7264815B2 (ja) 2023-04-25
CN117947082A (zh) 2024-04-30
UY37567A (es) 2018-08-31
EP3568485A1 (en) 2019-11-20
MX388347B (es) 2025-03-19
US20200369733A1 (en) 2020-11-26
CA3229266A1 (en) 2018-07-19
WO2018132556A1 (en) 2018-07-19
US20230348543A1 (en) 2023-11-02
US20180208631A1 (en) 2018-07-26
US11702455B2 (en) 2023-07-18
BR112019014278A2 (pt) 2020-03-03
US20250163110A1 (en) 2025-05-22
JP2020503879A (ja) 2020-02-06
US10703782B2 (en) 2020-07-07
CN110267976A (zh) 2019-09-20
PY1801756A (es) 2018-10-01
CN117947081A (zh) 2024-04-30
ZA201904418B (en) 2020-12-23
MX2019008357A (es) 2019-12-02
RU2019125252A3 (https=) 2021-10-18
UA128156C2 (uk) 2024-04-24
US12240874B2 (en) 2025-03-04
KR20190103254A (ko) 2019-09-04

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