KR102568313B1 - 현탁액 내 세포를 분리하기 위한 원심 분리 시스템 - Google Patents

현탁액 내 세포를 분리하기 위한 원심 분리 시스템 Download PDF

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Publication number
KR102568313B1
KR102568313B1 KR1020207031612A KR20207031612A KR102568313B1 KR 102568313 B1 KR102568313 B1 KR 102568313B1 KR 1020207031612 A KR1020207031612 A KR 1020207031612A KR 20207031612 A KR20207031612 A KR 20207031612A KR 102568313 B1 KR102568313 B1 KR 102568313B1
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South Korea
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filtrate
concentrate
opening
pump
chamber
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English (en)
Korean (ko)
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KR20210018796A (ko
Inventor
에스 케슬러
티 마로
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뉴메틱 스케일 코포레이션
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Priority to KR1020227009017A priority Critical patent/KR102568314B1/ko
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Program control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020207031612A 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템 Active KR102568313B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227009017A KR102568314B1 (ko) 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08
US62/682,376 2018-06-08
PCT/US2019/035855 WO2019236895A1 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227009017A Division KR102568314B1 (ko) 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템

Publications (2)

Publication Number Publication Date
KR20210018796A KR20210018796A (ko) 2021-02-18
KR102568313B1 true KR102568313B1 (ko) 2023-08-18

Family

ID=68770662

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020207031612A Active KR102568313B1 (ko) 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템
KR1020227009017A Active KR102568314B1 (ko) 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020227009017A Active KR102568314B1 (ko) 2018-06-08 2019-06-06 현탁액 내 세포를 분리하기 위한 원심 분리 시스템

Country Status (8)

Country Link
EP (1) EP3801920A4 (https=)
JP (1) JP7336467B2 (https=)
KR (2) KR102568313B1 (https=)
CN (2) CN115254458A (https=)
AU (2) AU2019280856B2 (https=)
CA (1) CA3102600C (https=)
MX (2) MX2020011898A (https=)
WO (1) WO2019236895A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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US12350686B2 (en) * 2011-11-21 2025-07-08 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11878312B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US20230356111A1 (en) * 2020-08-22 2023-11-09 Sunil Mehta An automated centrifugation device and methods to continuously separate components from different mixtures
CN112798393A (zh) * 2021-02-01 2021-05-14 中博瑞康（北京）生物技术有限公司 一种大体积生物细胞液浓缩洗涤系统及其方法
CN114682397B (zh) * 2022-03-28 2024-03-15 浙江大学 锥形液液轴向离心分离器及分离监控装置
WO2023196391A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreator

Citations (1)

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US20150284671A1 (en) * 2008-04-22 2015-10-08 Pneumatic Scale Corporation Single use centrifuge system for highly concentrated and/or turbid feeds

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DE941267C (de) * 1950-01-19 1956-04-05 Separator Ab Schleudermaschine fuer die kontinuierliche Trennung und Austragung fester Bestandteile aus einem Fluessigkeitsgemisch
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JPH09192215A (ja) * 1996-01-17 1997-07-29 Takaharu Nakane 遠心ボウル
JP3313572B2 (ja) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション 血液処理用遠心分離器ボウル
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EP1688183A1 (fr) * 2005-02-03 2006-08-09 Jean-Denis Rochat Procede et dispositif jetable pour la separation par centrifugation d'un liquide physiologique
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Also Published As

Publication number Publication date
JP2021526957A (ja) 2021-10-11
AU2019280856A1 (en) 2020-12-17
CN112236236A (zh) 2021-01-15
KR20210018796A (ko) 2021-02-18
BR112020025083A2 (pt) 2021-03-23
AU2022204733B2 (en) 2024-07-04
MX2022003223A (es) 2022-04-12
AU2022204733A1 (en) 2022-07-21
EP3801920A4 (en) 2022-07-13
CA3102600A1 (en) 2019-12-12
MX2020011898A (es) 2021-01-15
AU2019280856B2 (en) 2022-06-30
WO2019236895A1 (en) 2019-12-12
CN115254458A (zh) 2022-11-01
EP3801920A1 (en) 2021-04-14
KR20220039841A (ko) 2022-03-29
JP7336467B2 (ja) 2023-08-31
KR102568314B1 (ko) 2023-08-18
CA3102600C (en) 2024-06-11

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