CA3102600C - Centrifuge system for separating cells in suspension - Google Patents

Centrifuge system for separating cells in suspension Download PDF

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Publication number
CA3102600C
CA3102600C CA3102600A CA3102600A CA3102600C CA 3102600 C CA3102600 C CA 3102600C CA 3102600 A CA3102600 A CA 3102600A CA 3102600 A CA3102600 A CA 3102600A CA 3102600 C CA3102600 C CA 3102600C
Authority
CA
Canada
Prior art keywords
centrate
concentrate
pump
opening
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3102600A
Other languages
English (en)
French (fr)
Other versions
CA3102600A1 (en
Inventor
S Kessler
T Marro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pneumatic Scale Corp
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of CA3102600A1 publication Critical patent/CA3102600A1/en
Application granted granted Critical
Publication of CA3102600C publication Critical patent/CA3102600C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Program control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3102600A 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension Active CA3102600C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08
US62/682,376 2018-06-08
PCT/US2019/035855 WO2019236895A1 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Publications (2)

Publication Number Publication Date
CA3102600A1 CA3102600A1 (en) 2019-12-12
CA3102600C true CA3102600C (en) 2024-06-11

Family

ID=68770662

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3102600A Active CA3102600C (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Country Status (8)

Country Link
EP (1) EP3801920A4 (https=)
JP (1) JP7336467B2 (https=)
KR (2) KR102568313B1 (https=)
CN (2) CN115254458A (https=)
AU (2) AU2019280856B2 (https=)
CA (1) CA3102600C (https=)
MX (2) MX2020011898A (https=)
WO (1) WO2019236895A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12350686B2 (en) * 2011-11-21 2025-07-08 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11878312B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US20230356111A1 (en) * 2020-08-22 2023-11-09 Sunil Mehta An automated centrifugation device and methods to continuously separate components from different mixtures
CN112798393A (zh) * 2021-02-01 2021-05-14 中博瑞康（北京）生物技术有限公司 一种大体积生物细胞液浓缩洗涤系统及其方法
CN114682397B (zh) * 2022-03-28 2024-03-15 浙江大学 锥形液液轴向离心分离器及分离监控装置
WO2023196391A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreator

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA894304A (en) * 1972-02-29 Fujisawa Mitsumaro Embossing film with compressed air on recessed drum and applying second film
DE941267C (de) * 1950-01-19 1956-04-05 Separator Ab Schleudermaschine fuer die kontinuierliche Trennung und Austragung fester Bestandteile aus einem Fluessigkeitsgemisch
CA1057254A (en) * 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
DE3231070A1 (de) * 1982-08-19 1984-08-23 Herwig 1000 Berlin Michel-Kim Vorrichtung zur austragung von in silos gelagerten stoffen
EP0257755B1 (en) * 1986-07-22 1991-07-03 Haemonetics Corporation Centrifuge bowl or rotor for plasmapheresis
US5318500A (en) * 1992-10-15 1994-06-07 Eli Lilly And Company Method for controlling intermittently discharged centrifuges
CH687505A5 (fr) * 1993-01-29 1996-12-31 Elp Rochat Séparateur centrifuge pour fluides.
US5637217A (en) * 1995-01-25 1997-06-10 Fleetguard, Inc. Self-driven, cone-stack type centrifuge
EP0868215B1 (en) * 1995-12-01 2002-01-30 Baker Hughes Incorporated Method and apparatus for controlling and monitoring continuous feed centrifuge
JPH09192215A (ja) * 1996-01-17 1997-07-29 Takaharu Nakane 遠心ボウル
JP3313572B2 (ja) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション 血液処理用遠心分離器ボウル
DE19715661A1 (de) * 1997-04-16 1998-10-22 Mann & Hummel Filter Zentrifugenrotor
JP3817079B2 (ja) * 1998-10-05 2006-08-30 テルモ株式会社 血液成分採取装置
AU2625000A (en) * 1999-01-26 2000-08-07 Fluid Equipment Development Company, Llc Rotating process chamber with integral pump and energy recovery turbine
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
EP1688183A1 (fr) * 2005-02-03 2006-08-09 Jean-Denis Rochat Procede et dispositif jetable pour la separation par centrifugation d'un liquide physiologique
US7628749B2 (en) * 2005-09-01 2009-12-08 Wagner Development Inc. Solids recovery using cross-flow microfilter and automatic piston discharge centrifuge
CN201094937Y (zh) * 2007-09-18 2008-08-06 江苏牡丹离心机制造有限公司 一种吊袋式离心机中的挤袋装置
US9222067B2 (en) * 2008-04-22 2015-12-29 Pneumatic Scale Corporation Single use centrifuge system for highly concentrated and/or turbid feeds
AU2009334385B2 (en) * 2008-12-29 2015-10-08 Wagner Development, Inc. Solids discharge centrifugal separator with disposable contact elements
SI3199511T1 (sl) * 2009-06-04 2020-07-31 Genomatica, Inc. Proces separacije komponent fermentacijske brozge
WO2012137086A1 (en) * 2011-04-08 2012-10-11 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
WO2015186057A1 (en) * 2014-06-04 2015-12-10 Biosafe S.A. System for multi-processing and separation of biological fluids
DE102014118289A1 (de) * 2014-12-10 2016-06-16 Gea Mechanical Equipment Gmbh Separator
US9833557B2 (en) * 2014-12-19 2017-12-05 Fenwal, Inc. Systems and methods for determining free plasma hemoglobin
DE102015105988B3 (de) * 2015-04-20 2016-05-25 Hiller Gmbh Vorrichtung zum kontinuierlichen Trennen fließfähiger Stoffe unterschiedlicher Dichte in einer Zentrifuge
WO2017011527A1 (en) * 2015-07-13 2017-01-19 Haemonetics Corporation System and method for removing fat from salvaged blood
EP3347134A4 (en) * 2015-09-07 2019-04-17 Mann+Hummel GmbH CLADDING WITH SEAL FOR ROTOR OF A CENTRIFUGAL SEPARATOR
CN106238229B (zh) * 2016-08-31 2018-07-24 苏州盛天力离心机制造有限公司 抽滤离心机转鼓组件

Also Published As

Publication number Publication date
JP2021526957A (ja) 2021-10-11
AU2019280856A1 (en) 2020-12-17
CN112236236A (zh) 2021-01-15
KR20210018796A (ko) 2021-02-18
KR102568313B1 (ko) 2023-08-18
BR112020025083A2 (pt) 2021-03-23
AU2022204733B2 (en) 2024-07-04
MX2022003223A (es) 2022-04-12
AU2022204733A1 (en) 2022-07-21
EP3801920A4 (en) 2022-07-13
CA3102600A1 (en) 2019-12-12
MX2020011898A (es) 2021-01-15
AU2019280856B2 (en) 2022-06-30
WO2019236895A1 (en) 2019-12-12
CN115254458A (zh) 2022-11-01
EP3801920A1 (en) 2021-04-14
KR20220039841A (ko) 2022-03-29
JP7336467B2 (ja) 2023-08-31
KR102568314B1 (ko) 2023-08-18

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